R Zeller

Summary

Affiliation: Utrecht University
Country: The Netherlands

Publications

  1. ncbi Formin defines a large family of morphoregulatory genes and functions in establishment of the polarising region
    R Zeller
    European Molecular Biology Laboratory, Meyerhofstrasse 1, D 69117 Heidelberg, Germany
    Cell Tissue Res 296:85-93. 1999
  2. ncbi Gli3 (Xt) and formin (ld) participate in the positioning of the polarising region and control of posterior limb-bud identity
    A Zuniga
    EMBL, Meyerhofstrasse 1, D 69117 Heidelberg, Germany
    Development 126:13-21. 1999
  3. ncbi Dorso-ventral limb polarity and origin of the ridge: on the fringe of independence?
    R Zeller
    European Molecular Biology Laboratory, Heidelberg, Germany
    Bioessays 19:541-6. 1997
  4. ncbi Molecular interaction between limb deformity proteins (formins) and Src family kinases
    P Uetz
    EMBL, Meyerhofstrasse 1, 69117 Heidelberg, Germany
    J Biol Chem 271:33525-30. 1996
  5. ncbi AltFGF-2, a novel ER-associated FGF-2 protein isoform: its embryonic distribution and functional analysis during neural tube development
    A Zúñiga Mejía Borja
    EMBL, Meyerhofstrasse 1, Heidelberg, D 69117, Germany
    Dev Biol 180:680-92. 1996
  6. ncbi Signal relay by BMP antagonism controls the SHH/FGF4 feedback loop in vertebrate limb buds
    A Zuniga
    Department of Developmental Biology, Faculty of Biology, Utrecht University, The Netherlands
    Nature 401:598-602. 1999
  7. ncbi The chicken limb deformity gene encodes nuclear proteins expressed in specific cell types during morphogenesis
    A Trumpp
    EMBL Differentiation Programme, Heidelberg, Germany
    Genes Dev 6:14-28. 1992
  8. ncbi The limb deformity mutation disrupts the SHH/FGF-4 feedback loop and regulation of 5' HoxD genes during limb pattern formation
    A G Haramis
    EMBL, Heidelberg, Germany
    Development 121:4237-45. 1995
  9. ncbi Disruption of formin-encoding transcripts in two mutant limb deformity alleles
    R L Mass
    Department of Genetics, Harvard Medical School, Boston, Massachusetts
    Nature 346:853-5. 1990
  10. ncbi 'Formins': proteins deduced from the alternative transcripts of the limb deformity gene
    R P Woychik
    Department of Genetics, Harvard Medical School, Boston, Massachusetts
    Nature 346:850-3. 1990

Collaborators

  • D James
  • EDWARD DE ROBERTIS
  • D Duboule
  • A Zuniga
  • G Davidson
  • P Uetz
  • A Zúñiga Mejía Borja
  • R Dono
  • A G Haramis
  • A P McMahon
  • A P Haramis
  • C Murphy
  • S Fumagalli
  • J M Brown
  • A Trumpp
  • R P Woychik
  • J L de la Pompa
  • P Leder
  • T R Burglin
  • T F Vogt
  • R L Mass
  • P A Blundell
  • I W Mattaj
  • D D Newmeyer
  • R L Maas

Detail Information

Publications13

  1. ncbi Formin defines a large family of morphoregulatory genes and functions in establishment of the polarising region
    R Zeller
    European Molecular Biology Laboratory, Meyerhofstrasse 1, D 69117 Heidelberg, Germany
    Cell Tissue Res 296:85-93. 1999
    ....
  2. ncbi Gli3 (Xt) and formin (ld) participate in the positioning of the polarising region and control of posterior limb-bud identity
    A Zuniga
    EMBL, Meyerhofstrasse 1, D 69117 Heidelberg, Germany
    Development 126:13-21. 1999
    ..Concurrently, Gli3 functions independently of formin during initial posterior nesting of 5'HoxD domains, whereas their subsequent distal restriction and anterior expansion depends on genetic interaction of Gli3 and formin...
  3. ncbi Dorso-ventral limb polarity and origin of the ridge: on the fringe of independence?
    R Zeller
    European Molecular Biology Laboratory, Heidelberg, Germany
    Bioessays 19:541-6. 1997
    ....
  4. ncbi Molecular interaction between limb deformity proteins (formins) and Src family kinases
    P Uetz
    EMBL, Meyerhofstrasse 1, 69117 Heidelberg, Germany
    J Biol Chem 271:33525-30. 1996
    ..These studies indicate that the morphoregulatory Ld proteins interact with signal transduction cascades by association to membrane-bound Src family kinases...
  5. ncbi AltFGF-2, a novel ER-associated FGF-2 protein isoform: its embryonic distribution and functional analysis during neural tube development
    A Zúñiga Mejía Borja
    EMBL, Meyerhofstrasse 1, Heidelberg, D 69117, Germany
    Dev Biol 180:680-92. 1996
    ....
  6. ncbi Signal relay by BMP antagonism controls the SHH/FGF4 feedback loop in vertebrate limb buds
    A Zuniga
    Department of Developmental Biology, Faculty of Biology, Utrecht University, The Netherlands
    Nature 401:598-602. 1999
    ....
  7. ncbi The chicken limb deformity gene encodes nuclear proteins expressed in specific cell types during morphogenesis
    A Trumpp
    EMBL Differentiation Programme, Heidelberg, Germany
    Genes Dev 6:14-28. 1992
    ..Unexpected expression in the notochord, floor plate, and ventral horns suggests an involvement of the ld gene products in establishment of the dorsoventral polarity of the neural tube...
  8. ncbi The limb deformity mutation disrupts the SHH/FGF-4 feedback loop and regulation of 5' HoxD genes during limb pattern formation
    A G Haramis
    EMBL, Heidelberg, Germany
    Development 121:4237-45. 1995
    ..These studies show that the AER defect in ld homozygous limb buds causes disruption of the FGF-4/SHH feedback loop and support the proposed essential role for FGF-4 in maintaining Shh expression during limb pattern formation...
  9. ncbi Disruption of formin-encoding transcripts in two mutant limb deformity alleles
    R L Mass
    Department of Genetics, Harvard Medical School, Boston, Massachusetts
    Nature 346:853-5. 1990
    ..That the defect is limited to the limb and kidney, despite expression of ld mRNA in other unaffected organs, suggests that these mutant alleles represent only partial loss of ld function...
  10. ncbi 'Formins': proteins deduced from the alternative transcripts of the limb deformity gene
    R P Woychik
    Department of Genetics, Harvard Medical School, Boston, Massachusetts
    Nature 346:850-3. 1990
    ..The observation of these different RNA transcripts in different tissues suggests that the formins play a part in the formation of several organ systems...
  11. ncbi Cloning of nucleoplasmin from Xenopus laevis oocytes and analysis of its developmental expression
    T R Burglin
    Biocenter of the University of Basel, Switzerland
    Genes Dev 1:97-107. 1987
    ..These results support the notion that nucleoplasmin is not only important in oocytes but also plays a major role during the rapid cleavages of early embryogenesis...
  12. ncbi The limb deformity gene is required for apical ectodermal ridge differentiation and anteroposterior limb pattern formation
    R Zeller
    Department of Genetics, Harvard Medical School, Howard Hughes Medical Institute, Boston, Massachusetts 02115
    Genes Dev 3:1481-92. 1989
    ..These data lead us to conclude that ld gene products are required for both proper AER differentiation and anteroposterior pattern formation in limb mesenchyme...
  13. ncbi FGF signalling is required for differentiation-induced cytoskeletal reorganisation and formation of actin-based processes by podocytes
    G Davidson
    EMBL, Meyerhofstrasse1, D-69117 Heidelberg, Germany
    J Cell Sci 114:3359-66. 2001
    ..Together with other studies, these results point to a general role for FGF signalling in regulating cell differentiation and formation of actin-based cellular processes during morphogenesis...