Ingeborg A Brouwer

Summary

Affiliation: Wageningen University
Country: The Netherlands

Publications

  1. ncbi request reprint Effect of fish oil on ventricular tachyarrhythmia and death in patients with implantable cardioverter defibrillators: the Study on Omega-3 Fatty Acids and Ventricular Arrhythmia (SOFA) randomized trial
    Ingeborg A Brouwer
    Wageningen Centre for Food Sciences, Division of Human Nutrition, Wageningen University, Wageningen, The Netherlands
    JAMA 295:2613-9. 2006
  2. ncbi request reprint n-3 Fatty acids, cardiac arrhythmia and fatal coronary heart disease
    Ingeborg A Brouwer
    Wageningen Centre for Food Sciences and Division of Human Nutrition, Wageningen University, Wageningen, The Netherlands
    Prog Lipid Res 45:357-67. 2006
  3. ncbi request reprint Intake of very long-chain n-3 fatty acids from fish and incidence of atrial fibrillation. The Rotterdam Study
    Ingeborg A Brouwer
    Wageningen Centre for Food Sciences, Wageningen, The Netherlands
    Am Heart J 151:857-62. 2006
  4. ncbi request reprint Dietary alpha-linolenic acid is associated with reduced risk of fatal coronary heart disease, but increased prostate cancer risk: a meta-analysis
    Ingeborg A Brouwer
    Wageningen Centre for Food Sciences, Wageningen, The Netherlands
    J Nutr 134:919-22. 2004
  5. doi request reprint Intake of very long chain n-3 fatty acids from fish and the incidence of heart failure: the Rotterdam Study
    S Coosje Dijkstra
    Division of Human Nutrition, Wageningen University, PO Box 8129, 6700 EV Wageningen, The Netherlands
    Eur J Heart Fail 11:922-8. 2009
  6. ncbi request reprint Effect of n-3 fatty acids from fish on electrocardiographic characteristics in patients with frequent premature ventricular complexes
    Anouk Geelen
    Wageningen Centre for Food Sciences WCFS and Division of Human Nutrition, Wageningen University, Wageningen, The Netherlands
    Br J Nutr 93:787-90. 2005
  7. ncbi request reprint Effects of n-3 fatty acids from fish on premature ventricular complexes and heart rate in humans
    Anouk Geelen
    Wageningen Centre for Food Sciences and Division of Human Nutrition, Wageningen University, Wageningen, Netherlands
    Am J Clin Nutr 81:416-20. 2005
  8. doi request reprint Intake of fish and marine n-3 fatty acids in relation to coronary calcification: the Rotterdam Study
    Renate C Heine-Bröring
    Division of Human Nutrition, Wageningen University, Wageningen, The Netherlands
    Am J Clin Nutr 91:1317-23. 2010
  9. pmc Effect of fish oil on ventricular tachyarrhythmia in three studies in patients with implantable cardioverter defibrillators
    Ingeborg A Brouwer
    TI Food and Nutrition, Wageningen, The Netherlands
    Eur Heart J 30:820-6. 2009
  10. ncbi request reprint Effect of n-3 fatty acids on heart rate variability and baroreflex sensitivity in middle-aged subjects
    Anouk Geelen
    Wageningen Centre for Food Sciences, Wageningen, The Netherlands
    Am Heart J 146:E4. 2003

Collaborators

Detail Information

Publications27

  1. ncbi request reprint Effect of fish oil on ventricular tachyarrhythmia and death in patients with implantable cardioverter defibrillators: the Study on Omega-3 Fatty Acids and Ventricular Arrhythmia (SOFA) randomized trial
    Ingeborg A Brouwer
    Wageningen Centre for Food Sciences, Division of Human Nutrition, Wageningen University, Wageningen, The Netherlands
    JAMA 295:2613-9. 2006
    ..Very-long-chain n-3 polyunsaturated fatty acids (omega-3 PUFAs) from fish are thought to reduce risk of sudden death, possibly by reducing susceptibility to cardiac arrhythmia...
  2. ncbi request reprint n-3 Fatty acids, cardiac arrhythmia and fatal coronary heart disease
    Ingeborg A Brouwer
    Wageningen Centre for Food Sciences and Division of Human Nutrition, Wageningen University, Wageningen, The Netherlands
    Prog Lipid Res 45:357-67. 2006
    ....
  3. ncbi request reprint Intake of very long-chain n-3 fatty acids from fish and incidence of atrial fibrillation. The Rotterdam Study
    Ingeborg A Brouwer
    Wageningen Centre for Food Sciences, Wageningen, The Netherlands
    Am Heart J 151:857-62. 2006
    ..The objective of this study was to examine whether high intakes of fish and its very long-chain n-3 fatty acids eicosapentaenoic acid (EPA) plus docosahexaenoic acid (DHA) are associated with risk of incident atrial fibrillation...
  4. ncbi request reprint Dietary alpha-linolenic acid is associated with reduced risk of fatal coronary heart disease, but increased prostate cancer risk: a meta-analysis
    Ingeborg A Brouwer
    Wageningen Centre for Food Sciences, Wageningen, The Netherlands
    J Nutr 134:919-22. 2004
    ..70; 95% CI 1.12-2.58). This meta-analysis shows that consumption of ALA might reduce heart disease mortality. However, the association between high intake of ALA and prostate cancer is of concern and warrants further study...
  5. doi request reprint Intake of very long chain n-3 fatty acids from fish and the incidence of heart failure: the Rotterdam Study
    S Coosje Dijkstra
    Division of Human Nutrition, Wageningen University, PO Box 8129, 6700 EV Wageningen, The Netherlands
    Eur J Heart Fail 11:922-8. 2009
    ..We examined EPA plus DHA and fish intake in relation to incident heart failure in the population-based Rotterdam Study...
  6. ncbi request reprint Effect of n-3 fatty acids from fish on electrocardiographic characteristics in patients with frequent premature ventricular complexes
    Anouk Geelen
    Wageningen Centre for Food Sciences WCFS and Division of Human Nutrition, Wageningen University, Wageningen, The Netherlands
    Br J Nutr 93:787-90. 2005
    ..However, we cannot exclude effects of n-3 fatty acids on clinical relevant endpoints that are not easily detected by prior changes in the ECG...
  7. ncbi request reprint Effects of n-3 fatty acids from fish on premature ventricular complexes and heart rate in humans
    Anouk Geelen
    Wageningen Centre for Food Sciences and Division of Human Nutrition, Wageningen University, Wageningen, Netherlands
    Am J Clin Nutr 81:416-20. 2005
    ..A large body of evidence suggests that n-3 fatty acids from fish prevent fatal heart disease. They may be an effective and safe alternative to drug treatment for reducing the risk of arrhythmia and sudden cardiac death...
  8. doi request reprint Intake of fish and marine n-3 fatty acids in relation to coronary calcification: the Rotterdam Study
    Renate C Heine-Bröring
    Division of Human Nutrition, Wageningen University, Wageningen, The Netherlands
    Am J Clin Nutr 91:1317-23. 2010
    ..Epidemiologic and experimental data suggest a cardioprotective effect of n-3 (omega-3) fatty acids from fish [eicosapentaenoic acid (EPA) plus docosahexaenoic acid (DHA)]...
  9. pmc Effect of fish oil on ventricular tachyarrhythmia in three studies in patients with implantable cardioverter defibrillators
    Ingeborg A Brouwer
    TI Food and Nutrition, Wageningen, The Netherlands
    Eur Heart J 30:820-6. 2009
    ....
  10. ncbi request reprint Effect of n-3 fatty acids on heart rate variability and baroreflex sensitivity in middle-aged subjects
    Anouk Geelen
    Wageningen Centre for Food Sciences, Wageningen, The Netherlands
    Am Heart J 146:E4. 2003
    ..Effects of n-3 fatty acids on these risk indicators of arrhythmia have not been widely studied. We investigated the effect of supplemental intake of n-3 fatty acids on HRV and BRS in apparently healthy subjects aged 50 to 70 years...
  11. doi request reprint Differences in fatty acid composition between cerebral brain lobes in juvenile pigs after fish oil feeding
    Carla Dullemeijer
    Top Institute Food and Nutrition, Wageningen, The Netherlands
    Br J Nutr 100:794-800. 2008
    ..The functional consequences of these differences are a challenging focus for future investigation...
  12. ncbi request reprint Antiarrhythmic effects of n-3 fatty acids: evidence from human studies
    Anouk Geelen
    Wageningen Centre for Food Sciences and Division of Human Nutrition, Wageningen University, Wageningen, The Netherlands
    Curr Opin Lipidol 15:25-30. 2004
    ..In this paper, the authors discuss the results of human studies with regard to the hypothesis that n-3 fatty acids reduce the risk of fatal coronary heart disease through antiarrhythmic effects...
  13. ncbi request reprint Lactotripeptides show no effect on human blood pressure: results from a double-blind randomized controlled trial
    Marielle F Engberink
    Wageningen University, Division of Human Nutrition, P O Box 8129, 6700 EV Wageningen, The Netherlands
    Hypertension 51:399-405. 2008
    ..In conclusion, the present study does not support the hypothesis of a blood pressure lowering effect of the lactotripeptides Isoleucine-Proline-Proline and Valine-Proline-Proline...
  14. ncbi request reprint Bioavailability of food folates is 80% of that of folic acid
    Renate M Winkels
    Wageningen Centre for Food Sciences, Wageningen, Netherlands
    Am J Clin Nutr 85:465-73. 2007
    ..The bioavailability of natural food folates is lower than that of synthetic folic acid, but no agreement exists as to the extent of the difference...
  15. pmc Alpha-linolenic acid: is it essential to cardiovascular health?
    Johanna M Geleijnse
    Division of Human Nutrition, Wageningen University, Wageningen, The Netherlands
    Curr Atheroscler Rep 12:359-67. 2010
    ..Findings from long-term trials of ALA supplementation are awaited to answer the question whether food-based or higher doses of ALA could be important for cardiovascular health in cardiac patients and the general population...
  16. ncbi request reprint Folic acid and reduction of plasma homocysteine concentrations in older adults: a dose-response study
    Floor V A van Oort
    Wageningen Centre for Food Sciences, Wageningen, Netherlands
    Am J Clin Nutr 77:1318-23. 2003
    ..The minimum dose of folic acid required for maximal reduction of homocysteine concentrations is not yet known reliably...
  17. ncbi request reprint n 3 fatty acid proportions in plasma and cognitive performance in older adults
    Carla Dullemeijer
    Wageningen Centre for Food Sciences, Wageningen, Netherlands
    Am J Clin Nutr 86:1479-85. 2007
    ..However, limited data exist on the association between n-3 PUFAs and performance in specific cognitive domains...
  18. ncbi request reprint Association between n-3 fatty acid status in blood and electrocardiographic predictors of arrhythmia risk in healthy volunteers
    Ingeborg A Brouwer
    Wageningen Centre for Food Sciences, Wageningen, The Netherlands
    Am J Cardiol 89:629-31. 2002
  19. ncbi request reprint Erythrocyte folate and plasma DHA in the FACIT study
    Carla Dullemeijer
    Lancet 370:216. 2007
  20. ncbi request reprint (N-3) fatty acids do not affect electrocardiographic characteristics of healthy men and women
    Anouk Geelen
    Wageningen Centre for Food Sciences WCFS, The Netherlands
    J Nutr 132:3051-4. 2002
    ..These results do not support the hypothesis that (n-3) fatty acids prevent arrhythmia through electrophysiologic effects on heart cell membranes. However, an effect on the ECG in more susceptible populations can not be excluded...
  21. ncbi request reprint Effect of fish oil on heart rate in humans: a meta-analysis of randomized controlled trials
    Dariush Mozaffarian
    Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
    Circulation 112:1945-52. 2005
    ..The effect of fish oil on heart rate (HR), a major risk factor for sudden death, is not well established. We calculated this effect in a meta-analysis of randomized, double-blind, placebo-controlled trials in humans...
  22. pmc Risks and benefits of omega 3 fats: health benefits of omega 3 fats are in doubt
    Johanna M Geleijnse
    BMJ 332:915; discussion 915-6. 2006
  23. ncbi request reprint Effects of n-3 fatty acids on arrhythmic events and mortality in the SOFA implantable cardioverter defibrillator trial
    Ingeborg A Brouwer
    Am J Clin Nutr 84:1554; author reply 1554-5. 2006
  24. doi request reprint Identification of potential serum biomarkers of inflammation and lipid modulation that are altered by fish oil supplementation in healthy volunteers
    Baukje de Roos
    Department of Vascular Health, Rowett Research Institute, Aberdeen, UK
    Proteomics 8:1965-74. 2008
    ..These proteins are potential diagnostic biomarkers to assess the mechanisms whereby fish oil protects against CHD in humans...
  25. ncbi request reprint Gender and body size affect the response of erythrocyte folate to folic acid treatment
    Renate M Winkels
    Top Institute Food and Nutrition, 6709PA Wageningen, The Netherlands
    J Nutr 138:1456-61. 2008
    ..This could be an indication that the RDA for folate should be higher for men than for women, or that the RDA should be expressed per kilogram of lean body mass...
  26. doi request reprint Acute administration of fish oil inhibits triggered activity in isolated myocytes from rabbits and patients with heart failure
    Hester M den Ruijter
    Department of Experimental Cardiology, Center for Heart Failure Research, Academic Medical Center, Room K2 113, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands
    Circulation 117:536-44. 2008
    ..We hypothesized that superfusion with omega3-polyunsaturated fatty acids (omega3-PUFAs) from fish inhibits triggered activity in heart failure...
  27. ncbi request reprint Bread cofortified with folic acid and vitamin B-12 improves the folate and vitamin B-12 status of healthy older people: a randomized controlled trial
    Renate M Winkels
    Top Institute of Food and Nutrition, Wageningen, Netherlands
    Am J Clin Nutr 88:348-55. 2008
    ..Cofortification of flour with folic acid and vitamin B-12 could simultaneously improve folate and vitamin B-12 status...