M Tolnay

Summary

Publications

  1. ncbi request reprint Protein kinase A regulatory subunit type II beta directly interacts with and suppresses CREB transcriptional activity in activated T cells
    Michael R Elliott
    Department of Microbiology and Immunology, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA
    J Immunol 171:3636-44. 2003
  2. pmc Heterogeneous nuclear ribonucleoprotein D0B is a sequence-specific DNA-binding protein
    M Tolnay
    Department of Clinical Physiology, Walter Reed Army Institute of Research, 14th and Dahlia Streets, Bldg 40, Washington, DC 20307 5100, USA
    Biochem J 338:417-25. 1999
  3. ncbi request reprint NF-kappaB regulates the expression of the human complement receptor 2 gene
    Mate Tolnay
    Department of Cellular Injury, Walter Reed Army Institute of Research, Silver Spring, MD 20910, USA
    J Immunol 169:6236-43. 2002
  4. pmc Protein kinase A enhances, whereas glycogen synthase kinase-3 beta inhibits, the activity of the exon 2-encoded transactivator domain of heterogeneous nuclear ribonucleoprotein D in a hierarchical fashion
    Mate Tolnay
    Walter Reed Army Institute of Research, Silver Spring, MD 20910, USA
    Biochem J 363:127-36. 2002
  5. ncbi request reprint Serum regulates the expression of complement receptor 2 on human B cell lines
    M Tolnay
    Department of Cellular Injury, Walter Reed Army Institute of Research, Washington, DC 20307 5100, USA
    Immunopharmacol Immunotoxicol 22:205-19. 2000
  6. pmc Heterogeneous nuclear ribonucleoprotein D0 contains transactivator and DNA-binding domains
    M Tolnay
    Department of Cellular Injury, Walter Reed Army Institute of Research, Silver Spring, MD 20910, USA
    Biochem J 348:151-8. 2000
  7. ncbi request reprint Multiple transcription factors regulate the inducible expression of the human complement receptor 2 promoter
    L A Vereshchagina
    Department of Cellular Injury, Walter Reed Army Institute of Research, Silver Spring, MD 20910, USA
    J Immunol 166:6156-63. 2001
  8. ncbi request reprint The cyclic adenosine 5'-monophosphate response element modulator suppresses IL-2 production in stimulated T cells by a chromatin-dependent mechanism
    Klaus Tenbrock
    Department of Cellular Injury, Walter Reed Army Institute of Research, Silver Spring, MD 20910, USA
    J Immunol 170:2971-6. 2003
  9. ncbi request reprint Elf-1 binds to GGAA elements on the FcRgamma promoter and represses its expression
    Yuang Taung Juang
    Department of Cellular Injury, Walter Reed Army Institute of Research, Silver Spring, MD 20910, USA
    J Immunol 179:4884-9. 2007
  10. ncbi request reprint The cyclic AMP response element modulator regulates transcription of the TCR zeta-chain
    Klaus Tenbrock
    Department of Pediatrics, Division of Rheumatology, University Hospital, Muenster, Germany
    J Immunol 175:5975-80. 2005

Collaborators

Detail Information

Publications11

  1. ncbi request reprint Protein kinase A regulatory subunit type II beta directly interacts with and suppresses CREB transcriptional activity in activated T cells
    Michael R Elliott
    Department of Microbiology and Immunology, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA
    J Immunol 171:3636-44. 2003
    ..We conclude that nuclear RIIbeta can act as a repressor of CREB transcriptional activity in T cells, providing a potential functional significance for aberrant levels of nuclear RIIbeta in systemic lupus erythematosus T cells...
  2. pmc Heterogeneous nuclear ribonucleoprotein D0B is a sequence-specific DNA-binding protein
    M Tolnay
    Department of Clinical Physiology, Walter Reed Army Institute of Research, 14th and Dahlia Streets, Bldg 40, Washington, DC 20307 5100, USA
    Biochem J 338:417-25. 1999
    ..Our results suggest a new physiological role for hnRNP D0B that involves binding to double- and single-stranded DNA sequences in a specific manner and functioning as a transcription factor...
  3. ncbi request reprint NF-kappaB regulates the expression of the human complement receptor 2 gene
    Mate Tolnay
    Department of Cellular Injury, Walter Reed Army Institute of Research, Silver Spring, MD 20910, USA
    J Immunol 169:6236-43. 2002
    ..Thus, at the onset of an infection, LPS could sensitize the B cell to Ag by enhancing the level of CR2-costimulatory molecules on the cell surface...
  4. pmc Protein kinase A enhances, whereas glycogen synthase kinase-3 beta inhibits, the activity of the exon 2-encoded transactivator domain of heterogeneous nuclear ribonucleoprotein D in a hierarchical fashion
    Mate Tolnay
    Walter Reed Army Institute of Research, Silver Spring, MD 20910, USA
    Biochem J 363:127-36. 2002
    ....
  5. ncbi request reprint Serum regulates the expression of complement receptor 2 on human B cell lines
    M Tolnay
    Department of Cellular Injury, Walter Reed Army Institute of Research, Washington, DC 20307 5100, USA
    Immunopharmacol Immunotoxicol 22:205-19. 2000
    ..Because stimuli that alter CR2 expression can influence the extent of the B cell response to antigen-C3d complexes, serum factors may play a role in regulating the responsiveness of B cells...
  6. pmc Heterogeneous nuclear ribonucleoprotein D0 contains transactivator and DNA-binding domains
    M Tolnay
    Department of Cellular Injury, Walter Reed Army Institute of Research, Silver Spring, MD 20910, USA
    Biochem J 348:151-8. 2000
    ..We propose that the B isoform of hnRNP D0 functions in the nucleus as a DNA-binding transactivator and has distinct transactivator and DNA-binding domains...
  7. ncbi request reprint Multiple transcription factors regulate the inducible expression of the human complement receptor 2 promoter
    L A Vereshchagina
    Department of Cellular Injury, Walter Reed Army Institute of Research, Silver Spring, MD 20910, USA
    J Immunol 166:6156-63. 2001
    ..Our studies may provide insights to novel approaches to modulate B cell function by regulating CR2 gene transcription...
  8. ncbi request reprint The cyclic adenosine 5'-monophosphate response element modulator suppresses IL-2 production in stimulated T cells by a chromatin-dependent mechanism
    Klaus Tenbrock
    Department of Cellular Injury, Walter Reed Army Institute of Research, Silver Spring, MD 20910, USA
    J Immunol 170:2971-6. 2003
    ..CREM, in turn, binds protein 300 and cAMP response element binding protein, but CREM is unable to activate its histone acetyltransferase activity, which results in condensation of chromatin and down-regulation of IL-2 production...
  9. ncbi request reprint Elf-1 binds to GGAA elements on the FcRgamma promoter and represses its expression
    Yuang Taung Juang
    Department of Cellular Injury, Walter Reed Army Institute of Research, Silver Spring, MD 20910, USA
    J Immunol 179:4884-9. 2007
    ....
  10. ncbi request reprint The cyclic AMP response element modulator regulates transcription of the TCR zeta-chain
    Klaus Tenbrock
    Department of Pediatrics, Division of Rheumatology, University Hospital, Muenster, Germany
    J Immunol 175:5975-80. 2005
    ..Our studies demonstrate that CREM alpha binds to the TCR zeta promoter and repress its activity...
  11. ncbi request reprint Epstein-Barr virus nuclear antigen 2 induces FcRH5 expression through CBF1
    Joanne Mohan
    Division of Monoclonal Antibodies, Center for Drug Evaluation and Research, Food and Drug Administration, Rockville, MD 20857, USA
    Blood 107:4433-9. 2006
    ..These results identify FcRH5 as a novel, direct target of EBNA2 that may contribute to the development of Epstein-Barr virus-associated tumors...