H C Comijs

..To investigate whether serum cortisol levels are associated with cognitive performance and cognitive decline in elderly persons and whether this association differs by age, sex, and depression status...

..In persons without memory complaints, persons with cardiovascular diseases or diabetes were at increased risk of dementia. Further research is necessary before these classification trees can be implemented in general health care...

..These findings further stress that careful clinical evaluation of cognitive functioning in older persons with these diseases is required in order to provide adequate care...

..With the aging of the population, the number of persons with cognitive impairment is likely to increase, and appropriate services should be available to them...

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..The study investigates whether persons who have experienced childhood adversity are more likely to develop depressive symptoms when faced with recent events...

..002) and memory functioning (p=.045). The results implicate that lower total cholesterol may be considered as a frailty marker, predictive of lower cognitive functioning in elderly...

..The present study investigates anxiety and depression in different phases of cognitive decline...

..To develop two classification models for use in primary care to aid early identification of persons at risk for persistent cognitive decline...

..The results implicate that a combination of both risk factors may be used as a marker for cognitive impairment...

..In the past 15 years, antidepressant use in adults has increased, mainly due to a rise in SSRI-use. The question is if this is true for older adults as well...

..This study investigates the effects of benzodiazepine (BZ) use on cognitive performance in elderly persons in a longitudinal design...

..The present study investigated whether symptoms of anxiety and depression predict decline of memory function in elderly people diagnosed with early stage AD...

..To assess whether serum levels of the inflammatory proteins alpha(1)-antichymotrypsin (ACT), C-reactive protein (CRP), interleukin-6 (IL-6), and albumin are associated with cognitive decline in older persons...

..To investigate whether depressive symptoms predict specific types of cognitive decline in order to elucidate the association between late life depression and cognitive decline...

..The authors investigated the relationship between anxiety and cognition in older persons, taking account of comorbid depression...

..Furthermore, it is investigated whether personality characteristics have a modifying effect on the association of memory complaints with depressive and anxiety symptoms and physical health...

..The beneficial role of social support, locus of control, and perceived self-efficacy on the level of psychological distress could be of importance in the development of future intervention programs...

..Prevalence, clinical features, risk factors and prognosis may change with AGE...

..Very little is known about the long term cognitive sequelae of bipolar disorder...

..To investigate to what extent subjective memory complaints and APOE-epsilon4 allele carriage predict future cognitive decline in cognitively intact elderly persons, by evaluating both their separate and combined effects...

..These findings are important for prevention of an intervention in cases of elder mistreatment...

..To examine long-term outcome of late-life anxiety disorders and utilization of mental health care services...

..Several concepts are described, with the neuropsychiatric features and predictors of conversion to dementia c.q. AD. Finally, consequences of preclinically diagnoses for health care are clarified...

..Based on the findings presented, some suggestions for this are given. Also, some directions for future research are described...

..To investigate the protective effect of NSAIDs and aspirin separately on cognitive decline in elderly subjects, controlling for consistent use of these agents over a prolonged period of time...

..Of this group, 44% recovered from cognitive decline or stayed stable in the next 3 years. Especially older age, memory complaints and an increase of cardiovascular diseases at follow-up predict further deterioration...

..The ongoing Longitudinal Aging Study Amsterdam has one pre-disaster and several post-disaster observations, making it possible to study changes in health, taking pre-disaster health characteristics into account...

..Whether conjugal bereavement also affects memory functioning has largely been unexamined. The present study investigates the effect of widowhood on memory functioning in older persons...

..However, it is not known what the roles of the individual components of the metabolic syndrome on cognition are...

..The aim of this study was to compare early-onset (EOD) and late-onset (LOD) depressive illness in a community-based sample...

..Insight into the individual care needs of the growing number of people with dementia is necessary to deliver more customized care. Our study aims to provide an overview of the literature on the subjective needs of people with dementia...

..We studied which features distinguish 'pure' anxiety disordered patients from those with co-morbid ASD...

..The data are inconsistent with regard to comorbidity as a distinct psychopathological entity. These findings are of great importance for treatment planning in patients with alcohol dependence and comorbid anxiety disorders...