Research Topics
Genomes and GenesSpecies | Semra PaydasSummaryAffiliation: Cukurova University Country: Turkey Publications
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Detail Information
Publications
The expression of survivin and Ki-67 in meningiomas: correlation with grade and clinical outcomeFazilet Kayaselcuk
Department of Pathology, Faculty of Medicine, Adana Teaching and Medical Research Center, Baskent University, Turkey
J Neurooncol 67:209-14. 2004....
Strong cross-talk between angiogenesis and EBV: do we need different treatment approaches in lymphoma cases with EBV and/or high angiogenic capacitySemra Paydas
Faculty of Medicine, Department of Oncology, Cukurova University, Adana, Turkey
Med Oncol 29:2159-65. 2012..Due to the strong cross-talk between angiogenesis and viral lymphomagenesis, this association was reviewed in this study...
Fludarabine-induced hemolytic anemia: successful treatment by rituximabSemra Paydas
Department of Oncology, Faculty of Medicine, Cukurova University, Adana, Turkey
Hematol J 5:81-3. 2004..Here, a case with CLL and severe autoimmune hemolytic anemia associated with fludarabine and successful treatment by rituximab has been reported...
Granulocytic sarcoma: 32 cases and review of the literatureSemra Paydas
Department of Oncology, Cukurova University Faculty of Medicine, Adana, Turkey
Leuk Lymphoma 47:2527-41. 2006..The critical factors for detecting this interesting tumor are to be aware of this disease, cooperation between clinician and pathologist and the application of special stains to detect the myeloid origin...
Detection of hepatitis C virus RNA in paraffin-embedded tissues from patients with non-Hodgkin's lymphomaSemra Paydas
Department of Oncology, Cukurova University Faculty of Medicine, 01330 Balcali, Adana, Turkey
Am J Hematol 76:252-7. 2004..Detection of anti-HCV antibody in only three cases may be associated with undetectable levels of antibodies due to the immune deficiency in cases with NHL...
PRAME mRNA levels in cases with chronic leukemia: Clinical importance and review of the literatureSemra Paydas
Cukurova University, Faculty of Medicine, Department of Oncology, 01330 Adana, Turkey
Leuk Res 31:365-9. 2007..PRAME mRNA changes may be detected during the progression of these disorders and/or after therapy. PRAME mRNA may be a useful marker to detect the minimal residual disease (MRD) and to determine the response to therapy in CLs...
Cyclooxygenase-2 expression in non-Hodgkin's lymphomasSemra Paydas
Department of Oncology, Faculty of Medicine, Cukurova University, Adana, Turkey
Leuk Lymphoma 48:389-95. 2007..In conclusion Cox-2 expression is seen about 60% of the cases with NHL and is associated with aggressive morphology...
Thrombospondin-1 (TSP-1) and Survivin (S) expression in non-Hogkin's lymphomasSemra Paydas
Department of Oncology, Cukurova University Faculty of Medicine, Turkey
Leuk Res 32:243-50. 2008..2428). In conclusion, S and TSP-1 expressions were detected in 53 and 17.5% of the cases with NHL, and are associated with aggressive histology and shorter OS...
Anti-HCV and HCV-RNA prevalence and clinical correlations in cases with non-Hodgkin's lymphomaSemra Paydas
Department of Oncology, Cukurova University Faculty of Medicine, Adana, Turkey
Am J Hematol 74:89-93. 2003..Simultaneous detection of anti-HCV and HCV-RNA will be more informative in this population...
Granulomatous orchitis mimicking Hodgkin's lymphoma relapseSemra Paydas
Department of Oncology, Faculty of Medicine, Cukurova University, Adana, Turkey
Hematol J 4:370-1. 2003
Prognostic significance of EBV-LMP1 and VEGF-A expressions in non-Hodgkin's lymphomasSemra Paydas
Department of Oncology, Cukurova University, Faculty of Medicine, Adana, Turkey
Leuk Res 32:1424-30. 2008..The viral latent protein LMP1, may play a role by inducing expression of angiogenic factors In this study EBV-LMP1 and VEGF-A expressions have been studied in cases with NHL and prognostic significance of these has been evaluated...
Survivin and aven: two distinct antiapoptotic signals in acute leukemiasS Paydas
Department of Oncology, Cukurova University Faculty of Medicine, Adana, Turkey
Ann Oncol 14:1045-50. 2003..Real-time quantitative PCR was used and survivin and aven were detected at the messenger (m)RNA level...
The prognostic significance of VEGF-C and VEGF-A in non-Hodgkin lymphomasSemra Paydas
Faculty of Medicine, Department of Oncology, Cukurova University, Adana, Turkey
Leuk Lymphoma 50:366-73. 2009....
Prognostic [corrected] significance of angiogenic/lymphangiogenic, anti-apoptotic, inflammatory and viral factors in 88 cases with diffuse large B cell lymphoma and review of the literatureSemra Paydas
Department of Oncology, Cukurova University Faculty of Medicine, 01330 Adana, Turkey
Leuk Res 33:1627-35. 2009....
Serous retinal detachment in a case with chronic lymphocytic leukemia: no response to systemic and local treatmentSemra Paydas
Department of Oncology, Faculty of Medicine, Cukurova University, Balcali, Adana 01330, Turkey
Leuk Res 27:557-9. 2003..Here we reported a case with chronic lymphocytic leukemia (CLL) presenting with SRD and discussed the clinical importance and therapeutic options...
Vasculitis associated with all trans retinoic acid (ATRA) in a case with acute promyelocytic leukemiaSemra Paydas
Department of Oncology, Cukurova University, Faculty of Medicine, Cukurova University Adana, Turkey
Leuk Lymphoma 44:547-8. 2003..Here, we report vasculitis in a case with APL treated with ATRA and review the literature...
PRAME mRNA levels in cases with acute leukemia: clinical importance and future prospectsSemra Paydas
Department of Oncology, Cukurova University Faculty of Medicine, Adana, Turkey
Am J Hematol 79:257-61. 2005....
Dramatic response with capecitabine after cranial radiation to the brain parenchymal and leptomeningeal metastases from lung cancerSemra Paydas
Cukurova University, Faculty of Medicine, Department of Oncology, Turkey
Eur J Intern Med 20:96-9. 2009..Here we reported a case with lung cancer metastatic to the brain and we discussed the good response to capecitabine after cranial radiotherapy (C)...
Survivin and EPR-1 expression in acute leukemias: prognostic significance and review of the literatureOzgur Akin Oto
Cukurova University, Faculty of Medicine, Department of Oncology, Adana, Turkey
Leuk Res 31:1495-501. 2007..S negativity and E positivity show good clinical outcome in acute leukemias. E expression is important due to its property of the possible natural anti-sense of the S...
IDA-FLAG regimen for the therapy of primary refractory and relapse acute leukemia: a single-center experienceSinan Yavuz
Division of Oncology, Department of Internal Medicine, School of Medicine, Cukurova University, Balcali Adana, Turkey
Am J Ther 13:389-93. 2006..High efficacy and a low-toxicity profile are preferable properties of this regimen, and this regimen has been found to be useful for cytoreduction, especially in candidates for allo-SCT...
Prognostic significance of microvessel density and vascular endothelial growth factor (VEGF) expression in non-Hodgkin's lymphomaBurhan Hazar
Department of Oncology, Mersin University School of Medicine, 33079, Mersin, Turkey
Leuk Lymphoma 44:2089-93. 2003..The combination of anti-angiogenic drugs with conventional anti-neoplastic treatment will probably be used in the future. Larger series of patients are needed to determine the prognostic value of angiogenesis in NHL...
Extramedullary relapse in the pleura in acute promyelocytic leukemiaUmut Disel
Department of Oncology, Cukurova University Faculty of Medicine, Adana, Turkey
Leuk Lymphoma 44:189-91. 2003..Recently, we have encountered an EM relapse in the pleura in a case with APL receiving an ATRA containing regimen. This case is reported and the relevant literature is reviewed...
Granulomatous reaction after chemotherapy for Hodgkin's diseaseSemra Paydas
Department of Oncology, Faculty of Medicine, Cukurova University, 01330 Balcali, Adana, Turkey
Leuk Res 26:967-70. 2002
Gravin gene expression in acute leukaemias: clinical importance and review of the literatureMustafa Yildirim
Department of Oncology, Cukurova University Faculty of Medicine, Cukurova University, Adana, Turkey
Leuk Lymphoma 48:1167-72. 2007..Because of paradoxical results, there is a need for more studies exploring gravin isoforms and other related gene expressions...
VEGF-C expression in breast cancer: clinical importanceSinan Yavuz
Department of Oncology, Faculty of Medicine, Cukurova University, Balcali, Adana, Turkey
Adv Ther 22:368-80. 2005..To determine the relationship among angiogenesis, lymphangiogenesis, and prognosis, more standardized methods to demonstrate the angiogenesis, and prospective studies to cover a larger, more homogenous patient population are needed...
Hepatitis B virus reactivation during fludarabine therapy in non-Hodgkin's lymphomaSinan Yavuz
Department of Oncology, Faculty of Medicine, Cukurova University, Balcali, Adana, Turkey
Leuk Lymphoma 44:1249-50. 2003
Bone marrow necrosis: clinicopathologic analysis of 20 cases and review of the literatureSemra Paydas
Department of Oncology, Cukurova University Faculty of Medicine, Balcal, Adana, Turkey
Am J Hematol 70:300-5. 2002..In conclusion malignancy is the most common cause of BMN but some nonmalignant conditions such as tuberculosis and APS may be the underlying cause of BMN...
Granulocytic sarcoma of the heart: extramedullary relapse of acute myeloblastic leukemia after allogeneic stem cell transplantation successfully treated by chemotherapy aloneIsmail Oguz Kara
Department of Medical Oncology, Cukurova University Faculty of Medicine, Yuregir, Adana, Turkey
Leuk Lymphoma 46:1081-4. 2005..The involvement of the heart with GS is very rare and this is the first case of extramedullary disease in the heart after allogeneic transplantation. Here we present the case history and related literature has been reviewed...
Bilateral choroidal infiltration from indolent non-Hodgkin's lymphoma: a rapid course with poor prognosisAltan A Ozcan
Department of Ophthalmology, Faculty of Medicine, Cukurova University, Adana, Turkey
Leuk Lymphoma 46:615-7. 2005..Radiotherapy did not provide local control and preservation of the vision. Non-Hodgkin's lymphoma can infiltrate to the choroid and radiotherapy may not be efffective in every case...
Vascular endothelial growth factor (VEGF) expression in plasmacytomaSemra Paydas
Department of Oncology, Faculty of Medicine, Cukurova University, Adana, Turkey
Leuk Lymphoma 43:139-43. 2002..Increased expression of VEGF was seen in plasmacytomas, and additional studies are needed to determine whether this translates to increased microvasculature or increased risk of progression to myeloma...
Ovarian granulocytic sarcomaSinan Yavuz
Cukurova University, Faculty of Medicine, Department of Oncology, Balcali, Adana, Turkey
Leuk Lymphoma 45:183-5. 2004..Ovarian granulocytic sarcoma is a rare entity in daily practice. Here we report an ovarian granulocytic sarcoma, initially diagnosed as NHL, and review the literature...
Glomerular disease in patients with malignant disease: four cases and review of literatureSaime Paydas
Department of Nephrology, Faculty of Medicine, Cukurova University, Adana, Turkey
Ren Fail 27:1-6. 2005..Here we report four cases with malignant diseases and accompanying glomerular injury and review the literature...
Comparative analysis of CA 125, ferritin, beta-2 microglobulin, lactic dehydrogenase levels in serum and peritoneal fluid in patients with ovarian neoplasiaUmran Kucukgoz Gulec
Department of Obstetrics and Gynecology, Faculty of Medicine, Cukurova University, Adana, Turkey
Med Oncol 29:2937-43. 2012..3 and 85%, respectively with the cut-off value: 2.3 mg/l. This study results indicates that especially PF β2 M and ferritin levels may be valuable for diagnosis of malignant ascites in patients with ovarian neoplasms...
Amphotericin B deoxycholate (d-AMB) use in cases with febrile neutropenia and fungal infections: lower toxicity with suitable premedicationOzgur Akin Oto
Department of Oncology, Faculty of Medicine, Cukurova University, Adana, Turkey
Mycoses 50:135-9. 2007..With these findings, we can conclude that d-AMB is a tolerable, low cost drug which can be safely used provided there is suitable premedication and monitoring of blood urea nitrogen, serum potassium and magnesium levels...
Adenosine deaminase activity in patients with ovarian neoplasmsIbrahim Ferhat Urunsak
Department of Obstetrics and Gynecology, Cukurova University, Adana, Turkey
Arch Gynecol Obstet 286:155-9. 2012..The aim of this study was to investigate the serum and peritoneal fluid adenosine deaminase (ADA) activity in patients with benign and malignant ovarian neoplasms...
Flow cytometric evaluation of bone marrow plasma cells using CD19, CD45, CD56, CD38, and CD138 and correlation with bone marrow infiltration ratio in multiple myeloma patientsIsmail O Kara
Department of Medical Oncology, Cukurova University, Faculty of Medicine, Balcali Hospital, Yuregir 01330, Adana, Turkey
Saudi Med J 25:1587-92. 2004..To examine the co-expression of CD19, CD45, CD38, CD56, and CD138 molecules in plasma cells of bone marrow (BM) aspirates and their relation with BM infiltration, and treatment in patients with multiple myeloma by flow cytometry...
Different glomerulopathies accompanying non-small-cell lung cancerSaime Paydas
Department of Internal Medicine, Cukurova University, Faculty of Medicine, 01330 Adana, Turkey
Mt Sinai J Med 72:279-81. 2005..Other glomerulopathies are seldom reported. We report two cases presenting with non-small-cell lung cancer, acute renal failure and nephrotic syndrome secondary to membranoproliferative glomerulonephritis and amyloidosis...
Antioxidant enzyme levels in cases with gastrointesinal cancerYalcin Kekec
Department of General Surgery, Faculty of Medicine, Cukurova University, Adana, Turkey
Eur J Intern Med 20:403-6. 2009..The aim is to evaluate the antioxidant enzyme levels in tumoral tissues and accompanying normal tissues in gastrointestinal cancer; and compare the colorectal cancer (CRC) with gastric cancer (GC)...
Castleman-like reaction due to toxic substance ingestionSemra Paydas
Cukurova University, Faculty of Medicine, Department of Medical Oncology, Turkey
Eur J Intern Med 20:328-30. 2009..Generally diagnosis is not difficult for an experienced pathologist. However, not usually, some histopathological entities or tissue reactions may mimic CD. Here CD-like reaction due to toxic substance ingestion has been presented...
Secondary malignancy after imatinib therapy: eight cases and review of the literatureBerna Bozkurt Duman
Department of Medical Oncology, Faculty of Medicine, Cukurova University, Adana, Turkey
Leuk Lymphoma 53:1706-8. 2012..Here we report eight cases with neoplasias that developed during imatinib therapy and review secondary malignant disorders occurring during/after imatinib treatment...
Capecitabine-induced hypertriglyceridemia and hyperglycemia: two casesBerna Bozkurt Duman
Cukurova University Medical Faculty Departments of Medical Oncology, Balcali Hospital, Adana, Turkey
Pharmacology 90:212-5. 2012..Capecitabine was discountinued and antilipemic treatments were given and both cases are in follow-up with normal lipid levels. This report describes CI-HTG and possible pathogenetic mechanisms and the literature is reviewed...
Chronic myeloid leukemia in a patient with colon adenocarcinomaYuksel Gokel
Department of Emergency, Faculty of Medicine, Cukurova University, Adana, Turkey
Haematologia (Budap) 32:501-3. 2002..Here we reported a case with colon adenocarcinoma and later developing CML which is not reported so far in according to our knowledge...
The value of 18F-fluorodeoxyglucose positron emission tomography/computed tomography in carcinoma of an unknown primary: diagnosis and follow-upZeynep Yapar
Department of Nuclear Medicine, Cukurova University Faculty of Medicine, Turkey
Nucl Med Commun 31:59-66. 2010..18F-fluorodeoxyglucose positron emission tomography/computed tomography (FDG PET/CT) has provided new insights in the diagnosis, staging, and follow-up of oncological patients...
Motor neuron disease associated with multiple myelomaFiliz Koc
Department of Neurology, Cukurova University, Faculty of Medical, Adana, Turkey
Int J Neurosci 118:337-41. 2008..This article reports a case of a 75-year-old male with MM and MND. Interestingly, the patient was in complete remission for MM when he was diagnosed as MND and he died due to progressive MND...
Sickle cell anemia and hematological neoplasiasSemra Paydas
Faculty of Medicine, Department of Oncology, Cukurova University, Balcali, Adana, Turkey
Leuk Lymphoma 43:1431-4. 2002..A standard therapeutic approach without any additional toxicity was relevant in all cases. Detailed clinical presentation and outcome of these five cases are documented here and the literature has been reviewed...
A general aspect on soft-tissue sarcoma and c-kit expression in primitive neuroectodermal tumor and Ewing's sarcoma. Is there any role in disease process?Ismail O Kara
Department of Medical Oncology, Faculty of Medicine, Cukurova University, 01330, Adana, Turkey
Saudi Med J 26:1190-6. 2005..Our aim is to investigate the c-kit expression in ES and PNET and also to assessed if c-kit has any role in disease process...
Helicobacter pylori in the etiology of cholesterol gallstonesBahri Abayli
Division of Gastroenterology, Department of Internal Medicine, Faculty of Medicine, University of Cukurova, Adana, Turkey
J Clin Gastroenterol 39:134-7. 2005..pylori in gallstones by microbiologic cultivation, histopathologic staining, and polymerase chain reaction (PCR)...
Cutaneous leishmaniasis: evaluation by polymerase chain reaction in the Cukurova region of TurkeyMelek Ergin
Cukurova University Medical School, Department of Pathology, Balcali Adana, Turkey
J Parasitol 91:1208-11. 2005..9%); the second extraction of DNA was positive in 47 of 54 cases (87%). PCR was negative in all of the nonleishmaniasis cases. The PCR-based method appears to be a useful diagnostic approach for identification of suspected cases of CL...
Nonsynergistic effects of trimetazidine and selenium combination therapy on renal ischemic-reperfusion injury in ratsIbrahim Karayaylali
Department of Nephrology, Cukurova University, Medical School, Adana, Turkey
Adv Ther 21:47-60. 2004..Moreover, these treatments prevent histologic findings of postischemic-perfusion renal injury...
Primary peritracheal schwannoma: report of a caseSeyda Erdogan
Department of Pathology, Cukurova University, School of Medicine, 0130 Balcali, Adana, Turkey
Surg Today 34:444-6. 2004..Although rare, primary tracheal schwannoma should be considered in the differential diagnosis of sudden respiratory distress of unknown origin...
Expression of COX-2, PCNA, Ki-67 and p53 in gastrointestinal stromal tumors and its relationship with histopathological parametersDerya Gumurdulu
Department of Pathology of Affiliated Hospital, Faculty of Medicine, Cukurova University, Adana 01330, Turkey
World J Gastroenterol 13:426-31. 2007..To investigate the expression of Cyclooxygenase-2 (COX-2), proliferating cell nuclear antigen (PCNA), Ki-67 and p53 in gastrointestinal stromal tumors (GISTs) and its relationship with histopathological parameters...
