John H J Wokke

Summary

Affiliation: University Medical Center Utrecht
Country: The Netherlands

Publications

  1. ncbi Quantification of SMN protein in leucocytes from spinal muscular atrophy patients: effects of treatment with valproic acid
    Sanne Piepers
    Rudolf Magnus Institute of Neuroscience, Department of Neurology, University Medical Centre Utrecht, The Netherlands
    J Neurol Neurosurg Psychiatry 82:850-2. 2011
  2. ncbi Fatigue is part of the burden of neuromuscular diseases
    John H J Wokke
    J Neurol 254:948-9. 2007
  3. ncbi Weighted gene co-expression network analysis of the peripheral blood from Amyotrophic Lateral Sclerosis patients
    Christiaan G J Saris
    Department of Neurology, Rudolf Magnus Institute of Neuroscience, University Medical Center Utrecht, Utrecht 3584 CX, The Netherlands
    BMC Genomics 10:405. 2009
  4. ncbi Clinical features of late-onset Pompe disease: a prospective cohort study
    John H J Wokke
    Universitair Medisch Centrum Utrecht HP G03 228, Heidelberglaan 100, 3584 CX Utrecht, Netherlands
    Muscle Nerve 38:1236-45. 2008
  5. ncbi Effect of non-invasive ventilation on survival, quality of life, respiratory function and cognition: a review of the literature
    Sanne Piepers
    Department of Neurology, Rudolph Magnus Institute of Neuroscience, University Medical Centre Utrecht, Utrecht, The Netherlands
    Amyotroph Lateral Scler 7:195-200. 2006
  6. ncbi Magnesium treatment for patients with refractory status epilepticus due to POLG1-mutations
    Nora A Visser
    Rudolf Magnus Institute of Neuroscience, Department of Neurology, University Medical Centre Utrecht, PO Box 85500, 3508 GA, Utrecht, The Netherlands
    J Neurol 258:218-22. 2011
  7. ncbi Is cold paresis related to axonal depolarization?
    Hessel Franssen
    Department of Neurology, Neuromuscular Disease Group, Rudolf Magnus Institute for Neuroscience, University Medical Center Utrecht, The Netherlands
    J Peripher Nerv Syst 15:227-37. 2010
  8. ncbi Severity of Guillain-Barré syndrome is associated with Fc gamma Receptor III polymorphisms
    Nina M van Sorge
    Department of Neurology G03 228, University Medical Center Utrecht, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands
    J Neuroimmunol 162:157-64. 2005

Collaborators

Detail Information

Publications8

  1. ncbi Quantification of SMN protein in leucocytes from spinal muscular atrophy patients: effects of treatment with valproic acid
    Sanne Piepers
    Rudolf Magnus Institute of Neuroscience, Department of Neurology, University Medical Centre Utrecht, The Netherlands
    J Neurol Neurosurg Psychiatry 82:850-2. 2011
    ..Increasing SMN protein production by histone deacetylase inhibiting drugs such as valproic acid (VPA) is an experimental treatment strategy for SMA...
  2. ncbi Fatigue is part of the burden of neuromuscular diseases
    John H J Wokke
    J Neurol 254:948-9. 2007
  3. ncbi Weighted gene co-expression network analysis of the peripheral blood from Amyotrophic Lateral Sclerosis patients
    Christiaan G J Saris
    Department of Neurology, Rudolf Magnus Institute of Neuroscience, University Medical Center Utrecht, Utrecht 3584 CX, The Netherlands
    BMC Genomics 10:405. 2009
    ..Since access to spinal cord tissue is not possible at disease onset, we investigated changes in gene expression profiles in whole blood of ALS patients...
  4. ncbi Clinical features of late-onset Pompe disease: a prospective cohort study
    John H J Wokke
    Universitair Medisch Centrum Utrecht HP G03 228, Heidelberglaan 100, 3584 CX Utrecht, Netherlands
    Muscle Nerve 38:1236-45. 2008
    ..The outcome measures were demonstrated to be safe and reliable. Symptom duration was identified as the best predictor of the extent of skeletal and respiratory muscle weakness...
  5. ncbi Effect of non-invasive ventilation on survival, quality of life, respiratory function and cognition: a review of the literature
    Sanne Piepers
    Department of Neurology, Rudolph Magnus Institute of Neuroscience, University Medical Centre Utrecht, Utrecht, The Netherlands
    Amyotroph Lateral Scler 7:195-200. 2006
    ..All studies suggest a beneficial effect on QoL and other outcome measures (Evidence level Class II-III). Well-designed randomized controlled trials comparing the effect on QoL and survival have not been performed...
  6. ncbi Magnesium treatment for patients with refractory status epilepticus due to POLG1-mutations
    Nora A Visser
    Rudolf Magnus Institute of Neuroscience, Department of Neurology, University Medical Centre Utrecht, PO Box 85500, 3508 GA, Utrecht, The Netherlands
    J Neurol 258:218-22. 2011
    ..Given the difficulties encountered while treating epilepsy in patients with this syndrome, magnesium therapy might be considered...
  7. ncbi Is cold paresis related to axonal depolarization?
    Hessel Franssen
    Department of Neurology, Neuromuscular Disease Group, Rudolf Magnus Institute for Neuroscience, University Medical Center Utrecht, The Netherlands
    J Peripher Nerv Syst 15:227-37. 2010
    ..The induced weakness may be explained not only by this mechanism but also by impaired muscle contraction...
  8. ncbi Severity of Guillain-Barré syndrome is associated with Fc gamma Receptor III polymorphisms
    Nina M van Sorge
    Department of Neurology G03 228, University Medical Center Utrecht, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands
    J Neuroimmunol 162:157-64. 2005
    ..Results suggest that Fc gammaRIII genotypes may represent mild disease-modifying factors in GBS...