Musaffe Tuna

Summary

Publications

  1. doi request reprint Uniparental disomy in cancer
    Musaffe Tuna
    Department of Cancer Genetics, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA
    Trends Mol Med 15:120-8. 2009
  2. pmc Genomic sequencing in cancer
    Musaffe Tuna
    Department of Genetics, The University of Texas MD Anderson Cancer Center, Houston, TX, USA Electronic address
    Cancer Lett 340:161-70. 2013
  3. pmc Soft tissue sarcoma subtypes exhibit distinct patterns of acquired uniparental disomy
    Musaffe Tuna
    Department of Epidemiology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030 4009, USA
    BMC Med Genomics 5:60. 2012
  4. doi request reprint Prognostic value of acquired uniparental disomy (aUPD) in primary breast cancer
    Musaffe Tuna
    Department of Epidemiology, The University of Texas M D Anderson Cancer Center, Unit 1340, 1515 Holcombe Blvd, Houston, TX 77030 4009, USA
    Breast Cancer Res Treat 132:189-96. 2012
  5. pmc Association between acquired uniparental disomy and homozygous mutations and HER2/ER/PR status in breast cancer
    Musaffe Tuna
    Department of Epidemiology, The University of Texas M D Anderson Cancer Center, Houston, Texas, United States of America
    PLoS ONE 5:e15094. 2010
  6. ncbi request reprint HER2/neu increases the expression of Wilms' Tumor 1 (WT1) protein to stimulate S-phase proliferation and inhibit apoptosis in breast cancer cells
    Musaffe Tuna
    Department of Experimental Therapeutics, Unit 422, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX, USA
    Oncogene 24:1648-52. 2005

Detail Information

Publications6

  1. doi request reprint Uniparental disomy in cancer
    Musaffe Tuna
    Department of Cancer Genetics, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA
    Trends Mol Med 15:120-8. 2009
    ..This review summarizes the mechanisms underlying UPD and their emerging association with cancer...
  2. pmc Genomic sequencing in cancer
    Musaffe Tuna
    Department of Genetics, The University of Texas MD Anderson Cancer Center, Houston, TX, USA Electronic address
    Cancer Lett 340:161-70. 2013
    ..Hence in this review, we focus on whole-genome sequencing in cancer. ..
  3. pmc Soft tissue sarcoma subtypes exhibit distinct patterns of acquired uniparental disomy
    Musaffe Tuna
    Department of Epidemiology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030 4009, USA
    BMC Med Genomics 5:60. 2012
    ..STS can be classified into two main categories according to the type of genomic alteration: recurrent translocation driven STS, and non-recurrent translocations. However, little has known about acquired uniparental disomy in STS...
  4. doi request reprint Prognostic value of acquired uniparental disomy (aUPD) in primary breast cancer
    Musaffe Tuna
    Department of Epidemiology, The University of Texas M D Anderson Cancer Center, Unit 1340, 1515 Holcombe Blvd, Houston, TX 77030 4009, USA
    Breast Cancer Res Treat 132:189-96. 2012
    ..We thus conclude that aUPD is a frequent event in breast cancer and that aUPD at specific regions in the genome has implications in this disease...
  5. pmc Association between acquired uniparental disomy and homozygous mutations and HER2/ER/PR status in breast cancer
    Musaffe Tuna
    Department of Epidemiology, The University of Texas M D Anderson Cancer Center, Houston, Texas, United States of America
    PLoS ONE 5:e15094. 2010
    ..A novel form of abnormality called acquired uniparental disomy (aUPD) was recently found to pinpoint the region of mutated genes in various cancers, thereby identifying the region for next-generation sequencing...
  6. ncbi request reprint HER2/neu increases the expression of Wilms' Tumor 1 (WT1) protein to stimulate S-phase proliferation and inhibit apoptosis in breast cancer cells
    Musaffe Tuna
    Department of Experimental Therapeutics, Unit 422, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX, USA
    Oncogene 24:1648-52. 2005
    ..Our data indicate that HER2/neu engages Akt to increase WT1 expression, and that WT1 protein plays a vital role in regulating cell cycle progression and apoptosis in HER2/neu-overexpressing breast cancer cells...