Babs O Fabriek

Summary

Affiliation: VU University Medical Center
Country: The Netherlands

Publications

  1. ncbi In vivo detection of myelin proteins in cervical lymph nodes of MS patients using ultrasound-guided fine-needle aspiration cytology
    Babs O Fabriek
    Department of Molecular Cell Biology and Immunology, VU Medical Center, P O Box 7057, 1007 MB Amsterdam, The Netherlands
    J Neuroimmunol 161:190-4. 2005
  2. ncbi CD163-positive perivascular macrophages in the human CNS express molecules for antigen recognition and presentation
    Babs O Fabriek
    Department of Molecular Cell Biology and Immunology, VU Medical Center, Amsterdam, The Netherlands
    Glia 51:297-305. 2005
  3. ncbi The macrophage scavenger receptor CD163
    Babs O Fabriek
    Department of Molecular Cell Biology and Immunology, VU Medical Center, P O Box 7057, 1007MB Amsterdam, The Netherlands
    Immunobiology 210:153-60. 2005
  4. ncbi The macrophage scavenger receptor CD163 functions as an innate immune sensor for bacteria
    Babs O Fabriek
    Department of Molecular Cell Biology and Immunology, VU Medical Center, Amsterdam
    Blood 113:887-92. 2009
  5. ncbi Proteolytic shedding of the macrophage scavenger receptor CD163 in multiple sclerosis
    Babs O Fabriek
    Department of Molecular Cell Biology and Immunology, VU Medical Center, The Netherlands
    J Neuroimmunol 187:179-86. 2007
  6. ncbi The rat macrophage scavenger receptor CD163: expression, regulation and role in inflammatory mediator production
    Machteld M J Polfliet
    Department of Molecular Cell Biology and Immunology, VU Medical Center, 1007 MB Amsterdam, The Netherlands
    Immunobiology 211:419-25. 2006
  7. ncbi The macrophage CD163 surface glycoprotein is an erythroblast adhesion receptor
    Babs O Fabriek
    Department of Molecular Cell Biology, Vrije Universiteit Medical Center, Amsterdam, The Netherlands
    Blood 109:5223-9. 2007

Detail Information

Publications7

  1. ncbi In vivo detection of myelin proteins in cervical lymph nodes of MS patients using ultrasound-guided fine-needle aspiration cytology
    Babs O Fabriek
    Department of Molecular Cell Biology and Immunology, VU Medical Center, P O Box 7057, 1007 MB Amsterdam, The Netherlands
    J Neuroimmunol 161:190-4. 2005
    ..This novel approach allows investigation of the first draining site of the brain for in vivo analysis of the immune regulation of MS...
  2. ncbi CD163-positive perivascular macrophages in the human CNS express molecules for antigen recognition and presentation
    Babs O Fabriek
    Department of Molecular Cell Biology and Immunology, VU Medical Center, Amsterdam, The Netherlands
    Glia 51:297-305. 2005
    ..Therefore PVM, which occupy a strategic location at the BBB, are equipped to recognize antigen and present it to T cells, supporting a role in the regulation of perivascular inflammation in the human CNS...
  3. ncbi The macrophage scavenger receptor CD163
    Babs O Fabriek
    Department of Molecular Cell Biology and Immunology, VU Medical Center, P O Box 7057, 1007MB Amsterdam, The Netherlands
    Immunobiology 210:153-60. 2005
    ..Furthermore, it has been suggested that CD163 positive macrophages or the soluble form of CD163 plays a role in the resolution of inflammation, as they are found in high numbers in inflamed tissue...
  4. ncbi The macrophage scavenger receptor CD163 functions as an innate immune sensor for bacteria
    Babs O Fabriek
    Department of Molecular Cell Biology and Immunology, VU Medical Center, Amsterdam
    Blood 113:887-92. 2009
    ..These findings identify CD163 as a macrophage receptor for bacteria and suggest that, during bacterial infection, CD163 on resident tissue macrophages acts as an innate immune sensor and inducer of local inflammation...
  5. ncbi Proteolytic shedding of the macrophage scavenger receptor CD163 in multiple sclerosis
    Babs O Fabriek
    Department of Molecular Cell Biology and Immunology, VU Medical Center, The Netherlands
    J Neuroimmunol 187:179-86. 2007
    ..Collectively, our results provide evidence for proteolytic shedding of CD163 in MS and suggest a possible link to cytokine production...
  6. ncbi The rat macrophage scavenger receptor CD163: expression, regulation and role in inflammatory mediator production
    Machteld M J Polfliet
    Department of Molecular Cell Biology and Immunology, VU Medical Center, 1007 MB Amsterdam, The Netherlands
    Immunobiology 211:419-25. 2006
    ..Collectively, our findings identify rat CD163 as a broadly expressed macrophage scavenger receptor that may play a role in the activation of mphi during hemolytic and/or inflammatory conditions...
  7. ncbi The macrophage CD163 surface glycoprotein is an erythroblast adhesion receptor
    Babs O Fabriek
    Department of Molecular Cell Biology, Vrije Universiteit Medical Center, Amsterdam, The Netherlands
    Blood 109:5223-9. 2007
    ..These findings identify CD163 on macrophages as an adhesion receptor for erythroblasts in erythroblastic islands, and suggest a regulatory role for CD163 during erythropoiesis...