Marcel Prins

Summary

Affiliation: Wageningen University
Country: The Netherlands

Publications

  1. ncbi request reprint Strategies for antiviral resistance in transgenic plants
    Marcel Prins
    Laboratory of Virology, Wageningen University, Binnenhaven 11, 6709 PD, Wageningen, The Netherlands
    Mol Plant Pathol 9:73-83. 2008
  2. pmc A novel class of heat-responsive small RNAs derived from the chloroplast genome of Chinese cabbage (Brassica rapa)
    Lu Wang
    National Key Laboratory of Plant Molecular Genetics, Institute of Plant Physiology and Ecology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, China
    BMC Genomics 12:289. 2011
  3. doi request reprint Potatovirus X and Tobacco mosaic virus-based vectors compatible with the Gateway cloning system
    Cristiano Lacorte
    Laboratory of Virology, Wageningen University, Wageningen, The Netherlands
    J Virol Methods 164:7-13. 2010
  4. pmc Tomato chlorotic mottle virus is a target of RNA silencing but the presence of specific short interfering RNAs does not guarantee resistance in transgenic plants
    Simone G Ribeiro
    Laboratory of Virology, Binnenhaven 11, 6709 PD Wageningen, The Netherlands
    J Virol 81:1563-73. 2007
  5. doi request reprint Binding of small interfering RNA molecules is crucial for RNA interference suppressor activity of rice hoja blanca virus NS3 in plants
    Hans Hemmes
    Laboratory of Virology, Wageningen University, Binnenhaven 11, 6709 PD Wageningen, The Netherlands
    J Gen Virol 90:1762-6. 2009
  6. ncbi request reprint Multiple virus resistance at a high frequency using a single transgene construct
    Etienne Bucher
    Laboratory of Virology, Wageningen University, Binnenhaven 11, 6709 PD Wageningen, The Netherlands
    J Gen Virol 87:3697-701. 2006
  7. pmc The NS3 protein of Rice hoja blanca tenuivirus suppresses RNA silencing in plant and insect hosts by efficiently binding both siRNAs and miRNAs
    Hans Hemmes
    Laboratory of Virology, Wageningen University, Wageningen, The Netherlands
    RNA 13:1079-89. 2007
  8. ncbi request reprint The influenza A virus NS1 protein binds small interfering RNAs and suppresses RNA silencing in plants
    Etienne Bucher
    Laboratory of Virology, Wageningen University, Binnenhaven 11, 6709 PD Wageningen, The Netherlands
    J Gen Virol 85:983-91. 2004
  9. pmc Diverging affinity of tospovirus RNA silencing suppressor proteins, NSs, for various RNA duplex molecules
    Esther Schnettler
    Wageningen University, Laboratory of Virology, Droevendaalsesteeg 1, 6708 PB Wageningen, Netherlands
    J Virol 84:11542-54. 2010
  10. ncbi request reprint The nucleoprotein of Tomato spotted wilt virus as protein tag for easy purification and enhanced production of recombinant proteins in plants
    Cristiano Lacorte
    Laboratory of Virology, Wageningen University, Binnenhaven 11, 6709 PD Wageningen, The Netherlands
    Protein Expr Purif 55:17-22. 2007

Collaborators

Detail Information

Publications17

  1. ncbi request reprint Strategies for antiviral resistance in transgenic plants
    Marcel Prins
    Laboratory of Virology, Wageningen University, Binnenhaven 11, 6709 PD, Wageningen, The Netherlands
    Mol Plant Pathol 9:73-83. 2008
    ..In a final summarizing section, the potential risks involved in the introduction of transgenic crops and the specifics of the approaches used will be discussed...
  2. pmc A novel class of heat-responsive small RNAs derived from the chloroplast genome of Chinese cabbage (Brassica rapa)
    Lu Wang
    National Key Laboratory of Plant Molecular Genetics, Institute of Plant Physiology and Ecology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, China
    BMC Genomics 12:289. 2011
    ....
  3. doi request reprint Potatovirus X and Tobacco mosaic virus-based vectors compatible with the Gateway cloning system
    Cristiano Lacorte
    Laboratory of Virology, Wageningen University, Wageningen, The Netherlands
    J Virol Methods 164:7-13. 2010
    ..A PVX-GW transient expression assay of a nucleocapsid protein gene fragment of Tomato spotted wilt virus and of a single chain antibody against this protein was shown to confer effective resistance to TSWV infection...
  4. pmc Tomato chlorotic mottle virus is a target of RNA silencing but the presence of specific short interfering RNAs does not guarantee resistance in transgenic plants
    Simone G Ribeiro
    Laboratory of Virology, Binnenhaven 11, 6709 PD Wageningen, The Netherlands
    J Virol 81:1563-73. 2007
    ....
  5. doi request reprint Binding of small interfering RNA molecules is crucial for RNA interference suppressor activity of rice hoja blanca virus NS3 in plants
    Hans Hemmes
    Laboratory of Virology, Wageningen University, Binnenhaven 11, 6709 PD Wageningen, The Netherlands
    J Gen Virol 90:1762-6. 2009
    ..This indicates that siRNA binding of NS3 is indeed essential for the suppressor function of NS3 and that residues at positions 173-175 are involved in the siRNA binding and suppressor activities...
  6. ncbi request reprint Multiple virus resistance at a high frequency using a single transgene construct
    Etienne Bucher
    Laboratory of Virology, Wageningen University, Binnenhaven 11, 6709 PD Wageningen, The Netherlands
    J Gen Virol 87:3697-701. 2006
    ..Thus RNA silencing can be further improved for high frequency multiple virus resistance by combining small RNA fragments from a series of target viruses...
  7. pmc The NS3 protein of Rice hoja blanca tenuivirus suppresses RNA silencing in plant and insect hosts by efficiently binding both siRNAs and miRNAs
    Hans Hemmes
    Laboratory of Virology, Wageningen University, Wageningen, The Netherlands
    RNA 13:1079-89. 2007
    ..In addition, NS3 has a high affinity for miRNA/miRNA* duplexes, indicating that its activity might also interfere with miRNA-regulated gene expression in both insects and plants...
  8. ncbi request reprint The influenza A virus NS1 protein binds small interfering RNAs and suppresses RNA silencing in plants
    Etienne Bucher
    Laboratory of Virology, Wageningen University, Binnenhaven 11, 6709 PD Wageningen, The Netherlands
    J Gen Virol 85:983-91. 2004
    ..In addition, NS1 was shown to be capable of binding siRNAs. The data presented here fit with a potential role for NS1 in counteracting innate antiviral responses in vertebrates by sequestering siRNAs...
  9. pmc Diverging affinity of tospovirus RNA silencing suppressor proteins, NSs, for various RNA duplex molecules
    Esther Schnettler
    Wageningen University, Laboratory of Virology, Droevendaalsesteeg 1, 6708 PB Wageningen, Netherlands
    J Virol 84:11542-54. 2010
    ..The observed affinity to long dsRNA for only a subset of the tospoviruses studied is discussed in light of evolutional divergence and their ancestral relation to the animal-infecting members of the Bunyaviridae...
  10. ncbi request reprint The nucleoprotein of Tomato spotted wilt virus as protein tag for easy purification and enhanced production of recombinant proteins in plants
    Cristiano Lacorte
    Laboratory of Virology, Wageningen University, Binnenhaven 11, 6709 PD Wageningen, The Netherlands
    Protein Expr Purif 55:17-22. 2007
    ..These results show that the homopolymerization properties of the N protein can be used as a fast and simple way to purify large amounts of proteins from plants...
  11. ncbi request reprint Assessing the expression of chicken anemia virus proteins in plants
    Cristiano Lacorte
    Laboratory of Virology, Wageningen University, Binnenhaven 11, 6709 PD Wageningen, The Netherlands
    Virus Res 129:80-6. 2007
    ..Overall, our results show that all CAV proteins can be expressed in plant cells, though expression level of VP1 needs to be further optimized before testing its potential as (edible) subunit vaccine...
  12. ncbi request reprint Resistance mechanisms to plant viruses: an overview
    Rob Goldbach
    Laboratory of Virology, Wageningen University, Binnenhaven 11, PD 6709 Wageningen, The Netherlands
    Virus Res 92:207-12. 2003
    ..This paper will give a brief overview of the major strategies that have become operational during the past 10 years...
  13. ncbi request reprint Broad virus resistance in transgenic plants
    Marcel Prins
    Laboratory of Virology, Wageningen University, Binnenhaven 11, 6709 PD Wageningen, The Netherlands
    Trends Biotechnol 21:373-5. 2003
    ..Increased understanding of the molecular biology of virus infection is starting to bear fruit, enabling specific strategies to be designed for virus resistance in crops...
  14. ncbi request reprint The NS3 protein of rice hoja blanca virus suppresses RNA silencing in mammalian cells
    Esther Schnettler
    Laboratory of Virology, Wageningen University, Binnenhaven 11, 6709 PD Wageningen, The Netherlands
    J Gen Virol 89:336-40. 2008
    ..The possible applications of this protein in modulating RNAi and investigating the proposed antiviral RNAi response in mammalian cell systems are discussed...
  15. ncbi request reprint Phage display-selected single-chain antibodies confer high levels of resistance against Tomato spotted wilt virus
    Marcel Prins
    Laboratory of Virology, Wageningen University, The Netherlands
    J Gen Virol 86:2107-13. 2005
    ..Protoplast experiments provided evidence that the two resistance-conferring antibodies may have a different mode of action and could be combined for higher durability of resistance in the field...
  16. pmc Negative-strand tospoviruses and tenuiviruses carry a gene for a suppressor of gene silencing at analogous genomic positions
    Etienne Bucher
    Laboratory of Virology, Wageningen University, The Netherlands
    J Virol 77:1329-36. 2003
    ..These results indicate that plant-infecting negative-strand RNA viruses carry a gene for a suppressor of RNA silencing...
  17. pmc Inter- and intramolecular recombinations in the cucumber mosaic virus genome related to adaptation to alstroemeria
    Yuh Kun Chen
    Laboratory of Virology, Wageningen University, Wageningen, The Netherlands
    J Virol 76:4119-24. 2002
    ..Competition experiments revealed that these recombined RNA 2 and 3 segments increased the biological fitness of CMV in alstroemeria...