Research Topics
Species | Jules BeekwilderSummaryAffiliation: Wageningen University Country: The Netherlands Publications
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Detail Information
Publications
Antioxidants in raspberry: on-line analysis links antioxidant activity to a diversity of individual metabolitesJules Beekwilder
Plant Research International, Postbus 16, 6700 AA Wageningen, The Netherlands
J Agric Food Chem 53:3313-20. 2005..This information will assist in the future development and identification of raspberry lines with enhanced health-promoting properties...- Identification and dietary relevance of antioxidants from raspberryJules Beekwilder
Plant Research International, Wageningen, The Netherlands
Biofactors 23:197-205. 2005.... - Microbial production of natural raspberry ketoneJules Beekwilder
Plant Research International, Wageningen, The Netherlands
Biotechnol J 2:1270-9. 2007..These results therefore lay a strong foundation for a potentially renewable source of "natural" flavour compounds making use of plant genes... - Reconstitution of the costunolide biosynthetic pathway in yeast and Nicotiana benthamianaQing Liu
Laboratory of Plant Physiology, Wageningen University, Wageningen, The Netherlands
PLoS ONE 6:e23255. 2011..benthamiana leaves resulted in costunolide production of up to 60 ng.g(-1) FW. In addition, two new compounds were formed that were identified as costunolide-glutathione and costunolide-cysteine conjugates... - Production of resveratrol in recombinant microorganismsJules Beekwilder
Plant Research International, 6700 AA Wageningen, The Netherlands
Appl Environ Microbiol 72:5670-2. 2006..When p-coumaric acid was used as the precursor, resveratrol accumulations in the culture medium were observed to be comparable in E. coli (16 mg/liter) and yeast (6 mg/liter)... - Metabolism of carotenoids and apocarotenoids during ripening of raspberry fruitJules Beekwilder
Plant Research International, Wageningen, The Netherlands
Biofactors 34:57-66. 2008..Such information helps us to better understand how these compounds are produced in plants and may also enable us to develop novel strategies for improved apocarotenoid production in fruits or indeed, alternative production systems... - The impact of the absence of aliphatic glucosinolates on insect herbivory in ArabidopsisJules Beekwilder
Plant Research International, Wageningen, The Netherlands
PLoS ONE 3:e2068. 2008..6 fold higher on the double myb28myb29 mutant completely lacking aliphatic glucosinolates and 1.8 higher on the single mutants with intermediate levels of aliphatic glucosinolates compared to wild type plants... - Functional characterization of enzymes forming volatile esters from strawberry and bananaJules Beekwilder
Plant Research International, 6700 AA Wageningen, The Netherlands
Plant Physiol 135:1865-78. 2004..This confirmed that the availability of alcohol substrates is an important parameter to consider when engineering volatile ester formation in plants... - Characterization of Rhamnosidases from Lactobacillus plantarum and Lactobacillus acidophilusJules Beekwilder
Plant Research International, Wageningen, The Netherlands
Appl Environ Microbiol 75:3447-54. 2009..lactis appeared to be a limiting factor, rhamnose removal was confirmed, indicating that rhamnosidase-producing bacteria may find commercial application, depending on the technological properties of the strains and enzymes... - Isoprenoid biosynthesis in Artemisia annua: cloning and heterologous expression of a germacrene A synthase from a glandular trichome cDNA libraryCinzia M Bertea
Plant Research International, P.O. Box 16, 6700 AA Wageningen, The Netherlands
Arch Biochem Biophys 448:3-12. 2006..These results demonstrate the potential of the use of A. annua glandular trichomes as a starting material for studying isoprenoid biosynthesis in this plant species... - A chicory cytochrome P450 mono-oxygenase CYP71AV8 for the oxidation of (+)-valenceneKatarina Cankar
Laboratory of Plant Physiology, Wageningen University and Research Centre, Wageningen, The Netherlands
FEBS Lett 585:178-82. 2011..Likewise, amorpha-4,11-diene was converted to artemisinic acid. Surprisingly, the chicory P450 has a different regio-specificity on (+)-valencene compared to germacrene A and amorpha-4,11-diene... - Cloning and characterisation of a maize carotenoid cleavage dioxygenase (ZmCCD1) and its involvement in the biosynthesis of apocarotenoids with various roles in mutualistic and parasitic interactionsZhongkui Sun
Plant Research International, P O Box 16, 6700 AA, Wageningen, The Netherlands
Planta 228:789-801. 2008..ZmCCD1 is proposed to be involved in cyclohexenone and mycorradicin formation in mycorrhizal maize roots but not in strigolactone formation... - Nicotiana benthamiana as a production platform for artemisinin precursorsTeun W J M van Herpen
Laboratory of Plant Physiology, Wageningen University, Wageningen, The Netherlands
PLoS ONE 5:e14222. 2010..Here the potential of this plant is explored for rapid production of precursors of artemisinin, a sesquiterpenoid compound that is used for malaria treatment... - Co-evolution of insect proteases and plant protease inhibitorsMaarten A Jongsma
Plant Research International, Wageningen University and Research Center WageningenUR, Droevendaalsesteeg 1, P O Box 619, 6700 AP Wageningen, The Netherlands
Curr Protein Pept Sci 12:437-47. 2011.... - A broad set of different llama antibodies specific for a 16 kDa heat shock protein of Mycobacterium tuberculosisAnke K Trilling
Plant Research International, Wageningen, The Netherlands
PLoS ONE 6:e26754. 2011..Due to the small size and stable nature of llama antibody domains selected antibodies can serve as a detection reagent in multiplexed and sensitive assays for M. tuberculosis... - The effect of uniform capture molecule orientation on biosensor sensitivity: Dependence on analyte propertiesAnke K Trilling
Plant Research International, P O Box 16, 6700 AP Wageningen, The Netherlands Laboratory of Organic Chemistry of Wageningen University, P O Box 8026, 6700 EG Wageningen, The Netherlands
Biosens Bioelectron 40:219-26. 2013..The results indicate that orientation of the capture molecule hardly affects high-affinity interactions, while it leads to strong improvements in sensitivity for lower-affinity interactions... - Polyphenol identification based on systematic and robust high-resolution accurate mass spectrometry fragmentationJustin J J van der Hooft
Laboratory of Biochemistry, Wageningen University, Dreijenlaan 3, 6703 HA, Wageningen, The Netherlands
Anal Chem 83:409-16. 2011..Accurate MS(n)-based spectral tree data are therefore a powerful tool to distinguish metabolites with similar elemental formula, thereby assisting compound identification in complex biological samples such as crude plant extracts... - Identification and recombinant expression of a novel chymotrypsin from Spodoptera exiguaSalvador Herrero
Business Unit Bioscience, Plant Research International B V, Wageningen University and Research Centre, Wageningen, The Netherlands
Insect Biochem Mol Biol 35:1073-82. 2005..This suggests a possible role of this protein in the proteolytic remodelling that occurs in the gut during the larval to pupal molt... - Self-assembled functional organic monolayers on oxide-free copperMabel A Caipa Campos
Laboratory of Organic Chemistry, Wageningen University and Research Center, Dreijenplein 8, 6703 HB, Wageningen, The Netherlands
Langmuir 27:8126-33. 2011..In addition, the biotinylated copper surfaces were employed in the immobilization of biomolecules such as streptavidin... - Antioxidants, phenolic compounds, and nutritional quality of different strawberry genotypesSara Tulipani
Institute of Biochemistry, Faculty of Medicine, Department of Environmental and Crop Science SAPROV, Marche Polytechnic University, Ancona, Italy
J Agric Food Chem 56:696-704. 2008..The HPLC analyses confirmed qualitative and quantitative variability in the antioxidant profiles. These studies show that differences exist among cultivars, applicable in dietary studies in human subjects... - Changes in antioxidant and metabolite profiles during production of tomato pasteEsra Capanoglu
Faculty of Chemical and Metallurgical Engineering, Food Engineering Department, Istanbul Technical University, Maslak 34469, Istanbul, Turkey
J Agric Food Chem 56:964-73. 2008.... - Expression of plant flavor genes in Lactococcus lactisIgor Hernández
NIZO Food Research, P O Box 20, 6710 BA Ede, The Netherlands
Appl Environ Microbiol 73:1544-52. 2007..The results illustrate the potential of the application of L. lactis as a food grade expression platform for the recombinant production of proteins and bioactive compounds from plants... - Properties of purified gut trypsin from Helicoverpa zea, adapted to proteinase inhibitorsMariateresa Volpicella
Dipartimento di Biochimica e Biologia Molecolare, , Italy
Eur J Biochem 270:10-9. 2003..The same inhibitors inhibited HzTrypsin-C with apparent equilibrium dissociation constants ranging from 1 nm to 30 nm. Thus, HzTrypsin-S seems to allow the insect to overcome different defensive proteinase inhibitors in plants... - Selection by phage display of a variant mustard trypsin inhibitor toxic against aphidsLuigi R Ceci
Istituto di Biomembrane e Bioenergetica, Sezione di Trani, Via Corato 17, 70059 Trani, Italy
Plant J 33:557-66. 2003..The selected gene will allow the development of transgenic crops that are protected against sucking insect pests... - Structural basis of the resistance of an insect carboxypeptidase to plant protease inhibitorsAlex Bayes
Departament de Bioquimica i Biologia Molecular, Facultat de Ciencies, and Institut de Biotecnologia i de Biomedicina, Universitat Autonoma de Barcelona, Bellaterra, Spain
Proc Natl Acad Sci U S A 102:16602-7. 2005..This report explains a crystal structure of an insect protease and its adaptation to defensive plant protease inhibitors... - Stress-induced biosynthesis of dicaffeoylquinic acids in globe artichokeAndrea Moglia
DIVAPRA, Plant Genetics and Breeding, University of Torino, Via L da Vinci 44, 10095 Grugliasco TO Italy
J Agric Food Chem 56:8641-9. 2008..On the basis of these results a role of dicaffeoylquinic acids in UV protection in globe artichoke is hypothesized... - Identification and characterization of digestive serine proteases from inhibitor-resistant Helicoverpa zea larval midgutMariateresa Volpicella
Department of Biochemistry and Molecular Biology, University of Bari, Via Amendola 165 A, 70126 Bari, Italy
J Chromatogr B Analyt Technol Biomed Life Sci 833:26-32. 2006..The sequence features of these proteases are discussed in relation to their sensitivity to inhibitors. The results provide insight in the enzymes deployed by Helicoverpa larvae to overcome plant defence... - Response of the digestive system of Helicoverpa zea to ingestion of potato carboxypeptidase inhibitor and characterization of an uninhibited carboxypeptidase BAlex Bayes
Departament de Bioquimica i Biologia Molecular, Facultat de Ciències and Institut de Biotecnologia i de Biomedicina, Universitat Autonoma de Barcelona, E 08193 Bellaterra, Spain
Insect Biochem Mol Biol 36:654-64. 2006..The substrate specificity of recombinant CPBHz was tested using peptides. Unlike other CPB enzymes, the enzyme appeared to be highly selective for C-terminal lysine residues. Inhibition by PCI appeared to be pH-dependent... - Phage display selects for amylases with improved low pH starch-bindingRaymond M D Verhaert
Pharmaceutical Biology, University Centre for Pharmacy, A. Deusinglaan 1, 9713, AV Groningen, The Netherlands
J Biotechnol 96:103-18. 2002..5/7.5 that is improved relative to the wild type alpha-amylase. These data demonstrate that useful alpha-amylase mutants can be selected via surface display on the basis of their binding properties to starch at lowered pH values...