- Genomic and biochemical analysis of N glycosylation in the mushroom-forming basidiomycete Schizophyllum communeElsa Berends
Molecular Microbiology and Kluyver Centre for Genomics of Industrial Fermentations, Institute of Biomembranes, Utrecht University, The Netherlands
Appl Environ Microbiol 75:4648-52. 2009..N-linked glycans in vegetative mycelium and fruiting bodies of S. commune are mainly Man(7)GlcNAc(2) and Man(5)GlcNAc(2), respectively, suggesting more efficient mannose trimming in the mushroom...
- The use of mushroom-forming fungi for the production of N-glycosylated therapeutic proteinsElsa Berends
Molecular Microbiology and Kluyver Center for Genomics of Industrial Fermentations, Institute of Biomembranes, Utrecht University, Padualaan 8, 3584 CH Utrecht, The Netherlands
Trends Microbiol 17:439-43. 2009..This requires cost-effective production platforms that display correct and homogeneous N-glycosylation. Based on recent results, we propose to use mushroom-forming basidiomycetes for the production of N-glycosylated therapeutic proteins...
- Identification of alg3 in the mushroom-forming fungus Schizophyllum commune and analysis of the Δalg3 knockout mutantElsa Berends
Microbiology and Kluyver Centre for Genomics of Industrial Fermentations, Utrecht University, Utrecht, The Netherlands
Glycobiology 23:147-54. 2013..This provides a first step toward engineering of a homogeneous, humanized N-glycosylation pattern for the production of therapeutic glycoproteins in mushrooms...