Research Topics
| E DincSummaryAffiliation: Ankara University Country: Turkey Publications
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Detail Information
Publications
Fractional-continuous wavelet transforms and ultra-performance liquid chromatography for the multicomponent analysis of a ternary mixture containing thiamine, pyridoxine, and lidocaine in ampulesErdal Dinc
Ankara University, Department of Analytical Chemistry, Faculty of Pharmacy, Ankara, Turkey
J AOAC Int 95:903-12. 2012..The proposed chemometric approaches (signal processing-multivariate calibrations) and UPLC method were applied to the quantitative multicomponent analysis of marketed ampules containing the vitamins B1 and B6 with LID...- A new application of continuous wavelet transform to overlapping chromatograms for the quantitative analysis of amiloride hydrochloride and hydrochlorothiazide in tablets by ultra-performance liquid chromatographyErdal Dinc
Ankara University, Department of Analytical Chemistry, Faculty of Pharmacy, Turkey
J AOAC Int 95:751-6. 2012..The experimental results indicated that the suggested UPLC-CWT signal processing provides accurate and precise results for industrial QC and quantitative evaluation of AML-HCT tablets... - Application of the wavelet method for the simultaneous quantitative determination of benazepril and hydrochlorothiazide in their mixturesErdal Dinc
Ankara University, Department of Analytical Chemistry, Faculty of Pharmacy, 06100, Tandogan, Ankara, Turkey
J AOAC Int 87:834-41. 2004..All calculations were performed within EXCEL, C++, and MATLAB6.5 softwares. The obtained results indicated that our approach was flexible and applicable for the binary mixture analysis... - Continuous wavelet transformation applied to the simultaneous quantitative analysis of two-component mixturesE Dinc
Department of Analytical Chemistry, Faculty of Pharmacy, University of Ankara, Tandogan, Turkey
Pharmazie 59:618-23. 2004..The method developed in this paper is rapid, easy to apply, inexpensive and is suitable for analysing the overlapping signals of compounds in their mixtures without any chemical pre-treatment... - Multivariate spectral calibration technique based on regression analysis for the quantitative multiresolution of a ternary mixture containing paracetamol, ascorbic acid and acetylsalicylic acid in effervescent tabletsE Dinc
Department of Analytical Chemistry, Faculty of Pharmacy, University of Ankara, Tandogan, Ankara, Turkey
Pharmazie 59:700-5. 2004..It was observed that TLRC and MLRC models give a successful quantitative multiresolution. The experimental results of these techniques were compared with each other as well as with those obtained by literature methods... - Comparative study of the continuous wavelet transform, derivative and partial least squares methods applied to the overlapping spectra for the simultaneous quantitative resolution of ascorbic acid and acetylsalicylic acid in effervescent tabletsErdal Dinc
Department of Analytical Chemistry, Faculty of Pharmacy, Ankara University, 06100 Tandogan, Ankara, Turkey
J Pharm Biomed Anal 37:569-75. 2005..A comparative study was carried out by using the experimental results obtained from three analytical methodologies and precise and accurate results were obtained... - Linear regression analysis and its application to multivariate chromatographic calibration for the quantitative analysis of two-component mixturesErdal Dinc
Department of Analytical Chemistry, Faculty of Pharmacy, University of Ankara, 06100 Tandogan, Ankara, Turkey
Farmaco 60:591-7. 2005..The obtained results were compared with those obtained by classical HPLC method. It was observed that the proposed multivariate chromatographic calibration gives better results than classical HPLC... - A new fractional wavelet approach for the simultaneous determination of ampicillin sodium and sulbactam sodium in a binary mixtureErdal Dinc
Department of Analytical Chemistry, Faculty of Pharmacy, Ankara University, 06100 Tandogan, Ankara, Turkey
Spectrochim Acta A Mol Biomol Spectrosc 63:631-8. 2006..Our proposed FWT approach was compared with the usual derivative spectrophotometry and chemometric methods (CLS, PCR and PLS) and a good agreement was reported... - Mathematical algorithms applied to the multi-linear regression functions for the multicomponent determination of pharmaceutical dosage form containing three-component mixturesErdal Dinc
Department of Analytical Chemistry, Faculty of Pharmacy, University of Ankara, 06100 Tandogan, Ankara, Turkey
Chem Pharm Bull (Tokyo) 53:899-906. 2005..In the comparison of TLRC and MLRC models to the classical approach, CRS technique, the successful assay results were observed for the quantitative multiresolution of ternary mixture of the subject active compounds... - Comparative application of wavelet approaches to absorption and ratio spectra for the simultaneous determination of diminazene aceturate and phenazone in veterinary granules for injectionE Dinc
Ankara University, Faculty of Pharmacy, Department of Analytical Chemistry, TR 06100 Tandogan, Ankara, Turkey
Pharmazie 60:892-6. 2005..The simultaneous quantitative analysis of DIMA and PHE in the commercial veterinary preparation was achieved by the elaborated methods. The assay results were compared with each other and good agreement was observed... - New liquid chromatographic-chemometric approach for the determination of sunset yellow and tartrazine in commercial preparationErdal Dinc
Ankara University, Faculty of Pharmacy, Department of Analytical Chemistry 06100, Tandogan, Ankara, Turkey
J AOAC Int 88:1748-55. 2005..The experimental results of the LC-chemometric approaches were compared with those obtained by a developed classical LC method using single-wavelength detection... - Fractional wavelet analysis for the simultaneous quantitative analysis of lacidipine and its photodegradation product by continuous wavelet transform and multilinear regression calibrationErdal Dinc
Ankara University, Faculty of Pharmacy, Department of Analytical Chemistry, 06100, Tandogan, Ankara, Turkey
J AOAC Int 89:1538-46. 2006..0-412.4 nm. Both methods were applied to the quantitative evaluation of LAC and LACD in laboratory and pharmaceutical samples, and produced very satisfactory results... - Comparative spectral analysis of veterinary powder product by continuous wavelet and derivative transformsErdal Dinc
Department of Analytical Chemistry, Faculty of Pharmacy, Ankara University, 06100 Tandogan, Ankara, Turkey
Spectrochim Acta A Mol Biomol Spectrosc 68:225-30. 2007..The experimental results obtained from the COIF-CWT approach were statistically compared with those obtained by classical derivative spectrophotometry and successful results were reported... - Simultaneous determination of trimethoprim and sulphamethoxazole in veterinary formulations by chromatographic multivariate methodsE Dinc
Department of Analytical Chemistry, Faculty of Pharmacy, Ankara University, 06100 Tandogan Ankara, Turkey
Pharmazie 62:179-84. 2007.... - Continuous wavelet and derivative transforms for the simultaneous quantitative analysis and dissolution test of levodopa-benserazide tabletsErdal Dinc
Department of Analytical Chemistry, Faculty of Pharmacy, Ankara University, 06100 Tandogan, Ankara, Turkey
J Pharm Biomed Anal 44:991-5. 2007..Each developed approaches were successfully applied to the simultaneous determination and dissolution test of levodopa and benserazide in their commercial tablets and a good agreement was observed... 
Simultaneous chemometric determination of pyridoxine hydrochloride and isoniazid in tablets by multivariate regression methodsErdal Dinc
Department of Analytical Chemistry, Faculty of Pharmacy, Ankara University, 06100 Tandogan, Ankara, Turkey
Drug Test Anal 2:383-7. 2010..The results obtained in this manuscript strongly encourage us to use them for the quality control and the routine analysis of the marketing tablets containing PYR and ISO drugs...- Multicomponent quantitative resolution of binary mixtures by using continuous wavelet transformErdal Dinc
University of Ankara, Faculty of Pharmacy, Department of Analytical Chemistry, 06100, Tandogan, Ankara, Turkey
J AOAC Int 87:360-5. 2004..MATLAB 6.5 software was used to perform the calculations. The results of our study were compared with those obtained by spectroscopic, chemometric, and liquid chromatographic methods, and good agreement was found... - A comparative study of the ratio spectra derivative spectrophotometry, Vierordt's method and high-performance liquid chromatography applied to the simultaneous analysis of caffeine and paracetamol in tabletsE Dinc
Department of Analytical Chemistry, Faculty of Pharmacy, University of Ankara, Turkey
J Pharm Biomed Anal 21:723-30. 1999..The results obtained by these spectrophotometric methods were compared with the results of HPLC method... - A comparison of matrix resolution method, ratio spectra derivative spectrophotometry and HPLC method for the determination of thiamine HCl and pyridoxine HCl in pharmaceutical preparationE Din
Department of Analytical Chemistry, Faculty of Pharmay, University of Ankara, Tandogan Ankara, Turkey
J Pharm Biomed Anal 22:915-23. 2000..In the HPLC method, the separation of these compounds was realized on a Nucleosil 100-5 C18 column with 0.1 M (NH4)2C03-water methanol (5:15:80 v/v) as the mobile phase. Results of spectrophotometric and HPLC procedures were compared... - Derivative ratio spectra-zero crossing spectrophotometry and LC method applied to the quantitative determination of paracetamol, propyphenazone and caffeine in ternary mixturesE Dinc
Department of Analytical Chemistry, Faculty of Pharmacy, University of Ankara, 06100, Tandogan Ankara, Turkey
J Pharm Biomed Anal 26:769-78. 2001..0-ml/min with an ultraviolet (UV) detection at 254 nm. Both methods were also applied to the determination of these three compounds in ternary mixtures and tablet formulation. The analytical results were quite good in all cases... - Spectrophotometric multicomponent analysis of a mixture of metamizol, acetaminophen and caffeine in pharmaceutical formulations by two chemometric techniquesE Dinc
Department of Analytical Chemistry, Faculty of Pharmacy, University of Ankara, 06100 Tandogan, Ankara, Turkey
J Pharm Biomed Anal 26:949-57. 2001..The techniques were successfully applied to two pharmaceutical formulations marketed in Turkey and results were compared with a new high-performance liquid chromatography method... - Two new spectrophotometric approaches to the multicomponent analysis of the acetaminophen and caffeine in tablets by classical least-squares and principal component regression techniquesE Dinc
Department of Analytical Chemistry, Faculty of Pharmacy, University of Ankara, Tandogan Ankara, Turkey
Farmaco 57:33-7. 2002..Our results were compared with those obtained previously by one of us considering HPLC method as a reference method. These two methods were successfully applied to a pharmaceutical tablet formulation of two drugs... - Simultaneous spectrophotometric determination of chlorphenoxamine hydrochloride and caffeine in a pharmaceutical preparation using first derivative of the ratio spectra and chemometric methodsErdal Dinc
Department of Analytical Chemistry, Faculty of Pharmacy, University of Ankara, 06100 Tandogan, Ankara, Turkey
J Pharm Biomed Anal 28:591-600. 2002..These three methods were successfully applied to a pharmaceutical formulation, sugar-coated tablet, and the results were compared with each other... - Spectrophotometric multicomponent resolution of a veterinary formulation containing oxfendazole and oxyclozanide by multivariate calibration-prediction techniquesErdal Dinc
Faculty of Pharmacy, Department of Analytical Chemistry, University of Ankara, 06100 Tandogan, Ankara, Turkey
J Pharm Biomed Anal 28:779-88. 2002..The results obtained were statistically compared with each other... - Simultaneous spectrophotometric determination of mefenamic acid and paracetamol in a pharmaceutical preparation using ratio spectra derivative spectrophotometry and chemometric methodsErdal Dinc
Department of Analytical Chemistry, Faculty of Pharmacy, University of Ankara, 06100 Tandogan, Ankara, Turkey
J Pharm Biomed Anal 28:1091-100. 2002..Mean recoveries were found satisfactory (>99%). The procedures do not require any separation step. These methods were successfully applied to a pharmaceutical formulation, tablet, and the results were compared with each other... - Chemometric resolution of a mixture containing hydrochlorothiazide and amiloride by absorption and derivative spectrophotometryErdal Dinc
Department of Analytical Chemistry, Faculty of Pharmacy, University of Ankara, 06100 Tandogan, Ankara, Turkey
J Pharm Biomed Anal 29:371-9. 2002..The results obtained by the proposed techniques based on the use of the measurements at the absorption spectra and at the first derivative spectra were statistically compared with each other... - Spectrophotometric quantitative determination of cilazapril and hydrochlorothiazide in tablets by chemometric methodsErdal Dinc
Department of Analytical Chemistry, Faculty of Pharmacy, University of Ankara, 06100, Tandogan, Ankara, Turkey
J Pharm Biomed Anal 30:715-23. 2002..The results of the methods were compared each other as well as with HPLC method and a good agreement was found... - Wavelet analysis for the multicomponent determination in a binary mixture of caffeine and propyphenazone in tabletsErdal Dinc
Department of Analytical Chemistry, Faculty of Pharmacy, Ankara University, Tandogan, Ankara 06100, Turkey
Farmaco 59:335-42. 2004..All calculations have been performed within EXCEL and Matlab 6.5 software. The obtained results indicate that our procedure is flexible and applicable for the mixture analysis... - Linear regression analysis and its application to the multivariate spectral calibrations for the multiresolution of a ternary mixture of caffeine, paracetamol and metamizol in tabletsErdal Dinc
Department of Analytical Chemistry, Faculty of Pharmacy, University of Ankara, Tandogan, Ankara 06100, Turkey
J Pharm Biomed Anal 33:605-15. 2003..The data treatments were carried out by the MAPLE V, EXCEL and SPSS 10.0 Softwares. The obtained results were successfully compared with each other as well as with those obtained by other literature methods... - Spectophotometric quantitative resolution of hydrochlorothiazide and spironolactone in tablets by chemometric analysis methodsErdal Dinc
Department of Analytical Chemistry, Faculty of Pharmacy, Ankara University, 06100 Tandogan, Ankara, Turkey
Farmaco 58:1151-61. 2003..The chemometrics analysis methods were satisfactorily applied to the simultaneous determination of hydrochlorothiazide and spironolactone in the pharmaceutical tablet formulation... - Simultaneous spectrophotometric determination of cyproterone acetate and estradiol valerate in pharmaceutical preparations by ratio spectra derivative and chemometric methodsErdal Dinc
Department of Analytical Chemistry, Faculty of Pharmacy, Ankara University, 06100 Tandogan, Ankara, Turkey
J Pharm Biomed Anal 32:539-47. 2003..The proposed methods were successfully applied to a pharmaceutical formulation, sugar-coated tablet, and the results were compared with each other... - A zero-crossing technique for the multidetermination of thiamine HCl and pyridoxine HCl in their mixture by using one-dimensional wavelet transformErdal Dinc
Department of Analytical Chemistry, Faculty of Pharmacy, University of Ankara, 06100 Tandogan, Ankara, Turkey
J Pharm Biomed Anal 31:969-78. 2003..The developed method is rapid, easy to apply, not expensive and suitable for analysing of the overlapping signals of compounds in their mixtures without any chemical pre-treatment... - Dissolution and assaying of multicomponent tablets by chemometric methods using computer-aided spectrophotometerE Dinc
Department of Analytical Chemistry, Faculty of Pharmacy, University of Ankara, 06100 Tandogan, Ankara, Turkey
Int J Pharm 250:339-50. 2003..More than 95% of drugs were dissolved within 15 min. All of the three-chemometric methods in this study can be satisfactorily used for the quantitative analysis and for dissolutions test of multicomponent dosage form... - Multivariate analysis of paracetamol, propiphenazone, caffeine and thiamine in quaternary mixtures by PCR, PLS and ANN calibrations applied on wavelet transform dataErdal Dinc
Department of Analytical Chemistry, Faculty of Pharmacy, Ankara University, 06100 Tandogan, Ankara, Turkey
J Pharm Biomed Anal 48:1471-5. 2008..The models were finally used to assay the studied drugs in the commercial pharmaceutical formulations... - Simultaneous resolution of a binary mixture of captopril and hydrochlorothiazide in tablets by bivariate and multivariate spectral calibrationsO Ustündağ
Department of Analytical Chemistry, Faculty of Pharmacy, University of Ankara, Tandogan, Ankara, Turkey
Pharmazie 58:623-8. 2003..Data treatment was performed using MAPLE V, EXCEL and SPSS 10.0 Software... - Chemometric determination of naproxen sodium and pseudoephedrine hydrochloride in tablets by HPLCErdal Dinc
Department of Analytical Chemistry, Faculty of Pharmacy, Ankara University, Turkey
Chem Pharm Bull (Tokyo) 54:415-21. 2006..The HPLC-chemometric approaches were applied to real samples containing drugs of interest. The experimental results obtained from HPLC-chemometric calibrations were compared with those obtained by a classic HPLC method... - Simultaneous spectrophotometric determination of pseudoephedrine hydrochloride and ibuprofen in a pharmaceutical preparation using ratio spectra derivative spectrophotometry and multivariate calibration techniquesI Murat Palabiyik
Department of Analytical Chemistry, Faculty of Pharmacy, University of Ankara, , Ankara, Turkey
J Pharm Biomed Anal 34:473-83. 2004..The accuracy and the precision of the methods have been determined and they have been validated by analyzing synthetic mixtures. The five methods were successfully applied to tablets and the results were compared with each other...