Research Topics
| W de RondeSummaryAffiliation: VU University Medical Center Country: The Netherlands Publications
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Detail Information
Publications
Reduction in 24-hour plasma testosterone levels in subjects who showered 15 or 30 minutes after application of testosterone gelWillem de Ronde
Department of Endocrinology, VU University Medical Center, Amsterdam, The Netherlands
Pharmacotherapy 31:248-52. 2011..To investigate whether showering, to prevent the involuntary transfer of testosterone to others through skin contact, either 15 or 30 minutes after application of testosterone gel would significantly affect plasma testosterone levels...
Therapeutic uses of aromatase inhibitors in menWillem de Ronde
Department of Endocrinology, Vrije Universiteit Medical Center, Amsterdam, The Netherlands
Curr Opin Endocrinol Diabetes Obes 14:235-40. 2007..Potent aromatase inhibitors offer a convenient way to suppress estrogen production in men. This review aims to present an overview of the potential indications for aromatase inhibitors in men and to discuss results of clinical trials...- [Use of androgenic anabolic steroids before and during the Olympic Games: less but has not died out]W de Ronde
VU Medisch Centrum, Afd Endocrinologie, De Boelelaan 1117, 1081 HV Amsterdam
Ned Tijdschr Geneeskd 152:1820-4. 2008..The performance-enhancing effects of doping and the introduction of intensive doping surveillance are reflected in the decline in performance in several women's track and field events... - [Some new aspects of the Klinefelter syndrome]L J G Gooren
VU Medisch Centrum, Afd Endocrinologie, De Boelelaan III7, 108I HV Amsterdam
Ned Tijdschr Geneeskd 150:2693-6. 2006..New reproductive techniques no longer automatically mean that men with KS will remain infertile. Treatment with testosterone is in principle life-long to prevent osteoporosis and loss of muscle mass and strength... - Calculation of bioavailable and free testosterone in men: a comparison of 5 published algorithmsWillem de Ronde
Department of Endocrinology, Vrije Universiteit Medical Center, Amsterdam, The Netherlands
Clin Chem 52:1777-84. 2006..Estimation of serum concentrations of free testosterone (FT) and bioavailable testosterone (bioT) by calculation is an inexpensive and uncomplicated method. We compared results obtained with 5 different algorithms... - Hyperandrogenism after transfer of topical testosterone gel: case report and review of published and unpublished studiesWillem de Ronde
Department of Endocrinology, VU University Medical Center, De Boelelaan 1117, PO Box 7057, 1007 MB Amsterdam, The Netherlands
Hum Reprod 24:425-8. 2009..Thus, the potential of testosterone transfer in gel users should be recognized as a possible side effect of this form of testosterone replacement therapy... - Quality of life is reduced in patients with Klinefelter syndrome on androgen replacement therapyWillem de Ronde
Department of Endocrinology, Vrije Universiteit Medical Center, Amsterdam, The Netherlands
Eur J Endocrinol 160:465-8. 2009..Klinefelter syndrome (KS) is a genetic disorder, characterized by an XXY karyotype, hypergonadotrophic hypogonadism and infertility, which affects approximately 1 in 700 men. KS has also been associated with neuropsychological alterations... - Testosterone gel for the treatment of male hypogonadismWillem de Ronde
VU University Medical Center, Department of Endocrinology, De Boelelaan 1117, PO Box 7057, 1007 MB Amsterdam, The Netherlands
Expert Opin Biol Ther 9:249-53. 2009..Several modes of testosterone replacement are available including capsules, patches, injections, buccal tablets and gels... - A direct approach to the estimation of the origin of oestrogens and androgens in elderly men by comparison with hormone levels in postmenopausal womenWillem de Ronde
Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands
Eur J Endocrinol 152:261-8. 2005..From infusion studies with radioactively labelled hormones, we know that oestradiol (E2) and oestrone (E1) are either directly secreted by the testes and adrenal glands or peripherally produced from testicular or adrenal androgens... - ['Hungry bone' syndrome, characterized by prolonged symptomatic hypocalcemia, as a complication of the treatment for hyperthyroidism]W de Ronde
afd Inwendige Geneeskunde, sectie Endocrinologie, Erasmus Medisch Centrum, Rotterdam
Ned Tijdschr Geneeskd 148:231-4. 2004..In this patient, calcium suppletion led to normalisation of the serum calcium level two weeks postoperatively; she was discharged from the hospital in good condition after 3 weeks... - [Hormonal contraception in men]W de Ronde
VU Medisch Centrum, De Boelelaan 1117, 1081 HV Amsterdam
Ned Tijdschr Geneeskd 151:2558-61. 2007..It is not to be expected that male hormonal contraception will become a serious alternative to the already existing female equivalent during the coming 5 years... - Serum testosterone levels measured by isotope dilution-liquid chromatography-tandem mass spectrometry in postmenopausal women versus those in women who underwent bilateral oophorectomyHong N Bui
Department of Clinical Chemistry, VU University Medical Center, PO Box 7057, Amsterdam 1007MB, The Netherlands
Ann Clin Biochem 47:248-52. 2010.... - In men, peripheral estradiol levels directly reflect the action of estrogens at the hypothalamo-pituitary level to inhibit gonadotropin secretionGarrett Raven
Department of Endocrinology, VU University Medical Center, De Boelelaan 1117, P.O. Box 7057, 1007 MB Amsterdam, The Netherlands
J Clin Endocrinol Metab 91:3324-8. 2006..Peripheral estradiol levels directly reflect the inhibitory tone exerted by estrogens on gonadotropin release and are a major determinant of peripheral testosterone, LH, and FSH levels... - Associations of sex-hormone-binding globulin (SHBG) with non-SHBG-bound levels of testosterone and estradiol in independently living menWillem de Ronde
Department of Internal Medicine, Erasmus Medical Center, PO Box 1738, 3000 DR Rotterdam, The Netherlands
J Clin Endocrinol Metab 90:157-62. 2005..Therefore, we conclude that in eugonadal men, higher SHBG levels are associated with lower levels of non-SHBG-E2 but slightly higher levels of non-SHBG-T. This means that SHBG cannot be regarded as an estrogen amplifier in eugonadal men... - The importance of oestrogens in malesWillem de Ronde
Department of Internal Medicine, University Hospital Dijkzigt, Rotterdam, The Netherlands
Clin Endocrinol (Oxf) 58:529-42. 2003 - Serum levels of sex hormone-binding globulin (SHBG) are not associated with lower levels of non-SHBG-bound testosterone in male newborns and healthy adult menWillem de Ronde
Department of Internal Medicine, Erasmus Medical Center, 3000 DR Rotterdam, The Netherlands
Clin Endocrinol (Oxf) 62:498-503. 2005..Consequently the age related increase of SHBG does not account for the age related decline in non-SHBG-T in healthy adult men... - Effect of testosterone administration on serum and urine kallikrein concentrations in female-to-male transsexualsMargrita H Slagter
Department of Endocrinology, Vrije Universiteit University Medical Centre, Amsterdam, The Netherlands, and Department of Pathology and Laboratory Medicine, Mount Sinai Hospital, Toronto, ON, Canada
Clin Chem 52:1546-51. 2006.... - In young men, a moderate inhibition of testosterone synthesis capacity is only partly compensated by increased activity of the pituitary and the hypothalamusJorn Woerdeman
Department of Endocrinology, VU University Medical Center, Amsterdam, The Netherlands
Clin Endocrinol (Oxf) 72:76-80. 2010..The question arises as to whether such a compensation is complete or that decreased T synthesis may result in a lower plasma T concentration... - Endogenous sex hormones, sex hormone-binding globulin, and the risk of incident vertebral fractures in elderly men and women: the Rotterdam StudyHermien W Goderie-Plomp
Department of Internal Medicine, Erasmus Medical Center, P O Box 1738, 3000 DR Rotterdam, The Netherlands
J Clin Endocrinol Metab 89:3261-9. 2004..For men, no clear association was found, possibly due to insufficient power. No clear association between testosterone and incident vertebral fractures was observed in either men or women... - The association of sex hormone levels with quantitative ultrasound, bone mineral density, bone turnover and osteoporotic fractures in older men and womenNatalia O Kuchuk
Department of Endocrinology, VU University Medical Centre, 1007 MB Amsterdam, The Netherlands
Clin Endocrinol (Oxf) 67:295-303. 2007..Our objective was to examine whether serum oestradiol (E2) and testosterone (T) are associated with quantitative ultrasound (QUS), bone mineral density (BMD), bone turnover markers and fracture incidence... - Therapeutic effects of anabolic androgenic steroids on chronic diseases associated with muscle wastingJorn Woerdeman
VU University Medical Center, Department of Endocrinology, De Boelelaan 1117, PO Box 7057, 1007 MB Amsterdam, The Netherlands
Expert Opin Investig Drugs 20:87-97. 2011..Therefore, more studies are needed to confirm their long term safety and efficacy... - Serum and urine tissue kallikrein concentrations in male-to-female transsexuals treated with antiandrogens and estrogensMargrita H Slagter
Department of Endocrinology, VU University Medical Centre, Amsterdam, The Netherlands
Clin Chem 52:1356-65. 2006..The smaller responses of the other kallikreins presumably reflect their expression in multiple tissues... - Low free testosterone levels are associated with prevalence and incidence of depressive symptoms in older menDevina Joshi
EMGO Institute, VU University Medical Center, Amsterdam, The Netherlands
Clin Endocrinol (Oxf) 72:232-40. 2010..Our study analyses the cross-sectional association of testosterone levels with depressive symptoms and its prospective association with the development of incident depressive symptoms...