Affiliation: Vrije Universiteit
Country: The Netherlands
- Sustained attention and inhibition of cognitive interference in treated phenylketonuria: associations with concurrent and lifetime phenylalanine concentrationsS C J Huijbregts
Department of Clinical Neuropsychology, Vrije Universiteit Amsterdam, Van der Boechorststraat 1, 1081 BT, Amsterdam, The Netherlands
Neuropsychologia 40:7-15. 2002..We suggest that phe levels should be maintained under 360 micromol/l until approximately age 12, when development of attentional control approaches an adult level...
- The neuropsychological profile of early and continuously treated phenylketonuria: orienting, vigilance, and maintenance versus manipulation-functions of working memoryS C J Huijbregts
Department of Clinical Neuropsychology, Vrije Universiteit Amsterdam, Van der Boechorststraat 1, 1081 BT Amsterdam, The Netherlands
Neurosci Biobehav Rev 26:697-712. 2002..It is discussed how the specific neuropsychological impairments in PKU may be a consequence of mid-dorsolateral prefrontal cortex (DLPFC) dysfunctioning due to deficiencies in catecholamine modulation...
- Inhibition of prepotent responding and attentional flexibility in treated phenylketonuriaStephan Huijbregts
Department of Clinical Neuropsychology, Free University of Amsterdam, The Netherlands
Dev Neuropsychol 22:481-99. 2002..However, based on the evidence that development of specific executive functions continues until approximately age 12, it is recommended to maintain phe levels below 360 micromol/L throughout early adolescence...
- Short-term dietary interventions in children and adolescents with treated phenylketonuria: effects on neuropsychological outcome of a well-controlled populationS C J Huijbregts
Department of Clinical Neuropsychology, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands
J Inherit Metab Dis 25:419-30. 2002..The strongest effects were observed when sustained attention and manipulation of working memory content were required. There were some indications of a greater sensitivity of younger patients to fluctuations in Phe concentration...
- The top and the bottom of ADHD: a neuropsychological perspectiveJoseph A Sergeant
Department of Clinical Neuropsychology, Klinische Neuropsychologie, Vrije Universiteit, Van der Boechorststraat 1, 1081 BT Amsterdam, Netherlands
Neurosci Biobehav Rev 27:583-92. 2003..A widely distributed neural network involving frontal, basal ganglia, limbic and cerebellar loci seem implicated in ADHD...