Research Topics
| Raoul J BinoSummaryAffiliation: Wageningen University Country: The Netherlands Publications
| Collaborators
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Detail Information
Publications
A novel approach for nontargeted data analysis for metabolomics. Large-scale profiling of tomato fruit volatilesYury Tikunov
Centre for BioSystems Genomics, 6700 AB Wageningen, The Netherlands
Plant Physiol 139:1125-37. 2005..The approach chosen will further enhance the comprehensiveness of GC-MS-based metabolomics approaches and will therefore prove a useful addition to nontargeted functional genomics research...
Potential of metabolomics as a functional genomics toolRaoul J Bino
Plant Physiology Department, Wageningen University, Arboretumlaan 4, 6703 BD Wageningen, The Netherlands
Trends Plant Sci 9:418-25. 2004- The light-hyperresponsive high pigment-2dg mutation of tomato: alterations in the fruit metabolomeRaoul J Bino
Plant Research International, POB 16, 6700 AA Wageningen, The Netherlands
New Phytol 166:427-38. 2005..The similarity in metabolic alterations in fruits of hp-1 and hp-2 mutant plants helps us to understand how hp mutations affect cellular processes... - Tissue specialization at the metabolite level is perceived during the development of tomato fruitSofia Moco
Laboratory of Biochemistry, Wageningen University, Dreijenlaan 3, 6703 HA, Wageningen, The Netherlands
J Exp Bot 58:4131-46. 2007..These findings suggest spatio-temporal specificity in the accumulation of endogenous metabolites from tomato fruit... - A liquid chromatography-mass spectrometry-based metabolome database for tomatoSofia Moco
Laboratory of Biochemistry, Wageningen University, 6703 HA Wageningen, The Netherlands
Plant Physiol 141:1205-18. 2006.... - Carotenoid and fatty acid metabolism in light-stressed Dunaliella salinaPacko P Lamers
Wageningen University, Bioprocess Engineering, P O Box 8129, 6700 EV Wageningen, The Netherlands
Biotechnol Bioeng 106:638-48. 2010..Our results indicate that cellular beta-carotene accumulation in D. salina correlates with accumulation of specific fatty acid species (C16:0 and C18:1) rather than with total fatty acid content... - Untargeted large-scale plant metabolomics using liquid chromatography coupled to mass spectrometryRic C H De Vos
Plant Research International, Wageningen University and Research Centre Wageningen UR, PO Box 16, 6700 AA Wageningen, The Netherlands
Nat Protoc 2:778-91. 2007..The complete procedure from metabolite extraction to assembly of a data matrix with aligned mass signal intensities takes about 6 days for 50 samples... - A strategy for fast structural elucidation of metabolites in small volume plant extracts using automated MS-guided LC-MS-SPE-NMRJustin J J van der Hooft
Laboratory of Biochemistry, Wageningen University, Wageningen, The Netherlands BU Biosciences, Plant Research International, Wageningen, The Netherlands Netherlands Metabolomics Centre, Leiden, The Netherlands
Magn Reson Chem 49:S55-60. 2011..Our approach facilitates the more rapid unraveling of yet unknown metabolite structures and can therefore make untargeted metabolomics approaches more powerful. Copyright © 2012 John Wiley & Sons, Ltd... - Structural elucidation and quantification of phenolic conjugates present in human urine after tea intakeJustin J J van der Hooft
Laboratory of Biochemistry, Wageningen University, Dreijenlaan 3, 6703 HA, Wageningen, The Netherlands
Anal Chem 84:7263-71. 2012.... - Metabolite biodiversity in pepper (Capsicum) fruits of thirty-two diverse accessions: variation in health-related compounds and implications for breedingYuni Wahyuni
Plant Research International, 6700 AA Wageningen, The Netherlands
Phytochemistry 72:1358-70. 2011.... - A comparative study on the effect of algal and fish oil on viability and cell proliferation of Caco-2 cellsVincent A van Beelen
Division of Toxicology, Wageningen University and Research Center, Wageningen, The Netherlands
Food Chem Toxicol 45:716-24. 2007..The results of the present study support a similar mode of action of algal oil and fish oil on cancer cells in vitro, in spite of their different PUFA content... - Polyphenol identification based on systematic and robust high-resolution accurate mass spectrometry fragmentationJustin J J van der Hooft
Laboratory of Biochemistry, Wageningen University, Dreijenlaan 3, 6703 HA, Wageningen, The Netherlands
Anal Chem 83:409-16. 2011..Accurate MS(n)-based spectral tree data are therefore a powerful tool to distinguish metabolites with similar elemental formula, thereby assisting compound identification in complex biological samples such as crude plant extracts... - The genetics of plant metabolismJoost J B Keurentjes
Laboratory of Genetics, Wageningen University, Arboretumlaan 4, NL-6703 BD Wageningen, The Netherlands
Nat Genet 38:842-9. 2006..More than one-third of the signals were not detected in either parent, indicating the large potential for modification of metabolic composition through classical breeding... - Alignment and statistical difference analysis of complex peptide data sets generated by multidimensional LC-MSAntoine H P America
Plant Research International, Wageningen, The Netherlands
Proteomics 6:641-53. 2006..Our approach is a highly sensitive method to analyze proteins in complex mixtures without the need of isotope labeling... - Exploring and exploiting carotenoid accumulation in Dunaliella salina for cell-factory applicationsPacko P Lamers
Wageningen University, Department Agrotechnology and Food Sciences, 6700 EV Wageningen, The Netherlands
Trends Biotechnol 26:631-8. 2008..Ultimately, a better understanding of the regulatory mechanisms involved in beta-carotene overproduction will facilitate innovative production of specific carotenoids and other products in D. salina and in related organisms... - Gene expression programs during Brassica oleracea seed maturation, osmopriming, and germination are indicators of progression of the germination process and the stress tolerance levelYasutaka Soeda
Plant Research International B.V, 6700 AA Wageningen, The Netherlands
Plant Physiol 137:354-68. 2005..Germination-related gene expression was found to be partially reversible by physiological treatments such as slow drying of osmoprimed seeds. This correlated to the ability of seeds to withstand stress... - A proposed framework for the description of plant metabolomics experiments and their resultsHelen Jenkins
Department of Computer Science, University of Wales, Penglais, Aberystwyth, Ceredigion, Wales, UK
Nat Biotechnol 22:1601-6. 2004..armet.org/). We seek to advance discussion and community adoption of a standard for metabolomics, which would promote principled collection, storage and transmission of experiment data...