Suicide attempts in major affective disorder patients with comorbid substance use disordersL Tondo
International Consortium for Research on Bipolar Disorders the Department of Psychiatry, Harvard Medical School, Boston, Mass, USA
J Clin Psychiatry 60:63-9; discussion 75-6, 113-6. 1999
..The widely accepted impression that substance abuse and dependence are associated with increased suicidal risk was evaluated by literature review and with new data...
Effectiveness of maintenance electroconvulsive therapy in rapid-cycling bipolar disorderGian Paolo Minnai
Servizio Psichiatrico di Diagnosi e Cura, Ospedale San Martino, Oristano, Sardinia
J ECT 27:123-6. 2011
..To evaluate the effectiveness of maintenance electroconvulsive therapy (m-ECT) in rapid-cycling (RC) bipolar disorder (BPD) patients...
- Long-term clinical effectiveness of lithium maintenance treatment in types I and II bipolar disorders
L Tondo
Department of Psychology, University of Cagliari, Sardinia, Italy and McLean Hospital, Department of Psychiatry, Harvard Medical School, Boston, USA
Br J Psychiatry Suppl 41:s184-90. 2001
..The effectiveness of lithium is being questioned increasingly and requires clarification...
- Effects of rapid cycling on response to lithium maintenance treatment in 360 bipolar I and II disorder patients
R J Baldessarini
International Consortium for Bipolar Disorder Research, MA, Boston, USA
J Affect Disord 61:13-22. 2000
..Rapid cycling (RC) in bipolar disorders is widely believed to predict future morbidity and poor treatment response, although empirical testing of its predictive utility remains limited...
- Latency and episodes before treatment: response to lithium maintenance in bipolar I and II disorders
R J Baldessarini
Consolidated Department of Psychiatry, Harvard Medical School and Bipolar and Psychotic Disorders Program, McLean Massachusetts General Hospitals, Boston, USA
Bipolar Disord 1:91-7. 1999
..To test whether longer treatment-delays or more pretreatment illness episodes are followed by diminished response to lithium maintenance...
- Discontinuing lithium maintenance treatment in bipolar disorders: risks and implications
R J Baldessarini
The International Consortium for Bipolar Disorders Research, Consolidated Department of Psychiatry and Neuroscience Program, Harvard Medical School, Boston, MA, USA
Bipolar Disord 1:17-24. 1999
..To review research findings on clinical effects of discontinuing lithium maintenance treatment...
- Age at onset in 3014 Sardinian bipolar and major depressive disorder patients
L Tondo
Department of Psychiatry, Harvard Medical School and International Consortium for Psychotic and Mood Disorders Research, McLean Division of Massachusetts General Hospital, Boston, MA, USA
Acta Psychiatr Scand 121:446-52. 2010
..To test if onset age in major affective illnesses is younger in bipolar disorder (BPD) than unipolar-major depressive disorder (UP-MDD), and is a useful measure...
- Suicidal status during antidepressant treatment in 789 Sardinian patients with major affective disorder
L Tondo
Department of Psychiatry and Neuroscience Program, Harvard Medical School and McLean Division of Massachusetts General Hospital, Boston, MA, USA
Acta Psychiatr Scand 118:106-15. 2008
..Relationships between antidepressant treatment and suicidality remain uncertain in major depressive disorder (MDD), and rarely evaluated in bipolar disorder (BPD)...
- Response to lithium maintenance treatment in bipolar disorders: comparison of women and men
A C Viguera
The International Consortium for Bipolar Disorder Research, Boston, Massachusetts, USA
Bipolar Disord 3:245-52. 2001
..Since women with bipolar disorder reportedly have more features that may predict a poor prognosis (depression and rapid cycling), we tested the hypothesis that women respond less well to lithium maintenance treatment...
- Reproduction among 1975 Sardinian women and men diagnosed with major mood disorders
L Tondo
International Consortium for Psychotic and Mood Disorder Research, McLean Hospital and Harvard Medical School, Boston, MA, USA
Acta Psychiatr Scand 123:283-9. 2011
..It may include reproductive functioning, which has rarely been studied systematically...
- Sex differences in response to lithium treatment
A C Viguera
Department of Psychiatry, Massachusetts General Hospital, Boston, MA 02114, USA
Am J Psychiatry 157:1509-11. 2000
..The authors' goal was to investigate whether there are differences between the sexes in response to lithium...
- Treating the suicidal patient with bipolar disorder. Reducing suicide risk with lithium
R J Baldessarini
Department of Psychiatry and Neuroscience Program, Harvard Medical School, and Bipolar and Psychotic Disorders Program, Mailman Research Center, McLean Division of Massachusetts General Hospital, Belmont, Massachusetts 02478, USA
Ann N Y Acad Sci 932:24-38; discussion 39-43. 2001
..Studies of commonly used, but incompletely evaluated, alternative treatments are required, and further protection against premature mortality can be anticipated with better protection against bipolar depression...
- Pharmacologic interventions in suicide prevention
L Tondo
Department of Psychology, University of Cagliari, Sardinia, Italy
J Clin Psychiatry 62:51-5. 2001
..Lithium is the only medication for which the evidence consistently shows an antisuicidal effect...
- Suicidal risks among 2826 Sardinian major affective disorder patients
L Tondo
Department of Psychiatry and Neuroscience Program, Harvard Medical School and McLean Division of Massachusetts General Hospital, Boston, MA, USA
Acta Psychiatr Scand 116:419-28. 2007
..We estimated risks of suicidal behaviors in 2826 mood-disorder patients evaluated and followed in a Sardinian mood disorders research center over the past 30 years...
- Lower suicide risk with long-term lithium treatment in major affective illness: a meta-analysis
L Tondo
Consolidated Department of Psychiatry and Neuroscience Program, Harvard Medical School, Boston, Massachusetts, USA
Acta Psychiatr Scand 104:163-72. 2001
..CONCLUSION: Suicide risk was consistently lower during long-term treatment of major affective illnesses with lithium in all studies in the meta-analysis, including the few involving treatment-randomization...
- Onset-age of bipolar disorders at six international sites
R J Baldessarini
Department of Psychiatry and Neuroscience Program, Harvard Medical School, USA
J Affect Disord 121:143-6. 2010
....
- Mania associated with antidepressant treatment: comprehensive meta-analytic review
L Tondo
Department of Psychiatry and Neuroscience Program, Harvard Medical School and McLean Division of Massachusetts General Hospital, Boston, MA, USA
Acta Psychiatr Scand 121:404-14. 2010
..To review available data pertaining to risk of mania-hypomania among bipolar (BPD) and major depressive disorder (MDD) patients with vs. without exposure to antidepressant drugs (ADs) and consider effects of mood stabilizers...
- Comorbid substance-use in schizophrenia: relation to positive and negative symptoms
A Talamo
Department of Psychiatry, Harvard Medical School, Boston, MA, USA
Schizophr Res 86:251-5. 2006
..Comorbid SUD in schizophrenia patients was associated with male sex and higher PANSS positive to lower negative scores. Cause-effect relationships remain to be clarified...
- Intensive treatment with lithium carbonate "once a day" in bipolar patients
L Tondo
Department of Psychology, University of Cagliari, Stanley Foundation Research Center Lucio Bini, Cagliari, Italy
Clin Ter 152:277-80. 2001
..quot;Once a day" lithium carbonate appears to be a useful alternative to the standard preparation, and may potentially improve treatment compliance by simplifying patients' medication...
- Rapid-cycling bipolar disorder: effects of long-term treatments
L Tondo
Department of Psychiatry and Neuroscience Program, Harvard Medical School, USA
Acta Psychiatr Scand 108:4-14. 2003
..Additional long-term studies comparing RC/non-RC patients randomized to specific treatments are required...
- The Italian version of the validated short TEMPS-A: the temperament evaluation of Memphis, Pisa, Paris and San Diego
A Preti
Department of Psychology, University of Cagliari, via Is Mirrionis 1, 09123 Cagliari, Italy
J Affect Disord 120:207-12. 2010
..This study presents the Italian brief, 39-item version of the questionnaire, more suited for studies in populations and currently validated in the U.S., and in a French translation...
