Komlódi T, Geibl F, Sassani M, Ambrus A, Tretter L. Membrane potential and delta pH dependency of reverse electron transport-associated hydrogen peroxide production in brain and heart mitochondria. J Bioenerg Biomembr. 2018;50:355-365 pubmed publisher
..Minor decrease of Δψm might be applied as a therapeutic strategy to attenuate RET-driven ROS generation in ischemia-reperfusion injury. ..
Tretter L, Ambrus A. Measurement of ROS homeostasis in isolated mitochondria. Methods Enzymol. 2014;547:199-223 pubmed publisher
..All other relevant technical considerations including advantages/disadvantages of the various methods and the most common artifacts are also discussed. ..
Mikulás K, Hermann P, Gera I, Komlódi T, Horváth G, Ambrus A, et al
. Triethylene glycol dimethacrylate impairs bioenergetic functions and induces oxidative stress in mitochondria via inhibiting respiratory Complex I. Dent Mater. 2018;34:e166-e181 pubmed publisher
..Identification of the molecular target of TEGDMA may influence the development of relevant biomaterials and may induce new therapeutic strategies to control the adverse effects of resin monomers. ..
KomlÃ³di T, Tretter L. Methylene blue stimulates substrate-level phosphorylation catalysed by succinyl-CoA ligase in the citric acid cycle. Neuropharmacology. 2017;123:287-298 pubmed publisher
..The mitochondrial effects of MB are explained by the ability to accept electrons from reducing equivalents and transfer them to cytochrome c bypassing the respiratory Complexes I and III. ..
Nagy A, Fekete R, Horváth G, Koncsos G, Kriston C, Sebestyen A, et al
. Versatility of microglial bioenergetic machinery under starving conditions. Biochim Biophys Acta Bioenerg. 2018;1859:201-214 pubmed publisher
..Our finding that microglia have a distinct bioenergetic profile provides a critical foundation for specifying microglial contributions to brain energy metabolism. ..