Research Topics
| Lex WunderinkSummaryAffiliation: University Medical Center Groningen Country: The Netherlands Publications
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Detail Information
Publications
Guided discontinuation versus maintenance treatment in remitted first-episode psychosis: relapse rates and functional outcomeLex Wunderink
University Medical Center Groningen, University of Groningen, Department of Psychiatry, Groningen, The Netherlands
J Clin Psychiatry 68:654-61. 2007..To compare the consequences of a guided discontinuation strategy and maintenance treatment in remitted first-episode psychosis in terms of relapse rates and functional outcome...
Treatment delay and response rate in first episode psychosisA Wunderink
Department of Psychiatry, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
Acta Psychiatr Scand 113:332-9. 2006..There is no consistent evidence of long duration of untreated psychosis (DUP) predicting long time to response (TTR) in first psychosis. This study aims to investigate the predictors of DUP and TTR in a first episode patient population...
Predictive validity of proposed remission criteria in first-episode schizophrenic patients responding to antipsychoticsLex Wunderink
Department of Psychiatry, University Medical Center Groningen, University of Groningen, PO Box 30 001, 9700 R B Groningen, The Netherlands
Schizophr Bull 33:792-6. 2007..The criteria represent a practicable benchmark with clinical relevance. Their implementation should be promoted in research settings, clinical practice, and routine outcome assessment procedures...
Clinical recovery in first-episode psychosisLex Wunderink
University Medical Center Groningen, University Psychiatric Center 5 21, University of Groningen, 9700 RB Groningen, The Netherlands
Schizophr Bull 35:362-9. 2009..The aim of this study is to explore clinical recovery in first-episode patients, defined by meeting criteria for both symptomatic and functional remission...
Association of genetic variants of the histamine H1 and muscarinic M3 receptors with BMI and HbA1c values in patients on antipsychotic medicationJelle Vehof
Department of Psychiatry, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
Psychopharmacology (Berl) 216:257-65. 2011..Antipsychotic affinity for the histamine H1 receptor and the muscarinic M3 receptor have been associated with the side effects weight gain, and development of diabetes, respectively...
Duration of untreated psychosis and negative symptoms - A systematic review and meta-analysis of individual patient dataNynke Boonstra
Friesland Mental Health Care Service, Department of Education and Research, Leeuwarden, The Netherlands University Medical Center Groningen, Department of Psychiatry, University of Groningen, Groningen, The Netherlands NHL University of Applied Science, Institute of Healthcare and Welfare Studies, Leeuwarden, The Netherlands Electronic address
Schizophr Res 142:12-9. 2012..Longer duration of untreated psychosis (DUP) is associated with poorer outcome in terms of positive symptoms, relapse rate, and time to remission. In contrast, the association with negative symptoms is less consistent...
Improving detection of first-episode psychosis by mental health-care services using a self-report questionnaireNynke Boonstra
Friesland Mental Health Services, Department of Education and Research, Leeuwarden, The Netherlands
Early Interv Psychiatry 3:289-95. 2009..To examine the utility of the Community Assessment of Psychic Experiences (CAPE)-42, a self-report questionnaire, to improve detection of first-episode psychosis in new referrals to mental health services...
Effects of bilateral repetitive transcranial magnetic stimulation on treatment resistant auditory-verbal hallucinations in schizophrenia: a randomized controlled trialAns Vercammen
Department of Neuroscience, University Medical Center Groningen and BCN NeuroImaging Center, University of Groningen, The Netherlands
Schizophr Res 114:172-9. 2009..This study aimed to investigate whether 1 Hz repetitive transcranial magnetic stimulation (rTMS) of the bilateral temporo-parietal region would lead to increased effectiveness in the management of AVH, compared to left rTMS or placebo...
[Assertive community treatment in psychiatry: less drop-out from mental health care]Sjoerd Sytema
Universitair Medisch Centrum Groningen, afd Universitair Centrum Psychiatrie, Groningen, The Netherlands
Ned Tijdschr Geneeskd 154:A1692. 2010..With assertive community treatment, drop-out is averted for most patients. We consider this to be an important positive result...
