Willem van Mechelen


Affiliation: VU University Medical Center
Country: The Netherlands


  1. Pillay J, van der Ploeg H, Kolbe Alexander T, Proper K, van Stralen M, Tomaz S, et al. The association between daily steps and health, and the mediating role of body composition: a pedometer-based, cross-sectional study in an employed South African population. BMC Public Health. 2015;15:174 pubmed publisher
    ..The integration of volume, intensity and duration of ambulatory physical activity in pedometer-based messages is of emerging relevance. ..
  2. Lammerts L, Schaafsma F, Eikelenboom M, Vermeulen S, van Mechelen W, Anema J, et al. Longitudinal Associations Between Biopsychosocial Factors and Sustainable Return to Work of Sick-Listed Workers with a Depressive or Anxiety Disorder. J Occup Rehabil. 2016;26:70-9 pubmed publisher
    ..Policy and research should focus on facilitators and barriers for return to work of workers with these characteristics. ..
  3. Hespanhol Junior L, Pillay J, van Mechelen W, Verhagen E. Meta-Analyses of the Effects of Habitual Running on Indices of Health in Physically Inactive Adults. Sports Med. 2015;45:1455-68 pubmed publisher
    ..The longer the length of training, the larger the achieved health benefits. Clinicians and health authorities can use this information to advise individuals to run, and to support policies towards investing in running programs. ..
  4. Broekhuizen K, van Wier M, Koppes L, Brug J, van Mechelen W, Bosmans J, et al. An economic evaluation alongside a randomized controlled trial evaluating an individually tailored lifestyle intervention compared with usual care in people with familial hypercholesterolemia. BMC Res Notes. 2015;8:317 pubmed publisher
    ..The intervention is not cost-effective. NTR1899, date 07-07-2009. ..
  5. Merkus S, Holte K, Huysmans M, van Mechelen W, van der Beek A. Nonstandard working schedules and health: the systematic search for a comprehensive model. BMC Public Health. 2015;15:1084 pubmed publisher
    ..The model gives researchers a useful overview over the various risk factors and pathways associated with health that should be considered when studying any form of nonstandard working schedule. ..
  6. Hupperets M, Verhagen E, van Mechelen W. The 2BFit study: is an unsupervised proprioceptive balance board training programme, given in addition to usual care, effective in preventing ankle sprain recurrences? Design of a randomized controlled trial. BMC Musculoskelet Disord. 2008;9:71 pubmed publisher
    ..Results of this study could possibly lead to changes in practical guidelines on the treatment of ankle sprains. Results will become available in 2009. ISTRCN34177180. ..
  7. Kampshoff C, Chinapaw M, Brug J, Twisk J, Schep G, Nijziel M, et al. Randomized controlled trial of the effects of high intensity and low-to-moderate intensity exercise on physical fitness and fatigue in cancer survivors: results of the Resistance and Endurance exercise After ChemoTherapy (REACT) study. BMC Med. 2015;13:275 pubmed publisher
    ..HI and LMI exercise were equally effective in reducing general and physical fatigue. This study was registered at the Netherlands Trial Register [ NTR2153 ] on the 5th of January 2010. ..
  8. van den Berg M, Maas J, Muller R, Braun A, Kaandorp W, van Lien R, et al. Autonomic Nervous System Responses to Viewing Green and Built Settings: Differentiating Between Sympathetic and Parasympathetic Activity. Int J Environ Res Public Health. 2015;12:15860-74 pubmed publisher
    ..Overall, our findings are consistent with a predominant role of the parasympathetic nervous system in restorative effects of viewing green space. ..
  9. Buffart L, Kalter J, Sweegers M, Courneya K, Newton R, Aaronson N, et al. Effects and moderators of exercise on quality of life and physical function in patients with cancer: An individual patient data meta-analysis of 34 RCTs. Cancer Treat Rev. 2017;52:91-104 pubmed publisher
    ..Although effect sizes are small, there is consistent empirical evidence to support implementation of exercise as part of cancer care. ..

More Information


  1. Vonk Noordegraaf A, Huirne J, Brolmann H, Emanuel M, van Kesteren P, Kleiverda G, et al. Effectiveness of a multidisciplinary care program on recovery and return to work of patients after gynaecological surgery; design of a randomized controlled trial. BMC Health Serv Res. 2012;12:29 pubmed publisher
    ..Netherlands Trial Register (NTR): NTR2087. ..
  2. van Oostrom S, Anema J, Terluin B, Venema A, de Vet H, van Mechelen W. Development of a workplace intervention for sick-listed employees with stress-related mental disorders: Intervention Mapping as a useful tool. BMC Health Serv Res. 2007;7:127 pubmed
    ..Intervention Mapping was found to be a promising method to develop interventions tailored to a specific target group in the field of occupational health. ..
  3. Chin A Paw M, van Poppel M, van Mechelen W. Effects of resistance and functional-skills training on habitual activity and constipation among older adults living in long-term care facilities: a randomized controlled trial. BMC Geriatr. 2006;6:9 pubmed
    ..Six months of moderate intensity exercise training neither enhances habitual physical activity nor affects complaints of constipation among older people living in long-term care facilities. ..
  4. Resaland G, Aadland E, Moe V, Aadland K, Skrede T, Stavnsbo M, et al. Effects of physical activity on schoolchildren's academic performance: The Active Smarter Kids (ASK) cluster-randomized controlled trial. Prev Med. 2016;91:322-328 pubmed publisher
    ..Still, combining physical activity and learning seems a viable model to stimulate learning in those academically weakest schoolchildren. ..