D I Boomsma

Summary

Affiliation: Vrije Universiteit
Country: The Netherlands

Publications

  1. pmc Genome-wide association for major depressive disorder: a possible role for the presynaptic protein piccolo
    P F Sullivan
    Department of Genetics, University of North Carolina, Chapel Hill, NC 27599 7264, USA
    Mol Psychiatry 14:359-75. 2009
  2. ncbi request reprint Using multivariate genetic modeling to detect pleiotropic quantitative trait loci
    D I Boomsma
    Department of Psychonomics, Vrije Universiteit, Amsterdam, The Netherlands
    Behav Genet 26:161-6. 1996
  3. ncbi request reprint Longitudinal stability of the CBCL-juvenile bipolar disorder phenotype: A study in Dutch twins
    Dorret I Boomsma
    Department of Biological Psychology, Vrije Universiteit, Amsterdam, The Netherlands
    Biol Psychiatry 60:912-20. 2006
  4. ncbi request reprint A religious upbringing reduces the influence of genetic factors on disinhibition: evidence for interaction between genotype and environment on personality
    D I Boomsma
    Department of Biological Psychology, Vrije Universiteit, Amsterdam, The Netherlands
    Twin Res 2:115-25. 1999
  5. ncbi request reprint Genetic and environmental contributions to loneliness in adults: the Netherlands twin register study
    Dorret I Boomsma
    Vrije Universiteit, Van der Boechorststraat 1, 1081 Amsterdam, BT, The Netherlands
    Behav Genet 35:745-52. 2005
  6. ncbi request reprint Genetic and environmental influences on Anxious/Depression during childhood: a study from the Netherlands Twin Register
    D I Boomsma
    Department of Biological Psychology, Vrije Universiteit, Van der Boechorststraat 1, 12081 BT Amsterdam, The Netherlands
    Genes Brain Behav 4:466-81. 2005
  7. ncbi request reprint Genetic analysis of indicators of cholesterol synthesis and absorption: lathosterol and phytosterols in Dutch twins and their parents
    Dorret I Boomsma
    Department of Biological Psychology, Vrije Universiteit, The Netherlands
    Twin Res 6:307-14. 2003
  8. ncbi request reprint The effect of apolipoprotein(a)-, apolipoprotein E-, and apolipoprotein A4- polymorphisms on quantitative lipoprotein(a) concentrations
    D I Boomsma
    Vrije Universiteit, Amsterdam, The Netherlands
    Twin Res 3:152-8. 2000
  9. ncbi request reprint Netherlands Twin Register: a focus on longitudinal research
    Dorret I Boomsma
    Department of Biological Psychology, Vrije Universiteit, Amsterdam, The Netherlands
    Twin Res 5:401-6. 2002
  10. ncbi request reprint Twin registers in Europe: an overview
    D I Boomsma
    Department of Psychology, Vrije Universiteit, Amsterdam, The Netherlands
    Twin Res 1:34-51. 1998

Detail Information

Publications106 found, 100 shown here

  1. pmc Genome-wide association for major depressive disorder: a possible role for the presynaptic protein piccolo
    P F Sullivan
    Department of Genetics, University of North Carolina, Chapel Hill, NC 27599 7264, USA
    Mol Psychiatry 14:359-75. 2009
    ..With the integrated replication effort, we present a specific hypothesis for further studies...
  2. ncbi request reprint Using multivariate genetic modeling to detect pleiotropic quantitative trait loci
    D I Boomsma
    Department of Psychonomics, Vrije Universiteit, Amsterdam, The Netherlands
    Behav Genet 26:161-6. 1996
    ..An advantage of this approach is that, rather than employing phenotypic selection, individuals with extreme genotypes may selected when ascertaining a sample of extreme families...
  3. ncbi request reprint Longitudinal stability of the CBCL-juvenile bipolar disorder phenotype: A study in Dutch twins
    Dorret I Boomsma
    Department of Biological Psychology, Vrije Universiteit, Amsterdam, The Netherlands
    Biol Psychiatry 60:912-20. 2006
    ..The purpose of this study is to assess the developmental stability of the CBCL-JBD phenotype across ages 7, 10, and 12 years in a large population-based twin sample and to examine its genetic architecture...
  4. ncbi request reprint A religious upbringing reduces the influence of genetic factors on disinhibition: evidence for interaction between genotype and environment on personality
    D I Boomsma
    Department of Biological Psychology, Vrije Universiteit, Amsterdam, The Netherlands
    Twin Res 2:115-25. 1999
    ..The resemblances between twins for the Disinhibition scale differ according to their religious upbringing. Receiving a religious upbringing seems to reduce the influence of genetic factors on Disinhibition, especially in males...
  5. ncbi request reprint Genetic and environmental contributions to loneliness in adults: the Netherlands twin register study
    Dorret I Boomsma
    Vrije Universiteit, Van der Boechorststraat 1, 1081 Amsterdam, BT, The Netherlands
    Behav Genet 35:745-52. 2005
    ..All resemblance between twin relatives was explained by shared genes, without any suggestion of a contribution of shared environmental factors...
  6. ncbi request reprint Genetic and environmental influences on Anxious/Depression during childhood: a study from the Netherlands Twin Register
    D I Boomsma
    Department of Biological Psychology, Vrije Universiteit, Van der Boechorststraat 1, 12081 BT Amsterdam, The Netherlands
    Genes Brain Behav 4:466-81. 2005
    ..These findings may provide support for why certain family therapeutic approaches are effective in the A/D spectrum of illnesses...
  7. ncbi request reprint Genetic analysis of indicators of cholesterol synthesis and absorption: lathosterol and phytosterols in Dutch twins and their parents
    Dorret I Boomsma
    Department of Biological Psychology, Vrije Universiteit, The Netherlands
    Twin Res 6:307-14. 2003
    ..Taken together, these results confirm and expand the hypothesis that individual differences in plasma levels of noncholesterol sterols are moderately (lathosterol) to highly (plant sterols) heritable...
  8. ncbi request reprint The effect of apolipoprotein(a)-, apolipoprotein E-, and apolipoprotein A4- polymorphisms on quantitative lipoprotein(a) concentrations
    D I Boomsma
    Vrije Universiteit, Amsterdam, The Netherlands
    Twin Res 3:152-8. 2000
    ..A simultaneous analysis of all three loci showed that both the apoE and the apoA4 polymorphism did not contribute significantly to Lp(a) variation...
  9. ncbi request reprint Netherlands Twin Register: a focus on longitudinal research
    Dorret I Boomsma
    Department of Biological Psychology, Vrije Universiteit, Amsterdam, The Netherlands
    Twin Res 5:401-6. 2002
    ..Large cohorts of phenotyped family members from the general population are very valuable for genetic epidemiological studies and permit selection of informative families for gene finding studies...
  10. ncbi request reprint Twin registers in Europe: an overview
    D I Boomsma
    Department of Psychology, Vrije Universiteit, Amsterdam, The Netherlands
    Twin Res 1:34-51. 1998
    ..A short description of 16 registries in nine European countries is presented. These registries have access to over 350000 twin pairs and are a major resource for genetic-epidemiological research...
  11. ncbi request reprint Heritability of blood pressure increases during mental stress
    D I Boomsma
    Department of Physiological Psychology, Vrije Universiteit, Amsterdam, The Netherlands
    Twin Res 1:15-24. 1998
    ..For DBP in males no significant contributions of shared environment were found. The multivariate analyses indicated that the same genetic and environmental influences are expressed during rest and stress conditions...
  12. ncbi request reprint Netherlands Twin Register: from twins to twin families
    Dorret I Boomsma
    Department of Biological Psychology, Vrije Universiteit, Van der Boechorststraat 1, 1081 BT Amsterdam, The Netherlands
    Twin Res Hum Genet 9:849-57. 2006
    ..In this paper we give an update on the YNTR and ANTR phenotyping and on the ongoing ANTR biobank studies...
  13. pmc Genetic epidemiology of attention deficit hyperactivity disorder (ADHD index) in adults
    Dorret I Boomsma
    Department of Biological Psychology, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands
    PLoS ONE 5:e10621. 2010
    ..In contrast to the large number of studies in children, there is little information on the contribution of genetic factors to Attention Deficit Hyperactivity Disorder (ADHD) in adults...
  14. doi request reprint Design and implementation of a twin-family database for behavior genetics and genomics studies
    Dorret I Boomsma
    Biological Psychology, VU University Amsterdam, Amsterdam, The Netherlands
    Twin Res Hum Genet 11:342-8. 2008
    ....
  15. ncbi request reprint Netherlands twin family study of anxious depression (NETSAD)
    D I Boomsma
    Department of Biological Psychology, Vrije Universiteit, Amsterdam, The Netherlands
    Twin Res 3:323-34. 2000
    ..We detail how these data were used to select families for the QTL study and discuss strategies that may help elucidate the molecular pathways leading from genes to anxious depression...
  16. doi request reprint Genome-wide association of major depression: description of samples for the GAIN Major Depressive Disorder Study: NTR and NESDA biobank projects
    Dorret I Boomsma
    Netherlands Twin Register, Department of Biological Psychology, VU University Amsterdam, Amsterdam, Netherlands
    Eur J Hum Genet 16:335-42. 2008
    ..Genome-wide association results are open-access and can be viewed at the dbGAP web portal (http://www.ncbi.nlm.nih.gov). Approved users can download the genotype and phenotype data, which have been made available as of 9 October 2007...
  17. ncbi request reprint A comparison of power to detect a QTL in sib-pair data using multivariate phenotypes, mean phenotypes, and factor scores
    D I Boomsma
    Department of Psychology, Vrije Universiteit, Amsterdam, The Netherlands
    Behav Genet 28:329-40. 1998
    ..The gain in power attributable to the use of factor scores, however, outweighs this observed loss in power. The advantages of using factor scores in selecting sib-pairs are discussed...
  18. pmc Neuroimaging of response interference in twins concordant or discordant for inattention and hyperactivity symptoms
    D van 't Ent
    Department of Biological Psychology, Vrije Universiteit, Amsterdam, The Netherlands
    Neuroscience 164:16-29. 2009
    ....
  19. ncbi request reprint Linkage on chromosome 14 in a genome-wide linkage study of a broad anxiety phenotype
    C M Middeldorp
    Department of Biological Psychology, VU University Amsterdam, Amsterdam, The Netherlands
    Mol Psychiatry 13:84-9. 2008
    ..Two homolog genes lie in this region -Dlk1 (delta-like 1 homolog, Drosophila) and Rtl1 (retrotransposon-like 1). Future association studies of these genes are warranted...
  20. ncbi request reprint Zygosity diagnosis in young twins by parental report
    M J Rietveld
    Vrije Universiteit, Department of Biological Psychology, Amsterdam
    Twin Res 3:134-41. 2000
    ..Analyses of data provided by both parents and collected over multiple ages did not result in better prediction of zygosity. Details on the discriminant function are provided...
  21. ncbi request reprint Genetic and environmental mechanisms underlying stability and change in problem behaviors at ages 3, 7, 10, and 12
    M Bartels
    Department of Biological Psychology, Vrije Universiteit, Amsterdam, Netherlands
    Dev Psychol 40:852-67. 2004
    ..Significant age-specific influences were found for all components, indicating that genetic and environmental factors also contributed to changes in problem behavior...
  22. doi request reprint Life events, anxious depression and personality: a prospective and genetic study
    C M Middeldorp
    Department of Biological Psychology, Vrije Universiteit, Van der Boechorststraat 1, Amsterdam, The Netherlands
    Psychol Med 38:1557-65. 2008
    ..The effect of genes that influence environmental exposure might be mediated through personality and we therefore also examined the association between life events and personality (neuroticism and extraversion)...
  23. doi request reprint Effects of induced hyperinsulinaemia with and without hyperglycaemia on measures of cardiac vagal control
    M Berkelaar
    Diabetes Center, VU University Medical Center, Amsterdam, The Netherlands
    Diabetologia 56:1436-43. 2013
    ..We also examined whether experimentally induced increases in insulin by beta cell secretagogues, including glucagon-like peptide-1 (GLP-1), will decrease vagal control...
  24. pmc Endophenotypes in a dynamically connected brain
    D J A Smit
    Biological Psychology, VU University Amsterdam, Amsterdam, The Netherlands
    Behav Genet 40:167-77. 2010
    ..We conclude that the connectivity parameters SL, CC, and L in the alpha band show the hallmarks of a good endophenotype for behavior and developmental disorders...
  25. ncbi request reprint Twin-singleton differences in intelligence?
    D Posthuma
    Department of Biological Psychology, Vrije Universiteit Amsterdam, The Netherlands
    Twin Res 3:83-7. 2000
    ..It is concluded that twin studies provide reliable estimates of heritabilities of intellectual abilities which can be generalised to the singleton population...
  26. pmc Anxiety and depression in children and adults: influence of serotonergic and neurotrophic genes?
    C M Middeldorp
    Department of Biological Psychology, VU University Amsterdam, Amsterdam, The Netherlands
    Genes Brain Behav 9:808-16. 2010
    ..Overall, there has been no convincing evidence, so far, for a role of genetic variation in these pathways in the development of anxiety and depression...
  27. ncbi request reprint Common variants underlying cognitive ability: further evidence for association between the SNAP-25 gene and cognition using a family-based study in two independent Dutch cohorts
    M F Gosso
    Department of Biological Psychology, Vrije Universiteit, Amsterdam, The Netherlands
    Genes Brain Behav 7:355-64. 2008
    ..As a result, functional polymorphisms in (non)coding regulatory sequences may affect spatial and temporal regulation of gene expression underlying normal cognitive variation...
  28. ncbi request reprint Regular exercise, anxiety, depression and personality: a population-based study
    M H M De Moor
    Department of Biological Psychology, Vrije Universiteit, Van der Boechorststraat 1, 1081 BT, Amsterdam, The Netherlands
    Prev Med 42:273-9. 2006
    ..To examine whether regular exercise is associated with anxiety, depression and personality in a large population-based sample as a function of gender and age...
  29. ncbi request reprint Are smarter brains running faster? Heritability of alpha peak frequency, IQ, and their interrelation
    D Posthuma
    Department of Biological Psychology, Vrije Universiteit, Amsterdam, The Netherlands
    Behav Genet 31:567-79. 2001
    ..There was no evidence of a genetic correlation between alpha peak frequency and any of the four WAIS dimensions: Smarter brains do not seem to run faster...
  30. doi request reprint Life events and borderline personality features: the influence of gene-environment interaction and gene-environment correlation
    M A Distel
    Department of Biological Psychology, VU University Amsterdam, The Netherlands
    Psychol Med 41:849-60. 2011
    ..As the presence of genotype-environment correlation (rGE) can lead to spurious findings of genotype-environment interaction (G × E), we also test whether BPD features increase the likelihood of exposure to life events...
  31. doi request reprint The neural correlates of verbal encoding and retrieval in monozygotic twins at low or high risk for depression and anxiety
    Saskia P A Wolfensberger
    Department of Psychiatry, Vrije Universiteit Medical Center, Amsterdam, The Netherlands
    Biol Psychol 79:80-90. 2008
    ..These results suggest that fMRI activation of the LIFG in a verbal emotional memory task may be a useful vulnerability marker for anxiety and depression...
  32. ncbi request reprint Individual differences in P300 amplitude: a genetic study in adolescent twins
    C E van Beijsterveldt
    Department of Psychophysiology, Vrije Universiteit, Amsterdam, The Netherlands
    Biol Psychol 47:97-120. 1998
    ..Again it was not possible to show that the shared factors where either genetic or shared environmental...
  33. ncbi request reprint The association between exercise participation and well-being: a co-twin study
    J H Stubbe
    Department of Biological Psychology, Vrije Universiteit, Van der Boechorststraat 1, Amsterdam, The Netherlands
    Prev Med 44:148-52. 2007
    ..We investigated the association between leisure time exercise participation and well-being (i.e., life satisfaction and happiness) and examined the causality underlying this association...
  34. ncbi request reprint Genetic analysis of sensation seeking with an extended twin design
    R D Stoel
    Department of Biological Psychology, Vrije Universiteit, Amsterdam, The Netherlands
    Behav Genet 36:229-37. 2006
    ..Evidence for a special twin environment was limited to boredom susceptibility in females...
  35. ncbi request reprint Genetic analyses of maternal and teacher ratings on attention problems in 7-year-old Dutch twins
    E M Derks
    Department Biological Psychology, Vrije Universiteit, Van der Boechorststraat 1, 1081 BT, Amsterdam, The Netherlands
    Behav Genet 36:833-44. 2006
    ..Because Attention Problems that are persistent over situations may indicate more serious behavior problems than context dependent Attention Problems, we believe that gene finding strategies should focus on this common phenotype...
  36. pmc A whole-genome scan for 24-hour respiration rate: a major locus at 10q26 influences respiration during sleep
    E J C de Geus
    Department of Biological Psychology, Vrije Universiteit, Van der Boechorststraat 1, 1081 BT Amsterdam, The Netherlands
    Am J Hum Genet 76:100-11. 2005
    ..Genes in this area (GFRA1, ADORA2L, FGR2, EMX2, and HMX2) can be considered promising positional candidates for genetic association studies of respiratory control during sleep...
  37. ncbi request reprint Association between the CHRM2 gene and intelligence in a sample of 304 Dutch families
    M F Gosso
    Department of Biological Psychology, Vrije Universiteit, Amsterdam, The Netherlands
    Genes Brain Behav 5:577-84. 2006
    ....
  38. ncbi request reprint Heritability of attention problems in children: I. cross-sectional results from a study of twins, age 3-12 years
    M J H Rietveld
    Department of Biological Psychology, Vrije Universiteit, Amsterdam, The Netherlands
    Am J Med Genet B Neuropsychiatr Genet 117:102-13. 2003
    ..The implications of these findings are discussed with reference to the clinical setting and in the context of future research...
  39. ncbi request reprint Co-occurrence of aggressive behavior and rule-breaking behavior at age 12: multi-rater analyses
    M Bartels
    Dept of Psychology, Vrije Universiteit, Amsterdam, The Netherlands
    Behav Genet 33:607-21. 2003
    ..So, co-occurrence in AGG and RB is mainly caused by a common set of genes. Parental disagreement seems to be a combination of so-called rater bias and of parental specific views...
  40. doi request reprint A systematic review of prospective studies on attention problems and academic achievement
    Tinca J C Polderman
    Department of Biological Psychology, VU University Amsterdam, Amsterdam, The Netherlands
    Acta Psychiatr Scand 122:271-84. 2010
    ..Our aim was to provide an overview of prospective studies that have addressed the association between attention problems (AP, i.e. symptoms of hyperactivity and inattentiveness) and academic achievement (AA)...
  41. ncbi request reprint Longitudinal genetic analysis of EEG coherence in young twins
    G C van Baal
    Department of Biological Psychology, Vrije Universiteit, Amsterdam, The Netherlands
    Behav Genet 31:637-51. 2001
    ....
  42. ncbi request reprint The genetic basis of problem behavior in 5-year-old dutch twin pairs
    C E M van Beijsterveldt
    Vrije Universiteit, Amsterdam, The Netherlands
    Behav Genet 34:229-42. 2004
    ..Shared environmental influences were found for aggressive behavior, anxiety problems, dependency, and emotional lability. Rater contrast and/or sibling interaction effects were found for attention problems and physical coordination...
  43. ncbi request reprint Genetic and environmental influences on EEG coherence
    C E van Beijsterveldt
    Department of Psychophysiology, Vrije Universiteit, Amsterdam, The Netherlands
    Behav Genet 28:443-53. 1998
    ..Environmental factors shared by twin siblings did not influence variation in EEG coherence. These results suggest that individual differences in coherence form a potential candidate for (molecular) genetic studies on brain function...
  44. pmc A structural MRI study in monozygotic twins concordant or discordant for attention/hyperactivity problems: evidence for genetic and environmental heterogeneity in the developing brain
    D van 't Ent
    Department of Biological Psychology, Vrije Universiteit, Amsterdam, The Netherlands
    Neuroimage 35:1004-20. 2007
    ..e., high concordant MZ pairs) vs. environmental (i.e., high-low discordant MZ pairs) risk factors. These results provide clues that further our understanding of brain alterations in ADHD...
  45. ncbi request reprint Combined linkage and association tests in mx
    D Posthuma
    Department of Biological Psychology, Vrije Universiteit Amsterdam, Van der Boechorststraat 1, 1081 BT The Netherlands
    Behav Genet 34:179-96. 2004
    ..These extensions can be implemented when parental genotypes are available or unavailable...
  46. ncbi request reprint Exercise participation and self-rated health: do common genes explain the association?
    M H M De Moor
    Department of Biological Psychology, Vrije Universiteit, Van der Boechorststraat 1, 1081 BT Amsterdam, The Netherlands
    Eur J Epidemiol 22:27-32. 2007
    ..We propose that identification of the genes that cause differences in exercise behavior will help resolve the issue of causality...
  47. doi request reprint Gamma frailty model for linkage analysis with application to interval-censored migraine data
    M A Jonker
    Department of Mathematics, Faculty of Sciences, Vrije Universiteit, De Boelelaan 1081 a, 1081 HV Amsterdam, The Netherlands
    Biostatistics 10:187-200. 2009
    ..Heritability (obtained from the frailties rather than actual onset times) was estimated as 0.42; this value was highly significant. The highest lod score, a score of 1.9, was found at the end of chromosome 19...
  48. pmc The heritability of beta cell function parameters in a mixed meal test design
    A M C Simonis-Bik
    Diabetes Center, VU University Medical Center, ZH 4A62, PO Box 7057, 1007 MB, Amsterdam, The Netherlands
    Diabetologia 54:1043-51. 2011
    ..We estimated the heritability of individual differences in beta cell function after a mixed meal test designed to assess a wide range of classical and model-derived beta cell function parameters...
  49. doi request reprint Genetic influences on 'environmental' factors
    A A E Vinkhuyzen
    Department of Biological Psychology, VU University Amsterdam, The Netherlands
    Genes Brain Behav 9:276-87. 2010
    ..Understanding causes of individual differences in external factors may aid in clarifying the intricate nature between genetic and environmental influences on complex traits...
  50. pmc The genetic association between personality and major depression or bipolar disorder. A polygenic score analysis using genome-wide association data
    C M Middeldorp
    Department of Biological Psychology, VU University Amsterdam, Amsterdam, The Netherlands
    Transl Psychiatry 1:e50. 2011
    ..This study suggests shared genetic risk factors for neuroticism and MDD on the one hand and for extraversion and BD on the other...
  51. ncbi request reprint Genetic analysis of morningness and eveningness
    J M Vink
    Department of Biological Psychology, Free University of Amsterdam, The Netherlands
    Chronobiol Int 18:809-22. 2001
    ..However, the genetic correlation between the generations turned out to be lower than 0.5, suggesting that different genes for morningness-eveningness are expressed in both generations...
  52. ncbi request reprint The influence of religion on alcohol use initiation: evidence for genotype X environment interaction
    J R Koopmans
    Free University, Amsterdam, The Netherlands
    Behav Genet 29:445-53. 1999
    ..Whether or not they were raised religiously, the liability to alcohol use initiation in males was moderately influenced by genetic factors (30%) and substantially influenced by shared environmental factors (60%)...
  53. ncbi request reprint Stability of genetic and environmental influences on P300 amplitude: a longitudinal study in adolescent twins
    C E van Beijsterveldt
    Vrije Universiteit, Department Biological Psychology, Amsterdam, The Netherlands
    Behav Genet 31:533-43. 2001
    ..The phenotypic stability of the P300 amplitude from 16 to 18 years was high in both sexes, and stability could be attributed largely to the same familial factors. There was no evidence that new familial influences emerged at age 18...
  54. ncbi request reprint Mx scripts library: structural equation modeling scripts for twin and family data
    D Posthuma
    Department of Biological Psychology, Vrije Universiteit, Van der Boechorststraat 1, 1081, BT, Amsterdam, The Netherlands
    Behav Genet 35:499-505. 2005
    ..The scripts are written to be used with the freely available software package Mx and provide a flexible and uniform approach to the analysis of data from relatives...
  55. doi request reprint A frailty model for (interval) censored family survival data, applied to the age at onset of non-physical problems
    M A Jonker
    Department of Mathematics, Faculty of Sciences, VU University Amsterdam, 1081 HV, Amsterdam, The Netherlands
    Lifetime Data Anal 16:299-315. 2010
    ....
  56. ncbi request reprint Genetic influences on disordered eating behaviour are largely independent of body mass index
    M C T Slof-Op 't Landt
    Center for Eating Disorders Ursula, Leidschendam, Amsterdam, The Netherlands
    Acta Psychiatr Scand 117:348-56. 2008
    ..We are interested in identifying the genes underlying disordered eating behaviour (DEB), and want to know how much of the genetic influence underlying DEB is attributable to genetic influences on body mass index (BMI)...
  57. ncbi request reprint A note on the statistical power in extended twin designs
    D Posthuma
    Department of Biological Psychology, Vrije Universiteit Amsterdam, Netherlands
    Behav Genet 30:147-58. 2000
    ..e. including families with twins and one or two additional siblings increases the statistical power to detect sources of variance due to additive and non-additive genetic influences, and common environment...
  58. ncbi request reprint Genetic influences on EEG coherence in 5-year-old twins
    G C van Baal
    Department of Psychophysiology, Vrije Universiteit, Amsterdam, The Netherlands
    Behav Genet 28:9-19. 1998
    ....
  59. ncbi request reprint Using shared and unique parental views to study the etiology of 7-year-old twins' internalizing and externalizing problems
    J C van der Valk
    Department of Biological Psychology, Vrije Universiteit, Van der Boechorststraat 1, 1081 BT Amsterdam, The Netherlands
    Behav Genet 33:409-20. 2003
    ..For both Externalizing and Internalizing problems, around 30% of the variance was accounted for by the shared environmental factors...
  60. ncbi request reprint Heritability of life satisfaction in adults: a twin-family study
    J H Stubbe
    Department of Biological Psychology, Vrije Universiteit Amsterdam, Van der Boechorststraat 1, 1081 BT Amsterdam, The Netherlands
    Psychol Med 35:1581-8. 2005
    ..The aim of this study was to investigate the relative contribution of genes and environment to individual differences in life satisfaction in a large sample of Dutch twins and their singleton siblings...
  61. ncbi request reprint Genetic mediation of the correlation between peripheral nerve conduction velocity and IQ
    F V Rijsdijk
    Department of Psychonomics, Vrije Universiteit, Amsterdam, The Netherlands
    Behav Genet 27:87-98. 1997
    ..This is in line with the suggestion of increasing heritability of IQ in adulthood...
  62. ncbi request reprint Linkage analysis of smoking initiation and quantity in Dutch sibling pairs
    J M Vink
    Department of Biological Psychology, Vrije Universiteit, Amsterdam, The Netherlands
    Pharmacogenomics J 4:274-82. 2004
    ..66) for SI and on chromosome 3 (LOD=1.98) for NC. Strikingly, on chromosome 10 a peak was found in the same region for both SI (LOD=1.92) and for NC (LOD=2.29) which may partly explain the overlapping etiological factors for SI and NC...
  63. ncbi request reprint Optimal selection of sib pairs from random samples for linkage analysis of a QTL using the EDAC test
    C V Dolan
    Department of Psychology, Vrije Universiteit, Amsterdam, The Netherlands
    Behav Genet 28:197-206. 1998
    ..The soundness of these recommendations is subsequently in a number of test cases...
  64. pmc Meta-analysis of genome-wide association studies for personality
    M H M De Moor
    Department of Biological Psychology, VU University Amsterdam, Amsterdam, The Netherlands
    Mol Psychiatry 17:337-49. 2012
    ..Larger scale GWA studies and alternative approaches are required for confirmation of KATNAL2 as a novel gene affecting Conscientiousness...
  65. ncbi request reprint Bivariate genetic analysis of fasting insulin and glucose levels
    H Snieder
    Department of Psychophysiology, Vrije Universiteit, Amsterdam, The Netherlands
    Genet Epidemiol 16:426-46. 1999
    ....
  66. ncbi request reprint The SNAP-25 gene is associated with cognitive ability: evidence from a family-based study in two independent Dutch cohorts
    M F Gosso
    Department of Biological Psychology, Vrije Universiteit, Amsterdam, The Netherlands
    Mol Psychiatry 11:878-86. 2006
    ..84 PIQ points (P=0.0002). Variance in this SNP accounts for 3.4% of the phenotypic variance in PIQ...
  67. ncbi request reprint Causes of stability of aggression from early childhood to adolescence: a longitudinal genetic analysis in Dutch twins
    C E M van Beijsterveldt
    Department of Biological Psychology, Vrije Universiteit, Amsterdam, The Netherlands
    Behav Genet 33:591-605. 2003
    ..These data support the idea that both genetic and environmental influences play a role in the stability of AGG from age 3 to 12...
  68. ncbi request reprint The genetic basis of the relation between speed-of-information-processing and IQ
    F V Rijsdijk
    Department of Psychonomics, Vrije Universiteit, Amsterdam, The Netherlands
    Behav Brain Res 95:77-84. 1998
    ..These results are in agreement with earlier findings (Baker et al., Behav Genet 1991;21:351-67; Ho et al., Behav Genet 1988;18:247-61) and support the existence of a common, heritable biological basis underlying the SIP-IQ relationship...
  69. ncbi request reprint Frequency of parental report of problem behavior in children decreases with increasing maternal age at delivery
    J F Orlebeke
    Department of Physiological Psychology, Vrije Universiteit, Amsterdam, The Netherlands
    Psychol Rep 82:395-404. 1998
    ..This was true for both boys and girls as well as for first and secondborn twins. Evidence in support of a biological explanation of the association between maternal age and child behavior problems, is presented...
  70. doi request reprint Marital resemblance for obsessive-compulsive, anxious and depressive symptoms in a population-based sample
    D S van Grootheest
    Department of Biological Psychology, VU University, Amsterdam, The Netherlands
    Psychol Med 38:1731-40. 2008
    ..We examined the existence and cause(s) of assortment for obsessive-compulsive (OC), anxious and depressive symptoms in a population-based twin-family sample...
  71. ncbi request reprint Etiology of individual differences in birth weight of twins as a function of maternal smoking during pregnancy
    C G van Baal
    Vrije Universiteit, Amsterdam, The Netherlands
    Twin Res 1:123-30. 1998
    ..Common environmental influences other than gestational age accounted for a slightly larger part of the variance not associated with gestational age (17-20%)...
  72. ncbi request reprint Genetics of parentally reported asthma, eczema and rhinitis in 5-yr-old twins
    C E M van Beijsterveldt
    Dept of Biological Psychology, Vrije Universiteit, Van der Boechorststraat 1, 1081 BT Amsterdam, The Netherlands
    Eur Respir J 29:516-21. 2007
    ..The high heritability and the limited influence of shared environmental factors may point to gene x environment interactions. Future research should focus on this type of interaction processes...
  73. ncbi request reprint The relation between frontal EEG asymmetry and the risk for anxiety and depression
    D J A Smit
    Department of Biological Psychology, Vrije Universiteit of Amsterdam, Van der Boechorststraat 1, 1081 BT Amsterdam, The Netherlands
    Biol Psychol 74:26-33. 2007
    ..This relation was explained by shared genes influencing both EEG and disease risk. Future studies on asymmetry of left and right frontal brain activation should carefully consider the effects of sex and age...
  74. ncbi request reprint Heritability of background EEG across the power spectrum
    D J A Smit
    Department of Biological Psychology, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands
    Psychophysiology 42:691-7. 2005
    ..We conclude that across the scalp and most of the frequency spectrum, individual differences in adult EEG are largely determined by genetic factors...
  75. ncbi request reprint A study of genetic and environmental influences on maternal and paternal CBCL syndrome scores in a large sample of 3-year-old Dutch twins
    E M Derks
    Department of Biological Psychology, Vrije Universiteit, Amsterdam, The Netherlands
    Behav Genet 34:571-83. 2004
    ....
  76. ncbi request reprint Genetic factor analyses of specific cognitive abilities in 5-year-old Dutch children
    M J Rietveld
    Department of Biological Psychology, Vrije Universiteit, Amsterdam, The Netherlands
    Behav Genet 30:29-40. 2000
    ..The phenotypic data was best described by an oblique two-factor model. This model was not mirrored in the factor structures found for either the genetic or environmental covariances...
  77. ncbi request reprint Heritability of attention problems in children: longitudinal results from a study of twins, age 3 to 12
    M J H Rietveld
    Department of Biological Psychology, Vrije Universiteit, Amsterdam, The Netherlands
    J Child Psychol Psychiatry 45:577-88. 2004
    ..In the present longitudinal twin study, we report on the size of genetic and environmental effects on individual differences in attention problems at ages 3, 7, 10 and 12 years...
  78. ncbi request reprint A twin study of differentiation of cognitive abilities in childhood
    M J H Rietveld
    Department of Biological Psychology, Vrije Universiteit, Van der Boechorststraat 1, 1081 BT Amsterdam, The Netherlands
    Behav Genet 33:367-81. 2003
    ..Stability in subtest performance is due mainly to genetic influences. The shared environment contribution to phenotypic stability is small. The unique environment contributes to age-specific variance only...
  79. ncbi request reprint Genetics of testosterone and the aggression-hostility-anger (AHA) syndrome: a study of middle-aged male twins
    F Sluyter
    Department of Psychoneuropharmacology, University of Nijmegen, The Netherlands
    Twin Res 3:266-76. 2000
    ....
  80. ncbi request reprint Heritability of cortisol levels: review and simultaneous analysis of twin studies
    M Bartels
    Department of Biological Psychology, Vrije Universiteit, Amsterdam, The Netherlands
    Psychoneuroendocrinology 28:121-37. 2003
    ....
  81. ncbi request reprint Gene finding strategies
    Jacqueline M Vink
    Department of Biological Psychology, Free University of Amsterdam, Van der Boechorstraat 1, 1081 BT Amsterdam, The Netherlands
    Biol Psychol 61:53-71. 2002
    ..Allelic association between a trait and a marker can be studied in a case-control design, but because of possible problems due to population stratification, within-family designs have been proposed as the optimal test for association...
  82. ncbi request reprint Genetic and environmental influences on the development of intelligence
    M Bartels
    Department of Biological Psychology, Vrije Universiteit, Amsterdam, The Netherlands
    Behav Genet 32:237-49. 2002
    ..Shared environmental influences are responsible for stability as well as change in the development of cognitive abilities, represented by a common factor influencing FSIQ at all ages and age-specific influences, respectively...
  83. ncbi request reprint Familial clustering in burnout: a twin-family study
    C M Middeldorp
    Department of Biological Psychology, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands
    Psychol Med 35:113-20. 2005
    ..Finally, we tried to identify specific risk factors for burnout...
  84. ncbi request reprint The co-morbidity of anxiety and depression in the perspective of genetic epidemiology. A review of twin and family studies
    C M Middeldorp
    Department of Biological Psychology, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands
    Psychol Med 35:611-24. 2005
    ..The aim of this paper is to evaluate the theory of Gray and McNaughton using the results of genetic epidemiological studies...
  85. ncbi request reprint Introduction to the special issue: human linkage studies for behavioral traits
    D Posthuma
    Department of Biological Psychology, Vrije Universiteit, Amsterdam, The Netherlands
    Behav Genet 36:1-3. 2006
    ..Three papers concentrate on emotionality, depression and loneliness and examine chromosomes 2q and 12q. The papers in this issue represent a summary of the first large scale linkage enterprises of human behavioral traits...
  86. ncbi request reprint A note on the power provided by sibships of sizes 2, 3, and 4 in genetic covariance modeling of a codominant QTL
    C V Dolan
    Department of Psychology, University of Amsterdam, The Netherlands
    Behav Genet 29:163-70. 1999
    ..Three of the 10 size 3 and 7 of the 36 size 4 sibships are particularly informative. The results presented concern random (unselective) sampling but do have implications for selective sampling...
  87. ncbi request reprint Heritability of polycystic ovary syndrome in a Dutch twin-family study
    J M Vink
    Department of Biological Psychology, Vrije Universiteit, Van de Boechorststraat 1, 1081 BT Amsterdam, The Netherlands
    J Clin Endocrinol Metab 91:2100-4. 2006
    ..Polycystic ovary syndrome (PCOS) is one of the most common endocrine disorders among women of reproductive age. There is evidence for a genetic component in PCOS based on familial clustering of cases...
  88. doi request reprint No effect of classroom sharing on educational achievement in twins: a prospective, longitudinal cohort study
    T J C Polderman
    Department of Biological Psychology, VU University Amsterdam, Van der Boechorststraat 1, 1081 BT, Amsterdam, The Netherlands
    J Epidemiol Community Health 64:36-40. 2010
    ..This study investigated the effects of sharing a classroom during primary school on cognitive achievement in twins...
  89. ncbi request reprint Genetic analysis of IQ, processing speed and stimulus-response incongruency effects
    D Posthuma
    Department of Biological Psychology, Vrije Universiteit Amsterdam, Van der Boechorststraat 1, 1081 BT Amsterdam, The Netherlands
    Biol Psychol 61:157-82. 2002
    ..It is concluded that measures of the ability to perform well under conditions of stimulus-response incongruency are viable endophenotypes of cognitive ability...
  90. ncbi request reprint Evidence for genetic factors explaining the association between birth weight and low-density lipoprotein cholesterol and possible intrauterine factors influencing the association between birth weight and high-density lipoprotein cholesterol: analysis in t
    R G Ijzerman
    Department of Internal Medicine and Institute for Cardiovascular Research-Vrije Universiteit, Academic Hospital Vrije Universiteit, Amsterdam, The Netherlands
    J Clin Endocrinol Metab 86:5479-84. 2001
    ....
  91. ncbi request reprint Asthma genetics and intermediate phenotypes: a review from twin studies
    H Los
    Department of Pulmonary Medicine, Refaja Hospital, Stadskanaal, The Netherlands
    Twin Res 4:81-93. 2001
    ....
  92. ncbi request reprint Quantitative genetic modeling of variation in human brain morphology
    W F Baaré
    Department of Psychiatry, University Medical Center Utrecht, The Netherlands
    Cereb Cortex 11:816-24. 2001
    ..The high heritability estimates that were found indicate that brain volumes may be useful as intermediate phenotypes in behavioral genetic research...
  93. ncbi request reprint A powerful and rapid approach to human genome scanning using small quantities of genomic DNA
    M Beekman
    Gaubius Laboratory, TNO Prevention and Health, PO Box 2215, 2301 CE Leiden, The Netherlands
    Genet Res 77:129-34. 2001
    ..A genome scan following this modified protocol can be performed using a maximum amount of 2.5 micrograms of genomic DNA per individual, isolated from either blood or from mouth swabs...
  94. ncbi request reprint Genetic contributions to the association between height and intelligence: Evidence from Dutch twin data from childhood to middle age
    K Silventoinen
    Department of Public Health, University of Helsinki, Helsinki, Finland
    Genes Brain Behav 5:585-95. 2006
    ....
  95. ncbi request reprint ADHD: sibling interaction or dominance: an evaluation of statistical power
    M J H Rietveld
    Department of Biological Psychology, Vrije Universiteit, Amsterdam, The Netherlands
    Behav Genet 33:247-55. 2003
    ....
  96. ncbi request reprint Individual differences in aggression: genetic analyses by age, gender, and informant in 3-, 7-, and 10-year-old Dutch twins
    J J Hudziak
    Departments of Psychiatry and Medicine, Division of Human Genetics, Center for Children Youth and Families, University of Vermont, College of Medicine, Burlington Vermont 05405, USA
    Behav Genet 33:575-89. 2003
    ..Contributions of common (13%-27%) and unique (16%-31%) environment were small to moderate. There was some evidence of genetic dominance by teacher report for 10-year-old girls...
  97. ncbi request reprint [Growth charts for height, weight and body-mass index of twins during infancy]
    P Van Dommelen
    Faculteit Exacte Wetenschappen, afd Wiskunde, Vrije Universiteit, Amsterdam
    Ned Tijdschr Geneeskd 148:1345-50. 2004
    ....
  98. ncbi request reprint Genetic time-series analysis identifies a major QTL for in vivo alcohol metabolism not predicted by in vitro studies of structural protein polymorphism at the ADH1B or ADH1C loci
    A J Birley
    Queensland Institute of Medical Research and Joint Genetics Program, University of Queensland, 300 Herston Road, Herston, Brisbane, QLD, 4029, Australia
    Behav Genet 35:509-24. 2005
    ..Earlier analyses of these data suggested that alcohol metabolism is related to drinking behavior and imply that this QTL may be protective against alcohol dependence...
  99. ncbi request reprint Heritability of borderline personality disorder features is similar across three countries
    M A Distel
    Department of Biological Psychology, VU University, Amsterdam, The Netherlands
    Psychol Med 38:1219-29. 2008
    ..Though family history studies of borderline personality disorder indicate genetic influences, there have been very few twin studies and the degree of genetic influence on borderline personality disorder remains unclear...
  100. ncbi request reprint Heritability of anterior and posterior visual N1
    D J A Smit
    Department of Biological Psychology, Vrije Universiteit Amsterdam, The Netherlands
    Int J Psychophysiol 66:196-204. 2007
    ..We conclude that visual N1 amplitude and latency may serve as endophenotypes to detect genetic variation in susceptibility to psychiatric disorders...
  101. ncbi request reprint A whole genome association study of neuroticism using DNA pooling
    S Shifman
    Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK
    Mol Psychiatry 13:302-12. 2008
    ..Our findings argue the need for much larger samples than anticipated in genetic association studies and that the biological basis of emotional disorders is extremely complex...