Atoosa Familian

Summary

Affiliation: VU University Medical Center
Country: The Netherlands

Publications

  1. ncbi request reprint Inhibitory effect of minocycline on amyloid beta fibril formation and human microglial activation
    Atoosa Familian
    Department of Psychiatry, Institute for Clinical and Experimental Neurosciences VU ICEN VU, VU University Medical Center, Amsterdam, The Netherlands
    Glia 53:233-40. 2006
  2. ncbi request reprint Minocycline does not affect amyloid beta phagocytosis by human microglial cells
    Atoosa Familian
    Department of Psychiatry, VU University Medical Center, Amsterdam, The Netherlands
    Neurosci Lett 416:87-91. 2007
  3. doi request reprint Neuroinflammation in plaque and vascular beta-amyloid disorders: clinical and therapeutic implications
    Piet Eikelenboom
    Department of Neurology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    Neurodegener Dis 5:190-3. 2008

Detail Information

Publications3

  1. ncbi request reprint Inhibitory effect of minocycline on amyloid beta fibril formation and human microglial activation
    Atoosa Familian
    Department of Psychiatry, Institute for Clinical and Experimental Neurosciences VU ICEN VU, VU University Medical Center, Amsterdam, The Netherlands
    Glia 53:233-40. 2006
    ..Our data suggest that minocycline and tetracycline at tolerable doses can inhibit human microglial activation. This activity in part is exerted by inhibition of (SAP and C1q enhanced) Abeta fibril formation...
  2. ncbi request reprint Minocycline does not affect amyloid beta phagocytosis by human microglial cells
    Atoosa Familian
    Department of Psychiatry, VU University Medical Center, Amsterdam, The Netherlands
    Neurosci Lett 416:87-91. 2007
    ..Here, we demonstrate that minocycline down-regulates the production of pro-inflammatory cytokines by human microglia without affecting their beneficial activity, phagocytosis of amyloid beta fibrils...
  3. doi request reprint Neuroinflammation in plaque and vascular beta-amyloid disorders: clinical and therapeutic implications
    Piet Eikelenboom
    Department of Neurology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    Neurodegener Dis 5:190-3. 2008
    ..The cerebral beta-amyloid (Abeta) disorders show a great variability in the distribution of parenchymal and vascular amyloid deposits...