Jovanka Bestebroer

Summary

Affiliation: VU University Medical Center
Country: The Netherlands

Publications

  1. ncbi How microorganisms avoid phagocyte attraction
    Jovanka Bestebroer
    Department of Medical Microbiology, VU Medical Center, Amsterdam, The Netherlands
    FEMS Microbiol Rev 34:395-414. 2010
  2. ncbi Functional basis for complement evasion by staphylococcal superantigen-like 7
    Jovanka Bestebroer
    Department of Medical Microbiology, University Medical Center Utrecht, 3584 CX Utrecht, The Netherlands
    Cell Microbiol 12:1506-16. 2010
  3. ncbi Staphylococcal SSL5 inhibits leukocyte activation by chemokines and anaphylatoxins
    Jovanka Bestebroer
    Medical Microbiology, University Medical Center Utrecht, Utrecht, The Netherlands
    Blood 113:328-37. 2009
  4. ncbi A homolog of formyl peptide receptor-like 1 (FPRL1) inhibitor from Staphylococcus aureus (FPRL1 inhibitory protein) that inhibits FPRL1 and FPR
    Cristina Prat
    Medical Microbiology, University Medical Center Utrecht, Utrecht, The Netherlands
    J Immunol 183:6569-78. 2009
  5. ncbi Staphylococcal superantigen-like 5 binds PSGL-1 and inhibits P-selectin-mediated neutrophil rolling
    Jovanka Bestebroer
    Experimental Microbiology, University Medical Center Utrecht, The Netherlands
    Blood 109:2936-43. 2007
  6. ncbi A new staphylococcal anti-inflammatory protein that antagonizes the formyl peptide receptor-like 1
    Cristina Prat
    Eijkman Winkler Institute, University Medical Center Utrecht, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands
    J Immunol 177:8017-26. 2006
  7. ncbi Composition of the type VII secretion system membrane complex
    Edith N G Houben
    Department of Medical Microbiology and Infection Control, VU University Medical Center, Amsterdam, The Netherlands
    Mol Microbiol 86:472-84. 2012

Collaborators

Detail Information

Publications7

  1. ncbi How microorganisms avoid phagocyte attraction
    Jovanka Bestebroer
    Department of Medical Microbiology, VU Medical Center, Amsterdam, The Netherlands
    FEMS Microbiol Rev 34:395-414. 2010
    ..As the large arsenal of GPCR modulators aids prolonged microbial persistence in the host, their study provides us a better understanding of microbial pathogenesis...
  2. ncbi Functional basis for complement evasion by staphylococcal superantigen-like 7
    Jovanka Bestebroer
    Department of Medical Microbiology, University Medical Center Utrecht, 3584 CX Utrecht, The Netherlands
    Cell Microbiol 12:1506-16. 2010
    ..Finally, SSL7 effects were also demonstrated in vivo. In a murine model of immune complex peritonitis, SSL7 abrogated the C5a-driven influx of neutrophils in mouse peritoneum...
  3. ncbi Staphylococcal SSL5 inhibits leukocyte activation by chemokines and anaphylatoxins
    Jovanka Bestebroer
    Medical Microbiology, University Medical Center Utrecht, Utrecht, The Netherlands
    Blood 113:328-37. 2009
    ..It is therefore a potential new antiinflammatory compound for diseases associated with chemoattractants and their receptors and disorders characterized by excessive recruitment of leukocytes...
  4. ncbi A homolog of formyl peptide receptor-like 1 (FPRL1) inhibitor from Staphylococcus aureus (FPRL1 inhibitory protein) that inhibits FPRL1 and FPR
    Cristina Prat
    Medical Microbiology, University Medical Center Utrecht, Utrecht, The Netherlands
    J Immunol 183:6569-78. 2009
    ..In conclusion, the newly described excreted protein from S. aureus, FLIPr-like, is a potent inhibitor of the FPR- and FPRL1-mediated neutrophil responses and may be used to selectively modulate these chemoattractant receptors...
  5. ncbi Staphylococcal superantigen-like 5 binds PSGL-1 and inhibits P-selectin-mediated neutrophil rolling
    Jovanka Bestebroer
    Experimental Microbiology, University Medical Center Utrecht, The Netherlands
    Blood 109:2936-43. 2007
    ..This makes SSL5 a potential lead for the development of new anti-inflammatory compounds for disorders characterized by excessive recruitment of leukocytes...
  6. ncbi A new staphylococcal anti-inflammatory protein that antagonizes the formyl peptide receptor-like 1
    Cristina Prat
    Eijkman Winkler Institute, University Medical Center Utrecht, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands
    J Immunol 177:8017-26. 2006
    ..aureus infections. As a novel described FPRL1 antagonist, it might lead to the development of therapeutic agents in FPRL1-mediated inflammatory components of diseases such as systemic amyloidosis, Alzheimer's, and prion disease...
  7. ncbi Composition of the type VII secretion system membrane complex
    Edith N G Houben
    Department of Medical Microbiology and Infection Control, VU University Medical Center, Amsterdam, The Netherlands
    Mol Microbiol 86:472-84. 2012
    ..These are the first data on a T7S membrane complex and, given the high conservation of its components, our data can likely be generalized to most mycobacterial T7S systems...