Research Topics
| Eric Ch WoltersSummaryAffiliation: VU University Medical Center Country: The Netherlands Publications
| Collaborators
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Detail Information
Publications
Management of psychosis in Parkinson's diseaseE C Wolters
Vrije Universiteit Medical Center, Amsterdam, The Netherlands
Curr Opin Neurol 14:499-504. 2001..Cholinomimetic therapy may prove to be helpful in the prevention and treatment of psychotic manifestations in Parkinson's disease patients, given the effects observed in patients suffering from dementia with Lewy bodies...
Parkinson's disease-related disorders in the impulsive-compulsive spectrumEric Ch Wolters
Dept of Neurology, VU University Medical Center, Amsterdam, The Netherlands
J Neurol 255:48-56. 2008..The extrinsic impulse control disorders might be best treated by reducing or replacing dopamine receptor agonists...
Abnormal susceptibility to distracters hinders perception in early stage Parkinson's disease: a controlled studyJan Berend Deijen
Department of Clinical Neuropsychology, Vrije Universiteit, Van der Boechorststraat 1, 1081 BT, Amsterdam, The Netherlands
BMC Neurol 6:43. 2006..Impairment of substantia nigra function is thought to lead to this reduced ability to suppress reflexive saccades...- Deep brain stimulation and continuous dopaminergic stimulation in advanced Parkinson's diseaseErik Ch Wolters
Department of Neurology, VU University Medical Center, Amsterdam, The Netherlands
Parkinsonism Relat Disord 13:S18-23. 2007..Of these, duodenal levodopa infusion appears to be the most promising option in terms of both efficacy and safety... - Variability in the clinical expression of Parkinson's diseaseErik Ch Wolters
Department of Neurology, VU University Medical Center, P O Box 7057, 1007 MB Amsterdam, The Netherlands
J Neurol Sci 266:197-203. 2008..Better insight in the clinicopathological correlations of this disease may help to further develop early diagnosis and adequate therapeutic strategies... - Olfactory testing combined with dopamine transporter imaging as a method to detect prodromal Parkinson's diseaseMirthe M Ponsen
Department of Neurology, VU University Medical Center, De Boelelaan 1117, 1081 HV Amsterdam, The Netherlands
J Neurol Neurosurg Psychiatry 81:396-9. 2010..The usefulness of this two-step approach needs to be confirmed in larger populations... - Frontal-striatal abnormalities underlying behaviours in the compulsive-impulsive spectrumOdile A van den Heuvel
Department of Psychiatry, VU University Medical Center, Amsterdam, The Netherlands
J Neurol Sci 289:55-9. 2010.... - Hyposmia and executive dysfunction as predictors of future Parkinson's disease: a prospective studyMirthe M Ponsen
Department of Neurology, VU University Medical Center, Amsterdam, The Netherlands
Mov Disord 24:1060-5. 2009..Interestingly, impaired odor discrimination was the best predictor for future PD... - Extended testing across, not within, tasks raises diagnostic accuracy of smell testing in Parkinson's diseaseSanne Boesveldt
Department of Neurology, VU University Medical Center, Amsterdam, The Netherlands
Mov Disord 24:85-90. 2009..A combination of an odor detection threshold task and a 16-item odor identification test had the highest sensitivity and specificity in distinguishing between PD patients and controls... - Dopaminergic modulation of cortico-cortical functional connectivity in Parkinson's disease: an MEG studyDiederick Stoffers
Institute for Clinical and Experimental Neurosciences, Department of Neurology, VU University Medical Center, Amsterdam, The Netherlands
Exp Neurol 213:191-5. 2008..However, a strong motor response appears to be associated with decreases in local beta-band coupling, which may constitute a risk factor for the development of motor response fluctuations or dyskinesias... - Impairment of complex upper limb motor function in de novo Parkinson's diseaseMirthe M Ponsen
Department of Neurology, ICEN, VU University Medical Center Amsterdam, De Boelelaan 1117, 1081 HVAmsterdam, The Netherlands
Parkinsonism Relat Disord 14:199-204. 2008..The results of this study extend previous observations of impaired complex upper limb movements to newly diagnosed, untreated PD patients... - Bimanual coordination dysfunction in early, untreated Parkinson's diseaseMirthe M Ponsen
ICEN, Department of Neurology, VU University Medical Center Amsterdam, De Boelelaan 1117, 1081 HV Amsterdam, The Netherlands
Parkinsonism Relat Disord 12:246-52. 2006..This study demonstrates that bimanual coordination dysfunction is a very early sign of PD. Bimanual coordination tasks, in particular those involving high frequency anti-phase movements, might prove useful in the early diagnosis of PD... - Idiopathic hyposmia as a preclinical sign of Parkinson's diseaseMirthe M Ponsen
Research Institute Neurosciences Vrije Universiteit, Department of Neurology, VU University Medical Center Amsterdam, The Netherlands
Ann Neurol 56:173-81. 2004..These results indicate that idiopathic olfactory dysfunction is associated with an increased risk of developing PD of at least 10%... - Non-motor extranigral signs and symptoms in Parkinson's diseaseErik Ch Wolters
Neuroscience Campus Amsterdam, Dept of Neurology, VU University Medical Center, Amsterdam, The Netherlands
Parkinsonism Relat Disord 15:S6-12. 2009..Of course, also the recognition of the signs and symptoms of the prodromal (premotor) phase, suggestive for the presence of the PD, will be discussed. Iatrogenic non-motor symptoms, though, will not be further discussed... - Enhanced sensitivity of dopaminergic neurons to rotenone-induced toxicity with agingAmie L Phinney
Department of Medical Pharmacology, Institute for Clinical and Experimental Neurosciences, VU University Medical Center, Van der Boechorststraat 7, 1081 BT Amsterdam, The Netherlands
Parkinsonism Relat Disord 12:228-38. 2006..These data suggest that age enhances the sensitivity of dopaminergic neurons to rotenone and should be considered when assessing models of Parkinson's disease...