Gokalp Iscan

Summary

Affiliation: Anadolu University
Country: Turkey

Publications

  1. ncbi request reprint Antimicrobial and antioxidant activities of Stachys lavandulifolia subsp. lavandulifolia essential oil and its infusion
    Gokalp Iscan
    Department of Pharmacognosy, Faculty of Pharmacy, Anadolu University, 26470 Eskisehir, Turkey
    Nat Prod Commun 7:1241-4. 2012
  2. doi request reprint Biotransformation of (-)-(R)-α-phellandrene: antimicrobial activity of its major metabolite
    Gokalp Iscan
    Department of Pharmacognosy, Anadolu University, Faculty of Pharmacy, TR 26470, Eskisehir, Turkey
    Chem Biodivers 9:1525-32. 2012
  3. ncbi request reprint Biological activity and composition of the essential oils of Achillea schischkinii Sosn. and Achillea aleppica DC. subsp. aleppica
    Gokalp Iscan
    Department of Pharmacognosy, Faculty of Pharmacy, Anadolu University, 26470, Eskisehir, Turkey
    J Agric Food Chem 54:170-3. 2006
  4. doi request reprint Anticandidal activity of the essential oil of Nepeta transcaucasica Grossh
    Gokalp Iscan
    Department of Pharmacognosy, Anadolu University, Faculty of Pharmacy, Eskisehir
    Chem Biodivers 8:2144-8. 2011
  5. doi request reprint Synthesis and biological evaluation of some hydrazone derivatives as new anticandidal and anticancer agents
    Mehlika Dilek Altintop
    Anadolu University, Faculty of Pharmacy, Department of Pharmaceutical Chemistry, 26470 Eskisehir, Turkey
    Eur J Med Chem 58:299-307. 2012
  6. doi request reprint Preparation of some pyrazoline derivatives and evaluation of their antifungal activities
    Ahmet Ozdemir
    Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Anadolu University, Eskisehir, Turkey
    J Enzyme Inhib Med Chem 25:565-71. 2010
  7. ncbi request reprint Antimicrobial screening of Mentha piperita essential oils
    Gokalp Iscan
    Medicinal and Aromatic Plant and Drug Research Centre TBAM, Anadolu University, 26470 Eskisehir, Turkey
    J Agric Food Chem 50:3943-6. 2002
  8. ncbi request reprint The essential oil constituents and antimicrobial activity of Anthemis aciphylla BOISS. var. discoidea BOISS
    K Husnu Can Baser
    Department of Pharmacognosy, Faculty of Pharmacy, Anadolu University, Eskisehir, Turkey
    Chem Pharm Bull (Tokyo) 54:222-5. 2006
  9. doi request reprint Synthesis and the selective antifungal activity of 5,6,7,8-tetrahydroimidazo[1,2-a]pyridine derivatives
    Ahmet Ozdemir
    Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Anadolu University, 26470 Eskisehir, Turkey
    Eur J Med Chem 45:2080-4. 2010
  10. ncbi request reprint The bioactive essential oil of Heracleum sphondylium L. subsp. ternatum (Velen.) Brummitt
    Gokalp Iscan
    Medicinal and Aromatic Plant and Drug Research Centre TBAM, Anadolu University, 26470 Eskisehir, Turkey
    Z Naturforsch C 58:195-200. 2003

Detail Information

Publications12

  1. ncbi request reprint Antimicrobial and antioxidant activities of Stachys lavandulifolia subsp. lavandulifolia essential oil and its infusion
    Gokalp Iscan
    Department of Pharmacognosy, Faculty of Pharmacy, Anadolu University, 26470 Eskisehir, Turkey
    Nat Prod Commun 7:1241-4. 2012
    ..375 mg/mL. The prepared infusion of the flowering aerial parts showed weak antimicrobial effects against all the tested microorganisms, but demonstrated a remarkably radical scavenging activity (IC50: 3.9 microg/mL)...
  2. doi request reprint Biotransformation of (-)-(R)-α-phellandrene: antimicrobial activity of its major metabolite
    Gokalp Iscan
    Department of Pharmacognosy, Anadolu University, Faculty of Pharmacy, TR 26470, Eskisehir, Turkey
    Chem Biodivers 9:1525-32. 2012
    ..125 to >4 mg/ml) against various bacteria and especially against Candida species in comparison with its substrate (-)-(R)-α-phellandrene and standard antimicrobial agents...
  3. ncbi request reprint Biological activity and composition of the essential oils of Achillea schischkinii Sosn. and Achillea aleppica DC. subsp. aleppica
    Gokalp Iscan
    Department of Pharmacognosy, Faculty of Pharmacy, Anadolu University, 26470, Eskisehir, Turkey
    J Agric Food Chem 54:170-3. 2006
    ..When tested for their antimicrobial, antiinflammatory, and antinociceptive activities, the oil of A. aleppica subsp. aleppica showed significant antiinflammatory, antinociceptive, and moderate antimicrobial activities...
  4. doi request reprint Anticandidal activity of the essential oil of Nepeta transcaucasica Grossh
    Gokalp Iscan
    Department of Pharmacognosy, Anadolu University, Faculty of Pharmacy, Eskisehir
    Chem Biodivers 8:2144-8. 2011
    ..The oil showed good inhibitory effects against C. glabrata and C. tropicalis at minimal inhibitory concentrations (MICs) of 0.09 and 0.375 mg/ml, respectively...
  5. doi request reprint Synthesis and biological evaluation of some hydrazone derivatives as new anticandidal and anticancer agents
    Mehlika Dilek Altintop
    Anadolu University, Faculty of Pharmacy, Department of Pharmaceutical Chemistry, 26470 Eskisehir, Turkey
    Eur J Med Chem 58:299-307. 2012
    ..albicans (ATCC-90028) with a MIC value of 0.05 mg/mL. Compound 5 can be identified as the most promising anticancer agent against A549 cancer cell lines due to its inhibitory effect on A549 cell lines and low toxicity to NIH3T3 cells...
  6. doi request reprint Preparation of some pyrazoline derivatives and evaluation of their antifungal activities
    Ahmet Ozdemir
    Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Anadolu University, Eskisehir, Turkey
    J Enzyme Inhib Med Chem 25:565-71. 2010
    ..Their antifungal activities against Candida albicans, Candida glabrata, Candida utilis, Candida tropicalis, Candida krusei, and Candida parapsilosis were investigated. A significant level of activity was observed...
  7. ncbi request reprint Antimicrobial screening of Mentha piperita essential oils
    Gokalp Iscan
    Medicinal and Aromatic Plant and Drug Research Centre TBAM, Anadolu University, 26470 Eskisehir, Turkey
    J Agric Food Chem 50:3943-6. 2002
    ..Chemical compositions of the oils were analyzed by GC and GC/MS. Using the bioautography assay, menthol was found to be responsible for the antimicrobial activity of these oils...
  8. ncbi request reprint The essential oil constituents and antimicrobial activity of Anthemis aciphylla BOISS. var. discoidea BOISS
    K Husnu Can Baser
    Department of Pharmacognosy, Faculty of Pharmacy, Anadolu University, Eskisehir, Turkey
    Chem Pharm Bull (Tokyo) 54:222-5. 2006
    ..Furthermore, the biological activity of the essential oils was evaluated in various human pathogenic microorganisms using the broth microdilution method. Weak to moderate inhibitions (0.06-1.0 mg/ml) was observed...
  9. doi request reprint Synthesis and the selective antifungal activity of 5,6,7,8-tetrahydroimidazo[1,2-a]pyridine derivatives
    Ahmet Ozdemir
    Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Anadolu University, 26470 Eskisehir, Turkey
    Eur J Med Chem 45:2080-4. 2010
    ..016 mg/mL) against the screened Candida species. The same compound showed no in vitro toxicity up to 25 microg/mL concentration suggesting that its antifungal activity (MICs 0.016-1 mg/mL) is selective...
  10. ncbi request reprint The bioactive essential oil of Heracleum sphondylium L. subsp. ternatum (Velen.) Brummitt
    Gokalp Iscan
    Medicinal and Aromatic Plant and Drug Research Centre TBAM, Anadolu University, 26470 Eskisehir, Turkey
    Z Naturforsch C 58:195-200. 2003
    ..3%). Furthermore, antimicrobial activity of the oil was evaluated using microdilution broth and agar diffusion methods. The bioactive constituent of the essential oil was determined as 1-octanol by using a bioautography assay...
  11. doi request reprint Synthesis and anticandidal activity of new triazolothiadiazine derivatives
    Mehlika Dilek Altintop
    Anadolu University, Faculty of Pharmacy, Department of Pharmaceutical Chemistry, 26470 Eskisehir, Turkey
    Eur J Med Chem 46:5562-6. 2011
    ..The compounds were also investigated for their cytotoxic effects using MTT assay. Compound 2a exhibited the highest cytotoxic activity, whereas compound 2f possessed the lowest cytotoxic activity against NIH/3T3 cells...
  12. ncbi request reprint Studies on hydrazone derivatives as antifungal agents
    Ahmet Ozdemir
    Anadolu University, Faculty of Pharmacy, Department of Pharmaceutical Chemistry, Eskisehir, Turkey
    J Enzyme Inhib Med Chem 23:470-5. 2008
    ..A significant level of activity was observed...