Research Topics
| I A T M MeertsSummaryAffiliation: Wageningen University Country: The Netherlands Publications
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Detail Information
Publications
In vitro estrogenicity of polybrominated diphenyl ethers, hydroxylated PDBEs, and polybrominated bisphenol A compoundsI A Meerts
Toxicology Group, Wageningen University and Research Center, Wageningen, The Netherlands
Environ Health Perspect 109:399-407. 2001..These data also suggest that in vivo metabolism of PBDEs may produce more potent pseudoestrogens...
Placental transfer of a hydroxylated polychlorinated biphenyl and effects on fetal and maternal thyroid hormone homeostasis in the ratIlonka A T M Meerts
Toxicology Group, Wageningen University and Research Center, Tuinlaan 5, 6703 HE Wageningen, The Netherlands
Toxicol Sci 68:361-71. 2002..Consequently, TT(4) levels in fetal plasma and brain samples were reduced. Despite reductions in fetal brain T(4) levels, the active hormone (T(3)) in fetal brains remained unaffected...
Effects of in utero exposure to 4-hydroxy-2,3,3',4',5-pentachlorobiphenyl (4-OH-CB107) on developmental landmarks, steroid hormone levels, and female estrous cyclicity in ratsIlonka A T M Meerts
Toxicology Group, Wageningen University, Wageningen, The Netherlands
Toxicol Sci 82:259-67. 2004..These results indicate that in utero exposure to 4-OH-CB107 leads to endocrine-disrupting effects, especially in female offspring. The possible impact on neurobehavior following exposure to 4-OH-CB107 will be reported elsewhere...
Developmental exposure to 4-hydroxy-2,3,3',4',5-pentachlorobiphenyl (4-OH-CB107): long-term effects on brain development, behavior, and brain stem auditory evoked potentials in ratsIlonka A T M Meerts
Toxicology Group, Wageningen University and Research Center, 6703 HE Wageningen, The Netherlands
Toxicol Sci 82:207-18. 2004..The observed effects for 4-OH-CB107 are similar to, but in some aspects different from, the effects observed after Aroclor 1254 exposure...
Toxicological evaluation of pomegranate seed oilI A T M Meerts
Department of In vitro and Environmental Toxicology, NOTOX B V, Hambakenwetering 7, 5231 DD s Hertogenbosch, The Netherlands
Food Chem Toxicol 47:1085-92. 2009..The no observable adverse effect level (NOAEL) was 50,000 ppm PSO (=4.3 g PSO/kg body weight/day)...
An alternative approach for the safety evaluation of new and existing chemicals, an exercise in integrated testingW M L G Gubbels-van Hal
NOTOX B V, 5203 DL s Hertogenbosch, The Netherlands
Regul Toxicol Pharmacol 42:284-95. 2005..This integrated approach leads to a 38% reduction of laboratory animals...
