Research Topics
| Erhan PiskinSummaryAffiliation: Hacettepe University Country: Turkey Publications
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Detail Information
Publications
Molecularly designed water soluble, intelligent, nanosize polymeric carriersErhan Piskin
Chemical Engineering Department, TUBITAK Centre of Excellence, Hacettepe University, BIYOMUH, Ankara, Turkey
Int J Pharm 277:105-18. 2004..This paper summarizes some of our related studies in which NIPA and its copolymers were synthesized and used as intelligent carriers in diverse applications...
Stimuli-responsive polymers in gene deliveryErhan Piskin
Hacettepe University, Chemical Engineering Department, Bioengineering Division, Beytepe, Ankara, Turkey
Expert Rev Med Devices 2:501-9. 2005..Through the use of stimuli-responsive polymers as novel vectors for gene delivery, two benefits can be obtained: high gene expression efficiency and more selective gene expression...
Novel metal-chelate affinity adsorbent for purification of immunoglobulin-G from human plasmaAdil Denizli
Department of Chemistry, Hacettepe University, Ankara, Turkey
J Chromatogr B Analyt Technol Biomed Life Sci 795:93-103. 2003..7%. The metal-chelate affinity beads allowed one-step separation of HIgG from human plasma. The adsorption-desorption cycle was repeated 10 times using the same beads without noticeable loss in their HIgG adsorption capacity...
Imaging of poly(NIPA-co-MAH)-HIgG conjugate with scanning tunneling microscopyCengiz Kocum
Department of Chemical Engineering, Hacettepe University, Ankara, Turkey
J Biomater Sci Polym Ed 15:1513-20. 2004..5 V sample bias and a tunneling current of 10-20 pA, which clearly demonstrated the formation of conjugates...
Monosize polycationic nanoparticles as non-viral vectors for gene transfer to HeLa cellsGüldem Utkan Güven
Chemical Engineering Department and Bioengineering Division, Hacettepe University, and Biyomedtek, Beytepe, Ankara, Turkey
J Tissue Eng Regen Med 2:155-63. 2008..The GFP expression efficiency was unexpectedly high (up to 90%)...
BHK cell attachment and growth on EDA-plasma-modified poly(L-lactide/epsilon-caprolactone) biodegradable filmsO Aylin Gürpinar
Hacettepe University, Faculty of Science, Department of Biology, Beytepe, 06532 Ankara, Turkey
J Biomater Sci Polym Ed 14:589-600. 2003..There was no attachment in the first 12 h. Glow-discharge treatment increased significantly the attachment and growth. Pre-wetting with ethanol and cell culture medium was also increase significantly both the attachment and growth...
Biochips: focusing on surfaces and surface modificationErhan Piskin
Hacettepe University Center of Bioengineering and Bioengineering Division, and TUBITAK Center of Excellence BIYOMUH, Beytepe, Ankara, Turkey
Adv Exp Med Biol 553:149-66. 2004
In vitro transfection of HeLa cells with temperature sensitive polycationic copolymersMustafa Turk
Bioengineering Division, Chemical Engineering Department, and TUBITAK Center of Excellence BIYOMUH, Hacettepe University, Beytepe, Ankara 06530, Turkey
J Control Release 96:325-40. 2004..The best in vitro DNA uptake efficiency (70%) was achieved with the complex prepared with poly(NIPA)/PEI25B. However, poly(NIPA)/PEI25L was the most successful vector for an effective gene expression without any significant toxicity...
Poly(N-isopropylacrylamide) layers on silicon wafers as smart DNA-sensor platformsGokhan Demirel
Department of Chemical Engineering and Division of Bioengineering, Hacettepe University, and Biyomedtek, Beytepe, 06800 Ankara, Turkey
J Nanosci Nanotechnol 9:1865-71. 2009..These preliminary studies demonstrated that this approach can be used switch off and on the surface reactions on smart surface by using an external stimulus (temperature in this case)...
Cryogelation for preparation of novel biodegradable tissue-engineering scaffoldsNimet Bölgen
Hacettepe University, Chemical Engineering Department and Bioengineering Division, Beytepe, Ankara, Turkey
J Biomater Sci Polym Ed 18:1165-79. 2007..Their swelling abilities, compressive strengths and degradation in buffer solutions were found to be related with their structural properties which was controlled by changing the cryogelation recipe...
HIgG detection by histidine carrying AFM tips (cantilevers)M Oya Cinar
Baskent University, Ankara, Turkey
Artif Cells Blood Substit Immobil Biotechnol 36:340-51. 2008..We were able to measure HIgG concentration in aqueous media down to 0.055 pmol/micro l (8 mg/dl) concentration with this AFM based novel immunosensor...
Three-dimensional ingrowth of bone cells within biodegradable cryogel scaffolds in bioreactors at different regimesNimet Bölgen
Bioengineering Division, Chemical Engineering Department, Hacettepe University, Ankara, Turkey
Tissue Eng Part A 14:1743-50. 2008..Dynamic conditions (perfusion and/or compression) greatly improved cell ingrowth and extracellular matrix (ECM) synthesis. Alkaline phosphatase activity results confirmed the positive effect of dynamic conditions on bone cells...
