Debby den Uyl

Summary

Affiliation: VU University Medical Center
Country: The Netherlands

Publications

  1. doi request reprint Low grade inflammation is associated with lower velocity of sound and broadband ultrasound attenuation in older men, but not with bone loss or fracture risk in a longitudinal aging study
    Debby den Uyl
    Amsterdam Rheumatology and Immunology Center, VU University Medical Center and Reade, The Netherlands Electronic address
    Bone 81:270-6. 2015
  2. ncbi request reprint Glucocorticoid-induced osteoporosis
    D den Uyl
    VU University Medical Center, Department of Rheumatology, 1081 HV Amsterdam, The Netherlands
    Clin Exp Rheumatol 29:S93-8. 2011
  3. pmc Advances in glucocorticoid-induced osteoporosis
    Debby den Uyl
    Department of Rheumatology, VU University Medical Center, De Boelelaan 1117, 1081 HV, Amsterdam, The Netherlands
    Curr Rheumatol Rep 13:233-40. 2011
  4. doi request reprint Effective Treatment for Rapid Improvement of Both Disease Activity and Self-Reported Physical Activity in Early Rheumatoid Arthritis
    Nicole P C Konijn
    VU University Medical Center, Amsterdam, The Netherlands
    Arthritis Care Res (Hoboken) 68:280-4. 2016
  5. doi request reprint Intensive combination treatment regimens, including prednisolone, are effective in treating patients with early rheumatoid arthritis regardless of additional etanercept: 1-year results of the COBRA-light open-label, randomised, non-inferiority trial
    Marieke M ter Wee
    Department of Rheumatology, VU University Medical Center, Amsterdam, Noord Holland, The Netherlands
    Ann Rheum Dis 74:1233-40. 2015
  6. doi request reprint Subclinical synovitis detected by macrophage PET, but not MRI, is related to short-term flare of clinical disease activity in early RA patients: an exploratory study
    Yoony Y J Gent
    Department of Rheumatology, VU University Medical Center, De Boelelaan 1117, PO Box 7057, Amsterdam, 1081, HV, The Netherlands
    Arthritis Res Ther 17:266. 2015
  7. pmc (Sub)clinical cardiovascular disease is associated with increased bone loss and fracture risk; a systematic review of the association between cardiovascular disease and osteoporosis
    Debby den Uyl
    Department of Rheumatology, VU Medical Centre, De Boelelaan 1117, 1081 NV Amsterdam, The Netherlands
    Arthritis Res Ther 13:R5. 2011
  8. doi request reprint Metabolic effects of high-dose prednisolone treatment in early rheumatoid arthritis: balance between diabetogenic effects and inflammation reduction
    Debby den Uyl
    VU University Medical Center, Amsterdam, The Netherlands
    Arthritis Rheum 64:639-46. 2012
  9. pmc A non-inferiority trial of an attenuated combination strategy ('COBRA-light') compared to the original COBRA strategy: clinical results after 26 weeks
    Debby den Uyl
    Department of Rheumatology, VU University Medical Center, Amsterdam, The Netherlands
    Ann Rheum Dis 73:1071-8. 2014
  10. doi request reprint Inactivating PSMB5 mutations and P-glycoprotein (multidrug resistance-associated protein/ATP-binding cassette B1) mediate resistance to proteasome inhibitors: ex vivo efficacy of (immuno)proteasome inhibitors in mononuclear blood cells from patients with
    Sue Ellen Verbrugge
    Department of Rheumatology, VU Institute for Cancer and Immunology, De Boelelaan 1117, 1081 HV, Amsterdam, The Netherlands
    J Pharmacol Exp Ther 341:174-82. 2012

Collaborators

Detail Information

Publications11

  1. doi request reprint Low grade inflammation is associated with lower velocity of sound and broadband ultrasound attenuation in older men, but not with bone loss or fracture risk in a longitudinal aging study
    Debby den Uyl
    Amsterdam Rheumatology and Immunology Center, VU University Medical Center and Reade, The Netherlands Electronic address
    Bone 81:270-6. 2015
    ..Our objective was to investigate whether low grade systemic inflammation was associated with bone markers, bone quality, bone mass and fracture risk in a population of older persons...
  2. ncbi request reprint Glucocorticoid-induced osteoporosis
    D den Uyl
    VU University Medical Center, Department of Rheumatology, 1081 HV Amsterdam, The Netherlands
    Clin Exp Rheumatol 29:S93-8. 2011
    ..Different treatment options are summarised considering the pathogenesis of glucocorticoid-induced osteoporosis. Improved insights into pathogenesis might result in development of new treatment possibilities...
  3. pmc Advances in glucocorticoid-induced osteoporosis
    Debby den Uyl
    Department of Rheumatology, VU University Medical Center, De Boelelaan 1117, 1081 HV, Amsterdam, The Netherlands
    Curr Rheumatol Rep 13:233-40. 2011
    ....
  4. doi request reprint Effective Treatment for Rapid Improvement of Both Disease Activity and Self-Reported Physical Activity in Early Rheumatoid Arthritis
    Nicole P C Konijn
    VU University Medical Center, Amsterdam, The Netherlands
    Arthritis Care Res (Hoboken) 68:280-4. 2016
    ..To investigate the longitudinal relationship between disease activity and self-reported physical activity (PA) in patients with early rheumatoid arthritis during the first year of treatment with combination therapy...
  5. doi request reprint Intensive combination treatment regimens, including prednisolone, are effective in treating patients with early rheumatoid arthritis regardless of additional etanercept: 1-year results of the COBRA-light open-label, randomised, non-inferiority trial
    Marieke M ter Wee
    Department of Rheumatology, VU University Medical Center, Amsterdam, Noord Holland, The Netherlands
    Ann Rheum Dis 74:1233-40. 2015
    ..5 mg/week, sulfasalazine 2 g/day, with initial prednisolone 60 mg/day) after 26 weeks in patients with early active rheumatoid arthritis (RA)...
  6. doi request reprint Subclinical synovitis detected by macrophage PET, but not MRI, is related to short-term flare of clinical disease activity in early RA patients: an exploratory study
    Yoony Y J Gent
    Department of Rheumatology, VU University Medical Center, De Boelelaan 1117, PO Box 7057, Amsterdam, 1081, HV, The Netherlands
    Arthritis Res Ther 17:266. 2015
    ....
  7. pmc (Sub)clinical cardiovascular disease is associated with increased bone loss and fracture risk; a systematic review of the association between cardiovascular disease and osteoporosis
    Debby den Uyl
    Department of Rheumatology, VU Medical Centre, De Boelelaan 1117, 1081 NV Amsterdam, The Netherlands
    Arthritis Res Ther 13:R5. 2011
    ..The co-occurrence of cardiovascular disease and osteoporosis prompted us to review the evidence of an association between cardiovascular (CV) disease and osteoporosis and potential shared common pathophysiological mechanisms...
  8. doi request reprint Metabolic effects of high-dose prednisolone treatment in early rheumatoid arthritis: balance between diabetogenic effects and inflammation reduction
    Debby den Uyl
    VU University Medical Center, Amsterdam, The Netherlands
    Arthritis Rheum 64:639-46. 2012
    ..To investigate the dose-related effects of glucocorticoid treatment on glucose tolerance, beta cell function, and insulin sensitivity in patients with early active rheumatoid arthritis (RA)...
  9. pmc A non-inferiority trial of an attenuated combination strategy ('COBRA-light') compared to the original COBRA strategy: clinical results after 26 weeks
    Debby den Uyl
    Department of Rheumatology, VU University Medical Center, Amsterdam, The Netherlands
    Ann Rheum Dis 73:1071-8. 2014
    ..Attenuating the COBRA regimen might lessen concerns about side effects, but the efficacy of such strategies is unknown...
  10. doi request reprint Inactivating PSMB5 mutations and P-glycoprotein (multidrug resistance-associated protein/ATP-binding cassette B1) mediate resistance to proteasome inhibitors: ex vivo efficacy of (immuno)proteasome inhibitors in mononuclear blood cells from patients with
    Sue Ellen Verbrugge
    Department of Rheumatology, VU Institute for Cancer and Immunology, De Boelelaan 1117, 1081 HV, Amsterdam, The Netherlands
    J Pharmacol Exp Ther 341:174-82. 2012
    ..These results indicate that the pharmacologic activity of these PIs may be hindered by drug resistance mechanisms involving PSMB5 mutations and PI extrusion via Pgp...
  11. pmc Patient preference and acceptability of calcium plus vitamin D3 supplementation: a randomised, open, cross-over trial
    Debby den Uyl
    Department of Rheumatology, VU Medical Centre, Room 3A58, P O Box 7057, 1007 MB, Amsterdam, The Netherlands
    Clin Rheumatol 29:465-72. 2010
    ..The two formulations were tolerated equally well. A significant greater number of patients considered the chewable tablet as preferable and acceptable to the sachet, containing calcium and vitamin D(3)...