Jovanka Bestebroer

Summary

Affiliation: VU University Medical Center
Country: The Netherlands

Publications

  1. doi How microorganisms avoid phagocyte attraction
    Jovanka Bestebroer
    Department of Medical Microbiology, VU Medical Center, Amsterdam, The Netherlands
    FEMS Microbiol Rev 34:395-414. 2010
  2. pmc Functional basis for complement evasion by staphylococcal superantigen-like 7
    Jovanka Bestebroer
    Department of Medical Microbiology, University Medical Center Utrecht, 3584 CX Utrecht, The Netherlands
    Cell Microbiol 12:1506-16. 2010
  3. doi Staphylococcal SSL5 inhibits leukocyte activation by chemokines and anaphylatoxins
    Jovanka Bestebroer
    Medical Microbiology, University Medical Center Utrecht, Utrecht, The Netherlands
    Blood 113:328-37. 2009
  4. doi A homolog of formyl peptide receptor-like 1 (FPRL1) inhibitor from Staphylococcus aureus (FPRL1 inhibitory protein) that inhibits FPRL1 and FPR
    Cristina Prat
    Medical Microbiology, University Medical Center Utrecht, Utrecht, The Netherlands
    J Immunol 183:6569-78. 2009
  5. ncbi Staphylococcal superantigen-like 5 binds PSGL-1 and inhibits P-selectin-mediated neutrophil rolling
    Jovanka Bestebroer
    Experimental Microbiology, University Medical Center Utrecht, The Netherlands
    Blood 109:2936-43. 2007
  6. doi Staphylococcus aureus proteins SSL6 and SElX interact with neutrophil receptors as identified using secretome phage display
    Cindy Fevre
    Department of Medical Microbiology, University Medical Center Utrecht, PO G04 614, Heidelberglaan 100, 3584 CX, Utrecht, The Netherlands
    Cell Microbiol 16:1646-65. 2014
  7. ncbi A new staphylococcal anti-inflammatory protein that antagonizes the formyl peptide receptor-like 1
    Cristina Prat
    Eijkman Winkler Institute, University Medical Center Utrecht, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands
    J Immunol 177:8017-26. 2006
  8. doi Composition of the type VII secretion system membrane complex
    Edith N G Houben
    Department of Medical Microbiology and Infection Control, VU University Medical Center, Amsterdam, The Netherlands
    Mol Microbiol 86:472-84. 2012

Collaborators

Detail Information

Publications8

  1. doi How microorganisms avoid phagocyte attraction
    Jovanka Bestebroer
    Department of Medical Microbiology, VU Medical Center, Amsterdam, The Netherlands
    FEMS Microbiol Rev 34:395-414. 2010
    ..As the large arsenal of GPCR modulators aids prolonged microbial persistence in the host, their study provides us a better understanding of microbial pathogenesis...
  2. pmc Functional basis for complement evasion by staphylococcal superantigen-like 7
    Jovanka Bestebroer
    Department of Medical Microbiology, University Medical Center Utrecht, 3584 CX Utrecht, The Netherlands
    Cell Microbiol 12:1506-16. 2010
    ..Finally, SSL7 effects were also demonstrated in vivo. In a murine model of immune complex peritonitis, SSL7 abrogated the C5a-driven influx of neutrophils in mouse peritoneum...
  3. doi Staphylococcal SSL5 inhibits leukocyte activation by chemokines and anaphylatoxins
    Jovanka Bestebroer
    Medical Microbiology, University Medical Center Utrecht, Utrecht, The Netherlands
    Blood 113:328-37. 2009
    ..It is therefore a potential new antiinflammatory compound for diseases associated with chemoattractants and their receptors and disorders characterized by excessive recruitment of leukocytes...
  4. doi A homolog of formyl peptide receptor-like 1 (FPRL1) inhibitor from Staphylococcus aureus (FPRL1 inhibitory protein) that inhibits FPRL1 and FPR
    Cristina Prat
    Medical Microbiology, University Medical Center Utrecht, Utrecht, The Netherlands
    J Immunol 183:6569-78. 2009
    ..In conclusion, the newly described excreted protein from S. aureus, FLIPr-like, is a potent inhibitor of the FPR- and FPRL1-mediated neutrophil responses and may be used to selectively modulate these chemoattractant receptors...
  5. ncbi Staphylococcal superantigen-like 5 binds PSGL-1 and inhibits P-selectin-mediated neutrophil rolling
    Jovanka Bestebroer
    Experimental Microbiology, University Medical Center Utrecht, The Netherlands
    Blood 109:2936-43. 2007
    ..This makes SSL5 a potential lead for the development of new anti-inflammatory compounds for disorders characterized by excessive recruitment of leukocytes...
  6. doi Staphylococcus aureus proteins SSL6 and SElX interact with neutrophil receptors as identified using secretome phage display
    Cindy Fevre
    Department of Medical Microbiology, University Medical Center Utrecht, PO G04 614, Heidelberglaan 100, 3584 CX, Utrecht, The Netherlands
    Cell Microbiol 16:1646-65. 2014
    ..Our findings provide new insights into the pathogenesis of S. aureus infections and support phage display as an efficient method to identify bacterial secretome proteins interacting with humoral or cellular immune components. ..
  7. ncbi A new staphylococcal anti-inflammatory protein that antagonizes the formyl peptide receptor-like 1
    Cristina Prat
    Eijkman Winkler Institute, University Medical Center Utrecht, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands
    J Immunol 177:8017-26. 2006
    ..aureus infections. As a novel described FPRL1 antagonist, it might lead to the development of therapeutic agents in FPRL1-mediated inflammatory components of diseases such as systemic amyloidosis, Alzheimer's, and prion disease...
  8. doi Composition of the type VII secretion system membrane complex
    Edith N G Houben
    Department of Medical Microbiology and Infection Control, VU University Medical Center, Amsterdam, The Netherlands
    Mol Microbiol 86:472-84. 2012
    ..These are the first data on a T7S membrane complex and, given the high conservation of its components, our data can likely be generalized to most mycobacterial T7S systems...