Leontien Diergaarde

Summary

Affiliation: VU University Medical Center
Country: The Netherlands

Publications

  1. ncbi request reprint Poor impulse control predicts inelastic demand for nicotine but not alcohol in rats
    Leontien Diergaarde
    Department of Anatomy and Neurosciences, VU University Medical Center, Neuroscience Campus Amsterdam, The Netherlands
    Addict Biol 17:576-87. 2012
  2. ncbi request reprint Pharmacological manipulation of memory reconsolidation: towards a novel treatment of pathogenic memories
    Leontien Diergaarde
    Department of Anatomy and Neurosciences, Center for Neurogenomics and Cognitive Research, VU Medical Center, Van der Boechorststraat 7, 1081 BT Amsterdam, The Netherlands
    Eur J Pharmacol 585:453-7. 2008
  3. ncbi request reprint Early amygdala damage disrupts performance on medial prefrontal cortex-related tasks but spares spatial learning and memory in the rat
    L Diergaarde
    Rudolf Magnus Institute of Neuroscience, Department of Pharmacology and Anatomy, University Medical Center Utrecht, P O box 80040, 3508 TA Utrecht, The Netherlands
    Neuroscience 130:581-90. 2005
  4. ncbi request reprint Neonatal amygdala lesions affect appetitive motivational and consummatory aspects of social behavior in the rat
    Leontien Diergaarde
    Rudolf Magnus Institute of Neuroscience, Department of Pharmacology and Anatomy, University Medical Center Utrecht, Utrecht, Netherlands
    Behav Neurosci 119:814-20. 2005
  5. ncbi request reprint Beta-adrenoceptor mediated inhibition of long-term reward-related memory reconsolidation
    Leontien Diergaarde
    Research Institute Neurosciences Vrije Universiteit, Center for Neurogenomics and Cognitive Research, Department of Anatomy and Neurosciences, VU Medical Center, Van der Boechorststraat 7, 1081 BT Amsterdam, The Netherlands
    Behav Brain Res 170:333-6. 2006
  6. ncbi request reprint Impulsive choice and impulsive action predict vulnerability to distinct stages of nicotine seeking in rats
    Leontien Diergaarde
    Center for Neurogenomics and Cognitive Research, Department of Anatomy and Neurosciences, VU Medical Center, Amsterdam, The Netherlands
    Biol Psychiatry 63:301-8. 2008
  7. ncbi request reprint Contextual renewal of nicotine seeking in rats and its suppression by the cannabinoid-1 receptor antagonist Rimonabant (SR141716A)
    L Diergaarde
    Department of Anatomy and Neurosciences, VU Medical Center, 1081 BT Amsterdam, The Netherlands
    Neuropharmacology 55:712-6. 2008
  8. ncbi request reprint Trait impulsivity predicts escalation of sucrose seeking and hypersensitivity to sucrose-associated stimuli
    Leontien Diergaarde
    Department of Anatomy and Neurosciences, Vrije Universiteit Medical Center, Amsterdam, The Netherlands
    Behav Neurosci 123:794-803. 2009
  9. pmc Trait impulsive choice predicts resistance to extinction and propensity to relapse to cocaine seeking: a bidirectional investigation
    Nienke Broos
    Department of Anatomy and Neurosciences, Neuroscience Campus Amsterdam, VU University Medical Center, Amsterdam, The Netherlands
    Neuropsychopharmacology 37:1377-86. 2012
  10. ncbi request reprint Neonatal amygdala lesions and juvenile isolation in the rat: differential effects on locomotor and social behavior later in life
    Leontien Diergaarde
    Department of Pharmacology and Anatomy, Rudolf Magnus Institute of Neuroscience, University Medical Center Utrecht, Utrecht, Netherlands
    Behav Neurosci 118:298-305. 2004

Collaborators

Detail Information

Publications11

  1. ncbi request reprint Poor impulse control predicts inelastic demand for nicotine but not alcohol in rats
    Leontien Diergaarde
    Department of Anatomy and Neurosciences, VU University Medical Center, Neuroscience Campus Amsterdam, The Netherlands
    Addict Biol 17:576-87. 2012
    ..Our model seems well suited for studying nicotine and alcohol demand in rats and, as such, might contribute to our understanding of tobacco and alcohol dependence...
  2. ncbi request reprint Pharmacological manipulation of memory reconsolidation: towards a novel treatment of pathogenic memories
    Leontien Diergaarde
    Department of Anatomy and Neurosciences, Center for Neurogenomics and Cognitive Research, VU Medical Center, Van der Boechorststraat 7, 1081 BT Amsterdam, The Netherlands
    Eur J Pharmacol 585:453-7. 2008
    ....
  3. ncbi request reprint Early amygdala damage disrupts performance on medial prefrontal cortex-related tasks but spares spatial learning and memory in the rat
    L Diergaarde
    Rudolf Magnus Institute of Neuroscience, Department of Pharmacology and Anatomy, University Medical Center Utrecht, P O box 80040, 3508 TA Utrecht, The Netherlands
    Neuroscience 130:581-90. 2005
    ..Together, these results indicate that neonatal BLA damage affects species-specific sequential behavior and flexibility, which may be attributed to abnormal functioning of the mPFC...
  4. ncbi request reprint Neonatal amygdala lesions affect appetitive motivational and consummatory aspects of social behavior in the rat
    Leontien Diergaarde
    Rudolf Magnus Institute of Neuroscience, Department of Pharmacology and Anatomy, University Medical Center Utrecht, Utrecht, Netherlands
    Behav Neurosci 119:814-20. 2005
    ..Finally, the reported deficits in AMX-PD 7 rats may reflect neurodevelopmental deficits of structures connected with the amygdala...
  5. ncbi request reprint Beta-adrenoceptor mediated inhibition of long-term reward-related memory reconsolidation
    Leontien Diergaarde
    Research Institute Neurosciences Vrije Universiteit, Center for Neurogenomics and Cognitive Research, Department of Anatomy and Neurosciences, VU Medical Center, Van der Boechorststraat 7, 1081 BT Amsterdam, The Netherlands
    Behav Brain Res 170:333-6. 2006
    ..PROP administration upon reactivation reduced sucrose seeking behaviour 3 weeks post-training, indicating that reconsolidation of reward-related memories can be disrupted after a long post-training interval...
  6. ncbi request reprint Impulsive choice and impulsive action predict vulnerability to distinct stages of nicotine seeking in rats
    Leontien Diergaarde
    Center for Neurogenomics and Cognitive Research, Department of Anatomy and Neurosciences, VU Medical Center, Amsterdam, The Netherlands
    Biol Psychiatry 63:301-8. 2008
    ..Although heavy smoking has been associated with impulsivity in humans, it is not clear whether poor impulse control represents a risk factor in the etiology of nicotine dependence...
  7. ncbi request reprint Contextual renewal of nicotine seeking in rats and its suppression by the cannabinoid-1 receptor antagonist Rimonabant (SR141716A)
    L Diergaarde
    Department of Anatomy and Neurosciences, VU Medical Center, 1081 BT Amsterdam, The Netherlands
    Neuropharmacology 55:712-6. 2008
    ..Further, our results indicate that the endocannabinoid system is involved in context-induced relapse to nicotine seeking, and as such these data provide further evidence for the use of CB1 antagonists in smoking cessation...
  8. ncbi request reprint Trait impulsivity predicts escalation of sucrose seeking and hypersensitivity to sucrose-associated stimuli
    Leontien Diergaarde
    Department of Anatomy and Neurosciences, Vrije Universiteit Medical Center, Amsterdam, The Netherlands
    Behav Neurosci 123:794-803. 2009
    ..As such, elevated impulsivity might constitute a risk factor for the initiation and maintenance of addictive behaviors...
  9. pmc Trait impulsive choice predicts resistance to extinction and propensity to relapse to cocaine seeking: a bidirectional investigation
    Nienke Broos
    Department of Anatomy and Neurosciences, Neuroscience Campus Amsterdam, VU University Medical Center, Amsterdam, The Netherlands
    Neuropsychopharmacology 37:1377-86. 2012
    ..These observations suggest that trait impulsivity can be used as a predictive factor for addiction liability, but treating this impulsivity does not necessarily protect against relapse...
  10. ncbi request reprint Neonatal amygdala lesions and juvenile isolation in the rat: differential effects on locomotor and social behavior later in life
    Leontien Diergaarde
    Department of Pharmacology and Anatomy, Rudolf Magnus Institute of Neuroscience, University Medical Center Utrecht, Utrecht, Netherlands
    Behav Neurosci 118:298-305. 2004
    ..These results suggest that a combination of neonatal amygdala damage and juvenile isolation may serve as an animal model of certain psychopathological neurodevelopmental disorders, such as autism...
  11. pmc Disruption of Long-Term Alcohol-Related Memory Reconsolidation: Role of β-Adrenoceptors and NMDA Receptors
    Jelte A Wouda
    Department of Anatomy and Neurosciences, VU University Medical Center, Neuroscience Campus Amsterdam Amsterdam, Netherlands
    Front Behav Neurosci 4:179. 2010
    ....