- miR-101 is down-regulated in glioblastoma resulting in EZH2-induced proliferation, migration, and angiogenesisMichiel Smits
Neuro oncology Research Group, Departments of Neurosurgery and Pediatric Oncology Hematology, Cancer Center Amsterdam, VU University Medical Center, Amsterdam, The Netherlands
Oncotarget 1:710-20. 2010..GBM is characterized by fast cell proliferation, infiltrative migration, and by the induction of angiogenesis. MicroRNAs and polycomb group (PcG) proteins have emerged as important regulators of gene expression...
- Prostate cancer-derived urine exosomes: a novel approach to biomarkers for prostate cancerJ Nilsson
Department of Radiation Sciences, Oncology, Umea University, Umea, Sweden
Br J Cancer 100:1603-7. 2009..As a proof-of-concept, we show the presence of two known prostate cancer biomarkers, PCA-3 and TMPRSS2:ERG the in exosomes isolated from urine of patients, showing the potential for diagnosis and monitoring cancer patients status...