N Ozbek

Summary

Affiliation: Hacettepe University
Country: Turkey

Publications

  1. ncbi request reprint Purpura fulminans in a child with combined heterozygous prothrombin G20210A and factor V Leiden mutations
    N Ozbek
    Department of Pediatrics, Baskent University Faculty of Medicine, 6 Cadde No 72 3, 06490 Bahcelievler, Ankara, Turkey
    Ann Hematol 82:118-20. 2003
  2. ncbi request reprint Analysis of prothrombotic mutations and polymorphisms in children who developed thrombosis in the perioperative period of congenital cardiac surgery
    Namik Ozbek
    Department of Pediatrics, Baskent University, Faculty of Medicine, Ankara, Turkey
    Cardiol Young 15:19-25. 2005
  3. ncbi request reprint Dysplastic changes in the peripheral blood of children with microdeletion 22q11.2
    Namik Ozbek
    Baskent University Faculty of Medicine, Department of Pediatrics, Pediatric Hematology Unit, Ankara, Turkey
    Am J Hematol 77:126-31. 2004
  4. ncbi request reprint Relationship between small-for-gestational age births and maternal thrombophilic mutations
    N Ozbek
    Baskent University School of Medicine, Department of Medical Biology and Genetics, Baglica Kampusu, Ankara, Turkey
    Thromb Res 122:175-8. 2008
  5. doi request reprint Prevalence of thrombophilic mutations and ACE I/D polymorphism in Turkish ischemic stroke patients
    Gulay Celiker
    Department of Neurology Baskent University School of Medicine, Ankara, Turkey
    Clin Appl Thromb Hemost 15:415-20. 2009
  6. ncbi request reprint Prognostic value of the PAI-1 4G/5G polymorphism in invasive ductal carcinoma of the breast
    M C Yagmurdur
    Department of General Surgery, Baskent University Faculty of Medicine, Ankara, Turkey
    Int Surg 93:163-8. 2008
  7. doi request reprint Thrombosis in children with cardiac pathology: analysis of acquired and inherited risk factors
    Bulent Alioglu
    Department of Pediatric Hematology, Baskent University Faculty of Medicine, Ankara, Turkey
    Blood Coagul Fibrinolysis 19:294-304. 2008
  8. doi request reprint Gaucher disease with communicating hydrocephalus and cardiac involvement
    N Cindik
    Division of Pediatric Cardiology, Baskent University Hospital, Ankara, Turkey
    Clin Cardiol 33:E26-30. 2010
  9. doi request reprint Comparison of IL10 and IL2 genotypes of Turkish population with other populations
    A C Yazici
    Department of Biostatistics, Baskent University, Ankara, Turkey
    Int J Immunogenet 36:97-101. 2009
  10. ncbi request reprint Complete blood count parameters for healthy, small-for-gestational-age, full-term newborns
    E Ozyurek
    Hematology Section, Department of Pediatrics, Baskent University Faculty of Medicine, Ankara, Turkey
    Clin Lab Haematol 28:97-104. 2006

Collaborators

  • Alioglu Bulent
  • K Tokel
  • Zerrin Yilmaz
  • S T Kinik
  • Lale Olcay
  • Murat Derbent
  • A Kara
  • E Tuncbilek
  • Banu Bilezikci
  • Uri Seligsohn
  • Figen Ozcay
  • F Peyvandi
  • Bulent Alioglu
  • Zekai Avci
  • F Belgin Atac
  • Fatma Belgin Atac
  • Hasibe Verdi
  • Suleyman Ozkan
  • Aylin Tarcan
  • S M Kayiran
  • E Ozyurek
  • N Cindik
  • F O Hosnut
  • Ayse Canan Yazici
  • A C Yazici
  • Ozlem Yilmaz Ozbek
  • Gulay Celiker
  • B Varan
  • H Verdi
  • F B Atac
  • Zeynel Gokmen
  • Bin Zhang
  • M C Yagmurdur
  • Servet Ozkiraz
  • Emel Ozyurek
  • Berkan Gurakan
  • F Alehan
  • B T Yilmaz
  • B Gurakan
  • S Mercan
  • B Atac
  • A Tarcan
  • Ezgi Sezgin
  • Ayse Taneri
  • Deniz Anuk Ince
  • I Akkoyun
  • D Suren
  • Hande Gulcan
  • O Canan
  • M Gokdemir
  • Atilla Sezgin
  • Ufuk Can
  • Emrah Uguz
  • Sait Aslamaci
  • Ersin Ogus
  • Salih Ozcobanoglu
  • Johnny Mahlangu
  • I Isiklar
  • Marta Spreafico
  • Angela Yang
  • Petra Platzer
  • B H Ozdemir
  • Edward G D Tuddenham
  • Kandice Marchant
  • Mahmut Gokdemir
  • Randal J Kaufman
  • David Ginsburg
  • Tabitha Haw
  • Hakan Caner
  • Michael U Callaghan
  • Chunlei Zheng
  • Basar Atalay
  • Baris Malbora
  • M Haberal
  • N U Tutar
  • H Karakayali
  • S Cetintas
  • A Haberal
  • E Ogus
  • T Ceylan
  • B Alioglu
  • H T Akay
  • C Altay
  • M Turan
  • F N Ozdemir
  • N Bilgin
  • U Yakupoglu
  • H Caner
  • S Emir
  • T M Schroeder-Kurth

Detail Information

Publications31

  1. ncbi request reprint Purpura fulminans in a child with combined heterozygous prothrombin G20210A and factor V Leiden mutations
    N Ozbek
    Department of Pediatrics, Baskent University Faculty of Medicine, 6 Cadde No 72 3, 06490 Bahcelievler, Ankara, Turkey
    Ann Hematol 82:118-20. 2003
    ..We believe that the coexistence of more than one thrombophilic mutation contributed to the occurrence of severe thrombosis at a young age in this patient...
  2. ncbi request reprint Analysis of prothrombotic mutations and polymorphisms in children who developed thrombosis in the perioperative period of congenital cardiac surgery
    Namik Ozbek
    Department of Pediatrics, Baskent University, Faculty of Medicine, Ankara, Turkey
    Cardiol Young 15:19-25. 2005
    ..In this study, we investigated some of the above-mentioned mutations and polymorphisms in children who developed thrombosis in the perioperative period after correction of congenital cardiac malformations...
  3. ncbi request reprint Dysplastic changes in the peripheral blood of children with microdeletion 22q11.2
    Namik Ozbek
    Baskent University Faculty of Medicine, Department of Pediatrics, Pediatric Hematology Unit, Ankara, Turkey
    Am J Hematol 77:126-31. 2004
    ..2 have not been reported previously. We believe that certain gene(s) in the deleted region may be responsible for the myelodysplastic changes that we observed in our patients with this chromosomal abnormality...
  4. ncbi request reprint Relationship between small-for-gestational age births and maternal thrombophilic mutations
    N Ozbek
    Baskent University School of Medicine, Department of Medical Biology and Genetics, Baglica Kampusu, Ankara, Turkey
    Thromb Res 122:175-8. 2008
    ..01) mutations in MTHFR gene may be suggested as risk factors for SGA outcome in our population. Therefore, maternal screening of these two mutations in the first trimester of pregnancy could help in the assessment of patients...
  5. doi request reprint Prevalence of thrombophilic mutations and ACE I/D polymorphism in Turkish ischemic stroke patients
    Gulay Celiker
    Department of Neurology Baskent University School of Medicine, Ankara, Turkey
    Clin Appl Thromb Hemost 15:415-20. 2009
    ..2%, respectively, vs 39.3%; statistically significant, P = .034, P = .020). Our results may suggest that ACE D/D genotype is a risk factor for IS, particularly in those with stroke of undetermined etiology in the Turkish population...
  6. ncbi request reprint Prognostic value of the PAI-1 4G/5G polymorphism in invasive ductal carcinoma of the breast
    M C Yagmurdur
    Department of General Surgery, Baskent University Faculty of Medicine, Ankara, Turkey
    Int Surg 93:163-8. 2008
    ..004). The results of this study indicate that the 4G allele in the PAI 1 gene had a negative impact on local recurrence and disease-free survival of patients with clinical T(1)-2N0M0 IDC...
  7. doi request reprint Thrombosis in children with cardiac pathology: analysis of acquired and inherited risk factors
    Bulent Alioglu
    Department of Pediatric Hematology, Baskent University Faculty of Medicine, Ankara, Turkey
    Blood Coagul Fibrinolysis 19:294-304. 2008
    ....
  8. doi request reprint Gaucher disease with communicating hydrocephalus and cardiac involvement
    N Cindik
    Division of Pediatric Cardiology, Baskent University Hospital, Ankara, Turkey
    Clin Cardiol 33:E26-30. 2010
    ..Cardiac abnormalities represent a life-threatening presentation of the homozygous D409H mutation. Identification of this type is essential prior to initiating appropriate therapy with enzyme replacement and cardiac corrective surgery...
  9. doi request reprint Comparison of IL10 and IL2 genotypes of Turkish population with other populations
    A C Yazici
    Department of Biostatistics, Baskent University, Ankara, Turkey
    Int J Immunogenet 36:97-101. 2009
    ..Here we have used interleukin (IL)-10 (-592C/A, -819T/C, -1082G/A) and IL-2 (-330T/G) as genetic markers to study the relationship between Turkish population and other populations...
  10. ncbi request reprint Complete blood count parameters for healthy, small-for-gestational-age, full-term newborns
    E Ozyurek
    Hematology Section, Department of Pediatrics, Baskent University Faculty of Medicine, Ankara, Turkey
    Clin Lab Haematol 28:97-104. 2006
    ....
  11. ncbi request reprint Activated protein C resistance and false type 2 protein C deficiency detected after multiple shunt failures in a patient with hydrocephalus
    S M Kayiran
    Department of Pediatrics, , Faculty of Medicine, , Ankara, Turkey
    J Child Neurol 16:862-3. 2001
    ....
  12. doi request reprint Incidence of and risk factors for childhood thrombosis: a single-center experience in Ankara, Turkey
    Namik Ozbek
    Department of Pediatric Hematology, Baskent University Faculty of Medicine, Ankara, Turkey
    Pediatr Hematol Oncol 26:11-29. 2009
    ..Thrombosis should be considered a systemic disorder, and thrombotic patients should be evaluated with appropriate methods. Acquired and hereditary risk factors should be analyzed systematically in thrombotic patients...
  13. ncbi request reprint Analysis of 65 Turkish patients with congenital aplastic anemia (Fanconi anemia and non-Fanconi anemia): Hacettepe experience
    C Altay
    Department of Pediatrics, Pediatric Hematology Unit, Ihsan Dogramaci Children s Hospital, Hacettepe University, Ankara, Turkey
    Clin Genet 51:296-302. 1997
    ..Detailed examination of the pedigrees of all of patients indicated the presence of multiple congenital anomalies. In seven of 52 FA and one of 13 non-FA patients there was increased risk for AML and/or other cancers among family members...
  14. ncbi request reprint Role of genetic mutations in vascular access thrombosis among hemodialysis patients waiting for renal transplantation
    B Atac
    Baskent University Faculty of Medicine, Ankara, Turkey
    Transplant Proc 34:2030-2. 2002
  15. ncbi request reprint Cardiac transplant in a child with recurrent thrombosis due to congenital thrombophilic mutations
    Suleyman Ozkan
    Department of Cardiovascular Surgery, Baskent University School of Medicine, Ankara, Turkey
    Exp Clin Transplant 7:188-91. 2009
    ..Congenital risk factors should be evaluated in patients who have experienced a thromboembolic event before cardiac surgery...
  16. doi request reprint Awareness of glucose-6 phosphate-dehydrogenase deficiency in celiac disease
    F O Hosnut
    Department of Pediatric Gastroenterology, Hepatology and Nutrition, Baskent University Faculty of Medicine, Ankara, Turkey
    Acta Paediatr 99:786-8. 2010
    ..Conclusion: When vitamin K administration becomes necessary for correction of coagulopathy in patients with CD; glucose-6 phosphate-dehydrogenase deficiency should be considered...
  17. ncbi request reprint Subcutaneous fat necrosis of the newborn associated with anemia
    B Varan
    Department of Pediatrics, , Ankara, Turkey
    Pediatr Dermatol 16:381-3. 1999
    ..She developed SFN on the fourth postnatal day. Her condition improved after blood transfusions and the skin lesions resolved in 6 weeks. This appears to be the first report of SFN associated with anemia...
  18. ncbi request reprint Bone marrow failure with concurrent enteroviral infection in a newborn
    A Tarcan
    Department of Pediatrics, , Ankara, Turkey
    Pediatr Infect Dis J 20:719-21. 2001
    ..Subsequent investigation showed bone marrow failure. To our knowledge this is the first reported case of bone marrow failure with concomitant enteroviral infection...
  19. ncbi request reprint Successful use of recombinant factor VIIa (NovoSeven) during cardiac surgery in a pediatric patient with Glanzmann thrombasthenia
    B T Yilmaz
    Department of Pediatrics, Pediatric Hematology Unit, Baskent University Faculty of Medicine, 6 cad No 72 3 06490, Bahcelievler, Ankara, Turkey
    Pediatr Cardiol 26:843-5. 2005
    ..This report describes the use of rFVIIa to prevent serious bleeding during and after open-heart surgery in a child with Glanzmann thrombasthenia...
  20. ncbi request reprint Significant differences between capillary and venous complete blood counts in the neonatal period
    S M Kayiran
    Pediatrician, Baskent University Faculty of Medicine, Ankara, Turkey
    Clin Lab Haematol 25:9-16. 2003
    ..When interpreting results, the term 'peripheral blood' should be replaced with 'capillary blood' or 'venous blood' so that an accurate assessment can be made...
  21. doi request reprint Lack of association between FXIII-Val34Leu, FVII-323 del/ins, and transforming growth factor beta1 (915G/T) gene polymorphisms and bronchopulmonary dysplasia: a single-center study
    Fatma Belgin Atac
    Department of Medical Biology and Genetics, Baskent University School of Medicine, Ankara, Turkey
    DNA Cell Biol 29:13-8. 2010
    ....
  22. ncbi request reprint Successful use of recombinant factor VIIa (NovoSeven) during cardiac surgery in a pediatric patient with congenital factor XI deficiency
    Zekai Avci
    Department of Pediatric Hematology, Baskent University Faculty of Medicine, 6 Cadde, No 72 3, 06490 Bahcelievler, Ankara, Turkey
    Pediatr Cardiol 29:220-2. 2008
    ..There was no bleeding during and after surgery. rFVIIa treatment may be used successfully in children with severe FXI deficiency in major operations such as open heart surgery...
  23. ncbi request reprint False findings of low protein C activity in two children with Budd-Chiari syndrome and factor V Leiden mutation
    Figen Ozcay
    Department of Pediatrics, Baskent University, Faculty of Medicine, Ankara, Turkey
    Haematologia (Budap) 32:11-5. 2002
    ....
  24. doi request reprint Plasminogen activator inhibitor-1 gene 4G/5G polymorphism in Turkish children with asthma and allergic rhinitis
    Ozlem Yilmaz Ozbek
    Department of Pediatric Allergy, Baskent University Faculty of Medicine, Ankara, Turkey
    Allergy Asthma Proc 30:41-6. 2009
    ..Our study suggests that Turkish children with asthma or allergic rhinitis have a higher prevalence of PAI-1 4G allele compared with their healthy peers...
  25. ncbi request reprint Chromosome 22q11.2 microdeletion in a patient with hemophilia A
    Murat Derbent
    Department of Pediatrics, Clinical Genetics Unit, Baskent University Faculty of Medicine, 6, Street Bahcelievler, 06490 Ankara, Turkey
    Ann Genet 47:181-4. 2004
    ..This case underlines that microdeletion of chromosome 22q11.2 should be considered in any patient who exhibits typical clinical features of 22qDS, regardless of whether they have another single-gene disorder...
  26. doi request reprint Peripheral blood picture following mild head trauma in children
    Bulent Alioglu
    Department of Pediatric Hematology, Baskent University Faculty of Medicine, Ankara, Turkey
    Pediatr Int 50:281-3. 2008
    ..The aim of the present study was to investigate changes in peripheral white blood cell, and differential counts following mild head trauma in a pediatric population...
  27. ncbi request reprint The effect of plasminogen activator inhibitor-1 gene 4G/5G polymorphism on glucose and lipid metabolisms in Turkish obese children
    Sibel Tulgar Kinik
    Department of Paediatrics, Division of Paediatric Endocrinology, Baskent University Faculty of Medicine, Ankara, Turkey
    Clin Endocrinol (Oxf) 62:607-10. 2005
    ..In this study, we aimed to elucidate the effect of the PAI-1 4G/5G polymorphism on glucose and lipid metabolism parameters in Turkish obese children...
  28. doi request reprint PAI-1 gene 4G/5G polymorphism, cytokine levels and their relations with metabolic parameters in obese children
    Sibel Tulgar Kinik
    Baskent University Faculty of Medicine, 6 Cadde 70 1, 06490 Bahcelievler, Ankara, Turkey
    Thromb Haemost 99:352-6. 2008
    ..There was no correlation among three cytokines. In conclusion, childhood obesity contributes to higher PAI-1 and TNFalpha and lower TGFbeta levels. Especially PAI-1 and TNFalpha accompany insulin resistance and dyslipidemia...
  29. ncbi request reprint Heterozygous methylenetetrahydrofolate reductase 677C-T gene mutation with mild hyperhomocysteinemia associated with intrauterine iliofemoral artery thrombosis
    Bulent Alioglu
    Baskent University Faculty of Medicine, Department of Pediatric Hematology, Ankara, Turkey
    Blood Coagul Fibrinolysis 17:495-8. 2006
    ..We suggest that methylenetetrahydrofolate reductase gene mutation might be investigated in neonates and their families presenting with thromboembolic disease...
  30. ncbi request reprint Invasive Candida albicans infection mimicking leukemia in a neonate
    Servet Ozkiraz
    Department of Neonatalogy, Baskent University Faculty of Medicine, Ankara, Turkey
    J Matern Fetal Neonatal Med 20:555-7. 2007
    ..Some infections, viral in particular, can mimic clinical signs and/or laboratory findings of congenital leukemia. This is the first documented case of candidemia resembling leukemia...
  31. pmc Genotype-phenotype correlation in combined deficiency of factor V and factor VIII
    Bin Zhang
    Genomic Medicine Institute, Lerner Research Institute, Cleveland Clinic Foundation, OH 44195, USA
    Blood 111:5592-600. 2008
    ..These data suggest that MCFD2 may play a primary role in the export of FV and FVIII from the ER, with the impact of LMAN1 mediated indirectly through its interaction with MCFD2...