Victorien M Wolters
Affiliation: University Medical Center Utrecht
Country: The Netherlands
- Is gluten challenge really necessary for the diagnosis of coeliac disease in children younger than age 2 years?Victorien M Wolters
Department of Paediatric Gastroenterology, University Medical Centre Utrecht, P O Box 85090, Utrecht 3508 AB, The Netherlands
J Pediatr Gastroenterol Nutr 48:566-70. 2009..In the diagnosis of coeliac disease (CD), gluten challenge is recommended for children under the age of 2 years at initial biopsy. The aim of the study was to investigate the diagnostic yield of gluten challenge in this group of children...
- Intestinal barrier gene variants may not explain the increased levels of antigliadin antibodies, suggesting other mechanisms than altered permeabilityVictorien M Wolters
Department of Pediatric Gastroenterology, UMC Utrecht, Utrecht, The Netherlands
Hum Immunol 71:392-6. 2010..Thus, other immunologic phenomena play a role in the increased prevalence of elevated AGA in patients with Down syndrome, possibly involving altered induction and/or maintenance of tolerance...
- Tissue transglutaminase levels above 100 U/mL and celiac disease: a prospective studyAmani Mubarak
Department of Pediatric Gastroenterology, Wilhelmina Children s Hospital, University Medical Center Utrecht, 3508 AB Utrecht, The Netherlands
World J Gastroenterol 18:4399-403. 2012..To investigate whether a tissue-transglutaminase antibody (tTGA) level ≥ 100 U/mL is sufficient for the diagnosis of celiac disease (CD)...
- The MYO9B gene is a strong risk factor for developing refractory celiac diseaseVictorien M Wolters
Department of Pediatric Gastroenterology, University Medical Centre Utrecht, Utrecht, The Netherlands
Clin Gastroenterol Hepatol 5:1399-405, 1405.e1-2. 2007..HLA-DQ2 homozygosity is associated with complications of CD such as refractory celiac disease type II (RCD II) and enteropathy-associated T-cell lymphoma (EATL). We investigated whether MYO9B also predisposes to RCD II and EATL...
- A biopsy is not always necessary to diagnose celiac diseaseAmani Mubarak
Department of Pediatric Gastroenterology, University Medical Center Utrecht, The Netherlands
J Pediatr Gastroenterol Nutr 52:554-7. 2011..This raises the question of whether a small intestinal biopsy is always necessary. The aim of the present study was, therefore, to investigate whether a small intestinal biopsy can be avoided in a selected group of patients...
- Genetic background of celiac disease and its clinical implicationsVictorien M Wolters
Department of Pediatric Gastroenterology, University Medical Center, Utrecht, The Netherlands
Am J Gastroenterol 103:190-5. 2008..Genetic risk profiles for CD would be helpful in clinical practice for predicting disease susceptibility and progression...