Thielen N, van der Holt B, Cornelissen J, Verhoef G, Gussinklo T, Biemond B, et al. Imatinib discontinuation in chronic phase myeloid leukaemia patients in sustained complete molecular response: a randomised trial of the Dutch-Belgian Cooperative Trial for Haemato-Oncology (HOVON). Eur J Cancer. 2013;49:3242-6 pubmed publisher
..All evaluable patients remained sensitive to imatinib after reinitiation and regained a molecular response. Our data suggest that discontinuation of imatinib is safe in patients with durable MR(4.5). ..