Bert Brunekreef

Summary

Affiliation: Utrecht University
Country: The Netherlands

Publications

  1. ncbi request reprint The prevention and incidence of asthma and mite allergy (PIAMA) birth cohort study: design and first results
    Bert Brunekreef
    Institute for Risk Assessment Sciences, University of Utrecht, Utrecht, The Netherlands
    Pediatr Allergy Immunol 13:55-60. 2002
  2. doi request reprint Exposure science, the exposome, and public health
    Bert Brunekreef
    Institute for Risk Assessment Sciences, Universiteit Utrecht, Utrecht, The Netherlands
    Environ Mol Mutagen 54:596-8. 2013
  3. doi request reprint Acute nasal pro-inflammatory response to air pollution depends on characteristics other than particle mass concentration or oxidative potential: the RAPTES project
    Maaike Steenhof
    Division of Environmental Epidemiology, Institute for Risk Assessment Sciences IRAS, Utrecht University, Utrecht, The Netherlands
    Occup Environ Med 70:341-8. 2013
  4. ncbi request reprint Exposure to cats and dogs, and symptoms of asthma, rhinoconjunctivitis, and eczema
    Bert Brunekreef
    Institute for Risk Assessment Sciences and Julius Center for Health Sciences and Primary Care, University Medical Center Universiteit Utrecht, The Netherlands
    Epidemiology 23:742-50. 2012
  5. doi request reprint Early life exposure to farm animals and symptoms of asthma, rhinoconjunctivitis and eczema: an ISAAC Phase Three Study
    Bert Brunekreef
    Institute for Risk Assessment Sciences and Julius Center for Health Sciences and Primary Care, University Medical Center Universiteit Utrecht, Utrecht, The Netherlands
    Int J Epidemiol 41:753-61. 2012
  6. pmc Expert elicitation on ultrafine particles: likelihood of health effects and causal pathways
    Anne B Knol
    Dutch National Institute for Public Health and the Environment RIVM, Bilthoven, The Netherlands
    Part Fibre Toxicol 6:19. 2009
  7. pmc Long-term exposure to traffic-related air pollution and type 2 diabetes prevalence in a cross-sectional screening-study in the Netherlands
    Marieke B A Dijkema
    Department of Environmental Health, Public Health Service Amsterdam, Amsterdam, The Netherlands
    Environ Health 10:76. 2011
  8. pmc Minute ventilation of cyclists, car and bus passengers: an experimental study
    Moniek Zuurbier
    Public Health Services Gelderland Midden, Arnhem, The Netherlands
    Environ Health 8:48. 2009
  9. pmc Quantification of the energy gap in young overweight children. The PIAMA birth cohort study
    Saskia W van den Berg
    National Institute for Public Health and the Environment, Bilthoven, The Netherlands
    BMC Public Health 11:326. 2011
  10. pmc Comorbidities of obesity in school children: a cross-sectional study in the PIAMA birth cohort
    Alet H Wijga
    Centre for Prevention and Health Services Research, National Institute for Public Health and the Environment, Bilthoven, The Netherlands
    BMC Public Health 10:184. 2010

Detail Information

Publications121 found, 100 shown here

  1. ncbi request reprint The prevention and incidence of asthma and mite allergy (PIAMA) birth cohort study: design and first results
    Bert Brunekreef
    Institute for Risk Assessment Sciences, University of Utrecht, Utrecht, The Netherlands
    Pediatr Allergy Immunol 13:55-60. 2002
    ....
  2. doi request reprint Exposure science, the exposome, and public health
    Bert Brunekreef
    Institute for Risk Assessment Sciences, Universiteit Utrecht, Utrecht, The Netherlands
    Environ Mol Mutagen 54:596-8. 2013
    ..This commentary discusses recent developments in exposure science and their potential contribution to improving public health...
  3. doi request reprint Acute nasal pro-inflammatory response to air pollution depends on characteristics other than particle mass concentration or oxidative potential: the RAPTES project
    Maaike Steenhof
    Division of Environmental Epidemiology, Institute for Risk Assessment Sciences IRAS, Utrecht University, Utrecht, The Netherlands
    Occup Environ Med 70:341-8. 2013
    ..To investigate which air pollution characteristics are associated with biomarkers for acute nasal airway inflammation in healthy subjects. We hypothesised that associations would be strongest for oxidative potential (OP) of particles...
  4. ncbi request reprint Exposure to cats and dogs, and symptoms of asthma, rhinoconjunctivitis, and eczema
    Bert Brunekreef
    Institute for Risk Assessment Sciences and Julius Center for Health Sciences and Primary Care, University Medical Center Universiteit Utrecht, The Netherlands
    Epidemiology 23:742-50. 2012
    ..Associations between exposure to cats and dogs and respiratory and allergic outcomes in children have been reported in affluent countries, but little is known about such associations in less-affluent countries...
  5. doi request reprint Early life exposure to farm animals and symptoms of asthma, rhinoconjunctivitis and eczema: an ISAAC Phase Three Study
    Bert Brunekreef
    Institute for Risk Assessment Sciences and Julius Center for Health Sciences and Primary Care, University Medical Center Universiteit Utrecht, Utrecht, The Netherlands
    Int J Epidemiol 41:753-61. 2012
    ..Associations between early life exposure to farm animals and respiratory symptoms and allergy in children have been reported in developed countries, but little is known about such associations in developing countries...
  6. pmc Expert elicitation on ultrafine particles: likelihood of health effects and causal pathways
    Anne B Knol
    Dutch National Institute for Public Health and the Environment RIVM, Bilthoven, The Netherlands
    Part Fibre Toxicol 6:19. 2009
    ..abstract:..
  7. pmc Long-term exposure to traffic-related air pollution and type 2 diabetes prevalence in a cross-sectional screening-study in the Netherlands
    Marieke B A Dijkema
    Department of Environmental Health, Public Health Service Amsterdam, Amsterdam, The Netherlands
    Environ Health 10:76. 2011
    ..This study examined the relation between long-term exposure to traffic-related air pollution and type 2 diabetes prevalence among 50- to 75-year-old subjects living in Westfriesland, the Netherlands...
  8. pmc Minute ventilation of cyclists, car and bus passengers: an experimental study
    Moniek Zuurbier
    Public Health Services Gelderland Midden, Arnhem, The Netherlands
    Environ Health 8:48. 2009
    ..This study estimates minute ventilation of cyclists, car and bus passengers, as part of a study on health effects of commuters' exposure to air pollutants...
  9. pmc Quantification of the energy gap in young overweight children. The PIAMA birth cohort study
    Saskia W van den Berg
    National Institute for Public Health and the Environment, Bilthoven, The Netherlands
    BMC Public Health 11:326. 2011
    ..Aim of this study was to quantify the positive energy balance responsible for excess body weight gain (energy gap) in young overweight children...
  10. pmc Comorbidities of obesity in school children: a cross-sectional study in the PIAMA birth cohort
    Alet H Wijga
    Centre for Prevention and Health Services Research, National Institute for Public Health and the Environment, Bilthoven, The Netherlands
    BMC Public Health 10:184. 2010
    ....
  11. pmc Prescription of respiratory medication without an asthma diagnosis in children: a population based study
    Mira G P Zuidgeest
    Department of Pharmacoepidemiology and Pharmacotherapy, Utrecht Institute for Pharmaceutical Sciences UIPS, Utrecht University, The Netherlands
    BMC Health Serv Res 8:16. 2008
    ..The aim of this study is to evaluate the relationship between prescribing of asthma medication and doctor-diagnosed asthma in children age 0-17...
  12. doi request reprint Health effects of air pollution observed in cohort studies in Europe
    Bert Brunekreef
    Department of Environmental Epidemiology, Institute for Risk Assessment Sciences and Julius Center for Health Sciences and Primary Care, Universiteit Utrecht, PO Box 80178, Utrecht 3508 TD, The Netherlands
    J Expo Sci Environ Epidemiol 17:S61-5. 2007
    ..The results of a number of recent European studies are discussed...
  13. pmc Self-reported truck traffic on the street of residence and symptoms of asthma and allergic disease: a global relationship in ISAAC phase 3
    Bert Brunekreef
    Institute for Risk Assessment Sciences and Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands
    Environ Health Perspect 117:1791-8. 2009
    ..Associations between traffic pollution on the street of residence and a range of respiratory and allergic outcomes in children have been reported in developed countries, but little is known about such associations in developing countries...
  14. doi request reprint Environmental epidemiology and risk assessment
    Bert Brunekreef
    Institute for Risk Assessment Sciences, Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Universiteit Utrecht, PO Box 80178, 3508 TD Utrecht, The Netherlands
    Toxicol Lett 180:118-22. 2008
    ..Examples are provided for each of these. The strengths and weaknesses compared to experimental toxicology studies are discussed...
  15. doi request reprint Traffic-related air pollution is related to interrupter resistance in 4-year-old children
    Esther Eenhuizen
    Institute for Risk Assessment Sciences, Utrecht University, Utrecht, The Netherlands
    Eur Respir J 41:1257-63. 2013
    ....
  16. ncbi request reprint Childhood cat allergen exposure in three European countries: The AIRALLERG study
    Mariëlla Giovannangelo
    Division of Environmental and Occupational Health, Institute for Risk Assessment Sciences, Utrecht University, Utrecht, The Netherlands
    Sci Total Environ 369:82-90. 2006
    ..Cat allergen is a major cause of morbidity among sensitised asthma patients, but little is known about distribution of cat allergen exposure and its determinants in homes...
  17. doi request reprint Impact of low emission zones and local traffic policies on ambient air pollution concentrations
    Hanna Boogaard
    Institute for Risk Assessment Sciences IRAS, Division Environmental Epidemiology, Utrecht University, Utrecht, Netherlands
    Sci Total Environ 435:132-40. 2012
    ..This study investigated air pollution at street level before and after implementation of local traffic policies including low emission zones (LEZ) directed at heavy duty vehicles (trucks) in five Dutch cities...
  18. doi request reprint Traffic-related air pollution and the development of asthma and allergies during the first 8 years of life
    Ulrike Gehring
    Institute for Risk Assessment Sciences, Utrecht University, The Netherlands
    Am J Respir Crit Care Med 181:596-603. 2010
    ..The role of air pollution exposure in the development of asthma, allergies, and related symptoms remains unclear, due in part to the limited number of prospective cohort studies with sufficiently long follow-ups addressing this problem...
  19. doi request reprint Respiratory effects of a reduction in outdoor air pollution concentrations
    Hanna Boogaard
    Institute for Risk Assessment Sciences, Division Environmental Epidemiology, Utrecht University, Utrecht, Netherlands
    Epidemiology 24:753-61. 2013
    ..We assessed whether a reduction in (traffic policy-related) air pollution concentrations was associated with changes in respiratory health...
  20. doi request reprint Do differences in childhood diet explain the reduced overweight risk in breastfed children?
    Salome Scholtens
    Institute for Risk Assessment Sciences, Utrecht University, Utrecht, The Netherlands
    Obesity (Silver Spring) 16:2498-503. 2008
    ..71, 95% confidence interval: 0.49-1.03). Breastfed children had a healthier diet at 7 years compared to nonbreastfed children, but this difference could not explain the lower overweight risk at 8 years in breastfed children...
  21. pmc Contrasts in oxidative potential and other particulate matter characteristics collected near major streets and background locations
    Hanna Boogaard
    Institute for Risk Assessment Sciences, Division Environmental Epidemiology, Utrecht University, Utrecht, The Netherlands
    Environ Health Perspect 120:185-91. 2012
    ..Measuring the oxidative potential of airborne particulate matter (PM) may provide a more health-based exposure measure by integrating various biologically relevant properties of PM into a single predictor of biological activity...
  22. doi request reprint Overweight and changes in weight status during childhood in relation to asthma symptoms at 8 years of age
    Salome Scholtens
    Institute for Risk Assessment Sciences, Utrecht University, Utrecht, The Netherlands
    J Allergy Clin Immunol 123:1312-8.e2. 2009
    ..Asthma may be more prevalent in overweight children. However, how early overweight and changes in weight status during childhood affect the asthma risk is unclear...
  23. doi request reprint Waist circumference, BMI, and lung function in 8-year-old children: the PIAMA birth cohort study
    Marga B M Bekkers
    Institute for Risk Assessment Sciences IRAS, Utrecht University, Utrecht, The Netherlands
    Pediatr Pulmonol 48:674-82. 2013
    ..Body mass index (BMI) and waist circumference (WC) may be associated with lung function in children, as observed in adults...
  24. doi request reprint Gas cooking, respiratory and allergic outcomes in the PIAMA birth cohort study
    WeiWei Lin
    Institute for Risk Assessment Sciences, Utrecht University, Utrecht, The Netherlands
    Occup Environ Med 70:187-94. 2013
    ..Our aim was to examine the association between gas cooking and the development of respiratory and allergic outcomes longitudinally in a prospective birth cohort study...
  25. doi request reprint Asthma therapy during the first 8 years of life: a PIAMA cohort study
    Mira G P Zuidgeest
    Division of Pharmacoepidemiology and Pharmacotherapy, Utrecht Institute for Pharmaceutical Sciences UIPS, Faculty of Science, Utrecht University, 3508 TB Utrecht, The Netherlands
    J Asthma 47:209-13. 2010
    ..This study describes the formation of a longitudinal data set on asthma medication use and shows first results regarding the prevalence and incidence of medication use...
  26. doi request reprint Uncontrolled asthma at age 8: the importance of parental perception towards medication
    Ellen S Koster
    Division of Pharmacoepidemiology and Pharmacotherapy, Utrecht Institute for Pharmaceutical Sciences UIPS, Faculty of Science, Utrecht University, Utrecht, The Netherlands
    Pediatr Allergy Immunol 22:462-8. 2011
    ..The aim of this study was to identify determinants of uncontrolled asthma at age 8 in children participating in the PIAMA birth cohort study...
  27. ncbi request reprint Levels and determinants of beta(1-->3)-glucans and fungal extracellular polysaccharides in house dust of (pre-)school children in three European countries
    Mariëlla E C A Giovannangelo
    Utrecht University, Institute for Risk Assessment Sciences, Utrecht, The Netherlands
    Environ Int 33:9-16. 2007
    ..Measurements of beta(1-->3)-glucans and fungal extracellular polysaccharides (EPS) are used as markers of mold exposure in field studies. Little is known about their levels and determinants in homes...
  28. doi request reprint Traffic-related air pollution, preterm birth and term birth weight in the PIAMA birth cohort study
    Ulrike Gehring
    Institute for Risk Assessment Sciences, Utrecht University, PO Box 80178, 3508 TD Utrecht, The Netherlands
    Environ Res 111:125-35. 2011
    ..Maternal exposure to air pollution has been associated with adverse pregnancy outcomes. Few studies took into account the spatial and temporal variation of air pollution levels...
  29. doi request reprint High agreement between parental reported inhaled corticosteroid use and pharmacy prescription data
    Ellen S Koster
    Division of Pharmacoepidemiology and Pharmacotherapy, Faculty of Science, Utrecht Institute for Pharmaceutical Sciences UIPS, Utrecht University, Utrecht, The Netherlands
    Pharmacoepidemiol Drug Saf 19:1199-203. 2010
    ..This study was conducted to assess the validity of parental reported use of inhaled corticosteroids (ICS) in children...
  30. ncbi request reprint Does early indoor microbial exposure reduce the risk of asthma? The Prevention and Incidence of Asthma and Mite Allergy birth cohort study
    Jeroen Douwes
    Institute for Risk Assessment Sciences IRAS, Utrecht University, Amsterdam
    J Allergy Clin Immunol 117:1067-73. 2006
    ..Exposure to microbial agents might inhibit the development of atopy and asthma...
  31. doi request reprint Traffic-related outdoor air pollution and respiratory symptoms in children: the impact of adjustment for exposure measurement error
    Sofie van Roosbroeck
    Environmental Epidemiology Group, Institute for Risk Assessment Sciences, Utrecht University, Utrecht, The Netherlands
    Epidemiology 19:409-16. 2008
    ..Outdoor concentrations of soot and nitrogen dioxide (NO2) outside of schools have been associated with children's respiratory and eye symptoms. We assessed how adjustments for measurement error affect these associations...
  32. pmc BMI development of normal weight and overweight children in the PIAMA study
    Saskia M Willers
    Institute for Risk Assessment Sciences, Division Environmental Epidemiology, Utrecht University, Utrecht, The Netherlands
    PLoS ONE 7:e39517. 2012
    ..There is evidence that rapid weight gain during the first year of life is associated with overweight later in life. However, results from studies exploring other critical periods for the development of overweight are inconsistent...
  33. doi request reprint Maternal food consumption during pregnancy and the longitudinal development of childhood asthma
    Saskia M Willers
    Institute for Risk Assessment Sciences, Division of Environmental Epidemiology, Utrecht University, P O Box 80178, 3508 TD Utrecht, The Netherlands
    Am J Respir Crit Care Med 178:124-31. 2008
    ..Maternal diet during pregnancy has the potential to affect airway development and to promote T-helper-2-cell responses during fetal life. This might increase the risk of developing childhood asthma or allergy...
  34. doi request reprint Blood pressure in 12-year-old children is associated with fatty acid composition of human milk: the prevention and incidence of asthma and mite allergy birth cohort
    Lenie van Rossem
    Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Universiteitsweg 100, 3584 CG, PO Box 85500, 3508 GA, Utrecht, The Netherlands
    Hypertension 60:1055-60. 2012
    ....
  35. ncbi request reprint Relationship between different size classes of particulate matter and meteorology in three European cities
    Jeroen J de Hartog
    Utrecht University, Institute for Risk Assessment Sciences, Environmental and Occupational Health Division, Jenalaan 18a, 3584 CK Utrecht, The Netherlands
    J Environ Monit 7:302-10. 2005
    ..Since the composition of these particle fractions also differs, it is of interest to test in future epidemiological studies whether they have different health effects...
  36. ncbi request reprint Variation of biocontaminant levels within and between homes--the AIRALLERG study
    Mariëlla Giovannangelo
    Institute for Risk Assessment Sciences, Utrecht University, Utrecht, The Netherlands
    J Expo Sci Environ Epidemiol 17:134-40. 2007
    ..Investigation of variation over time is needed for a more complete assessment of the use of these variables in epidemiological analyses of exposure-response relationships...
  37. doi request reprint Long-term exposure to traffic-related air pollution and lung cancer risk
    Rob Beelen
    Institute for Risk Assessment Sciences, Division Environmental Epidemiology, Utrecht University, Utrecht, The Netherlands
    Epidemiology 19:702-10. 2008
    ..Most studies on the association between lung cancer and air pollution have investigated mortality. There have been few studies of lung cancer incidence...
  38. doi request reprint Patterns of asthma medication use: early asthma therapy initiation and asthma outcomes at age 8
    Ellen S Koster
    Division of Pharmacoepidemiology and Pharmacotherapy, Utrecht Institute for Pharmaceutical Sciences UIPS, Faculty of Science, Utrecht University, Utrecht, The Netherlands
    Pharmacoepidemiol Drug Saf 19:991-9. 2010
    ..ICS and SABA prescription occurs especially in those who were more likely to develop signs of asthma at age 8...
  39. doi request reprint Persistence of asthma medication use in preschool children
    Mira G Zuidgeest
    Division of Pharmacoepidemiology and Pharmacotherapy, Utrecht Institute for Pharmaceutical Sciences, Faculty of Science, Utrecht University, P O BOX 80082, 3508 TB, Utrecht, The Netherlands
    Respir Med 102:1446-51. 2008
    ..Our aim is to quantify the persistent use of asthma medication, initiated in the first year of life and identify determinants of this persistent use...
  40. pmc BMI and waist circumference; cross-sectional and prospective associations with blood pressure and cholesterol in 12-year-olds
    Marga B M Bekkers
    Institute for Risk Assessment Sciences, Utrecht University, Utrecht, The Netherlands
    PLoS ONE 7:e51801. 2012
    ..We studied associations between BMI and WC and blood pressure (BP) and cholesterol in 12-year-old children and prospectively changes in BMI or WC status between age 8 and 12 years and BP and cholesterol at age 12...
  41. doi request reprint Systematic evaluation of land use regression models for NO₂
    Meng Wang
    Institute for Risk Assessment Sciences IRAS, Division of Environmental Epidemiology, Utrecht University, Utrecht, The Netherlands
    Environ Sci Technol 46:4481-9. 2012
    ..In our specific application, models based on as few as 24 training sites, however, achieved acceptable hold out validation R(2)s of, on average, 0.60...
  42. pmc The relationship between air pollution from heavy traffic and allergic sensitization, bronchial hyperresponsiveness, and respiratory symptoms in Dutch schoolchildren
    Nicole A H Janssen
    Department of Environmental Epidemiology, Institute for Risk Assessment Sciences, University of Utrecht, PO Box 80176, 3508 TD Utrecht, The Netherlands
    Environ Health Perspect 111:1512-8. 2003
    ....
  43. doi request reprint Land use regression model for ultrafine particles in Amsterdam
    Gerard Hoek
    Institute for Risk Assessment Sciences IRAS, Division of Environmental Epidemiology, Utrecht University, Utrecht, The Netherlands
    Environ Sci Technol 45:622-8. 2011
    ..5, soot, and coarse particles. A LUR model for PNC has been developed, with similar validity as previous models for more commonly measured pollutants...
  44. pmc Environmental exposure assessment in European birth cohorts: results from the ENRIECO project
    Ulrike Gehring
    Institute for Risk Assessment Sciences, Utrecht University, Utrecht, The Netherlands
    Environ Health 12:8. 2013
    ....
  45. doi request reprint Effect of endotoxin and allergens on neonatal lung function and infancy respiratory symptoms and eczema
    Victoria Abbing-Karahagopian
    Institute for Risk Assessment Sciences, Utrecht University, Utrecht, The Netherlands
    Pediatr Allergy Immunol 23:448-55. 2012
    ..Exposure to endotoxin and allergens in house dust has been found to be associated with childhood wheeze and asthma. Neonatal lung function is rarely examined in relation to this exposure...
  46. pmc Early-life determinants of total and HDL cholesterol concentrations in 8-year-old children; the PIAMA birth cohort study
    Marga B M Bekkers
    Institute for Risk Assessment Sciences, Utrecht University, Utrecht, The Netherlands
    PLoS ONE 6:e25533. 2011
    ....
  47. doi request reprint Long-term exposure to air pollution and vascular damage in young adults
    Virissa Lenters
    Division of Environmental Epidemiology, Institute for Risk Assessment Sciences, Utrecht University, Utrecht, The Netherlands
    Epidemiology 21:512-20. 2010
    ..There are, however, very limited data in healthy young people. We examined the association between air pollutants and indicators of vascular damage in a cohort of young adults...
  48. pmc Long-term effects of traffic-related air pollution on mortality in a Dutch cohort (NLCS-AIR study)
    Rob Beelen
    Institute for Risk Assessment Sciences, Division Environmental Epidemiology, Utrecht University, Utrecht, The Netherlands
    Environ Health Perspect 116:196-202. 2008
    ..Several studies have found an effect on mortality of between-city contrasts in long-term exposure to air pollution. The effect of within-city contrasts is still poorly understood...
  49. doi request reprint Parental reported compared with measured waist circumference in 8-year-old children
    Marga B M Bekkers
    Institute for Risk Assessment Sciences, Utrecht University, Utrecht, The Netherlands
    Int J Pediatr Obes 6:e78-86. 2011
    ..In this study the agreement between parental reported and measured WC in 8-year-old children was investigated and compared with the agreement between parental reported and measured body mass index (BMI)...
  50. doi request reprint Long-chain polyunsaturated fatty acids in breast milk and early weight gain in breast-fed infants
    Salome Scholtens
    Institute for Risk Assessment Sciences, Utrecht University, The Netherlands
    Br J Nutr 101:116-21. 2009
    ..The n-3 and n-6 LCPUFA content in breast milk did not affect weight or BMI gain in the first year of life in breast-fed term infants...
  51. doi request reprint Respiratory health effects of ultrafine and fine particle exposure in cyclists
    Maciej Strak
    Institute for Risk Assessment Sciences, Division of Environmental Epidemiology, Utrecht University, PO Box 80178, 3508 TD Utrecht, The Netherlands
    Occup Environ Med 67:118-24. 2010
    ..We carried out a study to investigate the acute respiratory health effects of air pollution related to commuting by bicycle...
  52. doi request reprint Air pollution exposure affects circulating white blood cell counts in healthy subjects: the role of particle composition, oxidative potential and gaseous pollutants - the RAPTES project
    Maaike Steenhof
    Division of Toxicology and Division of Environmental Epidemiology, Institute for Risk Assessment Sciences IRAS, Utrecht University, Utrecht, The Netherlands
    Inhal Toxicol 26:141-65. 2014
    ..Future studies should indicate if air pollution exposure-induced changes in blood cell counts results in adverse cardiovascular effects in susceptible individuals. ..
  53. ncbi request reprint Long-term personal exposure to traffic-related air pollution among school children, a validation study
    Sofie van Roosbroeck
    Institute for Risk Assessment Sciences, Utrecht University, P O Box 80176, 3508 TD Utrecht, The Netherlands
    Sci Total Environ 368:565-73. 2006
    ..This finding supports the use of 'living near a busy road' as a measure of exposure in epidemiological studies on the effects of traffic-related air pollution in children...
  54. doi request reprint Stability of measured and modelled spatial contrasts in NO(2) over time
    Marloes Eeftens
    Institute for Risk Assessment Sciences IRAS, Utrecht University, PO Box 80178, 3508 TD Utrecht, The Netherlands
    Occup Environ Med 68:765-70. 2011
    ..We tested the stability of measured and modelled spatial contrasts in outdoor nitrogen dioxide (NO(2)) pollution across the Netherlands over 8 years...
  55. doi request reprint Traffic-related air pollution and pregnancy outcomes in the Dutch ABCD birth cohort study
    Ulrike Gehring
    Institute for Risk Assessment Sciences, Utrecht University, 3508 TD Utrecht, The Netherlands
    Occup Environ Med 68:36-43. 2011
    ..As European data on this topic are limited, the aim of this study was to evaluate the impact of maternal exposure to traffic-related air pollution during different periods of pregnancy on preterm birth and fetal growth...
  56. doi request reprint Air pollution and exhaled nitric oxide in Dutch schoolchildren
    Haitske Graveland
    Institute for Risk Assessment Sciences, Utrecht University, Utrecht, The Netherlands
    Occup Environ Med 68:551-6. 2011
    ..No studies have simultaneously addressed the long-term and short-term associations between traffic-related air pollution and exhaled NO...
  57. ncbi request reprint Breastfeeding, weight gain in infancy, and overweight at seven years of age: the prevention and incidence of asthma and mite allergy birth cohort study
    Salome Scholtens
    Institute for Risk Assessment Sciences, Utrecht University, Utrecht, The Netherlands
    Am J Epidemiol 165:919-26. 2007
    ..These findings suggest that the lower BMI and lower risk of overweight among breastfed children later in life are already achieved at 1 year of age...
  58. doi request reprint Time in bed, sleep quality and associations with cardiometabolic markers in children: the Prevention and Incidence of Asthma and Mite Allergy birth cohort study
    Nina E Berentzen
    Center for Nutrition, Prevention, and Health Services, National Institute for Public Health and the Environment, Bilthoven, The Netherlands Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands
    J Sleep Res 23:3-12. 2014
    ..Therefore, we consider it premature to propose that improved sleep could reduce cardiovascular risk during childhood. ..
  59. pmc Evaluation of a low-cost electrostatic dust fall collector for indoor air endotoxin exposure assessment
    Ilka Noss
    Institute for Risk Assessment Sciences, Utrecht University, Utrecht, The Netherlands
    Appl Environ Microbiol 74:5621-7. 2008
    ..We therefore conclude that measuring endotoxin levels with the EDC is a valid measure of average airborne endotoxin exposure, while reproducibility over time is at least equivalent to that of reservoir dust analyses...
  60. doi request reprint Development of Land Use Regression models for PM(2.5), PM(2.5) absorbance, PM(10) and PM(coarse) in 20 European study areas; results of the ESCAPE project
    Marloes Eeftens
    Institute for Risk Assessment Sciences, Utrecht University, P O Box 80178, 3508 TD Utrecht, The Netherlands
    Environ Sci Technol 46:11195-205. 2012
    ..The final LUR models are used to estimate air pollution concentrations at the home addresses of participants in the health studies involved in ESCAPE...
  61. pmc Composition of PM affects acute vascular inflammatory and coagulative markers - the RAPTES project
    Maciej Strak
    Centre for Environmental Health MGO, National Institute for Public Health and the Environment RIVM, Bilthoven, The Netherlands
    PLoS ONE 8:e58944. 2013
    ..Exposure to ambient particulate matter (PM) has been associated with adverse cardiovascular effects in epidemiological studies. Current knowledge of independent effects of individual PM characteristics remains limited...
  62. ncbi request reprint Stakeholder needs for air pollution and health information
    Eric Gordon Sanderson
    Institute for Risk Assessment Sciences, University of Utrecht, Utrecht, The Netherlands
    J Toxicol Environ Health A 69:1819-25. 2006
    ....
  63. ncbi request reprint Estimating long-term average particulate air pollution concentrations: application of traffic indicators and geographic information systems
    Michael Brauer
    Utrecht University, Institute for Risk Assessment Sciences, Environmental and Occupational Health Group, Utrecht, The Netherlands
    Epidemiology 14:228-39. 2003
    ....
  64. ncbi request reprint Validity of residential traffic intensity as an estimate of long-term personal exposure to traffic-related air pollution among adults
    Sofie van Roosbroeck
    Division Environmental Epidemiology, Institute for Risk Assessment Sciences, Utrecht University, P O Box 801 78, 3508 TD Utrecht, The Netherlands
    Environ Sci Technol 42:1337-44. 2008
    ..Time spent in traffic and spending time outdoors were associated with increased personal exposure of soot and PM2.5, but not NOx...
  65. pmc In vitro toxicity of particulate matter (PM) collected at different sites in the Netherlands is associated with PM composition, size fraction and oxidative potential--the RAPTES project
    Maaike Steenhof
    Division of Toxicology, Institute for Risk Assessment Sciences, Utrecht University, PO Box 80177, 3508 TD Utrecht, The Netherlands
    Part Fibre Toxicol 8:26. 2011
    ..This study investigated the in vitro toxicity of ambient PM collected at different sites in the Netherlands in relation to PM composition and oxidative potential...
  66. doi request reprint Evaluation of land use regression models for NO2 and particulate matter in 20 European study areas: the ESCAPE project
    Meng Wang
    Institute for Risk Assessment Sciences, Utrecht University, P O Box 80178, 3508 TD Utrecht, The Netherlands
    Environ Sci Technol 47:4357-64. 2013
    ..Nevertheless, in most areas LUR models still explained a substantial fraction of the variation of concentrations measured at independent sites...
  67. pmc What drives prescribing of asthma medication to children? A multilevel population-based study
    Mira G P Zuidgeest
    Division of Pharmacoepidemiology and Pharmacotherapy, Utrecht Institute for Pharmaceutical Sciences UIPS, Faculty of Science, Utrecht University, Utrecht, The Netherlands
    Ann Fam Med 7:32-40. 2009
    ..This challenge creates an opportunity for variability in prescribing. The aim of our study was to investigate how and to what degree patient, family, and physician characteristics influence prescribing of asthma medication in children...
  68. doi request reprint The impact of ambient NO on online measurements of exhaled and nasal NO: the PIAMA study
    Ulrike Gehring
    Institute for Risk Assessment Sciences, Utrecht University, Utrecht, The Netherlands
    Pediatr Allergy Immunol 20:665-72. 2009
    ..The currently recommended technique including inhalation through an NO scrubber effectively deals with variable levels of ambient NO on FENO. In contrast, ambient NO has an effect on measurements of nNO...
  69. doi request reprint Neonatal total IgE and respiratory tract infections in children with intrauterine smoke exposure
    Jopje Ruskamp
    Department of Paediatrics, Wilhelmina Children s Hospital, University Medical Centre Utrecht, Utrecht, The Netherlands
    Arch Dis Child 95:427-31. 2010
    ..We examined whether early atopic status (defined by elevated neonatal total IgE (tIgE) or symptoms of atopic dermatitis) modified the association between ETS exposure and RTI...
  70. doi request reprint Polymorphisms in the mannan-binding lectin gene are not associated with questionnaire-reported respiratory tract infections in children
    Jopje M Ruskamp
    Department of Pediatrics, Wilhelmina Children s Hospital, University Medical Center Utrecht, University of Utrecht, Lundlaan 6, Utrecht, The Netherlands
    J Infect Dis 198:1707-13. 2008
    ..Large-scale replication of previous associations is needed, however. We investigated the association between MBL2 polymorphisms and the frequency of RTI in a large population-based birth cohort of white children...
  71. ncbi request reprint Association between mortality and indicators of traffic-related air pollution in the Netherlands: a cohort study
    Gerard Hoek
    Institute for Risk Assessment Sciences, Environmental and Occupational Health Group, Utrecht University, Utrecht, Netherlands
    Lancet 360:1203-9. 2002
    ..We aimed to assess the relation between traffic-related air pollution and mortality in participants of the Netherlands Cohort study on Diet and Cancer (NLCS), an ongoing study...
  72. pmc Mite and pet allergen levels in homes of children born to allergic and nonallergic parents: the PIAMA study
    Rob T van Strien
    Department of Environmental and Occupational Health, Institute for Risk Assessment Sciences, Utrecht University, Utrecht, The Netherlands
    Environ Health Perspect 110:A693-8. 2002
    ..Parental mattresses in homes of allergic mothers had lower cat and mite (but not dog) allergen loadings than mattresses in homes of nonallergic parents. Paternal (as opposed to maternal) allergy seemed to have little influence...
  73. doi request reprint Inverse association between endotoxin exposure and canine atopic dermatitis
    Frank A Looringh van Beeck
    Department of Infectious Diseases and Immunology, Utrecht University, Utrecht, The Netherlands
    Vet J 190:215-9. 2011
    ..The results indicated that endotoxin exposure is inversely associated with CAD, suggesting a protective effect of high indoor endotoxin exposure towards the development of the condition...
  74. ncbi request reprint Reported versus measured body weight and height of 4-year-old children and the prevalence of overweight
    Salome Scholtens
    Institute for Risk Assessment Sciences IRAS, Utrecht University, Utrecht, The Netherlands
    Eur J Public Health 17:369-74. 2007
    ..In addition, we studied the determinants and the consequences of differences between reported and measured data...
  75. pmc Use of passive diffusion sampling method for defining NO2 concentrations gradient in São Paulo, Brazil
    Agnes Soares da Silva
    Institute for Risk Assessment Sciences IRAS, Utrecht University, Yalelaan 2, 3508 TD, Utrecht, The Netherlands
    Environ Health 5:19. 2006
    ..This study was intended to identify a gradient of exposure to traffic-related air pollution within different areas in São Paulo to provide information for future epidemiological studies...
  76. ncbi request reprint A critique of "fine particulate air pollution and total mortality among elderly Californians, 1973-2002" by James E. Enstrom
    Bert Brunekreef
    Institute for Risk Assessment Sciences, Universiteit Utrecht, Utrecht, The Netherlands
    Inhal Toxicol 18:507-8; discussuin 509-14. 2006
  77. ncbi request reprint Air pollution and health
    Bert Brunekreef
    Institute for Risk Assessment Sciences, Utrecht University, PO Box 80176, 3508 TD, Utrecht, Netherlands
    Lancet 360:1233-42. 2002
    ..In this review, we discuss the evidence for adverse effects on health of selected air pollutants...
  78. doi request reprint Concentration response functions for ultrafine particles and all-cause mortality and hospital admissions: results of a European expert panel elicitation
    Gerard Hoek
    Institute for Risk Assessment Sciences and Copernicus Institute, University of Utrecht, Utrecht, The Netherlands
    Environ Sci Technol 44:476-82. 2010
    ..This expert elicitation provides the first quantitative evaluation of estimates of concentration response functions between urban air ultrafine particles and all-cause mortality and hospital admissions...
  79. pmc Associations between PM2.5 and heart rate variability are modified by particle composition and beta-blocker use in patients with coronary heart disease
    Jeroen J de Hartog
    Institute for Risk Assessment Sciences, Utrecht University, Utrecht, The Netherlands
    Environ Health Perspect 117:105-11. 2009
    ..Previously we reported heterogeneous associations between particulate matter with aerodynamic diameter < 2.5 microm (PM2.5) and HRV across three study centers...
  80. doi request reprint Respiratory effects of commuters' exposure to air pollution in traffic
    Moniek Zuurbier
    Environment Health Department, Public Health Services Gelderland Midden, Arnhem, The Netherlands
    Epidemiology 22:219-27. 2011
    ..Controlled exposure studies have shown acute respiratory effects of short, high exposures to air pollution from motor vehicles. Acute health effects of lower real-life exposures in traffic are unclear...
  81. pmc Commuters' exposure to particulate matter air pollution is affected by mode of transport, fuel type, and route
    Moniek Zuurbier
    Public Health Services Gelderland Midden, Arnhem, The Netherlands
    Environ Health Perspect 118:783-9. 2010
    ..Commuters are exposed to high concentrations of air pollutants, but little quantitative information is currently available on differences in exposure between different modes of transport, routes, and fuel types...
  82. ncbi request reprint The brave new world of lives sacrificed and saved, deaths attributed and avoided
    Bert Brunekreef
    Institute for Risk Assessment Sciences and Julius Center for Health Sciences and Primary Care, Utrecht University, Utrecht, The Netherlands
    Epidemiology 18:785-8. 2007
    ....
  83. pmc Meeting report: national workshops for the communication of air pollution and health information: summary of four workshops in different regions of Europe
    Eric Gordon Sanderson
    Institute for Risk Assessment Sciences, Universiteit Utrecht, Utrecht, The Netherlands
    Environ Health Perspect 114:1108-12. 2006
    ..Because a broad stakeholder involvement in decision making can positively affect the development of widely supported policies, such meetings should be continued for Europe and elsewhere...
  84. ncbi request reprint Design of cohort studies for air pollution health effects
    Bert Brunekreef
    Institute for Risk Assessment Sciences, University of Utrecht, Utrecht, The Netherlands
    J Toxicol Environ Health A 66:1723-9. 2003
    ..In addition, following the examples of Sweden, the Netherlands, and Germany, the use of geographical information systems is recommended to assess exposure to air pollutants at the address rather than the community level...
  85. ncbi request reprint After the wall
    Bert Brunekreef
    Institute for Risk Assessment Sciences, Utrecht University, PO Box 80176, 3508 TD Utrecht, The Netherlands
    Epidemiology 13:376-8. 2002
  86. ncbi request reprint Performance of different exposure assessment approaches in a study of bitumen fume exposure and lung cancer mortality
    Igor Burstyn
    Institute for Risk Assessment Sciences, Utrecht University, Utrecht, The Netherlands
    Am J Ind Med 43:40-8. 2003
    ..We compared performance of different exposure assessment approaches in a cohort study of cancer risk among European asphalt workers...
  87. doi request reprint Endotoxin levels in cow's milk samples from farming and non-farming families - the PASTURE study
    Ulrike Gehring
    Utrecht University, Institute for Risk Assessment Sciences, Utrecht, The Netherlands
    Environ Int 34:1132-6. 2008
    ..Children from farming families have less allergies than their peers. Consumption of farm milk or unpasteurized milk has been shown to explain (part of) the farming effect or protect against allergies independent of farming status...
  88. ncbi request reprint He who pays the piper, calls the tune
    Bert Brunekreef
    University of Utrecht Institute for Risk Assessment Sciences, University of Utrecht, Utrecht, The Netherlands
    Epidemiology 17:246-7. 2006
  89. ncbi request reprint Commentary: health review committee
    Millicent Higgins
    J Toxicol Environ Health A 66:1655-87; discussion 1715-22. 2003
  90. ncbi request reprint Fatty acids in breast milk of allergic and non-allergic mothers: The PIAMA birth cohort study
    Alet Wijga
    National Institute of Public Health and the Environment, Bilthoven, The Netherlands
    Pediatr Allergy Immunol 14:156-62. 2003
    ....
  91. ncbi request reprint Not all farming environments protect against the development of asthma and wheeze in children
    Markus Johannes Ege
    University Children s Hospital Munich, Germany
    J Allergy Clin Immunol 119:1140-7. 2007
    ..Inconsistent data on the relation of farming to asthma and wheeze have raised some doubt about a true protective effect...
  92. ncbi request reprint Estimation of outdoor NO(x), NO(2), and BTEX exposure in a cohort of pregnant women using land use regression modeling
    Inmaculada Aguilera
    Centre for Research in Environmental Epidemiology, Institut Municipal Investigacio Medica, Doctor Aiguader 88, 08003 Barcelona, Spain
    Environ Sci Technol 42:815-21. 2008
    ..These models will be used to study the association between prenatal exposure to air pollution and adverse pregnancy outcomes and early childhhod effects in the cohort...
  93. ncbi request reprint Atopic sensitization and the international variation of asthma symptom prevalence in children
    Gudrun Weinmayr
    Institute of Epidemiology, Ulm University, Helmholtzstrasse 22, D 89075 Ulm, Germany
    Am J Respir Crit Care Med 176:565-74. 2007
    ..Atopic sensitization has long been known to be related to asthma in children, but its role in determining asthma prevalence remains to be elucidated further...
  94. ncbi request reprint Air pollution from traffic and the development of respiratory infections and asthmatic and allergic symptoms in children
    Michael Brauer
    School of Occupational and Environmental Hygiene, University of British Columbia, Vancouver, British Columbia, Canada
    Am J Respir Crit Care Med 166:1092-8. 2002
    ..These findings are subject to confirmation at older ages, when asthma can be more readily diagnosed...
  95. ncbi request reprint Particulate air pollution and risk of ST-segment depression during repeated submaximal exercise tests among subjects with coronary heart disease: the Exposure and Risk Assessment for Fine and Ultrafine Particles in Ambient Air (ULTRA) study
    Juha Pekkanen
    Unit of Environmental Epidemiology, National Public Health Institute, Kuopio, Finland
    Circulation 106:933-8. 2002
    ..We therefore assessed the associations between levels of the 3 main modes of urban aerosol distribution and the occurrence of ST-segment depressions during repeated exercise tests...
  96. ncbi request reprint Placebo-controlled trial of house dust mite-impermeable mattress covers: effect on symptoms in early childhood
    Laurens P Koopman
    Department of Pediatrics, Erasmus University Medical Center Sophia Children s Hospital, 3000 CB Rotterdam, The Netherlands
    Am J Respir Crit Care Med 166:307-13. 2002
    ..Follow-up will determine the long-term effect of the intervention on the development of atopic disease...
  97. ncbi request reprint Toxicity of coarse and fine particulate matter from sites with contrasting traffic profiles
    Miriam E Gerlofs-Nijland
    National Institute for Public Health and the Environment, Bilthoven, The Netherlands
    Inhal Toxicol 19:1055-69. 2007
    ..It is likely that the toxicological responses of SH rats were associated with specific PM components derived from brake wear (copper and barium), tire wear (zinc), and wood smoke (potassium)...
  98. ncbi request reprint Residential outdoor air pollution and lung function in schoolchildren
    Bente Oftedal
    Division of Epidemiology, Norwegian Institute of Public Health, Oslo, Norway
    Epidemiology 19:129-37. 2008
    ..We investigated the associations with lung function of residential outdoor air pollution in early life, total lifetime, and days before lung function test...
  99. doi request reprint Panel discussion review: session two--interpretation of observed associations between multiple ambient air pollutants and health effects in epidemiologic analyses
    Jee Young Kim
    National Center for Environmental Assessment, US Environmental Protection Agency, Research Triangle Park, NC 27711, USA
    J Expo Sci Environ Epidemiol 17:S83-9. 2007
    ..Source apportionment analysis is one method that may allow further advancement in understanding the source components that contribute to multipollutant health effects...
  100. ncbi request reprint Spatial variation in nitrogen dioxide in three European areas
    Marie Lewne
    Occupational and Environmental Health, Norrbacka, SE 171 76 Stockholm, Sweden
    Sci Total Environ 332:217-30. 2004
    ..The spatial variation was substantially larger for NO2 than the variation for PM2.5 and similar to PM2.5 absorbance, measured in the same locations...
  101. ncbi request reprint The effect of prenatal exposure on total IgE at birth and sensitization at twelve months and four years of age: The PIAMA study
    Marjan Kerkhof
    Department of Epidemiology, University of Groningen, Groningen, The Netherlands
    Pediatr Allergy Immunol 16:10-8. 2005
    ..Our results suggest a short-lasting protective effect of prenatal exposure to pets on total IgE at birth and early sensitization...