- Claudin-18 gene structure, regulation, and expression is evolutionary conserved in mammalsOzlem Tureci
Ganymed Pharmaceuticals AG, Freiligrathstr Mainz, Germany
Gene 481:83-92. 2011..Given that CLDN18.2 is a novel drug target candidate, our data is also relevant for drug development as it reveals all six investigated mammalian species as suitable models for testing safety of CLDN18.2 targeting regimen...
- In silico strategy for detection of target candidates for antibody therapy of solid tumorsGerd Helftenbein
Ganymed Pharmaceuticals AG, Mainz, Germany
Gene 414:76-84. 2008..The impact of such stringent input control on accuracy of prediction is underlined by RT-PCR confirmation of predicted tissue distribution patterns for a number of selected candidates...