Rik Ossenkoppele

Summary

Affiliation: VU University Medical Center
Country: The Netherlands

Publications

  1. ncbi request reprint [Amyloid-plaque imaging of the brain using PET]
    Rik Ossenkoppele
    VU Medisch Centrum, Afd Nucleaire Geneeskunde and PET Research, Amsterdam, The Netherlands
    Ned Tijdschr Geneeskd 155:A2981. 2011
  2. doi request reprint Impact of molecular imaging on the diagnostic process in a memory clinic
    Rik Ossenkoppele
    Department of Neurology and Alzheimer Center, VU University Medical Center, Amsterdam, The Netherlands
    Alzheimers Dement 9:414-21. 2013
  3. doi request reprint Differential effect of APOE genotype on amyloid load and glucose metabolism in AD dementia
    Rik Ossenkoppele
    Department of Neurology and Alzheimer Center, VU University Medical Center, Amsterdam, The Netherlands
    Neurology 80:359-65. 2013
  4. doi request reprint Amyloid burden and metabolic function in early-onset Alzheimer's disease: parietal lobe involvement
    Rik Ossenkoppele
    Department of Neurology and Alzheimer Center, VU University Medical Center, PO Box 7057, 1007 MB Amsterdam, The Netherlands
    Brain 135:2115-25. 2012
  5. doi request reprint Longitudinal imaging of Alzheimer pathology using [11C]PIB, [18F]FDDNP and [18F]FDG PET
    Rik Ossenkoppele
    Department of Neurology and Alzheimer Center, VU University Medical Center, PO Box 7057, 1007MB, Amsterdam, Netherlands
    Eur J Nucl Med Mol Imaging 39:990-1000. 2012
  6. pmc Amyloid imaging in prodromal Alzheimer's disease
    Rik Ossenkoppele
    Department of Neurology and Alzheimer Center, VU University Medical Center, Amsterdam, 1007 MB Amsterdam, The Netherlands
    Alzheimers Res Ther 3:26. 2011
  7. doi request reprint Longitudinal amyloid imaging using 11C-PiB: methodologic considerations
    Bart N M van Berckel
    Department of Nuclear Medicine and PET Research, VU University Medical Center, Amsterdam, The Netherlands
    J Nucl Med 54:1570-6. 2013
  8. doi request reprint Amyloid and its association with default network integrity in Alzheimer's disease
    Sofie M Adriaanse
    Department of Nuclear Medicine and PET Research, Alzheimer Center Amsterdam, VU University Medical Center, Amsterdam, The Netherlands
    Hum Brain Mapp 35:779-91. 2014

Detail Information

Publications8

  1. ncbi request reprint [Amyloid-plaque imaging of the brain using PET]
    Rik Ossenkoppele
    VU Medisch Centrum, Afd Nucleaire Geneeskunde and PET Research, Amsterdam, The Netherlands
    Ned Tijdschr Geneeskd 155:A2981. 2011
    ..In the future, amyloid imaging could also be useful for selecting patients for clinical trials and in evaluating the effects of disease modifying agents tailored at lowering Aβ burden...
  2. doi request reprint Impact of molecular imaging on the diagnostic process in a memory clinic
    Rik Ossenkoppele
    Department of Neurology and Alzheimer Center, VU University Medical Center, Amsterdam, The Netherlands
    Alzheimers Dement 9:414-21. 2013
    ..We evaluated the impact of these tracers on the diagnostic process in a memory clinic population...
  3. doi request reprint Differential effect of APOE genotype on amyloid load and glucose metabolism in AD dementia
    Rik Ossenkoppele
    Department of Neurology and Alzheimer Center, VU University Medical Center, Amsterdam, The Netherlands
    Neurology 80:359-65. 2013
    ..To examine the relationships between apolipoprotein E (APOE) ε4 dose and in vivo distributions of both fibrillary amyloid burden and glucose metabolism in the same Alzheimer disease dementia patients, selected for abnormal amyloid imaging...
  4. doi request reprint Amyloid burden and metabolic function in early-onset Alzheimer's disease: parietal lobe involvement
    Rik Ossenkoppele
    Department of Neurology and Alzheimer Center, VU University Medical Center, PO Box 7057, 1007 MB Amsterdam, The Netherlands
    Brain 135:2115-25. 2012
    ..As such, increased amyloid burden, together with metabolic dysfunction, in the parietal lobe of younger patients with Alzheimer's disease may contribute to the distinct cognitive profile in these patients...
  5. doi request reprint Longitudinal imaging of Alzheimer pathology using [11C]PIB, [18F]FDDNP and [18F]FDG PET
    Rik Ossenkoppele
    Department of Neurology and Alzheimer Center, VU University Medical Center, PO Box 7057, 1007MB, Amsterdam, Netherlands
    Eur J Nucl Med Mol Imaging 39:990-1000. 2012
    ..18)F]FDG is a glucose analogue and its uptake reflects metabolic activity. The purpose of this study was to examine longitudinal changes in these tracers in patients with AD or mild cognitive impairment (MCI) and in healthy controls...
  6. pmc Amyloid imaging in prodromal Alzheimer's disease
    Rik Ossenkoppele
    Department of Neurology and Alzheimer Center, VU University Medical Center, Amsterdam, 1007 MB Amsterdam, The Netherlands
    Alzheimers Res Ther 3:26. 2011
    ..These findings may have important implications for the design of future clinical trials aimed at preventing progression to Alzheimer's disease by lowering the brain amyloid-beta burden in patients with mild cognitive impairment...
  7. doi request reprint Longitudinal amyloid imaging using 11C-PiB: methodologic considerations
    Bart N M van Berckel
    Department of Nuclear Medicine and PET Research, VU University Medical Center, Amsterdam, The Netherlands
    J Nucl Med 54:1570-6. 2013
    ..Several methods are in use for analyzing (11)C-Pittsburgh compound-B ((11)C-PiB) data. The objective of this study was to identify the method of choice for measuring longitudinal changes in specific (11)C-PiB binding...
  8. doi request reprint Amyloid and its association with default network integrity in Alzheimer's disease
    Sofie M Adriaanse
    Department of Nuclear Medicine and PET Research, Alzheimer Center Amsterdam, VU University Medical Center, Amsterdam, The Netherlands
    Hum Brain Mapp 35:779-91. 2014
    ..Longitudinal studies are needed to examine if amyloid depositions precede aberrant functional connectivity in the DMN. Hum Brain Mapp 35:779-791, 2014. © 2012 Wiley Periodicals, Inc. ..