Gergely Toldi

Summary

Publications

  1. doi request reprint Relevance of novel inflammatory markers in stroke-induced immunosuppression
    András Folyovich
    First Department of Pediatrics, Semmelweis University, Budapest, Bókay u, 53 54 H 1083, Hungary
    BMC Neurol 14:41. 2014
  2. ncbi request reprint Soluble urokinase plasminogen activator receptor (suPAR) in the assessment of inflammatory activity of rheumatoid arthritis patients in remission
    Gergely Toldi
    First Department of Pediatrics, Semmelweis University, Budapest, Bókay u 53 54, 1083 Hungary
    Clin Chem Lab Med 51:327-32. 2013
  3. doi request reprint B7 costimulation and intracellular indoleamine-2,3-dioxygenase expression in peripheral blood of healthy pregnant and pre-eclamptic women
    Gergely Toldi
    First Department of Pediatrics, Semmelweis University, Budapest, Hungary
    Am J Reprod Immunol 69:264-71. 2013
  4. doi request reprint Plasma soluble urokinase plasminogen activator receptor (suPAR) levels in ankylosing spondylitis
    Gergely Toldi
    First Department of Pediatrics, Semmelweis University, Bókay u 53 54, 1083 Budapest, Hungary
    Joint Bone Spine 80:96-8. 2013
  5. doi request reprint The effects of Kv1.3 and IKCa1 potassium channel inhibition on calcium influx of human peripheral T lymphocytes in rheumatoid arthritis
    Gergely Toldi
    First Department of Pediatrics, Semmelweis University, Budapest, Hungary
    Immunobiology 218:311-6. 2013
  6. doi request reprint Soluble urokinase plasminogen activator receptor (suPAR) levels in healthy pregnancy and preeclampsia
    Gergely Toldi
    First Department of Pediatrics, Semmelweis University, Budapest, Hungary
    Clin Chem Lab Med 49:1873-6. 2011
  7. doi request reprint Human Th1 and Th2 lymphocytes are distinguished by calcium flux regulation during the first 10 min of lymphocyte activation
    Gergely Toldi
    First Department of Pediatrics, Semmelweis University, Bókay u 53 54, Budapest H 1083, Hungary
    Immunobiology 217:37-43. 2012
  8. doi request reprint Lymphocyte calcium influx characteristics and their modulation by Kv1.3 and IKCa1 channel inhibitors in healthy pregnancy and preeclampsia
    Gergely Toldi
    First Department of Pediatrics, Semmelweis University, Budapest, Hungary
    Am J Reprod Immunol 65:154-63. 2011
  9. doi request reprint T-lymphocyte calcium influx characteristics and their modulation by Kv1.3 and IKCa1 channel inhibitors in the neonate
    Gergely Toldi
    First Department of Pediatrics, Semmelweis University, Bókay u 53 54, Budapest H 1083, Hungary
    Int Immunol 22:769-74. 2010
  10. doi request reprint Lymphocyte activation in type 1 diabetes mellitus: the increased significance of Kv1.3 potassium channels
    Gergely Toldi
    First Department of Pediatrics, Semmelweis University, Budapest H 1083, Hungary
    Immunol Lett 133:35-41. 2010

Collaborators

Detail Information

Publications26

  1. doi request reprint Relevance of novel inflammatory markers in stroke-induced immunosuppression
    András Folyovich
    First Department of Pediatrics, Semmelweis University, Budapest, Bókay u, 53 54 H 1083, Hungary
    BMC Neurol 14:41. 2014
    ..We aimed to identify an inflammatory marker that best represents this biphasic immunological response after AIS...
  2. ncbi request reprint Soluble urokinase plasminogen activator receptor (suPAR) in the assessment of inflammatory activity of rheumatoid arthritis patients in remission
    Gergely Toldi
    First Department of Pediatrics, Semmelweis University, Budapest, Bókay u 53 54, 1083 Hungary
    Clin Chem Lab Med 51:327-32. 2013
    ..We aimed to evaluate suPAR for the assessment of inflammatory activity in rheumatoid arthritis (RA) patients in remission...
  3. doi request reprint B7 costimulation and intracellular indoleamine-2,3-dioxygenase expression in peripheral blood of healthy pregnant and pre-eclamptic women
    Gergely Toldi
    First Department of Pediatrics, Semmelweis University, Budapest, Hungary
    Am J Reprod Immunol 69:264-71. 2013
    ..We also examined the intracellular expression of indoleamine-2,3-dioxygenase (IDO)...
  4. doi request reprint Plasma soluble urokinase plasminogen activator receptor (suPAR) levels in ankylosing spondylitis
    Gergely Toldi
    First Department of Pediatrics, Semmelweis University, Bókay u 53 54, 1083 Budapest, Hungary
    Joint Bone Spine 80:96-8. 2013
    ..In line with earlier findings, our results indicate that, unlike suPAR, both of these markers are positively correlated with disease activity in AS...
  5. doi request reprint The effects of Kv1.3 and IKCa1 potassium channel inhibition on calcium influx of human peripheral T lymphocytes in rheumatoid arthritis
    Gergely Toldi
    First Department of Pediatrics, Semmelweis University, Budapest, Hungary
    Immunobiology 218:311-6. 2013
    ..Kv1.3 and IKCa1 potassium channels are important regulators of the maintenance of calcium influx during lymphocyte activation and present a possible target for selective immunomodulation...
  6. doi request reprint Soluble urokinase plasminogen activator receptor (suPAR) levels in healthy pregnancy and preeclampsia
    Gergely Toldi
    First Department of Pediatrics, Semmelweis University, Budapest, Hungary
    Clin Chem Lab Med 49:1873-6. 2011
    ..We aimed to assess the levels of suPAR and other markers of systemic inflammation in preeclampsia compared to healthy pregnancy...
  7. doi request reprint Human Th1 and Th2 lymphocytes are distinguished by calcium flux regulation during the first 10 min of lymphocyte activation
    Gergely Toldi
    First Department of Pediatrics, Semmelweis University, Bókay u 53 54, Budapest H 1083, Hungary
    Immunobiology 217:37-43. 2012
    ..The observed differences in calcium flux of Th1 and Th2 cells may contribute to different calcium handling kinetics and, hence, to distinct cytokine production patterns by these subsets...
  8. doi request reprint Lymphocyte calcium influx characteristics and their modulation by Kv1.3 and IKCa1 channel inhibitors in healthy pregnancy and preeclampsia
    Gergely Toldi
    First Department of Pediatrics, Semmelweis University, Budapest, Hungary
    Am J Reprod Immunol 65:154-63. 2011
    ..We compared the activation-elicited calcium influx in T lymphocytes in HP, PE and non-P women and tested its alteration upon inhibition of Kv1.3 and IKCa1 potassium channels...
  9. doi request reprint T-lymphocyte calcium influx characteristics and their modulation by Kv1.3 and IKCa1 channel inhibitors in the neonate
    Gergely Toldi
    First Department of Pediatrics, Semmelweis University, Bókay u 53 54, Budapest H 1083, Hungary
    Int Immunol 22:769-74. 2010
    ..The altered function of neonatal lymphocyte potassium channels may contribute to this phenomenon...
  10. doi request reprint Lymphocyte activation in type 1 diabetes mellitus: the increased significance of Kv1.3 potassium channels
    Gergely Toldi
    First Department of Pediatrics, Semmelweis University, Budapest H 1083, Hungary
    Immunol Lett 133:35-41. 2010
    ..Therefore, the proposed inhibition of Kv1.3 channels as a novel therapeutic approach for the treatment of type 1 diabetes mellitus may have a major effect on overall lymphocyte function in this disease...
  11. doi request reprint Lymphocyte calcium influx kinetics in multiple sclerosis treated without or with interferon β
    Gergely Toldi
    First Department of Pediatrics, Semmelweis University, Budapest, Bókay u 53 54, H 1083, Hungary
    J Neuroimmunol 237:80-6. 2011
    ..3 channels in multiple sclerosis patients without interferon-beta. However, this effect is not specific enough concerning all lymphocyte subsets influencing the autoimmune response, since it also affects anti-inflammatory Th2 cells...
  12. doi request reprint Hepcidin concentrations and iron homeostasis in preeclampsia
    Gergely Toldi
    First Department of Pediatrics, Semmelweis University, Budapest, Hungary
    Clin Chem Lab Med 48:1423-6. 2010
    ..This is in contrast to inflammation characteristic for PE. The link between iron homeostasis and inflammation is hepcidin. Our goal was to describe hepcidin concentrations and its association with iron homeostasis in PE...
  13. doi request reprint Analysis by flow cytometry of calcium influx kinetics in peripheral lymphocytes of patients with rheumatoid arthritis
    Anna Bajnok
    First Department of Pediatrics, Semmelweis University, Budapest, Bókay u 53 54, H 1083, Hungary
    Cytometry A 83:287-93. 2013
    ..The function fitting algorithm applied by FacsKin is suitable to provide a common basis for evaluating and comparing flow cytometry kinetic data...
  14. doi request reprint Prevalence of intracellular galectin-1-expressing lymphocytes in umbilical cord blood in comparison with adult peripheral blood
    Szonja Kollár
    First Department of Pediatrics, Semmelweis University, Budapest, Hungary
    Biol Blood Marrow Transplant 18:1608-13. 2012
    ..This suggests that Gal-1-expressing lymphocytes are unlikely to play a major role in mitigating the immune reactivity of UCB...
  15. doi request reprint Plasma soluble urokinase plasminogen activator receptor (suPAR) levels in systemic lupus erythematosus
    Gergely Toldi
    First Department of Pediatrics, Semmelweis University, Budapest, Hungary
    Biomarkers 17:758-63. 2012
    ..Soluble urokinase plasminogen activator receptor (suPAR) is a biomarker of systemic inflammation. We aimed to characterize plasma suPAR levels in SLE patients...
  16. pmc Relationship of circulating soluble urokinase plasminogen activator receptor (suPAR) levels to disease control in asthma and asthmatic pregnancy
    Istvan Ivancso
    Department of Pulmonology, Semmelweis University, Budapest, Hungary
    PLoS ONE 8:e60697. 2013
    ..Decrease in circulating suPAR levels detected both in healthy and asthmatic pregnant women presumably represents pregnancy induced immune tolerance...
  17. doi request reprint The frequency of peripheral blood CD4+ CD25high FoxP3+ and CD4+ CD25- FoxP3+ regulatory T cells in normal pregnancy and pre-eclampsia
    Gergely Toldi
    First Department of Pediatrics, Semmelweis University, Budapest, Hungary
    Am J Reprod Immunol 68:175-80. 2012
    ..We also examined the proportion of the activated CD4+ CD25high FoxP3high Treg subset within conventional Treg cells...
  18. doi request reprint Peripheral T(h)1/T(h)2/T(h)17/regulatory T-cell balance in asthmatic pregnancy
    Gergely Toldi
    1st Department of Pediatrics, Semmelweis University, H 1085 Budapest, Hungary
    Int Immunol 23:669-77. 2011
    ..44% versus 2.78%; P < 0.05). The abnormal asthma-dependent T(h)17 elevation together with blunted Treg increase may play a role in the compromised immune tolerance characterizing asthmatic pregnancy...
  19. doi request reprint Increased prevalence of peripheral blood granulysin-producing cytotoxic T lymphocytes in preeclampsia
    Attila Molvarec
    First Department of Obstetrics and Gynecology, Semmelweis University, Budapest, Hungary
    J Reprod Immunol 91:56-63. 2011
    ....
  20. pmc Kinetic measurements using flow cytometry: new methods for monitoring intracellular processes
    Gergo Mészáros
    First Department of Pediatrics, Semmelweis University, Budapest, Hungary
    Assay Drug Dev Technol 10:97-104. 2012
    ..The present methodology provides an opportunity for monitoring and characterizing mitochondrial Ca(2+) levels, plasma membrane potential, and superoxide generation in PHA-activated or rotenone-treated Jurkat cells with flow cytometry...
  21. doi request reprint Increased prevalence of IL-17-producing peripheral blood lymphocytes in pre-eclampsia
    Gergely Toldi
    First Department of Pediatrics, Semmelweis University, Budapest, Hungary
    Am J Reprod Immunol 66:223-9. 2011
    ..We aimed to describe the prevalence of these four CD4 lymphocyte subtypes in pre-eclampsia and normal pregnancy, along with that of IL-17-producing CD8 and NK cells...
  22. doi request reprint Peripheral blood galectin-1-expressing T and natural killer cells in normal pregnancy and preeclampsia
    Attila Molvarec
    First Department of Obstetrics and Gynecology, Semmelweis University, Budapest, Hungary
    Clin Immunol 139:48-56. 2011
    ..However, the proportion of galectin-1-expressing peripheral blood T and NK cells was markedly decreased in PE compared to normal pregnancy, which might contribute to the activation of innate and acquired immune cells...
  23. doi request reprint Decreased number of FoxP3+ regulatory T cells in preeclampsia
    Gergely Toldi
    Research Group of Pediatrics and Nephrology, Hungarian Academy of Sciences, Budapest, Hungary
    Acta Obstet Gynecol Scand 87:1229-33. 2008
    ..Low Treg numbers are not reflected in the proportion of activated lymphocytes, at least in this stage of pregnancy. This does not exclude, however, the functional alterations of these cell types...
  24. doi request reprint Decreased proportion of peripheral blood vascular endothelial growth factor-expressing T and natural killer cells in preeclampsia
    Attila Molvarec
    First Department of Obstetrics and Gynecology, Semmelweis University, Budapest, Hungary
    Am J Obstet Gynecol 203:567.e1-8. 2010
    ....
  25. doi request reprint Changes in serum cytokine and cortisol levels in normothermic and hypothermic term neonates after perinatal asphyxia
    Aniko Roka
    First Department of Pediatrics, Semmelweis University, Bokay u 53, Budapest, Hungary
    Inflamm Res 62:81-7. 2013
    ..Therapeutic hypothermia improves neurological outcome in asphyxiated term neonates, but its clear effect on the inflammatory response is unknown...
  26. doi request reprint In vivo confocal microscopic evaluation of corneal Langerhans cell density, and distribution and evaluation of dry eye in rheumatoid arthritis
    László Marsovszky
    Department of Ophthalmology, Semmelweis University, Budapest, Hungary
    Innate Immun 19:348-54. 2013
    ..The results also indicate ocular effects of GCS therapy in RA. ..