Research Topics
| D J L G SchutterSummaryAffiliation: Utrecht University Country: The Netherlands Publications
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Detail Information
Publications
Unmasking feigned sanity: a neurobiological model of emotion processing in primary psychopathyJack van Honk
Utrecht University, The Netherlands
Cogn Neuropsychiatry 11:285-306. 2006....
Fearful faces selectively increase corticospinal motor tract excitability: a transcranial magnetic stimulation studyDennis J L G Schutter
Experimental Psychology, Helmholtz Institute, Utrecht University, Utrecht, The Netherlands
Psychophysiology 45:345-8. 2008..These findings provide the first direct evidence for selective increases in CST excitability to threat and contribute to evolutionary views on emotion and action preparedness...
The cerebello-hypothalamic-pituitary-adrenal axis dysregulation hypothesis in depressive disorderDennis J L G Schutter
Experimental Psychology, Helmholtz Institute, Utrecht University, Utrecht, The Netherlands
Med Hypotheses 79:779-83. 2012..The present hypothesis may further contribute to contemporary neurobiological views on stress regulation and depressive disorder, and may offer a potential biological basis for developing novel neurosomatic treatment protocols...
The cerebellum link to neuroticism: a volumetric MRI association study in healthy volunteersDennis J L G Schutter
Experimental Psychology, Helmholtz Institute, Utrecht University, Utrecht, The Netherlands
PLoS ONE 7:e37252. 2012..In conclusion, cerebellar volumes may constitute a clinico-neuroanatomical correlate for the development of depression- and anxiety-related symptoms...
The cerebellum in emotion regulation: a repetitive transcranial magnetic stimulation studyDennis J L G Schutter
Experimental Psychology, Helmholtz Research Institute, Utrecht University, Utrecht, The Netherlands
Cerebellum 8:28-34. 2009..In order to clarify the underlying biological mechanisms involved, more research is needed...
Quantitative review of the efficacy of slow-frequency magnetic brain stimulation in major depressive disorderD J L G Schutter
Experimental Psychology, Utrecht University, The Netherlands
Psychol Med 40:1789-95. 2010..Nine double-blind sham-controlled parallel intention-to-treat studies (252 patients) fulfilled inclusion criteria and were entered in a random-effects meta-analysis...
Retinal origin of phosphenes to transcranial alternating current stimulationDennis J L G Schutter
Experimental Psychology, Helmholtz Research Institute, Utrecht University, Heidelberglaan 2, 3584CS Utrecht, The Netherlands
Clin Neurophysiol 121:1080-4. 2010..To examine possible retinal contributions to cortically induced phosphenes by transcranial alternating current stimulation (tACS) involving the visual cortex...
[Transcranial magnetic stimulation and cerebral physiology in psychiatric disorders]D J L G Schutter
Tijdschr Psychiatr 51:97-105. 2009..Transcranial magnetic stimulation (tms) is a technique that is being used increasingly to investigate the biological precursors of psychiatric disorders...
Corticospinal state variability and hemispheric asymmetries in motivational tendenciesDennis J L G Schutter
Department of Experimental Psychology, Utrecht University, Heidelberglaan 2, 3584 CS Utrecht, The Netherlands
Biol Psychol 87:450-2. 2011..This study demonstrates that MEP variability may provide an additional means for studying non-stationary properties of corticospinal excitability in relation to hemispheric asymmetries and motivational tendencies...
Brain oscillations and frequency-dependent modulation of cortical excitabilityDennis J L G Schutter
Experimental Psychology, Utrecht University, Utrecht, The Netherlands
Brain Stimul 4:97-103. 2011..The observed clinical effects are in the moderate range and it has been suggested that the efficiency of brain stimulation depends on the underlying cortical state...
[Transcranial magnetic stimulation as a treatment for depression]D J L G Schutter
Universitair Hoofddocent Verbonden aan de Afdeling Psychologische Functieleer aan de Universiteit van Utrecht
Tijdschr Psychiatr 53:343-53. 2011..Transcranial magnetic stimulation (TMS) is a form of non-invasive brain stimulation that has been investigated in the last 15 years in order to find out whether this form of stimulation is effective in the treatment of depression...
Increased sensitivity for angry faces in depressive disorder following 2 weeks of 2-Hz repetitive transcranial magnetic stimulation to the right parietal cortexDennis J L G Schutter
Department of Experimental Psychology, Utrecht University, Utrecht, The Netherlands
Int J Neuropsychopharmacol 13:1155-61. 2010..These results provide the first preliminary support for the cognitive neuropsychological hypothesis of antidepressant action in rTMS treatment...
High-frequency repetitive transcranial magnetic stimulation to the cerebellum and implicit processing of happy facial expressionsDennis J L G Schutter
Department of Experimental Psychology, Helmholtz Institute, Utrecht University, Utrecht, The Netherlands
J Psychiatry Neurosci 34:60-5. 2009..We sought to further explore the effects of cerebellar high-frequency rTMS on implicit processing of emotional stimuli and mood...
Partial clinical response to 2 weeks of 2 Hz repetitive transcranial magnetic stimulation to the right parietal cortex in depressionDennis J L G Schutter
Department of Experimental Psychology, Utrecht University, Utrecht, The Netherlands
Int J Neuropsychopharmacol 12:643-50. 2009..8%) compared to the sham rTMS treatment (6.3%). This study provides the first evidence showing that 2 Hz rTMS over the right parietal cortex may have antidepressant properties, and warrants further research...
An endocrine perspective on the role of steroid hormones in the antidepressant treatment efficacy of transcranial magnetic stimulationDennis J L G Schutter
Experimental Psychology, Helmholtz Institute, Utrecht University, Heidelberglaan 2, 3584CS Utrecht, The Netherlands
Psychoneuroendocrinology 35:171-8. 2010..Here we propose that the measurement and manipulation of steroid hormones could be crucial steps in the development of successful individually based TMS protocols for the treatment of MDD...
Antidepressant efficacy of high-frequency transcranial magnetic stimulation over the left dorsolateral prefrontal cortex in double-blind sham-controlled designs: a meta-analysisD J L G Schutter
Experimental Psychology, Utrecht University, Utrecht, The Netherlands
Psychol Med 39:65-75. 2009..The aim of this study was to provide an update on its clinical efficacy by performing a meta-analysis involving double-blind sham-controlled studies...
Testosterone reduces unconscious fear but not consciously experienced anxiety: implications for the disorders of fear and anxietyJack van Honk
Helmholtz Research Institute, Affective Neuroscience Section, Utrecht University, Heidelberglaan 2, 3585 CS Utrecht, The Netherlands
Biol Psychiatry 58:218-25. 2005..Presently, it was hypothesized that a single testosterone administration to humans would reduce unconscious fear but not consciously experienced anxiety...
Testosterone reduces conscious detection of signals serving social correction: implications for antisocial behaviorJack van Honk
Department of Psychology, Experimental Psychology, Utrecht University, Utrecht, The Netherlands
Psychol Sci 18:663-7. 2007..This testosterone-induced impairment in the conscious detection of the socially corrective facial signal of anger may predispose individuals to antisocial behavior...
1 hz rTMS over the right prefrontal cortex reduces vigilant attention to unmasked but not to masked fearful facesJack van Honk
Helmholtz Research Institute, Affective Neuroscience Section, Utrecht University, The, Utrecht, Netherlands
Biol Psychiatry 52:312-7. 2002..In addition, the absence of an effect for masked fearful faces suggests that changes in emotional processing after a single session of rTMS predominantly involve the cortical affective pathways...
TMS pulses on the frontal eye fields break coupling between visuospatial attention and eye movementsS F W Neggers
Experimental Psychology, Helmholtz Institute, Utrecht University, The Netherlands
J Neurophysiol 98:2765-78. 2007....
High frequency repetitive transcranial magnetic over the medial cerebellum induces a shift in the prefrontal electroencephalography gamma spectrum: a pilot study in humansDennis J L G Schutter
Affective Neuroscience Section, Helmholtz Research Institute, Utrecht University, Heidelberglaan 2, 3584 CS Utrecht, The Netherlands
Neurosci Lett 336:73-6. 2003..Moreover elevations in mood and alertness were reported again after medial cerebellar stimulation only. Taken together, these data confirm and further specify the assumed cerebellar modulation of PFC activity and affect...
Reductions in phenomenological, physiological and attentional indices of depressive mood after 2 Hz rTMS over the right parietal cortex in healthy human subjectsJack van Honk
Helmholtz Research Institute, Utrecht University, Heidelberglaan 2, 3584 CS, Utrecht, The Netherlands
Psychiatry Res 120:95-101. 2003..These data suggest a role for the right parietal cortex in affective brain circuits regulating phenomenological, physiological and attentional aspects of depressive functioning...
Baseline EEG theta/beta ratio and punishment sensitivity as biomarkers for feedback-related negativity (FRN) and risk-takingS A A Massar
Department of Experimental Psychology, Helmholtz Institute, Utrecht University, Utrecht, The Netherlands
Clin Neurophysiol 123:1958-65. 2012..In this study it was examined whether there was a relation between baseline theta/beta ratio in rest and FRN amplitude during a gambling task, and if such a correlation would be related to theta activity or to beta activity...
Subjective impulsivity and baseline EEG in relation to stopping performanceMarieke M Lansbergen
Departments of Experimental Psychology and Psychopharmacology, Utrecht University, Heidelberglaan 2, 3584 CS Utrecht, The Netherlands
Brain Res 1148:161-9. 2007....
Is this hand for real? Attenuation of the rubber hand illusion by transcranial magnetic stimulation over the inferior parietal lobuleMarjolein P M Kammers
Helmholtz Institute, Experimental Psychology, Utrecht University, Utrecht, The Netherlands
J Cogn Neurosci 21:1311-20. 2009....
Inside the wire: aggression and functional interhemispheric connectivity in the human brainDennis Hofman
Experimental Psychology, Helmholtz Institute, Utrecht University, Utrecht, The Netherlands
Psychophysiology 46:1054-8. 2009..We conclude that an aggressive personality style and selective attention to angry faces are positively correlated with functional interhemispheric connectivity...
Alcohol breaks down interhemispheric inhibition in females but not in males: alcohol and frontal connectivitySylco S Hoppenbrouwers
Department of Experimental Psychology, Helmholtz Research Institute, Utrecht University, Heidelberglaan 2, 3584 CS Utrecht, The Netherlands
Psychopharmacology (Berl) 208:469-74. 2010..Alcohol has renowned behavioral disinhibitory properties which are suggested to involve reductions in frontal lobe functioning as a result of diminished interhemispheric connectivity...
Socially explosive minds: the triple imbalance hypothesis of reactive aggressionJack van Honk
Department of Psychology, Experimental Psychology, Utrecht University, Heidelberglaan2, 3584 CS Utrecht, The Netherlands
J Pers 78:67-94. 2010..This triple biobehavioral imbalance mirrors an evolutionary relapse into violently aggressive motivational drives that are adaptive among many reptilian and mammalian species, but may have become socially maladaptive in modern humans...
A left-prefrontal lateralized, sympathetic mechanism directs attention towards social threat in humans: evidence from repetitive transcranial magnetic stimulationJack van Honk
Helmholtz Research Institute, Affective Neuroscience Section, Utrecht University, Heidelberglaan 2, 3584 CS Utrecht, The Netherlands
Neurosci Lett 319:99-102. 2002..Our data suggest that a left-PFC lateralized, sympathetic mechanism directs attention towards the angry facial expression...
An electrophysiological link between the cerebellum, cognition and emotion: frontal theta EEG activity to single-pulse cerebellar TMSDennis J L G Schutter
Helmholtz Research Institute, Experimental Psychology Utrecht University, Heidelberglaan 2, 3584 CS Utrecht, The Netherlands
Neuroimage 33:1227-31. 2006....
Extending the global workspace theory to emotion: phenomenality without accessDennis J L G Schutter
Affective Neuroscience Section, Helmholtz Research Institute, Utrecht University, Utrecht, The Netherlands
Conscious Cogn 13:539-49. 2004..The current finding suggests that EEG coherence is modulated by unconscious emotional processes, which extends common views on the global workspace architecture of consciousness...
Reductions in CI amplitude after repetitive transcranial magnetic stimulation (rTMS) over the striate cortexDennis J L G Schutter
Affective Neuroscience Section, Helmholtz Research Institute, Utrecht University, Heidelberglaan 2, 3584 CS Utrecht, The Netherlands
Brain Res Cogn Brain Res 16:488-91. 2003..The present study provides causal evidence for the involvement of the striate cortex in generating the CI component...
Electrophysiological ratio markers for the balance between reward and punishmentDennis J L G Schutter
Helmholtz Research Institute, Affective Neuroscience Section, Utrecht University, Heidelberglaan 2, 3584 CS Utrecht, The Netherlands
Brain Res Cogn Brain Res 24:685-90. 2005..This finding provides the first direct evidence that the electrophysiologically derived EEG ratios can serve as biological markers for balance and imbalance in motivation...
Administration of testosterone increases functional connectivity in a cortico-cortical depression circuitDennis J L G Schutter
Helmholtz Research Institute, Affective Neuroscience Section, Utrecht University, Heidelberglaan 2, 3584 CS Utrecht, The Netherlands
J Neuropsychiatry Clin Neurosci 17:372-7. 2005..The fact that only a single dose of T was able to induce the effect in healthy female subjects suggests that the mechanism is highly sensitive. A feasible application of T treatment in the struggle against depression is discussed...
Functionally dissociated aspects in anterior and posterior electrocortical processing of facial threatDennis J L G Schutter
Helmholtz Research Institute, Affective Neuroscience Section, Utrecht University, Heidelberglaan 2, 3584 CS, Utrecht, The Netherlands
Int J Psychophysiol 53:29-36. 2004..The more pronounced posterior eCNV suggests sustained attention to socially threatening information...
From affective valence to motivational direction: the frontal asymmetry of emotion revisedJack van Honk
Helmholtz Research Institute, Department of Psychology, Utrecht University, Utrecht, The Netherlands
Psychol Sci 17:963-5. 2006
A case of illusory own-body perceptions after transcranial magnetic stimulation of the cerebellumDennis J L G Schutter
Experimental Psychology, Helmholtz Research Institute, Utrecht University, Utrecht, The Netherlands
Cerebellum 5:238-40. 2006..The data provide the first evidence that the cerebellum might be involved in a neuronal network underlying illusory own-body perceptions...
Increased positive emotional memory after repetitive transcranial magnetic stimulation over the orbitofrontal cortexDennis J L G Schutter
Department of Psychonomics, Affective Neuroscience Section, Helmholtz Research Institute, Utrecht University, Utrecht, The Netherlands
J Psychiatry Neurosci 31:101-4. 2006..The aim of the present study was to investigate whether slow, inhibitory repetitive transcranial magnetic stimulation (rTMS) over the left OFC would improve memory for positive material...
A stereotactic method for image-guided transcranial magnetic stimulation validated with fMRI and motor-evoked potentialsS F W Neggers
Department of Psychonomics, Helmholtz Institute, Utrecht University, Utrecht, The Netherlands
Neuroimage 21:1805-17. 2004..The present results demonstrate that NeNa is a reliable method for image-guided TMS coil placement...
Cortisol, depression and reduced cortico-cortical cross-talk in Cushing's syndromeD J L G Schutter
Affective Neuroscience Section, Helmholtz Research Institute, Utrecht University, The Netherlands
J Endocrinol Invest 27:683-6. 2004..These findings provide preliminary evidence for the hypothesis that loss of cortico-cortical cross-talk might be linked to hypercortisolism and the severity of depressive symptoms...
Scaling problems in the brain-mind conundrumDennis J L G Schutter
Department of Psychonomics, Affective Neuroscience Section, Helmholtz Institute, Utrecht University, Utrecht, The Netherlands
Cortex 42:411-3; discussion 422-7. 2006
A standardized motor threshold estimation procedure for transcranial magnetic stimulation researchDennis J L G Schutter
Experimental Psychology, Helmholtz Research Institute, Utrecht University, Utrecht, The Netherlands
J ECT 22:176-8. 2006..To introduce and to test a simple standardized motor threshold (MT) estimation procedure for transcranial magnetic stimulation (TMS) research...
Functional anatomy of top-down visuospatial processing in the human brain: evidence from rTMSAndre Aleman
Helmholtz Instituut, Psychological Laboratory, Utrecht University, Heidelberglaan 2, Utrecht, The Netherlands
Brain Res Cogn Brain Res 14:300-2. 2002..Performance deteriorated significantly after rTMS over the parietal, but not occipital, cortex. These data support a causal link between parietal activation and top-down spatial processing...
Testosterone shifts the balance between sensitivity for punishment and reward in healthy young womenJack van Honk
Affective Neuroscience Section, Psychonomics, Helmholtz Research Institute, Utrecht University, Heidelberglaan 2, 3584 CS Utrecht, The Netherlands
Psychoneuroendocrinology 29:937-43. 2004..These findings not only provide the first direct evidence for the effects of testosterone on punishment-reward contingencies in humans, but they also give further insights into the hypothetical link between testosterone and psychopathy...
Defective somatic markers in sub-clinical psychopathyJack van Honk
Helmholtz Research Institute, Affective Neuroscience Section, Utrecht University, Heidelberglaan 2, 3584 CS Utrecht, The Netherlands
Neuroreport 13:1025-7. 2002..These findings provide further evidence for the hypothesized link between psychopathy and orbitofrontal dysfunction...
A framework for targeting alternative brain regions with repetitive transcranial magnetic stimulation in the treatment of depressionDennis J L G Schutter
Affective Neuroscience Section, Helmholtz Research Institute, Utrecht University, Utrecht, The Netherlands
J Psychiatry Neurosci 30:91-7. 2005....
The cerebellum on the rise in human emotionDennis J L G Schutter
Affective Neuroscience Section, Department of Psychonomics, Helmholtz Research Institute, Utrecht University, Utrecht, The Netherlands
Cerebellum 4:290-4. 2005..Research shows that the functional repertoire of the cerebellum is broader than previously thought and its involvement in emotion is noteworthy...
Interrelations between motivational stance, cortical excitability, and the frontal electroencephalogram asymmetry of emotion: a transcranial magnetic stimulation studyDennis J L G Schutter
Department of Experimental Psychology, Utrecht University, The Netherlands d schutter fss uu nl
Hum Brain Mapp 29:574-80. 2008....
Electrophysiological correlates of cortico-subcortical interaction: a cross-frequency spectral EEG analysisDennis J L G Schutter
Department of Psychonomics, Affective Neuroscience Section, Helmholtz Research Institute, Utrecht University, Heidelberglaan 2, 3584CS Utrecht, The Netherlands
Clin Neurophysiol 117:381-7. 2006..To get further insights into these mechanisms, the current study investigated whether CSC-ct would decrease as a function of increased slow (SW) or fast wave (FW) activity...
Low cortisol levels and the balance between punishment sensitivity and reward dependencyJack van Honk
Helmholtz Research Institute, Utrecht University, Utrecht, The Netherlands
Neuroreport 14:1993-6. 2003..These findings suggest that low levels of cortisol may set the balance between the sensitivity for punishment and reward dependency towards a pre-disposition for psychopathy...
The role of the cerebellum in the pathophysiology and treatment of neuropsychiatric disorders: a reviewSylco S Hoppenbrouwers
Department of Experimental Psychology, Utrecht University, The Netherlands
Brain Res Rev 59:185-200. 2008....
Transcranial magnetic stimulation and processing of facial threatsJack van Honk
Am J Psychiatry 161:928; author reply 928-9. 2004
Anxious apprehension increases coupling of delta and beta oscillationsGennady G Knyazev
State Research Institute of Physiology, Siberian Branch of the Russian Academy of Medical Sciences, Novosibirsk 630117, Russia
Int J Psychophysiol 61:283-7. 2006..Contrariwise, delta-beta coupling appeared only in anxiogenic situation both in high and low anxiety subjects...
Decoupling of midfrontal delta-beta oscillations after testosterone administrationDennis J L G Schutter
Int J Psychophysiol 53:71-3. 2004
Salivary cortisol levels and the coupling of midfrontal delta-beta oscillationsDennis J L G Schutter
Int J Psychophysiol 55:127-9. 2005
