I Bagcivan

Summary

Affiliation: Cumhuriyet University
Country: Turkey

Publications

  1. ncbi request reprint Investigation of the relaxant effects of pinacidil and cromakalim on the sheep sphincter of Oddi
    Ihsan Bagcivan
    Department of Pharmacology, Cumhuriyet University School of Medicine, Sivas, Turkey
    Pancreatology 6:286-90. 2006
  2. ncbi request reprint Comparative relaxant effects of YC-1 and DEA/NO on the sheep sphincter of Oddi
    Ihsan Bagcivan
    Department of Pharmacology, Cumhuriyet University School of Medicine, Sivas, Turkey
    Pancreatology 6:215-9. 2006
  3. ncbi request reprint Investigation of relaxant effects of propofol on sheep sphincter of Oddi
    Ihsan Bagcivan
    Department of Pharmacology, Cumhuriyet University School of Medicine, Sivas, Turkey
    Pancreatology 7:174-9. 2007
  4. ncbi request reprint Investigation of the relaxant effects of propofol on ovalbumin-induced asthma in guinea pigs
    I Bagcivan
    Cumhuriyet University School of Medicine, Department of Pharmacology, Sivas, Turkey
    Eur J Anaesthesiol 24:796-802. 2007
  5. doi request reprint Effect of hypothyroidism on the purinergic responses of corpus cavernosal smooth muscle in rabbits
    M K Yildirim
    Department of Pharmacology, School of Medicine, Cumhuriyet University, Sivas, Turkey
    Int Urol Nephrol 40:691-9. 2008
  6. ncbi request reprint Effects of intravenous anesthetics on the human radial artery used as a coronary artery bypass graft
    Sinan Gursoy
    Department of Anesthesiology, Cumhuriyet University School of Medicine, Sivas, Turkey
    J Cardiothorac Vasc Anesth 21:41-4. 2007
  7. ncbi request reprint The evaluation of the effects of renal failure on erectile dysfunction in a rabbit model of chronic renal failure
    I Bagcivan
    Department of Urology, Medical Faculty, Cumhuriyet University, Sivas, Turkey
    BJU Int 91:697-701. 2003
  8. ncbi request reprint Relaxation effects of adrenomedullin in isolated rabbit corpus cavernosum smooth muscle
    G Gokce
    Department of Urology, Cumhuriyet University, Sivas, Turkey
    BJU Int 93:859-62. 2004
  9. doi request reprint Investigation of relaxant effects of new agents affecting nitric oxide/cyclic guanosine monophosphate pathway on sheep oddi sphincter
    Bulent Sarac
    Departments of Pharmacology, Cumhuriyet University School of Medicine, Sivas, Turkey
    Pancreas 39:875-8. 2010
  10. ncbi request reprint Effect of L-NAME on decreased ileal muscle contractility induced by peritonitis in rats
    Gokhan Koyluoglu
    Departments of Pediatric Surgery and Pharmacology, Cumhuriyet University, Faculty of Medicine, Sivas, Turkey
    J Pediatr Surg 37:901-5. 2002

Collaborators

Detail Information

Publications47

  1. ncbi request reprint Investigation of the relaxant effects of pinacidil and cromakalim on the sheep sphincter of Oddi
    Ihsan Bagcivan
    Department of Pharmacology, Cumhuriyet University School of Medicine, Sivas, Turkey
    Pancreatology 6:286-90. 2006
    ..This study was designed to investigate the effects of pinacidil and cromakalim, KATP-sensitive channel activators, on sheep sphincters of Oddi (SO)...
  2. ncbi request reprint Comparative relaxant effects of YC-1 and DEA/NO on the sheep sphincter of Oddi
    Ihsan Bagcivan
    Department of Pharmacology, Cumhuriyet University School of Medicine, Sivas, Turkey
    Pancreatology 6:215-9. 2006
    ..This study was designed to compare the effects of YC-1, NO-independent soluble guanylate cyclase (sGC) activator, and DEA/NO, NO-nucleophile adduct, on sheep sphincters of Oddi (SO)...
  3. ncbi request reprint Investigation of relaxant effects of propofol on sheep sphincter of Oddi
    Ihsan Bagcivan
    Department of Pharmacology, Cumhuriyet University School of Medicine, Sivas, Turkey
    Pancreatology 7:174-9. 2007
    ..This study was designed to investigate the effects of propofol on sheep SO...
  4. ncbi request reprint Investigation of the relaxant effects of propofol on ovalbumin-induced asthma in guinea pigs
    I Bagcivan
    Cumhuriyet University School of Medicine, Department of Pharmacology, Sivas, Turkey
    Eur J Anaesthesiol 24:796-802. 2007
    ..The aim of this study was to investigate the possible mechanism of these effects and the effects of propofol on the isolated trachea preparations from control and ovalbumin-sensitized guinea pigs...
  5. doi request reprint Effect of hypothyroidism on the purinergic responses of corpus cavernosal smooth muscle in rabbits
    M K Yildirim
    Department of Pharmacology, School of Medicine, Cumhuriyet University, Sivas, Turkey
    Int Urol Nephrol 40:691-9. 2008
    ..In the present study, we examined purinergic relaxation responses in hypothyroidism in an experimental rabbit model and compared them with controls to evaluate the possible involvement of the purinergic pathway...
  6. ncbi request reprint Effects of intravenous anesthetics on the human radial artery used as a coronary artery bypass graft
    Sinan Gursoy
    Department of Anesthesiology, Cumhuriyet University School of Medicine, Sivas, Turkey
    J Cardiothorac Vasc Anesth 21:41-4. 2007
    ..This study was designed to investigate the direct effects of intravenous anesthetics on the human radial artery (RA)...
  7. ncbi request reprint The evaluation of the effects of renal failure on erectile dysfunction in a rabbit model of chronic renal failure
    I Bagcivan
    Department of Urology, Medical Faculty, Cumhuriyet University, Sivas, Turkey
    BJU Int 91:697-701. 2003
    ..To determine whether chronic renal failure (CRF) reduces nitrergic relaxant responses in a rabbit model...
  8. ncbi request reprint Relaxation effects of adrenomedullin in isolated rabbit corpus cavernosum smooth muscle
    G Gokce
    Department of Urology, Cumhuriyet University, Sivas, Turkey
    BJU Int 93:859-62. 2004
    ....
  9. doi request reprint Investigation of relaxant effects of new agents affecting nitric oxide/cyclic guanosine monophosphate pathway on sheep oddi sphincter
    Bulent Sarac
    Departments of Pharmacology, Cumhuriyet University School of Medicine, Sivas, Turkey
    Pancreas 39:875-8. 2010
    ..We aimed to investigate the effects of new NO/cyclic guanosine monophosphate (cGMP) pathway-affecting agents at the sheep sphincter of Oddi (SO) in vitro...
  10. ncbi request reprint Effect of L-NAME on decreased ileal muscle contractility induced by peritonitis in rats
    Gokhan Koyluoglu
    Departments of Pediatric Surgery and Pharmacology, Cumhuriyet University, Faculty of Medicine, Sivas, Turkey
    J Pediatr Surg 37:901-5. 2002
    ....
  11. ncbi request reprint Relaxation induced by omeprazole does not change in diabetic rabbit corpus cavernosum
    S Ayan
    Department of Urology, School of Medicine, Cumhuriyet University, Sivas, Turkey
    BJU Int 87:265-8. 2001
    ..CONCLUSION: The relaxant effect of omeprazole in corpus cavernosum was not affected by diabetes, in which neurogenic and endothelium-mediated relaxations were impaired...
  12. doi request reprint Effect of nitric oxide/cyclic guanosine mono-phosphate pathway on gallbladder relaxant response in bile duct-ligated guinea pigs
    C Aydin
    Department of General Surgery, Cumhuriyet University School of Medicine, Sivas, Turkey
    Eur Surg Res 42:189-94. 2009
    ..The aim of this study was to determine whether the NO/cyclic guanosine monophosphate pathway plays a role in gallbladder relaxant response after CBDL...
  13. pmc Altered spontaneous contractions of the ileum by anesthetic agents in rats exposed to peritonitis
    Cengiz Aydin
    Department of General Surgery, Cumhuriyet University School of Medicine, Sivas, Turkey
    World J Gastroenterol 15:1620-4. 2009
    ..To investigate in vitro effects of propofol, midazolam and dexmedetomidine, which are commonly used anaesthesic or sedatives, on spontaneous contractions of the ileum both in normal rats and those exposed to hyperdynamic peritonitis...
  14. ncbi request reprint The role of K(+) channels on the inhibitor effect of sevoflurane in pregnant rat myometrium
    Haluk Kafali
    Department of Anesthesiology, Cumhuriyet University School of Medicine, Sivas, Turkey
    Anesth Analg 94:174-8, table of contents. 2002
    ..Such inhibition was reduced by TEA. The inhibition of myometrial smooth muscle induced by sevoflurane seems to be mediated, at least in part, via activation of Ca(2+)-activated K(+) channels, because inhibition was reduced by TEA...
  15. ncbi request reprint Investigation of the mechanism of nicotine induced relaxation in rabbit corpus cavernosum in vitro
    Ihsan Bagcivan
    Department of Pharmacology, Cumhuriyet University, Sivas, Turkey
    Urol Res 32:209-12. 2004
    ..Further work is needed to determine the cellular mechanism(s) of the action by which nicotine acts on corporal smooth muscle...
  16. ncbi request reprint Effect of hypothyroidism on the nitrergic relaxant responses of corpus cavernosal smooth muscle in rabbits
    Bulent Sarac
    Department of Pharmacology, School of Medicine, Cumhuriyet University, Silvas, Turkey
    Int J Urol 13:58-63. 2006
    ..However, several recent studies have reported evidence of hormonal abnormalities in 25-35% of impotent men. Hypothyroidism has been reported to occur in 6% of impotent men...
  17. ncbi request reprint Evaluation of urinary bladder function after acute spinal cord injury: an experimental study
    Zekeriya Oztemur
    Department of Orthopedics and Traumatology, Cumhuriyet University, Sivas, Turkey
    Eklem Hastalik Cerrahisi 21:110-5. 2010
    ..The aim of this study was to evaluate the efficacy of early surgical decompression of acute spinal cord injury through the evaluation of urinary bladder function in rabbits...
  18. doi request reprint Rho-kinase inhibitors Y-27632 and fasudil prevent agonist-induced vasospasm in human radial artery
    Olcay Murat Disli
    Department of Cardiovascular Surgery, Cumhuriyet University School of Medicine, Sivas 58140, Turkey
    Can J Physiol Pharmacol 87:595-601. 2009
    ..Rho-kinase inhibitors may have an important role in preventing vasospasm in arterial grafts used for coronary artery surgery...
  19. ncbi request reprint Investigation of the vasorelaxant effects of 3-(5'-hydroxymethyl-2'-furyl)-1-benzyl indazole (YC-1) and diethylamine/nitric oxide (DEA/NO) on the human radial artery used as coronary bypass graft
    Ocal Berkan
    Department of Cardiovascular Surgery, Cumhuriyet University School of Medicine, 58140 Sivas, Turkey
    Can J Physiol Pharmacol 85:521-6. 2007
    ..YC-1 and DEA/NO may be effective as vasodilator for the short-term treatment of perioperative spasm of coronary bypass grafts...
  20. ncbi request reprint Alterations in spontaneous contractions of rat ileum and jejunum after peritonitis
    Gokhan Koyluoglu
    Cumhuriyet University, Faculty of Medicine, Department of Pediatric Surgery, 58140 Sivas, Turkey
    Eur J Pharmacol 580:250-5. 2008
    ..In conclusion, peritonitis induces the decrease in the amplitude and frequency of spontaneous contractions of ileum and jejunum that can be attributed to the rise of nitric oxide synthase and cyclooxygenase isoforms levels...
  21. doi request reprint Effects of NO/L-arginine pathway on gallbladder contractility in bile duct ligated guinea pigs
    Sinan Soylu
    Department of General Surgery, Cumhuriyet University School of Medicine, Sivas, Turkey
    J Surg Res 155:70-6. 2009
    ..The aim of this study was to determine whether the nitric oxide-L-arginine pathway plays a role in the inflammatory process and abnormal gallbladder contractility that occur after CBDL...
  22. pmc Lack of nitrate tolerance in isosorbid dinitrate- and sodium nitroprusside-induced relaxation of rabbit internal anal sphincter
    Ayhan Koyuncu
    Department of General Surgery, School of Medicine, Cumhuriyet University, Sivas, Turkey
    World J Gastroenterol 14:4667-71. 2008
    ..To investigate the tolerance development against the relaxant effect of nitric oxide donating drug isosorbide dinitrate (ISDN) and sodium nitroprusside (SNP) in internal anal sphincter (IAS) smooth muscle...
  23. ncbi request reprint In vitro effects of intravenous anesthetics on the sphincter of Oddi strips of sheep
    Mustafa Turan
    Department of General Surgery, Faculty of Medicine, Cumhuriyet University, Sivas, Turkey
    Pancreatology 5:215-9. 2005
    ..This study was designed to investigate the direct effects of some intravenous anesthetics on SO in sheep...
  24. ncbi request reprint Comparative relaxant effects of YC-1 and DETA/NO on spontaneous contractions and the levels of cGMP of isolated pregnant rat myometrium
    Nihal Demirkoprulu
    Department of Obstetrics and Gynecology, Cumhuriyet University School of Medicine, 58140, Sivas, Turkey
    Eur J Pharmacol 517:240-5. 2005
    ....
  25. ncbi request reprint Effect of peritonitis on gallbladder smooth muscle contractility in guinea pigs
    Tijen Temiz Kaya
    Department of Pharmacology, Faculty of Medicine, Cumhuriyet University, 58030 Sivas, Turkey
    J Surg Res 120:219-24. 2004
    ..The aim of this study was to determine the effect of peritonitis on the contraction and relaxation responses to different agonists in gallbladder smooth muscle in guinea pig...
  26. ncbi request reprint Relaxation effects of adrenomedullin in carbachol-precontracted rabbit internal anal sphincter
    Ayhan Koyuncu
    Department of General Surgery, School of Medicine, Cumhuriyet University, Sivas, Turkey
    J Gastroenterol 38:460-4. 2003
    ..In this in vitro study, we aimed to investigate whether adrenomedullin had a relaxant effect on isolated rabbit internal anal sphincter, and the possible involvement of nitric oxide, prostaglandins, and K(+) channels...
  27. ncbi request reprint Interactive effect of sevoflurane with isradipine or indomethacin on spontaneous contractile activity of isolated pregnant rat myometrium
    S Gursoy
    Department of Anesthesiology, Cumhuriyet University School of Medicine, Sivas, Turkey
    Int J Obstet Anesth 13:234-8. 2004
    ..05). Blockade of calcium channels in myometrial smooth muscle may increase the inhibitor effect of sevoflurane. Further work is needed to determine the cellular mechanism(s) of this interaction...
  28. ncbi request reprint Vasorelaxant effect of opioid analgesics on the isolated human radial artery
    S Gursoy
    Department of Anesthesiology, Cumhuriyet University School of Medicine, Sivas, Turkey
    Eur J Anaesthesiol 23:496-500. 2006
    ..Opioid analgesics are commonly used in the perioperative course of cardiac surgical procedures. Therefore, we investigated the direct effects of morphine, meperidine, fentanyl and remifentanil on the human radial artery...
  29. pmc Nifedipine enhances the relaxant effects of cyclo-oxygenase inhibitors on the bovine ciliary muscle
    Mustafa Toker
    Department of Ophthalmology, Cumhuriyet University School of Medicine, Sivas, Turkey
    J Ocul Pharmacol Ther 24:537-41. 2008
    ....
  30. doi request reprint The effect of sildenafil on the altered thoracic aorta smooth muscle responses in rat pre-eclampsia model
    Nergiz Hacer Turgut
    Department of Pharmacology, Institute of Health Sciences, Cumhuriyet University, Sivas, Turkey
    Eur J Pharmacol 589:180-7. 2008
    ..The results in this study show that in pre-eclampsia; PDE5 inhibitors enhance endothelial function and may be used for protection. Further studies are needed to clear the efficiency and safety of PDE5 inhibitors...
  31. doi request reprint Effects of fluoxetine and LY 367265 on tolerance to the analgesic effect of morphine in rats
    Ercan Ozdemir
    Department of Physiology, Cumhuriyet University School of Medicine, Sivas, Turkey
    Acta Physiol Hung 98:205-13. 2011
    ..In conclusion, we observed that co-injection of morphine with fluoxetine and LY 367265 increased the analgesic effects of morphine and delayed development of tolerance to morphine analgesia...
  32. ncbi request reprint Hydrogen-potassium ATPase inhibitors induce relaxation on rabbit prostatic strips in vitro
    Ihsan Bagcivan
    Department of Pharmacology, Cumhuriyet University, School of Medicine, Sivas, Turkey
    Int J Urol 9:641-4; discussion 645. 2002
    ..To determine the relaxant effect of omeprazole and lansaprazole, hydrogen-potassium (H+-K+) ATPase inhibitors, on rabbit prostatic tissue in vitro...
  33. ncbi request reprint Investigation of the mechanism of nicotine-induced relaxation on the sheep sphincter of Oddi
    Ihsan Bagcivan
    Department of Pharmacology, Cumhuriyet University School of Medicine, Sivas, Turkey
    Can J Physiol Pharmacol 82:935-9. 2004
    ..Potentiation of the nicotine-induced relaxation by bupivacain indicates that blockade of sodium channels may play a role in this relaxation...
  34. ncbi request reprint Comparison of effects of cyclooxygenase inhibitors on myometrial contraction and constriction of ductus arteriosus in rats
    Baris Karadas
    Department of Pharmacology, Cumhuriyet University School of Medicine, 58140, Sivas, Turkey
    Eur J Pharmacol 485:289-98. 2004
    ..05). These data demonstrate that DFU, a specific cyclooxygenase-2 inhibitor, could be considered as a new therapeutic agent for preterm labour. However, careful attention should be given to constriction of the fetal ductus arteriosus...
  35. ncbi request reprint Enhancement of EFS-induced contractions, by agmatine, in guinea pig gallbladder smooth muscle strips
    Sahin Yildirim
    Department of Pharmacology, Cumhuriyet University Medical School, 58140, Sivas, Turkey
    J Gastroenterol 40:498-503. 2005
    ..The aim of this study was to investigate the role of agmatine, a ligand for alpha 2-adrenoceptors and imidazoline binding sites, in the cholinergic motor activity of guinea pig gallbladder smooth muscle...
  36. ncbi request reprint Do antibiotics contribute to postoperative ileus? Contractile responses of ileum smooth muscle in Guinea pigs to long-term parenteral ceftriaxone and ampicillin
    Canan Ceran
    Departments of Pediatric Surgery and Department of Pharmacology, Cumhuriyet University School of Medicine, Sivas, Turkey
    ANZ J Surg 76:1023-6. 2006
    ..Hoffman-La Roche, Kaiseraugst, Switzerland) or ampicillin (Ampisina; Mustafa Nevzat IlaƧ Sanayii AS, Istanbul, Turkey)...
  37. ncbi request reprint Mechanism of relaxation induced by nicotine in normal and ovalbumin-sensitized guinea-pig trachea
    Omer Cevit
    Department of Pediatry, Cumhuriyet University School of Medicine, 58140 Sivas, Turkey
    Eur J Pharmacol 567:149-54. 2007
    ..The decreased relaxation response to nicotine in ovalbumin sensitized guinea-pigs trachea may be due to impaired production and/or liberation of NO...
  38. ncbi request reprint Additive interaction of intraperitoneal dexmedetomidine and topical nimesulide, celecoxib, and DFU for antinociception
    Baris Karadas
    Department of Pharmacology, Cumhuriyet University School of Medicine, 58140 Sivas, Turkey
    Eur J Pharmacol 556:62-8. 2007
    ..These observations are significant for physicians to combine selective COX-2 inhibitors and dexmedetomidine in the management of pain...
  39. ncbi request reprint Effect of chronic renal failure on the purinergic responses of corpus cavernosal smooth muscle in rabbits
    H Kilicarslan
    Department of Urology, Medical Faculty of Cumhuriyet University, Sivas, Turkey
    BJU Int 90:596-600. 2002
    ..To examine purinergic relaxation responses in chronic renal failure (CRF) in an experimental rabbit model, and thus evaluate the possible involvement of the purinergic system in erectile dysfunction with CRF...
  40. ncbi request reprint Comparison of effects of formoterol and BRL 37344 on isolated term-pregnant rat myometrial strips in vitro
    Nazan Yurtcu
    Department of Obstetrics and Gynecology, Cumhuriyet University School of Medicine, 58140 Sivas, Turkey
    Eur J Pharmacol 530:263-9. 2006
    ..05). Formoterol and BRL 37344 decreased amplitude of myometrial contractions with similar potency, but efficacy of formoterol was better than BRL 37344...
  41. doi request reprint Investigation of the relaxant effects of pancuronium, rocuronium, vecuronium and mivacurium on rat thoracic aorta
    Sinan Gursoy
    Department of Anaesthesiology, Cumhuriyet University School of Medicine, Sivas, Turkey
    Eur J Anaesthesiol 26:155-9. 2009
    ..We aimed to investigate the relaxant effects and possible underlying mechanisms of these agents on isolated rat thoracic aorta...
  42. ncbi request reprint Effects of formoterol and BRL 37344 on human umbilical arteries in vitro in normotensive and pre-eclamptic pregnancy
    Baris Karadas
    Department of Pharmacology, Izmir Ataturk Training and Research Hospital, 35360 Izmir, Turkey
    Vascul Pharmacol 46:360-6. 2007
    ....
  43. ncbi request reprint Effect of hypothyroidism on the NO/cGMP pathway of corpus cavernosum in rabbits
    Hakan Kilicarslan
    Department of Urology, Faculty of Medicine, Uludag University, Bursa, Turkey
    J Sex Med 3:830-7. 2006
    ..Hypothyroidism has been reported to occur in 6% of impotent men. There is some evidence suggesting that hypothyroidism may be a cause of impotence...
  44. doi request reprint Changes in spontaneous contractions of rat ileum by aflatoxin in vitro
    Nevcihan Gursoy
    Faculty of Engineering, Department of Food Engineering, Cumhuriyet University, 58140 Sivas, Turkey
    Food Chem Toxicol 46:2124-7. 2008
    ..But the decrease of amplitude was more than the frequency in the presence of these antagonists. In conclusion, these findings of aflatoxin on isolated rat ileum may explain their acute gastrointestinal effects in humans and animals...
  45. ncbi request reprint Alterations in spontaneous contractions of rat proximal and distal colon after peritonitis
    Turan Yildiz
    Department of Pediatric Surgery, Cumhuriyet University, Faculty of Medicine, 58140 Sivas, Turkey
    J Pediatr Surg 42:1215-20. 2007
    ..The aim of this study was to investigate the effect of peritonitis on spontaneous contractions of distal and proximal colon smooth muscle isolated from rats...
  46. doi request reprint Investigation of acute effects of aflatoxin on rat proximal and distal colon spontaneous contractions
    Nevcihan Gursoy
    Cumhuriyet University Faculty of Engineering, Department of Food Engineering, 58140 Sivas, Turkey
    Food Chem Toxicol 46:2876-80. 2008
    ..These findings of aflatoxin on isolated rat proximal and distal colon may explain their acute gastrointestinal effects in humans and animals...
  47. ncbi request reprint The effect of chronic renal failure on phosphodiesterase inhibitor-induced relaxation responses in rabbit cavernosal strips
    Hakan Kilicarslan
    Department of Urology, Faculty of Medicine, University of Cumhuriyet, 58140 Sivas, Turkey
    Eur J Pharmacol 462:155-60. 2003
    ..These results suggest that the decreased production or availability of endogenous nitric oxide in chronic renal failure animals leads to decreased efficacy of phosphodiesterase 5 inhibitors to induce relaxation...