Zoltan Bochdanovits

Summary

Affiliation: VU University Medical Center
Country: The Netherlands

Publications

  1. doi request reprint Empirical assessment of the validity of the 'fundamental theorem of the HapMap' in the light of 'cryptic' tagging of multiple susceptibility loci
    Zoltan Bochdanovits
    Section Medical Genomics, Department of Clinical Genetics, VUMC, Amsterdam, The Netherlands
    Eur J Hum Genet 16:525-9. 2008
  2. pmc Genome-wide prediction of functional gene-gene interactions inferred from patterns of genetic differentiation in mice and men
    Zoltan Bochdanovits
    Section Medical Genomics, Department of Clinical Genetics, Vrije Universiteit Medisch Centrum VUMC, Amsterdam, The Netherlands
    PLoS ONE 3:e1593. 2008
  3. doi request reprint A Functional polymorphism under positive evolutionary selection in ADRB2 is associated with human intelligence with opposite effects in the young and the elderly
    Zoltan Bochdanovits
    Department of Clinical Genetics, Section of Medical Genomics, VU Medical Center, Van der Boechorststraat 7, 1081 BT, Amsterdam, The Netherlands
    Behav Genet 39:15-23. 2009
  4. pmc A fine-mapping study of 7 top scoring genes from a GWAS for major depressive disorder
    Eva C Verbeek
    Department of Clinical Genetics, VU University Medical Center, Amsterdam, The Netherlands
    PLoS ONE 7:e37384. 2012
  5. pmc Variation at GRN 3'-UTR rs5848 is not associated with a risk of frontotemporal lobar degeneration in Dutch population
    Javier Simon-Sanchez
    Department of Clinical Genetics, Section of Medical Genomics, VU University Medical Centre, Amsterdam, The Netherlands
    PLoS ONE 4:e7494. 2009
  6. doi request reprint Transcriptional plasticity of a soil arthropod across different ecological conditions
    Tjalf E de Boer
    Department of Ecological Science, VU University, Amsterdam, The Netherlands
    Mol Ecol 20:1144-54. 2011
  7. pmc Global similarity with local differences in linkage disequilibrium between the Dutch and HapMap-CEU populations
    Luba Pardo
    Medical Genomics Section, Department of Clinical Genetics, Vrije University Medical Center, Amsterdam, The Netherlands
    Eur J Hum Genet 17:802-10. 2009
  8. doi request reprint Glucocorticoid receptor gene polymorphisms and childhood adversity are associated with depression: New evidence for a gene-environment interaction
    Pierre M Bet
    Department of Clinical Pharmacology and Pharmacy, VU University Medical Center, Amsterdam, The Netherlands
    Am J Med Genet B Neuropsychiatr Genet 150:660-9. 2009
  9. doi request reprint Cervical dystonia and genetic common variation in the dopamine pathway
    Justus L Groen
    Department of Neurology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    Parkinsonism Relat Disord 19:346-9. 2013
  10. doi request reprint The complete automation of cell culture: improvements for high-throughput and high-content screening
    Shushant Jain
    VUMC Clinical Genetics, Amsterdam, The Netherlands
    J Biomol Screen 16:932-9. 2011

Collaborators

Detail Information

Publications15

  1. doi request reprint Empirical assessment of the validity of the 'fundamental theorem of the HapMap' in the light of 'cryptic' tagging of multiple susceptibility loci
    Zoltan Bochdanovits
    Section Medical Genomics, Department of Clinical Genetics, VUMC, Amsterdam, The Netherlands
    Eur J Hum Genet 16:525-9. 2008
    ..On the basis of our results, a safe bet is to use a sample that is 10% larger than otherwise deemed necessary...
  2. pmc Genome-wide prediction of functional gene-gene interactions inferred from patterns of genetic differentiation in mice and men
    Zoltan Bochdanovits
    Section Medical Genomics, Department of Clinical Genetics, Vrije Universiteit Medisch Centrum VUMC, Amsterdam, The Netherlands
    PLoS ONE 3:e1593. 2008
    ....
  3. doi request reprint A Functional polymorphism under positive evolutionary selection in ADRB2 is associated with human intelligence with opposite effects in the young and the elderly
    Zoltan Bochdanovits
    Department of Clinical Genetics, Section of Medical Genomics, VU Medical Center, Van der Boechorststraat 7, 1081 BT, Amsterdam, The Netherlands
    Behav Genet 39:15-23. 2009
    ..This result illustrates the relevance of comparative genomics to detect genes that are involved in human behavior...
  4. pmc A fine-mapping study of 7 top scoring genes from a GWAS for major depressive disorder
    Eva C Verbeek
    Department of Clinical Genetics, VU University Medical Center, Amsterdam, The Netherlands
    PLoS ONE 7:e37384. 2012
    ..9E-7 but was not genome wide significant. Although our study did not identify a more strongly associated variant, the results for PCLO suggest that the causal variant is in high LD with rs2715147, rs2715148 and rs2522833...
  5. pmc Variation at GRN 3'-UTR rs5848 is not associated with a risk of frontotemporal lobar degeneration in Dutch population
    Javier Simon-Sanchez
    Department of Clinical Genetics, Section of Medical Genomics, VU University Medical Centre, Amsterdam, The Netherlands
    PLoS ONE 4:e7494. 2009
    ....
  6. doi request reprint Transcriptional plasticity of a soil arthropod across different ecological conditions
    Tjalf E de Boer
    Department of Ecological Science, VU University, Amsterdam, The Netherlands
    Mol Ecol 20:1144-54. 2011
    ..candida strongly responds. The broad range of conditions over which this soil-living detritivore is able to survive and reproduce, indicates a strategy of high plasticity, which comes with extensive gene expression regulation...
  7. pmc Global similarity with local differences in linkage disequilibrium between the Dutch and HapMap-CEU populations
    Luba Pardo
    Medical Genomics Section, Department of Clinical Genetics, Vrije University Medical Center, Amsterdam, The Netherlands
    Eur J Hum Genet 17:802-10. 2009
    ..This poor concordance in LD block structure suggests that large samples are required for robust estimations of local LD block structure in populations...
  8. doi request reprint Glucocorticoid receptor gene polymorphisms and childhood adversity are associated with depression: New evidence for a gene-environment interaction
    Pierre M Bet
    Department of Clinical Pharmacology and Pharmacy, VU University Medical Center, Amsterdam, The Netherlands
    Am J Med Genet B Neuropsychiatr Genet 150:660-9. 2009
    ..This G x E interaction also influenced HPA-axis markers providing support for the involvement of the HPA-axis in both stress regulation and the pathogenesis of depression...
  9. doi request reprint Cervical dystonia and genetic common variation in the dopamine pathway
    Justus L Groen
    Department of Neurology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    Parkinsonism Relat Disord 19:346-9. 2013
    ..Possibly, risk alleles in this pathway may be rarer than detectable in this study, or might be located in downstream dopamine signaling pathway. Alternatively, found dopamine level changes are secondary to the dystonia disease processes...
  10. doi request reprint The complete automation of cell culture: improvements for high-throughput and high-content screening
    Shushant Jain
    VUMC Clinical Genetics, Amsterdam, The Netherlands
    J Biomol Screen 16:932-9. 2011
    ..The authors demonstrate that such a system is able to successfully maintain different cell lines in culture for extended periods of time as well as significantly increasing throughput, accuracy, and reproducibility of HT and HC screens...
  11. doi request reprint Adaptive differences in gene expression associated with heavy metal tolerance in the soil arthropod Orchesella cincta
    Dick Roelofs
    Institute of Ecological Science, VU University Amsterdam, Amsterdam, The Netherlands
    Mol Ecol 18:3227-39. 2009
    ..We confirmed the micro-evolutionary processes occurring in soil arthropod populations and suggest a major contribution of gene regulation to the evolution of a stress-adapted phenotype...
  12. pmc Genome-wide association study confirms extant PD risk loci among the Dutch
    Javier Simon-Sanchez
    Department of Clinical Genetics, Section of Medical Genomics, VU University Medical Centre, Amsterdam, The Netherlands
    Eur J Hum Genet 19:655-61. 2011
    ..22 × 10(-4), OR = 1.51; HLA, rs4248166: P = 4.39 × 10(-5), OR = 1.36; and MAPT, rs3785880: P = 1.9 × 10(-3), OR = 1.19)...
  13. pmc Modulatory effects of the piccolo genotype on emotional memory in health and depression
    Saskia Woudstra
    Department of Psychiatry, VU University Medical Center, Amsterdam, The Netherlands
    PLoS ONE 8:e61494. 2013
    ....
  14. pmc Do consanguineous parents of a child affected by an autosomal recessive disease have more DNA identical-by-descent than similarly-related parents with healthy offspring? Design of a case-control study
    Marieke E Teeuw
    Department of Clinical Genetics, Section Community Genetics, EMGO Institute for Health and Care Research, VU University Medical Center, Amsterdam, The Netherlands
    BMC Med Genet 11:113. 2010
    ....
  15. pmc Comprehensive mRNA expression profiling distinguishes tauopathies and identifies shared molecular pathways
    Iraad F Bronner
    Section Medical Genomics, Department of Clinical Genetics, VU University Medical Center, and Center for Neurogenomics and Cognitive Research, VU University Medical Center and VU University, Amsterdam, The Netherlands
    PLoS ONE 4:e6826. 2009
    ....