G Oktem

Summary

Affiliation: Ege University
Country: Turkey

Publications

  1. pmc Doxorubicin induced nephrotoxicity: protective effect of nicotinamide
    Sule Ayla
    Suleymaniye Woman Health Hospital, 34122 Istanbul, Turkey
    Int J Cell Biol 2011:390238. 2011
  2. doi request reprint Resveratrol attenuates doxorubicin-induced cellular damage by modulating nitric oxide and apoptosis
    Gulperi Oktem
    Ege University Medical Faculty, Department of Histology and Embryology, TR 35100 Izmir, Turkey
    Exp Toxicol Pathol 64:471-9. 2012
  3. doi request reprint Cancer stem cell and embryonic development-associated molecules contribute to prognostic significance in ovarian cancer
    Gulperi Oktem
    Department of Histology and Embryology, Ege University School of Medicine, Izmir, Turkey
    Int J Gynecol Cancer 22:23-9. 2012
  4. ncbi request reprint Role of intercellular communications in breast cancer multicellular tumor spheroids after chemotherapy
    G Oktem
    Department of Histology and Embryology, Ege University School of Medicine, TR 35100 Izmir, Turkey
    Oncol Res 16:225-33. 2006
  5. doi request reprint Determination of nitric oxide synthase activity and apoptosis of germ cells in different obstruction models
    Gulperi Oktem
    Department of Histology and Embryology, Ege University School of Medicine, Izmir, Turkey
    Acta Histochem 111:119-26. 2009
  6. ncbi request reprint Chemotherapy influences inducible nitric oxide synthase (iNOS) and endothelial nitric oxide synthase (eNOS) activity on 3D breast cancer cell line
    G Oktem
    Department of Histology and Embryology, Ege University School of Medicine, TR 35100 Izmir, Turkey
    Oncol Res 16:195-203. 2006
  7. ncbi request reprint Effect of apoptosis and response of extracellular matrix proteins after chemotherapy application on human breast cancer cell spheroids
    G Oktem
    Department of Histology and Embryology, Ege University School of Medicine, TR 35100 Izmir, Turkey
    Oncol Rep 15:335-40. 2006
  8. ncbi request reprint Evaluation of the relationship between inducible nitric oxide synthase (iNOS) activity and effects of melatonin in experimental osteoporosis in the rat
    G Oktem
    Department of Histology and Embryology, School of Medicine, Ege University, Histoloji ve Embriyoloji A D, TR 35100 Izmir, Turkey
    Surg Radiol Anat 28:157-62. 2006
  9. ncbi request reprint Assessment of effects of pinealectomy and exogenous melatonin administration on rat sciatic nerve suture repair: an electrophysiological, electron microscopic, and immunohistochemical study
    M Turgut
    Department of Neurosurgery, Adnan Menderes University School of Medicine, Aydin, Turkey
    Acta Neurochir (Wien) 147:67-77; discussion 77. 2005

Collaborators

Detail Information

Publications9

  1. pmc Doxorubicin induced nephrotoxicity: protective effect of nicotinamide
    Sule Ayla
    Suleymaniye Woman Health Hospital, 34122 Istanbul, Turkey
    Int J Cell Biol 2011:390238. 2011
    ..Conclusions. Pretreatment with NAD protected renal tissues against DXR-induced nephrotoxicity. Preventive effects of NAD on these renal lesions may be via its antioxidant and anti-inflammatory action...
  2. doi request reprint Resveratrol attenuates doxorubicin-induced cellular damage by modulating nitric oxide and apoptosis
    Gulperi Oktem
    Ege University Medical Faculty, Department of Histology and Embryology, TR 35100 Izmir, Turkey
    Exp Toxicol Pathol 64:471-9. 2012
    ..Our data indicate that RES may prevent cellular damage in the early phase of DOX induced toxicity. RES could be used with its beneficial effects during early cellular damage in organ toxicity after DOX treatment in cancer patients...
  3. doi request reprint Cancer stem cell and embryonic development-associated molecules contribute to prognostic significance in ovarian cancer
    Gulperi Oktem
    Department of Histology and Embryology, Ege University School of Medicine, Izmir, Turkey
    Int J Gynecol Cancer 22:23-9. 2012
    ..We hypothesized that similar immunohistochemical expressions between tumor spheroids and patients' samples compared with clinical relevance would give an important clue in patients' prognosis...
  4. ncbi request reprint Role of intercellular communications in breast cancer multicellular tumor spheroids after chemotherapy
    G Oktem
    Department of Histology and Embryology, Ege University School of Medicine, TR 35100 Izmir, Turkey
    Oncol Res 16:225-33. 2006
    ..The MTS model can be used to validate the effects of various combinations or new chemotherapeutic agents as well as documentation of possible mechanisms of new drugs...
  5. doi request reprint Determination of nitric oxide synthase activity and apoptosis of germ cells in different obstruction models
    Gulperi Oktem
    Department of Histology and Embryology, Ege University School of Medicine, Izmir, Turkey
    Acta Histochem 111:119-26. 2009
    ..These cellular changes could enlighten understanding of the interaction between testicular functioning and damage...
  6. ncbi request reprint Chemotherapy influences inducible nitric oxide synthase (iNOS) and endothelial nitric oxide synthase (eNOS) activity on 3D breast cancer cell line
    G Oktem
    Department of Histology and Embryology, Ege University School of Medicine, TR 35100 Izmir, Turkey
    Oncol Res 16:195-203. 2006
    ..Therefore, analyzing the expression of both iNOS and eNOS might be very useful for targeting the treatment of breast carcinoma and obtaining better information on prognosis...
  7. ncbi request reprint Effect of apoptosis and response of extracellular matrix proteins after chemotherapy application on human breast cancer cell spheroids
    G Oktem
    Department of Histology and Embryology, Ege University School of Medicine, TR 35100 Izmir, Turkey
    Oncol Rep 15:335-40. 2006
    ..However, we considered the possibility that there is another control mechanism for the Docetaxel group...
  8. ncbi request reprint Evaluation of the relationship between inducible nitric oxide synthase (iNOS) activity and effects of melatonin in experimental osteoporosis in the rat
    G Oktem
    Department of Histology and Embryology, School of Medicine, Ege University, Histoloji ve Embriyoloji A D, TR 35100 Izmir, Turkey
    Surg Radiol Anat 28:157-62. 2006
    ..In conclusion, melatonin besides its usual use as an antiaging hormone, may also be an effective hormone in treatment of bone changes in estrogen deficiency states...
  9. ncbi request reprint Assessment of effects of pinealectomy and exogenous melatonin administration on rat sciatic nerve suture repair: an electrophysiological, electron microscopic, and immunohistochemical study
    M Turgut
    Department of Neurosurgery, Adnan Menderes University School of Medicine, Aydin, Turkey
    Acta Neurochir (Wien) 147:67-77; discussion 77. 2005
    ..This is the first experimental study investigating the effects of melatonin (MLT) on nerve repair and neuronal regeneration in rat sciatic nerve suture repair...