Thijs J G Ettema

Summary

Affiliation: Wageningen University
Country: The Netherlands

Publications

  1. ncbi request reprint TRASH: a novel metal-binding domain predicted to be involved in heavy-metal sensing, trafficking and resistance
    Thijs J G Ettema
    Laboratory of Microbiology, Wageningen University and Research Center Hesselink van Suchtelenweg 4, NL 6703CT, Wageningen, The Netherlands
    Trends Biochem Sci 28:170-3. 2003
  2. pmc Identification and functional verification of archaeal-type phosphoenolpyruvate carboxylase, a missing link in archaeal central carbohydrate metabolism
    Thijs J G Ettema
    Laboratory of Microbiology, Agrotechnology and Food Sciences, Wageningen University, Wageningen, The Netherlands
    J Bacteriol 186:7754-62. 2004
  3. ncbi request reprint The Lrp family of transcriptional regulators
    Arie B Brinkman
    Laboratory of Microbiology, Wageningen University, Hesselink van Suchtelenweg 4, NL 6307 CT Wageningen, The Netherlands
    Mol Microbiol 48:287-94. 2003
  4. ncbi request reprint Discovering novel biology by in silico archaeology
    Thijs J G Ettema
    Laboratory of Microbiology, Wageningen University, 6703 CT Wageningen, The Netherlands
    Nat Rev Microbiol 3:859-69. 2005
  5. ncbi request reprint A novel ligand-binding domain involved in regulation of amino acid metabolism in prokaryotes
    Thijs J G Ettema
    Laboratory of Microbiology, Wageningen University, Hesselink van Suchtelenweg 4, NL 6307 CT Wageningen, The Netherlands
    J Biol Chem 277:37464-8. 2002
  6. ncbi request reprint Molecular characterization of a conserved archaeal copper resistance (cop) gene cluster and its copper-responsive regulator in Sulfolobus solfataricus P2
    Thijs J G Ettema
    Laboratory of Microbiology, Wageningen University, Hesselink van Suchtelenweg 4, The Netherlands
    Microbiology 152:1969-79. 2006
  7. pmc Biochemical adaptations of two sugar kinases from the hyperthermophilic archaeon Pyrococcus furiosus
    Corne H Verhees
    Laboratory of Microbiology, Department of Agrotechnology and Food Sciences, Wageningen University, The Netherlands
    Biochem J 366:121-7. 2002
  8. ncbi request reprint The non-phosphorylating glyceraldehyde-3-phosphate dehydrogenase (GAPN) of Sulfolobus solfataricus: a key-enzyme of the semi-phosphorylative branch of the Entner-Doudoroff pathway
    Thijs J G Ettema
    Department of Molecular Evolution, Evolutionary Biology Center, Uppsala University, Norbyvagen 18C, 752 36 Uppsala, Sweden
    Extremophiles 12:75-88. 2008
  9. pmc Reconstructing the evolution of the mitochondrial ribosomal proteome
    Paulien Smits
    Nijmegen Center for Mitochondrial Disorders, Radboud University Nijmegen Medical Center, Geert Grooteplein zuid 10, Nijmegen, The Netherlands
    Nucleic Acids Res 35:4686-703. 2007
  10. pmc Signature genes as a phylogenomic tool
    Bas E Dutilh
    Center for Molecular and Biomolecular Informatics Nijmegen Center for Molecular Life Sciences, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    Mol Biol Evol 25:1659-67. 2008

Collaborators

Detail Information

Publications11

  1. ncbi request reprint TRASH: a novel metal-binding domain predicted to be involved in heavy-metal sensing, trafficking and resistance
    Thijs J G Ettema
    Laboratory of Microbiology, Wageningen University and Research Center Hesselink van Suchtelenweg 4, NL 6703CT, Wageningen, The Netherlands
    Trends Biochem Sci 28:170-3. 2003
    ..The role of the multiple copies of TRASH that are present in vertebrate proteins remains to be elucidated...
  2. pmc Identification and functional verification of archaeal-type phosphoenolpyruvate carboxylase, a missing link in archaeal central carbohydrate metabolism
    Thijs J G Ettema
    Laboratory of Microbiology, Agrotechnology and Food Sciences, Wageningen University, Wageningen, The Netherlands
    J Bacteriol 186:7754-62. 2004
    ..The newly identified atPEPC, with its distinct properties, constitutes yet another example of the versatility of the enzymes of the central carbon metabolic pathways in the archaeal domain...
  3. ncbi request reprint The Lrp family of transcriptional regulators
    Arie B Brinkman
    Laboratory of Microbiology, Wageningen University, Hesselink van Suchtelenweg 4, NL 6307 CT Wageningen, The Netherlands
    Mol Microbiol 48:287-94. 2003
    ....
  4. ncbi request reprint Discovering novel biology by in silico archaeology
    Thijs J G Ettema
    Laboratory of Microbiology, Wageningen University, 6703 CT Wageningen, The Netherlands
    Nat Rev Microbiol 3:859-69. 2005
    ..Combined with experimental verification, bioinformatic analysis contributes to the ongoing discovery of novel metabolic conversions and control mechanisms, and as such to a better understanding of the intriguing biology of the Archaea...
  5. ncbi request reprint A novel ligand-binding domain involved in regulation of amino acid metabolism in prokaryotes
    Thijs J G Ettema
    Laboratory of Microbiology, Wageningen University, Hesselink van Suchtelenweg 4, NL 6307 CT Wageningen, The Netherlands
    J Biol Chem 277:37464-8. 2002
    ..Both domains appear to play analogous roles in controlling key steps in amino acid metabolism at the level of gene expression as well as enzyme activity...
  6. ncbi request reprint Molecular characterization of a conserved archaeal copper resistance (cop) gene cluster and its copper-responsive regulator in Sulfolobus solfataricus P2
    Thijs J G Ettema
    Laboratory of Microbiology, Wageningen University, Hesselink van Suchtelenweg 4, The Netherlands
    Microbiology 152:1969-79. 2006
    ..A model is proposed for copper-responsive transcriptional regulation of the copMA gene cluster...
  7. pmc Biochemical adaptations of two sugar kinases from the hyperthermophilic archaeon Pyrococcus furiosus
    Corne H Verhees
    Laboratory of Microbiology, Department of Agrotechnology and Food Sciences, Wageningen University, The Netherlands
    Biochem J 366:121-7. 2002
    ..There is a discussion about whether the unusual features of these two classes of kinases might reflect adaptations to a relatively low intracellular ATP concentration in the hyperthermophilic archaeon P. furiosus...
  8. ncbi request reprint The non-phosphorylating glyceraldehyde-3-phosphate dehydrogenase (GAPN) of Sulfolobus solfataricus: a key-enzyme of the semi-phosphorylative branch of the Entner-Doudoroff pathway
    Thijs J G Ettema
    Department of Molecular Evolution, Evolutionary Biology Center, Uppsala University, Norbyvagen 18C, 752 36 Uppsala, Sweden
    Extremophiles 12:75-88. 2008
    ..This work suggests an important role of GAPN in the regulation of carbon degradation via modifications of the EMP and the branched ED pathway in hyperthermophilic Archaea...
  9. pmc Reconstructing the evolution of the mitochondrial ribosomal proteome
    Paulien Smits
    Nijmegen Center for Mitochondrial Disorders, Radboud University Nijmegen Medical Center, Geert Grooteplein zuid 10, Nijmegen, The Netherlands
    Nucleic Acids Res 35:4686-703. 2007
    ..These newly detected MRPs constitute, along with evolutionary conserved MRPs, excellent new screening targets for human patients with unresolved mitochondrial oxidative phosphorylation disorders...
  10. pmc Signature genes as a phylogenomic tool
    Bas E Dutilh
    Center for Molecular and Biomolecular Informatics Nijmegen Center for Molecular Life Sciences, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    Mol Biol Evol 25:1659-67. 2008
    ..Summarizing, signature genes can complement traditional sequence-based methods in addressing taxonomic questions...
  11. doi request reprint Comment on "A 3-hydroxypropionate/4-hydroxybutyrate autotrophic carbon dioxide assimilation pathway in Archaea"
    Thijs J G Ettema
    Department of Molecular Evolution, Evolutionary Biology Centre, Uppsala University, Uppsala, S 752 36 Sweden
    Science 321:342; author reply 342. 2008
    ..We question the validity of the latter claim...