Si Wang

Summary

Affiliation: Wageningen University
Country: The Netherlands

Publications

  1. ncbi A 155-plex high-throughput in vitro coregulator binding assay for (anti-)estrogenicity testing evaluated with 23 reference compounds
    Si Wang
    Division of Toxicology, Wageningen University and Research Centre, Wageningen, The Netherlands
    ALTEX 30:145-57. 2013
  2. doi A low-density DNA microchip for the detection of (anti-)estrogenic compounds and their relative potencies
    Si Wang
    Division of Toxicology, Wageningen University and Research Centre, 6703 HE Wageningen, The Netherlands
    Anal Biochem 435:83-92. 2013
  3. doi Proliferation assays for estrogenicity testing with high predictive value for the in vivo uterotrophic effect
    Si Wang
    Division of Toxicology, Wageningen University and Research Centre, Tuinlaan 5, 6703 HE Wageningen, The Netherlands
    J Steroid Biochem Mol Biol 128:98-106. 2012
  4. doi Identification of coregulators influenced by estrogen receptor subtype specific binding of the ER antagonists 4-hydroxytamoxifen and fulvestrant
    Nynke M Evers
    Division of Toxicology, Wageningen University, Tuinlaan 5, 6703 HE Wageningen, The Netherlands Electronic address
    Chem Biol Interact 220:222-30. 2014
  5. doi Robust array-based coregulator binding assay predicting ERα-agonist potency and generating binding profiles reflecting ligand structure
    Jac M M J G Aarts
    Business Unit of Toxicology and Bioassays, RIKILT Institute of Food Safety, Wageningen University and Research Centre, Akkermaalsbos 2, Wageningen, The Netherlands
    Chem Res Toxicol 26:336-46. 2013
  6. doi Cell proliferation and modulation of interaction of estrogen receptors with coregulators induced by ERα and ERβ agonists
    Nynke M Evers
    Division of Toxicology, Wageningen University, Tuinlaan 5, 6703 HE Wageningen, The Netherlands Electronic address
    J Steroid Biochem Mol Biol 143:376-85. 2014
  7. doi Extending an in vitro panel for estrogenicity testing: the added value of bioassays for measuring antiandrogenic activities and effects on steroidogenesis
    Si Wang
    Division of Toxicology, Wageningen University and Research Centre, Tuinlaan 5, 6703 HE Wageningen, The Netherlands Business Unit of Toxicology and Bioassays, RIKILT Institute of Food Safety, Wageningen University and Research Centre, Akkermaalsbos 2, 6708 WB Wageningen, The Netherlands
    Toxicol Sci 141:78-89. 2014
  8. doi Towards an integrated in vitro strategy for estrogenicity testing
    Si Wang
    Division of Toxicology, Wageningen University and Research Centre, Tuinlaan 5, 6703 HE, Wageningen, The Netherlands Business Unit of Toxicology and Bioassays, RIKILT Institute of Food Safety, Wageningen University and Research Centre, Akkermaalsbos 2, 6708 WB, Wageningen, The Netherlands
    J Appl Toxicol 34:1031-40. 2014
  9. doi Detection of anabolic steroids in dietary supplements: the added value of an androgen yeast bioassay in parallel with a liquid chromatography-tandem mass spectrometry screening method
    Jeroen C W Rijk
    RIKILT Institute of Food Safety, Wageningen UR, P O Box 230, 6700 AE Wageningen, The Netherlands
    Anal Chim Acta 637:305-14. 2009

Collaborators

Detail Information

Publications9

  1. ncbi A 155-plex high-throughput in vitro coregulator binding assay for (anti-)estrogenicity testing evaluated with 23 reference compounds
    Si Wang
    Division of Toxicology, Wageningen University and Research Centre, Wageningen, The Netherlands
    ALTEX 30:145-57. 2013
    ....
  2. doi A low-density DNA microchip for the detection of (anti-)estrogenic compounds and their relative potencies
    Si Wang
    Division of Toxicology, Wageningen University and Research Centre, 6703 HE Wageningen, The Netherlands
    Anal Biochem 435:83-92. 2013
    ..It is concluded that low-density DNA microchip-based fingerprinting in MCF-7/BOS cells for estrogenicity marker genes provides a faster in vitro alternative to the current MCF-7/BOS cell proliferation assay (E-screen)...
  3. doi Proliferation assays for estrogenicity testing with high predictive value for the in vivo uterotrophic effect
    Si Wang
    Division of Toxicology, Wageningen University and Research Centre, Tuinlaan 5, 6703 HE Wageningen, The Netherlands
    J Steroid Biochem Mol Biol 128:98-106. 2012
    ..It is concluded that of the four cell lines tested, the best assay to include in an integrated testing strategy for replacement of the in vivo uterotrophic assay is the human MCF-7/BOS breast cancer cell line...
  4. doi Identification of coregulators influenced by estrogen receptor subtype specific binding of the ER antagonists 4-hydroxytamoxifen and fulvestrant
    Nynke M Evers
    Division of Toxicology, Wageningen University, Tuinlaan 5, 6703 HE Wageningen, The Netherlands Electronic address
    Chem Biol Interact 220:222-30. 2014
    ....
  5. doi Robust array-based coregulator binding assay predicting ERα-agonist potency and generating binding profiles reflecting ligand structure
    Jac M M J G Aarts
    Business Unit of Toxicology and Bioassays, RIKILT Institute of Food Safety, Wageningen University and Research Centre, Akkermaalsbos 2, Wageningen, The Netherlands
    Chem Res Toxicol 26:336-46. 2013
    ....
  6. doi Cell proliferation and modulation of interaction of estrogen receptors with coregulators induced by ERα and ERβ agonists
    Nynke M Evers
    Division of Toxicology, Wageningen University, Tuinlaan 5, 6703 HE Wageningen, The Netherlands Electronic address
    J Steroid Biochem Mol Biol 143:376-85. 2014
    ....
  7. doi Extending an in vitro panel for estrogenicity testing: the added value of bioassays for measuring antiandrogenic activities and effects on steroidogenesis
    Si Wang
    Division of Toxicology, Wageningen University and Research Centre, Tuinlaan 5, 6703 HE Wageningen, The Netherlands Business Unit of Toxicology and Bioassays, RIKILT Institute of Food Safety, Wageningen University and Research Centre, Akkermaalsbos 2, 6708 WB Wageningen, The Netherlands
    Toxicol Sci 141:78-89. 2014
    ..It was concluded that the extended ITS will go beyond in vivo estrogenicity testing by the uterotrophic assay, thereby contributing to the 3R-principles. ..
  8. doi Towards an integrated in vitro strategy for estrogenicity testing
    Si Wang
    Division of Toxicology, Wageningen University and Research Centre, Tuinlaan 5, 6703 HE, Wageningen, The Netherlands Business Unit of Toxicology and Bioassays, RIKILT Institute of Food Safety, Wageningen University and Research Centre, Akkermaalsbos 2, 6708 WB, Wageningen, The Netherlands
    J Appl Toxicol 34:1031-40. 2014
    ....
  9. doi Detection of anabolic steroids in dietary supplements: the added value of an androgen yeast bioassay in parallel with a liquid chromatography-tandem mass spectrometry screening method
    Jeroen C W Rijk
    RIKILT Institute of Food Safety, Wageningen UR, P O Box 230, 6700 AE Wageningen, The Netherlands
    Anal Chim Acta 637:305-14. 2009
    ....