Dick J Van der Horst

Summary

Affiliation: Utrecht University
Country: The Netherlands

Publications

  1. ncbi request reprint Alternative lipid mobilization: the insect shuttle system
    Dick J Van der Horst
    Department of Biochemical Physiology and Institute of Biomembranes, Utrecht University, Utrecht, The Netherlands
    Mol Cell Biochem 239:113-9. 2002
  2. ncbi request reprint Insect adipokinetic hormones: release and integration of flight energy metabolism
    Dick J Van der Horst
    Department of Biochemical Physiology and Institute of Biomembranes, Utrecht University, Padualaan 8, Utrecht 3584 CH, The Netherlands
    Comp Biochem Physiol B Biochem Mol Biol 136:217-26. 2003
  3. doi request reprint The complex of the insect LDL receptor homolog, lipophorin receptor, LpR, and its lipoprotein ligand does not dissociate under endosomal conditions
    Sigrid D Roosendaal
    Division of Endocrinology and Metabolism, Department of Biology, Institute of Biomembranes, Utrecht University, Utrecht, The Netherlands
    FEBS J 275:1751-66. 2008
  4. doi request reprint Delipidation of insect lipoprotein, lipophorin, affects its binding to the lipophorin receptor, LpR: implications for the role of LpR-mediated endocytosis
    Sigrid D Roosendaal
    Division of Endocrinology and Metabolism, Department of Biology and Institute of Biomembranes, Utrecht University, Padualaan 8, 3584 CH Utrecht, The Netherlands
    Insect Biochem Mol Biol 39:135-44. 2009
  5. doi request reprint Effects of AMPK activators on the sub-cellular distribution of fatty acid transporters CD36 and FABPpm
    Masja M van Oort
    Division of Endocrinology and Metabolism, Department of Biology and Institute of Biomembranes, Utrecht University, NL 3584 CH Utrecht, The Netherlands
    Arch Physiol Biochem 115:137-46. 2009
  6. ncbi request reprint Intracellular fate of LDL receptor family members depends on the cooperation between their ligand-binding and EGF domains
    Dennis Van Hoof
    Department of Biochemical Physiology and Institute of Biomembranes, Utrecht University, Padualaan 8, 3584 CH Utrecht, The Netherlands
    J Cell Sci 118:1309-20. 2005
  7. ncbi request reprint Receptor-mediated endocytosis and intracellular trafficking of lipoproteins and transferrin in insect cells
    Dennis Van Hoof
    Department of Biochemical Physiology and Institute of Biomembranes, Utrecht University, Padualaan 8, Room W 209, Utrecht 3584 CH, The Netherlands
    Insect Biochem Mol Biol 35:117-28. 2005
  8. ncbi request reprint Insect lipoprotein biogenesis depends on an amphipathic beta cluster in apolipophorin II/I and is stimulated by microsomal triglyceride transfer protein
    Marcel M W Smolenaars
    Division of Endocrinology and Metabolism, Department of Biology and Institute of Biomembranes, Utrecht University, Utrecht, The Netherlands
    J Lipid Res 48:1955-65. 2007
  9. doi request reprint Circulatory lipid transport: lipoprotein assembly and function from an evolutionary perspective
    Dick J Van der Horst
    Division of Endocrinology and Metabolism, Department of Biology and Institute of Biomembranes, Utrecht University, Padualaan 8, 3584 CH, Utrecht, The Netherlands
    Mol Cell Biochem 326:105-19. 2009
  10. ncbi request reprint Lipophorin receptor-mediated lipoprotein endocytosis in insect fat body cells
    Dennis Van Hoof
    Department of Biochemical Physiology and Institute of Biomembranes, Utrecht University, Padualaan 8, 3584 CH Utrecht, The Netherlands
    J Lipid Res 44:1431-40. 2003

Collaborators

Detail Information

Publications19

  1. ncbi request reprint Alternative lipid mobilization: the insect shuttle system
    Dick J Van der Horst
    Department of Biochemical Physiology and Institute of Biomembranes, Utrecht University, Utrecht, The Netherlands
    Mol Cell Biochem 239:113-9. 2002
    ..On the other hand, the deviant behavior of similar molecules in a different biological system may provide a useful alternative model for studying the molecular basis of processes related to human disorders and disease...
  2. ncbi request reprint Insect adipokinetic hormones: release and integration of flight energy metabolism
    Dick J Van der Horst
    Department of Biochemical Physiology and Institute of Biomembranes, Utrecht University, Padualaan 8, Utrecht 3584 CH, The Netherlands
    Comp Biochem Physiol B Biochem Mol Biol 136:217-26. 2003
    ..Many structural elements of the lipoprotein system of insects appear to be similar to their counterparts in mammals; however, the functioning of the insect lipoprotein in energy transport during flight activity is intriguingly different...
  3. doi request reprint The complex of the insect LDL receptor homolog, lipophorin receptor, LpR, and its lipoprotein ligand does not dissociate under endosomal conditions
    Sigrid D Roosendaal
    Division of Endocrinology and Metabolism, Department of Biology, Institute of Biomembranes, Utrecht University, Utrecht, The Netherlands
    FEBS J 275:1751-66. 2008
    ..Together, these data indicate that LpR and HDLp travel in complex to the endocytic recycling compartment, which constitutes a key determinant for ligand recycling by LpR...
  4. doi request reprint Delipidation of insect lipoprotein, lipophorin, affects its binding to the lipophorin receptor, LpR: implications for the role of LpR-mediated endocytosis
    Sigrid D Roosendaal
    Division of Endocrinology and Metabolism, Department of Biology and Institute of Biomembranes, Utrecht University, Padualaan 8, 3584 CH Utrecht, The Netherlands
    Insect Biochem Mol Biol 39:135-44. 2009
    ....
  5. doi request reprint Effects of AMPK activators on the sub-cellular distribution of fatty acid transporters CD36 and FABPpm
    Masja M van Oort
    Division of Endocrinology and Metabolism, Department of Biology and Institute of Biomembranes, Utrecht University, NL 3584 CH Utrecht, The Netherlands
    Arch Physiol Biochem 115:137-46. 2009
    ..Thus, for the first time in intact cells, we present evidence for AMPK-mediated translocation of CD36 from intracellular pools to the PM, similar to GLUT4, whereas FABPpm is not relocated...
  6. ncbi request reprint Intracellular fate of LDL receptor family members depends on the cooperation between their ligand-binding and EGF domains
    Dennis Van Hoof
    Department of Biochemical Physiology and Institute of Biomembranes, Utrecht University, Padualaan 8, 3584 CH Utrecht, The Netherlands
    J Cell Sci 118:1309-20. 2005
    ..The LDLR mutant characterization in vitro suggests that LDLR FH class 5 mutations might be divided into two subclasses...
  7. ncbi request reprint Receptor-mediated endocytosis and intracellular trafficking of lipoproteins and transferrin in insect cells
    Dennis Van Hoof
    Department of Biochemical Physiology and Institute of Biomembranes, Utrecht University, Padualaan 8, Room W 209, Utrecht 3584 CH, The Netherlands
    Insect Biochem Mol Biol 35:117-28. 2005
    ..A chase following endocytosis of labeled lipophorin by isolated fat body tissue at this developmental stage resulted in a significant decrease of lipophorin-containing vesicles, indicative of recycling of the ligand...
  8. ncbi request reprint Insect lipoprotein biogenesis depends on an amphipathic beta cluster in apolipophorin II/I and is stimulated by microsomal triglyceride transfer protein
    Marcel M W Smolenaars
    Division of Endocrinology and Metabolism, Department of Biology and Institute of Biomembranes, Utrecht University, Utrecht, The Netherlands
    J Lipid Res 48:1955-65. 2007
    ..Thus, lipoprotein biogenesis in animals appears to rely on structural elements that are of early metazoan origin...
  9. doi request reprint Circulatory lipid transport: lipoprotein assembly and function from an evolutionary perspective
    Dick J Van der Horst
    Division of Endocrinology and Metabolism, Department of Biology and Institute of Biomembranes, Utrecht University, Padualaan 8, 3584 CH, Utrecht, The Netherlands
    Mol Cell Biochem 326:105-19. 2009
    ..These structural similarities and functional adaptations of the lipid transport systems operative in mammals and insects are discussed from an evolutionary perspective...
  10. ncbi request reprint Lipophorin receptor-mediated lipoprotein endocytosis in insect fat body cells
    Dennis Van Hoof
    Department of Biochemical Physiology and Institute of Biomembranes, Utrecht University, Padualaan 8, 3584 CH Utrecht, The Netherlands
    J Lipid Res 44:1431-40. 2003
    ..These results suggest that iLR mediates endocytosis of HDLp in fat body cells, and that expression of iLR is regulated by the demand of fat body tissue for lipids...
  11. ncbi request reprint Insect lipoprotein follows a transferrin-like recycling pathway that is mediated by the insect LDL receptor homologue
    Dennis Van Hoof
    Department of Biochemical Physiology and Institute of Biomembranes, Utrecht University, Padualaan 8, 3584 CH Utrecht, The Netherlands
    J Cell Sci 115:4001-12. 2002
    ....
  12. doi request reprint Locust flight activity as a model for hormonal regulation of lipid mobilization and transport
    Dick J Van der Horst
    Division of Endocrinology and Metabolism, Department of Biology and Institute of Biomembranes, Utrecht University, Utrecht, The Netherlands
    J Insect Physiol 56:844-53. 2010
    ..Current studies in this field employing the locust as a model continue to attribute to its role as a favored model organism, but also reveal some disadvantages compared to model insects with a completely sequenced genome...
  13. ncbi request reprint Sequence analysis of the non-recurring C-terminal domains shows that insect lipoprotein receptors constitute a distinct group of LDL receptor family members
    Kees W Rodenburg
    Faculty of Biology and Institute of Biomembranes, Department of Biochemical Physiology, Utrecht University, Padualaan 8, 3584 CH Utrecht, The Netherlands
    Insect Biochem Mol Biol 36:250-63. 2006
    ..These features might explain the functional differences disclosed between insect and mammalian lipoprotein receptors...
  14. doi request reprint Insulin-induced translocation of CD36 to the plasma membrane is reversible and shows similarity to that of GLUT4
    Masja M van Oort
    Division of Endocrinology and Metabolism, Department of Biology and Institute of Biomembranes, Utrecht University, NL 3584 CH Utrecht, The Netherlands
    Biochim Biophys Acta 1781:61-71. 2008
    ..Taken together, this study is the first to present morphological evidence for CD36 translocation, and shows this process to resemble GLUT4 translocation...
  15. ncbi request reprint Molecular diversity and evolution of the large lipid transfer protein superfamily
    Marcel M W Smolenaars
    Biochemical Physiology, Department of Biology and Institute of Biomembranes, Faculty of Science, Utrecht University, Utrecht, The Netherlands
    J Lipid Res 48:489-502. 2007
    ..Accordingly, comparative research exposes the structural and functional adaptations in animal lipid carriers and brings up novel possibilities for the manipulation of lipid transport...
  16. ncbi request reprint Lipoprotein-mediated lipid transport in insects: analogy to the mammalian lipid carrier system and novel concepts for the functioning of LDL receptor family members
    Kees W Rodenburg
    Department of Biochemical Physiology, Faculty of Biology and Institute of Biomembranes, Utrecht University, Padualaan 8, 3584 CH Utrecht, The Netherlands
    Biochim Biophys Acta 1736:10-29. 2005
    ....
  17. ncbi request reprint Cell biology of the adipokinetic hormone-producing neurosecretory cells in the locust corpus cardiacum
    Jacques H B Diederen
    Department of Biochemical Physiology, Faculty of Biology, Utrecht University, 3584 CH Utrecht, The Netherlands
    Microsc Res Tech 56:227-36. 2002
    ..Apparently, a coupling between release and biosynthesis of the AKHs in the adipokinetic cells is very loose or does not even exist...
  18. ncbi request reprint Biosynthesis and secretion of insect lipoprotein: involvement of furin in cleavage of the apoB homolog, apolipophorin-II/I
    Marcel M W Smolenaars
    Department of Biochemical Physiology, Faculty of Biology, Institute of Biomembranes, Utrecht University, Utrecht, The Netherlands
    J Lipid Res 46:412-21. 2005
    ..We propose that cleavage enables specific features of insect lipoproteins, such as low density lipoprotein formation, endocytic recycling, and involvement in coagulation...
  19. ncbi request reprint Coherence between biosynthesis and secretion of insect adipokinetic hormones
    Lucien F Harthoorn
    Department of Biochemical Physiology, Utrecht University, The, Utrecht, Netherlands
    Peptides 23:629-34. 2002
    ..It is concluded that AKH secretion involves a regulated release from a relatively small pool of newly formed secretory granules, while older AKH-containing granules appear to be unavailable for release...