B J Appelmelk

Summary

Affiliation: VU University Medical Center
Country: The Netherlands

Publications

  1. pmc Helicobacter pylori modulates the T helper cell 1/T helper cell 2 balance through phase-variable interaction between lipopolysaccharide and DC-SIGN
    Mathijs P Bergman
    Department of Medical Microbiology and Infection Control, Vrije Universiteit Medical Center, 1081 BT Amsterdam, The Netherlands
    J Exp Med 200:979-90. 2004
  2. pmc Mycobacterium marinum MMAR_2380, a predicted transmembrane acyltransferase, is essential for the presence of the mannose cap on lipoarabinomannan
    Nicole N Driessen
    Department of Medical Microbiology and Infection Control, VU University Medical Center, 1081 BT Amsterdam, The Netherlands
    Microbiology 156:3492-502. 2010
  3. ncbi request reprint The mannose cap of mycobacterial lipoarabinomannan does not dominate the Mycobacterium-host interaction
    B J Appelmelk
    Department of Medical Microbiology and Infection Control, VU University Medical Center, 1081 BT Amsterdam, The Netherlands
    Cell Microbiol 10:930-44. 2008
  4. pmc Phase variation in Helicobacter pylori lipopolysaccharide due to changes in the lengths of poly(C) tracts in alpha3-fucosyltransferase genes
    B J Appelmelk
    Departments of Medical Microbiology, Vrije Universiteit, Medical School, 1081 BT Amsterdam, The Netherlands
    Infect Immun 67:5361-6. 1999
  5. pmc Phase variation in H type I and Lewis a epitopes of Helicobacter pylori lipopolysaccharide
    B J Appelmelk
    Department of Medical Microbiology, Vrije Universiteit, Medical School, 1081 BT Amsterdam, The Netherlands
    Infect Immun 68:5928-32. 2000
  6. ncbi request reprint Identification by Tn10 transposon mutagenesis of host factors involved in the biosynthesis of K99 fimbriae of Escherichia coli: effect of LPS core mutations
    E Pilipcinec
    Department of Microbiology and Immunology, University of Veterinary Medicine, Kosice, Slovak Republic
    FEMS Microbiol Lett 123:201-6. 1994
  7. pmc Antigastric autoantibodies in ferrets naturally infected with Helicobacter mustelae
    T O Cróinín
    The Children s Research Centre, Our Lady s Hospital for Sick Children, Crumlin, Ireland
    Infect Immun 69:2708-13. 2001

Collaborators

Detail Information

Publications7

  1. pmc Helicobacter pylori modulates the T helper cell 1/T helper cell 2 balance through phase-variable interaction between lipopolysaccharide and DC-SIGN
    Mathijs P Bergman
    Department of Medical Microbiology and Infection Control, Vrije Universiteit Medical Center, 1081 BT Amsterdam, The Netherlands
    J Exp Med 200:979-90. 2004
    ..Our data indicate a role for LPS phase variation and Le antigen expression by H. pylori in suppressing immune responses through DC-SIGN...
  2. pmc Mycobacterium marinum MMAR_2380, a predicted transmembrane acyltransferase, is essential for the presence of the mannose cap on lipoarabinomannan
    Nicole N Driessen
    Department of Medical Microbiology and Infection Control, VU University Medical Center, 1081 BT Amsterdam, The Netherlands
    Microbiology 156:3492-502. 2010
    ..Although the exact function of MMAR_2380 remains unknown, we show that the protein is essential for the presence of a mannose cap on LAM...
  3. ncbi request reprint The mannose cap of mycobacterial lipoarabinomannan does not dominate the Mycobacterium-host interaction
    B J Appelmelk
    Department of Medical Microbiology and Infection Control, VU University Medical Center, 1081 BT Amsterdam, The Netherlands
    Cell Microbiol 10:930-44. 2008
    ..bovis BCG did not survive less well in lung, spleen or liver and induced a similar cytokine profile. Our data contradict the current paradigm and demonstrate that mannose-capped LAM does not dominate the Mycobacterium-host interaction...
  4. pmc Phase variation in Helicobacter pylori lipopolysaccharide due to changes in the lengths of poly(C) tracts in alpha3-fucosyltransferase genes
    B J Appelmelk
    Departments of Medical Microbiology, Vrije Universiteit, Medical School, 1081 BT Amsterdam, The Netherlands
    Infect Immun 67:5361-6. 1999
    ..Finally, the data provide an understanding at the molecular level of the mechanisms underlying LPS diversity in H. pylori, which may play an important role in adaptation to the host...
  5. pmc Phase variation in H type I and Lewis a epitopes of Helicobacter pylori lipopolysaccharide
    B J Appelmelk
    Department of Medical Microbiology, Vrije Universiteit, Medical School, 1081 BT Amsterdam, The Netherlands
    Infect Immun 68:5928-32. 2000
    ..Our data provide understanding at the molecular level of how H. pylori is able to diversify in the host, a requirement likely essential for successful colonization and transmission...
  6. ncbi request reprint Identification by Tn10 transposon mutagenesis of host factors involved in the biosynthesis of K99 fimbriae of Escherichia coli: effect of LPS core mutations
    E Pilipcinec
    Department of Microbiology and Immunology, University of Veterinary Medicine, Kosice, Slovak Republic
    FEMS Microbiol Lett 123:201-6. 1994
    ..Preliminary experiments indicated that K99 major subunits, in contrast to K88 subunits, strongly bind LPS molecules...
  7. pmc Antigastric autoantibodies in ferrets naturally infected with Helicobacter mustelae
    T O Cróinín
    The Children s Research Centre, Our Lady s Hospital for Sick Children, Crumlin, Ireland
    Infect Immun 69:2708-13. 2001
    ..In conclusion, ferrets naturally infected with H. mustelae generate antibodies that react with parietal cells, but these autoantibodies are not due to molecular mimicry...