Research Topics
| Eleonora L SwartSummaryAffiliation: VU University Medical Center Country: The Netherlands Publications
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Detail Information
Publications
Growing up with midazolam in the neonatal and pediatric intensive careEleonora L Swart
Dept Clinical Pharmacology and Pharmacy, VU University Medical Center, P O Box 7057, 1007 MB Amsterdam, The Netherlands
Curr Drug Metab 13:760-6. 2012..Both are subject to considerable developmental changes. It remains remarkable that high-quality evidence to support the use of midazolam for continuous sedation in the neonatal and pediatric intensive care setting is lacking...
Comparative population pharmacokinetics of lorazepam and midazolam during long-term continuous infusion in critically ill patientsEleonora L Swart
Department of Pharmacy, Vrije Universiteit Medical Center, PO Box 7057, 1007 MB Amsterdam, The Netherlands
Br J Clin Pharmacol 57:135-45. 2004..The objective of this study was to compare the population pharmacokinetics of lorazepam and midazolam after long-term continuous infusion in mechanically ventilated critically ill patients...
Population pharmacokinetics of lorazepam and midazolam and their metabolites in intensive care patients on continuous venovenous hemofiltrationEleonora L Swart
Department of Pharmacy, Vrije Universiteit Medical Center, Amsterdam, The Netherlands
Am J Kidney Dis 45:360-71. 2005..The objective is to study the population pharmacokinetics of lorazepam and midazolam in critically ill patients with acute renal failure who are treated with continuous venovenous hemofiltration (CVVH)...
Population pharmacodynamic modelling of lorazepam- and midazolam-induced sedation upon long-term continuous infusion in critically ill patientsEleonora L Swart
Department of Pharmacy, Vrije Universiteit Medical Center, Amsterdam, The Netherlands
Eur J Clin Pharmacol 62:185-94. 2006..The objective of the present investigation was to develop a population pharmacodynamic model for midazolam- and lorazepam-induced sedation upon long-term continuous infusion in critically ill patients...
The use of capecitabine in daily practice: a study on adherence and patients' experiencesLonneke Timmers
Department of Clinical Pharmacology and Pharmacy, VU University Medical Center, Amsterdam, The Netherlands
Patient Prefer Adherence 6:741-8. 2012....
Age is of influence on midazolam requirements in a paediatric intensive care unitDana Anne H de Gast Bakker
Department of Paediatric Intensive Care, VU Medical Center, Amsterdam, The Netherlands
Acta Paediatr 96:414-7. 2007..To test that age is of influence on midazolam requirements during prolonged mechanical ventilation in critically ill children...
Quantitative analysis of sildenafil and desmethylsildenafil in human serum by liquid chromatography-mass spectrometry with minimal sample pretreatmentRené M Vos
Department of Clinical Pharmacology and Pharmacy, VU University Medical Center, Amsterdam, The Netherlands
J Chromatogr B Analyt Technol Biomed Life Sci 876:283-7. 2008..Intra- and inter-day accuracy of sildenafil and desmethylsildenafil ranged from 92 to 103%. This method has been used in a clinical pharmacokinetic study of sildenafil in intensive care patients...
The use of erlotinib in daily practice: a study on adherence and patients' experiencesLonneke Timmers
Department of Clinical Pharmacology and Pharmacy, VU University Medical Center, De Boelelaan 1117, 1081 HV Amsterdam, The Netherlands
BMC Cancer 11:284. 2011....
Correlation between midazolam and lignocaine pharmacokinetics and MEGX formation in healthy volunteersEleonora L Swart
Department of Pharmacy and Medical Intensive Care Unit, University Hospital Vrije Universiteit, PO Box 7057, 1007 MB Amsterdam, The Netherlands
Br J Clin Pharmacol 53:133-9. 2002....
Population pharmacokinetics of ciclosporin in haematopoietic allogeneic stem cell transplantation with emphasis on limited sampling strategyAbraham J Wilhelm
Department of Clinical Pharmacology and Pharmacy, VU University Medical Centre, Amsterdam, The Netherlands
Br J Clin Pharmacol 73:553-63. 2012..With the Bayesian estimators from this model, the area under the concentration-time curve in HSCT patients taking fluconazole can be estimated with only three blood samples (0, 2, 3 h) with a bias of 1% and precision of 4%...
Potential drug interactions and duplicate prescriptions among ambulatory cancer patients: a prevalence study using an advanced screening methodRoelof W F van Leeuwen
Department of Clinical Pharmacology and Pharmacy, VU University Medical Center, Amsterdam, The Netherlands
BMC Cancer 10:679. 2010..For the first time the prevalence of drug interactions with OTC-drugs in cancer patients will be studied. Possible risk factors for the occurrence of these drug-related problems will also be studied...
Sildenafil attenuates pulmonary arterial pressure but does not improve oxygenation during ARDSAlexander D Cornet
Department of Intensive Care, VU University Medical Center, De Boelelaan 1117, Amsterdam, The Netherlands
Intensive Care Med 36:758-64. 2010..Administration of sildenafil in ambulatory patients with pulmonary hypertension improves oxygenation and ameliorates pulmonary hypertension. Our aim was to determine whether sildenafil is beneficial for patients with ARDS...
