John H J Wokke

Summary

Affiliation: University Medical Center Utrecht
Country: The Netherlands

Publications

  1. doi request reprint Quantification of SMN protein in leucocytes from spinal muscular atrophy patients: effects of treatment with valproic acid
    Sanne Piepers
    Rudolf Magnus Institute of Neuroscience, Department of Neurology, University Medical Centre Utrecht, The Netherlands
    J Neurol Neurosurg Psychiatry 82:850-2. 2011
  2. pmc Clinical features and predictors for disease natural progression in adults with Pompe disease: a nationwide prospective observational study
    Nadine A M E van der Beek
    Department of Neurology, Center for Lysosomal and Metabolic Diseases, Erasmus MC University Medical Center, s Gravendijkwal 230, 3015 CE, Rotterdam, The Netherlands
    Orphanet J Rare Dis 7:88. 2012
  3. pmc Effect of enzyme therapy and prognostic factors in 69 adults with Pompe disease: an open-label single-center study
    Juna M de Vries
    Department of Neurology and Center for Lysosomal and Metabolic Diseases, Erasmus MC University Medical Center, Rotterdam, The Netherlands
    Orphanet J Rare Dis 7:73. 2012
  4. pmc Fatigue is part of the burden of neuromuscular diseases
    John H J Wokke
    J Neurol 254:948-9. 2007
  5. pmc Weighted gene co-expression network analysis of the peripheral blood from Amyotrophic Lateral Sclerosis patients
    Christiaan G J Saris
    Department of Neurology, Rudolf Magnus Institute of Neuroscience, University Medical Center Utrecht, Utrecht 3584 CX, The Netherlands
    BMC Genomics 10:405. 2009
  6. doi request reprint Clinical features of late-onset Pompe disease: a prospective cohort study
    John H J Wokke
    Universitair Medisch Centrum Utrecht HP G03 228, Heidelberglaan 100, 3584 CX Utrecht, Netherlands
    Muscle Nerve 38:1236-45. 2008
  7. doi request reprint Is cold paresis related to axonal depolarization?
    Hessel Franssen
    Department of Neurology, Neuromuscular Disease Group, Rudolf Magnus Institute for Neuroscience, University Medical Center Utrecht, The Netherlands
    J Peripher Nerv Syst 15:227-37. 2010
  8. pmc Magnesium treatment for patients with refractory status epilepticus due to POLG1-mutations
    Nora A Visser
    Rudolf Magnus Institute of Neuroscience, Department of Neurology, University Medical Centre Utrecht, PO Box 85500, 3508 GA, Utrecht, The Netherlands
    J Neurol 258:218-22. 2011
  9. ncbi request reprint Effect of non-invasive ventilation on survival, quality of life, respiratory function and cognition: a review of the literature
    Sanne Piepers
    Department of Neurology, Rudolph Magnus Institute of Neuroscience, University Medical Centre Utrecht, Utrecht, The Netherlands
    Amyotroph Lateral Scler 7:195-200. 2006
  10. ncbi request reprint Severity of Guillain-Barré syndrome is associated with Fc gamma Receptor III polymorphisms
    Nina M van Sorge
    Department of Neurology G03 228, University Medical Center Utrecht, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands
    J Neuroimmunol 162:157-64. 2005

Collaborators

Detail Information

Publications10

  1. doi request reprint Quantification of SMN protein in leucocytes from spinal muscular atrophy patients: effects of treatment with valproic acid
    Sanne Piepers
    Rudolf Magnus Institute of Neuroscience, Department of Neurology, University Medical Centre Utrecht, The Netherlands
    J Neurol Neurosurg Psychiatry 82:850-2. 2011
    ..Increasing SMN protein production by histone deacetylase inhibiting drugs such as valproic acid (VPA) is an experimental treatment strategy for SMA...
  2. pmc Clinical features and predictors for disease natural progression in adults with Pompe disease: a nationwide prospective observational study
    Nadine A M E van der Beek
    Department of Neurology, Center for Lysosomal and Metabolic Diseases, Erasmus MC University Medical Center, s Gravendijkwal 230, 3015 CE, Rotterdam, The Netherlands
    Orphanet J Rare Dis 7:88. 2012
    ..Furthermore, we defined the natural disease course and identified prognostic factors for disease progression...
  3. pmc Effect of enzyme therapy and prognostic factors in 69 adults with Pompe disease: an open-label single-center study
    Juna M de Vries
    Department of Neurology and Center for Lysosomal and Metabolic Diseases, Erasmus MC University Medical Center, Rotterdam, The Netherlands
    Orphanet J Rare Dis 7:73. 2012
    ..We investigated whether it alters the course of disease, and also identified potential prognostic factors...
  4. pmc Fatigue is part of the burden of neuromuscular diseases
    John H J Wokke
    J Neurol 254:948-9. 2007
  5. pmc Weighted gene co-expression network analysis of the peripheral blood from Amyotrophic Lateral Sclerosis patients
    Christiaan G J Saris
    Department of Neurology, Rudolf Magnus Institute of Neuroscience, University Medical Center Utrecht, Utrecht 3584 CX, The Netherlands
    BMC Genomics 10:405. 2009
    ..Since access to spinal cord tissue is not possible at disease onset, we investigated changes in gene expression profiles in whole blood of ALS patients...
  6. doi request reprint Clinical features of late-onset Pompe disease: a prospective cohort study
    John H J Wokke
    Universitair Medisch Centrum Utrecht HP G03 228, Heidelberglaan 100, 3584 CX Utrecht, Netherlands
    Muscle Nerve 38:1236-45. 2008
    ..The outcome measures were demonstrated to be safe and reliable. Symptom duration was identified as the best predictor of the extent of skeletal and respiratory muscle weakness...
  7. doi request reprint Is cold paresis related to axonal depolarization?
    Hessel Franssen
    Department of Neurology, Neuromuscular Disease Group, Rudolf Magnus Institute for Neuroscience, University Medical Center Utrecht, The Netherlands
    J Peripher Nerv Syst 15:227-37. 2010
    ..The induced weakness may be explained not only by this mechanism but also by impaired muscle contraction...
  8. pmc Magnesium treatment for patients with refractory status epilepticus due to POLG1-mutations
    Nora A Visser
    Rudolf Magnus Institute of Neuroscience, Department of Neurology, University Medical Centre Utrecht, PO Box 85500, 3508 GA, Utrecht, The Netherlands
    J Neurol 258:218-22. 2011
    ..Given the difficulties encountered while treating epilepsy in patients with this syndrome, magnesium therapy might be considered...
  9. ncbi request reprint Effect of non-invasive ventilation on survival, quality of life, respiratory function and cognition: a review of the literature
    Sanne Piepers
    Department of Neurology, Rudolph Magnus Institute of Neuroscience, University Medical Centre Utrecht, Utrecht, The Netherlands
    Amyotroph Lateral Scler 7:195-200. 2006
    ..All studies suggest a beneficial effect on QoL and other outcome measures (Evidence level Class II-III). Well-designed randomized controlled trials comparing the effect on QoL and survival have not been performed...
  10. ncbi request reprint Severity of Guillain-Barré syndrome is associated with Fc gamma Receptor III polymorphisms
    Nina M van Sorge
    Department of Neurology G03 228, University Medical Center Utrecht, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands
    J Neuroimmunol 162:157-64. 2005
    ..Results suggest that Fc gammaRIII genotypes may represent mild disease-modifying factors in GBS...