Pierre Theroux

Summary

Publications

  1. ncbi request reprint Perspectives on acute coronary syndromes
    Pierre Theroux
    Montreal Heart Institute, University of Montreal, Quebec
    Can J Cardiol 21:1053-60. 2005
  2. ncbi request reprint Prognostic significance of blood markers of inflammation in patients with ST-segment elevation myocardial infarction undergoing primary angioplasty and effects of pexelizumab, a C5 inhibitor: a substudy of the COMMA trial
    Pierre Theroux
    Montreal Heart Institute, Montreal, 5000 Belanger E, Montreal, Quebec, Canada H1T 1C8
    Eur Heart J 26:1964-70. 2005
  3. ncbi request reprint Matching the evaluation of the clinical efficacy of clopidogrel to platelet function tests relevant to the biological properties of the drug
    Benoit Labarthe
    Department of Medicine, Montreal Heart Institute and University of Montreal, Montreal, Quebec, Canada
    J Am Coll Cardiol 46:638-45. 2005
  4. doi request reprint Pexelizumab fails to inhibit assembly of the terminal complement complex in patients with ST-elevation myocardial infarction undergoing primary percutaneous coronary intervention. Insight from a substudy of the Assessment of Pexelizumab in Acute Myocardia
    Catherine Martel
    Department of Medicine, Montreal Heart Institute, Quebec, Canada
    Am Heart J 164:43-51. 2012
  5. ncbi request reprint Evaluation and risk stratification of acute coronary syndromes using a low cut-off level of cardiac troponin T, combined with CK-MB mass determination
    B Charles Solymoss
    Research Center, Montreal Heart Institute, Montreal, QC, Canada
    Clin Biochem 37:286-92. 2004
  6. ncbi request reprint Meta-analysis of randomized trials comparing enoxaparin versus unfractionated heparin as adjunctive therapy to fibrinolysis in ST-elevation acute myocardial infarction
    Pierre Theroux
    Department of Medicine, Montreal Heart Institute, University of Montreal, Montreal, Quebec, Canada
    Am J Cardiol 91:860-4. 2003
  7. pmc Requirements for membrane attack complex formation and anaphylatoxins binding to collagen-activated platelets
    Catherine Martel
    Department of Medicine, Montreal Heart Institute and University of Montreal, Montreal, Quebec, Canada
    PLoS ONE 6:e18812. 2011
  8. pmc Coping with new challenges in acute coronary syndromes
    Pierre Theroux
    Montreal Heart Institute and University of Montreal, Montreal, Quebec
    Can J Cardiol 22:13C-20C. 2006
  9. ncbi request reprint Comparison of primary percutaneous coronary intervention and fibrinolytic therapy in ST-segment-elevation myocardial infarction: bayesian hierarchical meta-analyses of randomized controlled trials and observational studies
    Thao Huynh
    1650 Ave Cedar, Room E 5200, Montreal, Quebec, H3G 1A4, Canada
    Circulation 119:3101-9. 2009
  10. pmc Endothelial progenitor cells bind and inhibit platelet function and thrombus formation
    Haissam Abou-Saleh
    Research Center, Montreal Heart Institute and Universite de Montreal, Faculty of Medicine, Montreal, Quebec, Canada, H1T 1C8
    Circulation 120:2230-9. 2009

Collaborators

Detail Information

Publications19

  1. ncbi request reprint Perspectives on acute coronary syndromes
    Pierre Theroux
    Montreal Heart Institute, University of Montreal, Quebec
    Can J Cardiol 21:1053-60. 2005
    ..New therapeutic frontiers are thus being suggested to control the most fundamental mechanisms involved in ACSs and related to inflammation and autoimmunity...
  2. ncbi request reprint Prognostic significance of blood markers of inflammation in patients with ST-segment elevation myocardial infarction undergoing primary angioplasty and effects of pexelizumab, a C5 inhibitor: a substudy of the COMMA trial
    Pierre Theroux
    Montreal Heart Institute, Montreal, 5000 Belanger E, Montreal, Quebec, Canada H1T 1C8
    Eur Heart J 26:1964-70. 2005
    ..Inflammation is a critical component of ST-elevation myocardial infarction (STEMI); this substudy examines prognostic values of selected markers and treatment effects...
  3. ncbi request reprint Matching the evaluation of the clinical efficacy of clopidogrel to platelet function tests relevant to the biological properties of the drug
    Benoit Labarthe
    Department of Medicine, Montreal Heart Institute and University of Montreal, Montreal, Quebec, Canada
    J Am Coll Cardiol 46:638-45. 2005
    ..This study aimed to explore platelet function tests relevant to the biological effects of clopidogrel that could help the clinical monitoring of drug efficacy...
  4. doi request reprint Pexelizumab fails to inhibit assembly of the terminal complement complex in patients with ST-elevation myocardial infarction undergoing primary percutaneous coronary intervention. Insight from a substudy of the Assessment of Pexelizumab in Acute Myocardia
    Catherine Martel
    Department of Medicine, Montreal Heart Institute, Quebec, Canada
    Am Heart J 164:43-51. 2012
    ..In a substudy of the APEX-AMI trial, we explored the hypothesis that early complement activation preceding drug administration explained the failure...
  5. ncbi request reprint Evaluation and risk stratification of acute coronary syndromes using a low cut-off level of cardiac troponin T, combined with CK-MB mass determination
    B Charles Solymoss
    Research Center, Montreal Heart Institute, Montreal, QC, Canada
    Clin Biochem 37:286-92. 2004
    ..To study the usefulness of combined cardiac Troponin T (cTnT) and CK-MB mass determinations in risk stratification of acute coronary syndromes...
  6. ncbi request reprint Meta-analysis of randomized trials comparing enoxaparin versus unfractionated heparin as adjunctive therapy to fibrinolysis in ST-elevation acute myocardial infarction
    Pierre Theroux
    Department of Medicine, Montreal Heart Institute, University of Montreal, Montreal, Quebec, Canada
    Am J Cardiol 91:860-4. 2003
  7. pmc Requirements for membrane attack complex formation and anaphylatoxins binding to collagen-activated platelets
    Catherine Martel
    Department of Medicine, Montreal Heart Institute and University of Montreal, Montreal, Quebec, Canada
    PLoS ONE 6:e18812. 2011
    ..The activation of complement during platelet activation is incompletely understood. Objectives: We sought to explore the formation of C5b-9 and anaphylatoxins binding to collagen-activated platelets...
  8. pmc Coping with new challenges in acute coronary syndromes
    Pierre Theroux
    Montreal Heart Institute and University of Montreal, Montreal, Quebec
    Can J Cardiol 22:13C-20C. 2006
    ....
  9. ncbi request reprint Comparison of primary percutaneous coronary intervention and fibrinolytic therapy in ST-segment-elevation myocardial infarction: bayesian hierarchical meta-analyses of randomized controlled trials and observational studies
    Thao Huynh
    1650 Ave Cedar, Room E 5200, Montreal, Quebec, H3G 1A4, Canada
    Circulation 119:3101-9. 2009
    ..We aim to obviate the limited applicability of RCTs to real-world settings by undertaking meta-analyses of both RCTs and observational studies...
  10. pmc Endothelial progenitor cells bind and inhibit platelet function and thrombus formation
    Haissam Abou-Saleh
    Research Center, Montreal Heart Institute and Universite de Montreal, Faculty of Medicine, Montreal, Quebec, Canada, H1T 1C8
    Circulation 120:2230-9. 2009
    ..Herein, we addressed the interactions between EPCs and platelets and their impact on platelet function and thrombus formation...
  11. pmc Demographics, treatment and outcome of acute coronary syndromes: 17 years of experience in a specialized cardiac centre
    Jean Pierre S Awaida
    Research Centre, Montreal Heart Institute, and Department of Medicine, University of Montreal, Quebec, Canada
    Can J Cardiol 22:121-4. 2006
    ..Epidemiological information on patients with acute coronary syndromes managed in specialized cardiac centres is limited...
  12. doi request reprint The pre-hospital fibrinolysis experience in Europe and North America and implications for wider dissemination
    Thao Huynh
    Division of Cardiology, Department of Medicine, McGill Health University Center, Montreal, Quebec, Canada
    JACC Cardiovasc Interv 4:877-83. 2011
    ..A secondary objective is to report the outcome data of the PHL programs surveyed...
  13. ncbi request reprint Classification and risk stratification of patients with acute chest pain using a low discriminatory level of cardiac troponin T
    B Charles Solymoss
    Department of Laboratory Medicine, Montreal Heart Institute, Montreal, Quebec, Canada
    Clin Cardiol 27:130-6. 2004
    ..20 or 0.10 microg/l cardiac troponin T (cTnT) levels. With the highly sensitive and specific second- and third-generation assays, cTnT is undetectable in most healthy individuals...
  14. doi request reprint Clopidogrel 600-mg double loading dose achieves stronger platelet inhibition than conventional regimens: results from the PREPAIR randomized study
    Philippe L L'Allier
    Department of Medicine, Montreal Heart Institute and Universite de Montreal, Montreal, Quebec, Canada
    J Am Coll Cardiol 51:1066-72. 2008
    ..The objective of this study was to compare the level of platelet inhibition achieved by 3 different clopidogrel loading regimens in patients undergoing elective angiography and percutaneous coronary intervention when appropriate...
  15. ncbi request reprint Clopidogrel inhibits platelet-leukocyte interactions and thrombin receptor agonist peptide-induced platelet activation in patients with an acute coronary syndrome
    Zihui Xiao
    Department of Medicine, Montreal Heart Institute, and University of Montreal, Montreal, Quebec, Canada
    J Am Coll Cardiol 43:1982-8. 2004
    ....
  16. pmc Complement activity and pharmacological inhibition in cardiovascular disease
    Pierre Theroux
    University of Montreal, Montreal, Quebec
    Can J Cardiol 22:18B-24B. 2006
    ....
  17. ncbi request reprint Analysis of bleeding complications associated with glycoprotein IIb/IIIa receptors blockade in patients with high-risk acute coronary syndromes: insights from the PRISM-PLUS study
    Thao Huynh
    Montreal General Hospital, McGill University Health Center, 1650 Cedar Avenue, Room E 5200, Montreal, Quebec, Canada H3G 1A4
    Int J Cardiol 100:73-8. 2005
    ....
  18. ncbi request reprint Effect of inhibition of the Na+/H+ exchanger with cariporide on left ventricular function in acute coronary syndromes: results from the echocardiographic substudy of the GUARDIAN trial
    Jean Claude Tardif
    Department of Medicine, Montreal Heart Institute, Montreal, Quebec
    Can J Cardiol 20:317-22. 2004
    ....
  19. ncbi request reprint A score predicts failure of reperfusion after fibrinolytic therapy for acute myocardial infarction
    John K French
    Cardiology Department, Green Lane Hospital, Auckland, New Zealand, Montreal Heart Institute, Montreal, Quebec, Canada
    Am Heart J 145:508-14. 2003
    ....