Ilja C W Arts

Summary

Affiliation: Wageningen University
Country: The Netherlands

Publications

  1. ncbi request reprint Intakes of 4 dietary lignans and cause-specific and all-cause mortality in the Zutphen Elderly Study
    Ivon E J Milder
    Centre for Nutrition and Health, National Institute for Public Health and the Environment, Bilthoven, Netherlands
    Am J Clin Nutr 84:400-5. 2006
  2. ncbi request reprint The type of sugar moiety is a major determinant of the small intestinal uptake and subsequent biliary excretion of dietary quercetin glycosides
    Ilja C W Arts
    RIKILT Institute of Food Safety, Wageningen University and Research Centre, Wageningen, The Netherlands
    Br J Nutr 91:841-7. 2004
  3. ncbi request reprint Polyphenols and disease risk in epidemiologic studies
    Ilja C W Arts
    RIKILT Institute of Food Safety, Wageningen University and Research Centre, Wageningen, The Netherlands
    Am J Clin Nutr 81:317S-325S. 2005
  4. ncbi request reprint SIRT1 stimulation by polyphenols is affected by their stability and metabolism
    Vincent C J de Boer
    RIKILT Institute of Food Safety, Wageningen University and Research Centre, Wageningen, The Netherlands
    Mech Ageing Dev 127:618-27. 2006
  5. doi request reprint Some phenolic compounds increase the nitric oxide level in endothelial cells in vitro
    Maaike M Appeldoorn
    RIKILT Institute of Food Safety, Wageningen, The Netherlands
    J Agric Food Chem 57:7693-9. 2009
  6. ncbi request reprint Plant foods versus compounds in carcinogenesis; observational versus experimental human studies
    Ellen Kampman
    Division of Human Nutrition and Epidemiology, Wageningen University and Research Centre 6700, EV Wageningen, The Netherlands
    Int J Vitam Nutr Res 73:70-8. 2003
  7. ncbi request reprint Tissue distribution of quercetin in rats and pigs
    Vincent C J de Boer
    RIKILT Institute of Food Safety, Wageningen University and Research Centre, Wageningen, The Netherlands
    J Nutr 135:1718-25. 2005
  8. ncbi request reprint Lignan contents of Dutch plant foods: a database including lariciresinol, pinoresinol, secoisolariciresinol and matairesinol
    Ivon E J Milder
    RIKILT Institute of Food Safety, Wageningen University and Research Centre, Wageningen, The Netherlands
    Br J Nutr 93:393-402. 2005
  9. ncbi request reprint A validated method for the quantification of enterodiol and enterolactone in plasma using isotope dilution liquid chromatography with tandem mass spectrometry
    Anneleen Kuijsten
    RIKILT, Institute of Food Safety, Wageningen UR, PO Box 230, 6700 AE, Wageningen, The Netherlands
    J Chromatogr B Analyt Technol Biomed Life Sci 822:178-84. 2005
  10. ncbi request reprint Dietary catechins and cancer incidence among postmenopausal women: the Iowa Women's Health Study (United States)
    Ilja C W Arts
    National Institute of Public Health and the Environment RIVM, Department of Chronic Diseases Epidemiology, Bilthoven, The Netherlands
    Cancer Causes Control 13:373-82. 2002

Collaborators

Detail Information

Publications19

  1. ncbi request reprint Intakes of 4 dietary lignans and cause-specific and all-cause mortality in the Zutphen Elderly Study
    Ivon E J Milder
    Centre for Nutrition and Health, National Institute for Public Health and the Environment, Bilthoven, Netherlands
    Am J Clin Nutr 84:400-5. 2006
    ..Plant lignans are converted to enterolignans that have antioxidant and weak estrogen-like activities, and therefore they may lower cardiovascular disease and cancer risks...
  2. ncbi request reprint The type of sugar moiety is a major determinant of the small intestinal uptake and subsequent biliary excretion of dietary quercetin glycosides
    Ilja C W Arts
    RIKILT Institute of Food Safety, Wageningen University and Research Centre, Wageningen, The Netherlands
    Br J Nutr 91:841-7. 2004
    ..The poor bioavailability of important dietary quercetin glycosides has implications for their in vivo bioactivities...
  3. ncbi request reprint Polyphenols and disease risk in epidemiologic studies
    Ilja C W Arts
    RIKILT Institute of Food Safety, Wageningen University and Research Centre, Wageningen, The Netherlands
    Am J Clin Nutr 81:317S-325S. 2005
    ..Careful design of prospective studies is important to offset some of the major drawbacks of epidemiologic studies, including residual confounding (by smoking and other dietary factors) and exposure assessment...
  4. ncbi request reprint SIRT1 stimulation by polyphenols is affected by their stability and metabolism
    Vincent C J de Boer
    RIKILT Institute of Food Safety, Wageningen University and Research Centre, Wageningen, The Netherlands
    Mech Ageing Dev 127:618-27. 2006
    ..This study shows that the stimulation of SIRT1 is strongly affected by polyphenol stability and metabolism, therefore extrapolation of in vitro SIRT1 stimulation results to physiological effects should be done with caution...
  5. doi request reprint Some phenolic compounds increase the nitric oxide level in endothelial cells in vitro
    Maaike M Appeldoorn
    RIKILT Institute of Food Safety, Wageningen, The Netherlands
    J Agric Food Chem 57:7693-9. 2009
    ..Use of this assay showed that only a limited number of phenolic compounds might enhance NO level with an increased amount of eNOS enzyme as a possible contributing mechanism...
  6. ncbi request reprint Plant foods versus compounds in carcinogenesis; observational versus experimental human studies
    Ellen Kampman
    Division of Human Nutrition and Epidemiology, Wageningen University and Research Centre 6700, EV Wageningen, The Netherlands
    Int J Vitam Nutr Res 73:70-8. 2003
    ..An integrated approach combining designs, and implementing new techniques to identify biomarkers, may clarify the role of plant foods in carcinogenesis...
  7. ncbi request reprint Tissue distribution of quercetin in rats and pigs
    Vincent C J de Boer
    RIKILT Institute of Food Safety, Wageningen University and Research Centre, Wageningen, The Netherlands
    J Nutr 135:1718-25. 2005
    ..These studies have for the first time identified target tissues of quercetin, which may help to understand its mechanisms of action in vivo...
  8. ncbi request reprint Lignan contents of Dutch plant foods: a database including lariciresinol, pinoresinol, secoisolariciresinol and matairesinol
    Ivon E J Milder
    RIKILT Institute of Food Safety, Wageningen University and Research Centre, Wageningen, The Netherlands
    Br J Nutr 93:393-402. 2005
    ..Thus, available databases largely underestimate the amount of enterolignan precursors in foods...
  9. ncbi request reprint A validated method for the quantification of enterodiol and enterolactone in plasma using isotope dilution liquid chromatography with tandem mass spectrometry
    Anneleen Kuijsten
    RIKILT, Institute of Food Safety, Wageningen UR, PO Box 230, 6700 AE, Wageningen, The Netherlands
    J Chromatogr B Analyt Technol Biomed Life Sci 822:178-84. 2005
    ..The within-run R.S.D. ranges from 3 to 6% and the between-run R.S.D. ranges from 10 to 14% for both enterolignans. This method allows simple, rapid, and sensitive quantification, and is suitable for measuring large numbers of samples...
  10. ncbi request reprint Dietary catechins and cancer incidence among postmenopausal women: the Iowa Women's Health Study (United States)
    Ilja C W Arts
    National Institute of Public Health and the Environment RIVM, Department of Chronic Diseases Epidemiology, Bilthoven, The Netherlands
    Cancer Causes Control 13:373-82. 2002
    ..We investigated whether a high intake of catechins are associated with cancer incidence among postmenopausal women...
  11. ncbi request reprint Intake of the plant lignans secoisolariciresinol, matairesinol, lariciresinol, and pinoresinol in Dutch men and women
    Ivon E J Milder
    Centre for Nutrition and Health, National Institute for Public Health and the Environment, 3720 BA Bilthoven, The Netherlands
    J Nutr 135:1202-7. 2005
    ..In brief, this study shows that the amount of enterolignan precursors in the diet has previously been largely underestimated...
  12. ncbi request reprint A review of the epidemiological evidence on tea, flavonoids, and lung cancer
    Ilja C W Arts
    Department of Epidemiology, Nutrition, Toxicology Research Institute Maastricht, Maastricht University, 6200 MD, Maastricht, The Netherlands
    J Nutr 138:1561S-1566S. 2008
    ..More well-designed cohort studies, in particular for catechins, are needed to strengthen the evidence on effects of long-term exposure to physiological doses of dietary flavonoids...
  13. ncbi request reprint Relation between plasma enterodiol and enterolactone and dietary intake of lignans in a Dutch endoscopy-based population
    Ivon E J Milder
    Centre for Nutrition and Health, National Institute of Public Health and the Environment, 3720 BA Bilthoven, The Netherlands
    J Nutr 137:1266-71. 2007
    ..However, even when we included these nondietary factors in the regression models, the explained variance in plasma END and ENL remained low (2 and 13%, respectively)...
  14. ncbi request reprint Plasma enterolignans are associated with lower colorectal adenoma risk
    Anneleen Kuijsten
    Division of Human Nutrition, Wageningen University, The Netherlands
    Cancer Epidemiol Biomarkers Prev 15:1132-6. 2006
    ..09). We observed a substantial reduction in colorectal adenoma risk among subjects with high plasma concentrations of enterolignans, in particular, enterodiol. These findings could be important in the prevention of colorectal adenomas...
  15. ncbi request reprint Quercetin-3-glucoside is transported by the glucose carrier SGLT1 across the brush border membrane of rat small intestine
    Ilja C W Arts
    J Nutr 132:2823; author reply 2824. 2002
  16. ncbi request reprint Phytoestrogens and risk of lung cancer
    Peter C H Hollman
    JAMA 295:755; author reply 755-6. 2006
  17. ncbi request reprint The relative bioavailability of enterolignans in humans is enhanced by milling and crushing of flaxseed
    Anneleen Kuijsten
    RIKILT Institute of Food Safety, Wageningen UR, The Netherlands
    J Nutr 135:2812-6. 2005
    ..01), whereas that of crushed compared with ground flaxseed was 43% (P < or = 0.01). Crushing and milling of flaxseed substantially improve the bioavailability of the enterolignans...
  18. ncbi request reprint Intestinal uptake of quercetin-3-glucoside in rats involves hydrolysis by lactase phlorizin hydrolase
    Aloys L A Sesink
    Department of Pharmacology and Toxicology, Nijmegen Center for Molecular Life Sciences, The Netherlands
    J Nutr 133:773-6. 2003
    ..12), 55% (P < 0.01) and 75% (P < 0.01) lower than in controls (1.23 +/- 0.22 micro mol/L). These data suggest that LPH is a major determinant of intestinal absorption of quercetin-3-glucoside in rats...
  19. ncbi request reprint Breast cancer resistance protein (Bcrp1/Abcg2) limits net intestinal uptake of quercetin in rats by facilitating apical efflux of glucuronides
    Aloys L A Sesink
    Department of Pharmacology and Toxicology 233, Nijmegen Centre for Molecular Life Sciences, Radboud University Nijmegen Medical Centre, P O Box 9101, 6500 HB Nijmegen, The Netherlands
    Mol Pharmacol 67:1999-2006. 2005
    ..In conclusion, Bcrp1 limits net intestinal absorption of quercetin by pumping quercetin glucuronides back into the lumen...