Research Topics
| Hero P WitSummaryAffiliation: University of Groningen Country: The Netherlands Publications
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Detail Information
Publications
Cochlear hydrops analysis masking procedure results in patients with unilateral Ménière's diseaseCharlotte M Kingma
Department of Otolaryngology, University Medical Center Groningen, Groningen, The Netherlands
Otol Neurotol 31:1004-8. 2010..To investigate the usefulness of the cochlear hydrops analysis masking procedure (CHAMP) as an additional diagnostic test in patients with definite unilateral Ménière's disease...
Frequency response for electromotility of isolated outer hair cells of the guinea pigH P Wit
Department of Experimental Otolaryngology, University Hospital, Groningen, The Netherlands
Hear Res 98:165-8. 1996..Correspondingly, impulse responses show a single narrow peak roughly 50 microseconds wide and have the shape of the impulse response for a critically damped harmonic oscillator...
Dynamics of inner ear pressure release, measured with a double-barreled micropipette in the guinea pigH P Wit
Department of Otorhinolaryngology, University Hospital Groningen, The Netherlands
Hear Res 132:131-9. 1999..The obtained results could be fitted with a simple physical model, when it was assumed that inner ear pressure recovery is a non-linear process, governed by a pressure-dependent flow resistance and/or membrane compliance...
Measurement of the mechanical compliance of the endolymphatic compartments in the guinea pigH P Wit
Department of Otorhinolaryngology, University Hospital Groningen, P O Box 30 001, 9700 RB, Groningen, The Netherlands
Hear Res 145:82-90. 2000..With this model, a larger compliance was found for the second compartment (vestibular part of endolymphatic system) than for the first compartment, into which fluid was injected (scala media)...
Cochlear aqueduct flow resistance is not constant during evoked inner ear pressure change in the guinea pigHero P Wit
Department of Otorhinolaryngology, University Hospital Groningen, PO Box 30 001, 9700 RB Groningen, The Netherlands
Hear Res 175:190-9. 2003..The change of flow resistance during inner ear pressure variation can be explained by a permeability change of the cochlear aqueduct, caused by a change of structures filling the aqueduct and its entrance in scala tympani...
Evaluation of cochlear function in an acute endolymphatic hydrops model in the guinea pig by measuring low-level DPOAEsWillem L Valk
Department of Otorhinolaryngology, University Hospital Groningen, P O Box 30 001, 9700 RB Groningen, The Netherlands
Hear Res 192:47-56. 2004..However, the precise mechanism of cochlear function change caused by endolymph volume increase (hydrops) remains to be elucidated...
Evaluation of low-frequency biasing as a diagnostic tool in Menière patientsNanda J Hof-Duin
Department of Otorhinolaryngology Head and Neck Surgery, University Medical Center Groningen, Faculty of Medicine of University of Groningen, 9700 RB Groningen, The Netherlands
Hear Res 231:84-9. 2007..An explanation could be that with increasing hearing loss the gain of the cochlear amplifier decreases, leading to smaller modulation depths...
Direct measurement flow resistance of cochlear aqueduct in guinea pigsElisabeth O Laurens-Thalen
Department of Otorhinolaryngology, University Hospital Groningen, Groningen, The Netherlands
Acta Otolaryngol 124:670-4. 2004..In this study the flow resistance of the cochlear aqueduct was determined and its relation with inner ear pressure was studied...
Quantification of audiogram fine-structure as a function of hearing thresholdJ Wiebe Horst
Department of Otorhinolaryngology, University Hospital Groningen, PO Box 30 001, 9700 RB Groningen, The Netherlands
Hear Res 176:105-12. 2003..e. the more peaks the higher the average peak height. The summated peak height S(p)=N(p)H(p) showed a strong dependence on the hearing loss. In cases of strong fine-structure, S(p) reached values around 200 dB...
Wavelet analysis demonstrates no abnormality in contralateral suppression of otoacoustic emissions in tinnitus patientsLeontien I Geven
Department of Otorhinolaryngology Head and Neck Surgery, University Medical Center Groningen, P O Box 30 001, 9700 RB Groningen, The Netherlands
Hear Res 286:30-40. 2012..No significant difference in suppression was found between the tinnitus patients and the control group...
Hippocampal volume measurement in patients with Ménière's disease: a pilot studyNynke Van Cruijsen
Department of Otorhinolaryngology, University Medical Center Groningen, Groningen, The Netherlands
Acta Otolaryngol 127:1018-23. 2007..No signs of chronic stress as in hippocampal atrophy were present in patients with Ménière's disease...
Evaluation of the relation between audiometric and psychometric measures of hearing after tympanoplastyAstrid G W Korsten-Meijer
Department of Otorhinolaryngology, University Hospital Groningen, Groningen, The Netherlands
Eur Arch Otorhinolaryngol 263:256-62. 2006..In addition, even small residual hearing losses (less than 25 dB HL) still lead, on average, to (m)AIAD scores that are substantially lower than the scores for normally hearing subjects...
Analysis of cortisol and other stress-related hormones in patients with Ménière's diseaseNynke Van Cruijsen
Department of Otorhinolaryngology, University Medical Centre Groningen, Groningen, The Netherlands
Otol Neurotol 26:1214-9. 2005..To evaluate cortisol and catecholamine levels in patients with Ménière's disease...
Functional sex differences in human primary auditory cortexLiesbet Ruytjens
Department of Otorhinolaryngology, University Medical Center Groningen, Groningen, The Netherlands
Eur J Nucl Med Mol Imaging 34:2073-81. 2007..Regional cerebral blood flow (rCBF) was measured in 10 male and 10 female volunteers while listening to sounds (music or white noise) and during a baseline (no auditory stimulation)...
Intratympanic gentamicin therapy for control of vertigo in unilateral Menire's disease: a prospective, double-blind, randomized, placebo-controlled trialRolf J Postema
Department of Otorhinolaryngology, University Medical Center Groningen, Groningen, The Netherlands
Acta Otolaryngol 128:876-80. 2008..The treatment also reduces the severity of the perceived aural fullness...
Evoked otoacoustic emissions in patients with Ménière's diseaseEmile de Kleine
Department of Otorhinolaryngology, University Hospital Groningen, PO Box 30.001, 9700 RB Groningen, The Netherlands
Otol Neurotol 23:510-6. 2002..This was best observed by comparing emission amplitude with smallest hearing loss instead of mean hearing loss...
A model for the relation between stimulus frequency and spontaneous otoacoustic emissions in lizard papillaeHero P Wit
Department of Otorhinolaryngology Head and Neck Surgery, University of Groningen, University Medical Center Groningen, P O Box 30 001, 9700RB Groningen, The Netherlands
J Acoust Soc Am 132:3273-9. 2012..J. 95, 4622-4630 (2008)], well describes both the amplitude and phase characteristics of SFOAEs and the relation between SFOAEs and SOAEs...
Cochlear ultrastructure in two-phase endolymphatic hydrops in the guinea-pigErwin A Dunnebier
Department of Otorhinolaryngology, University Hospital Groningen, The Netherlands
Eur Arch Otorhinolaryngol 259:17-23. 2002..Our findings demonstrate changes that may be reversible due to the compromising effect of a single treatment, and irreversible changes due to interaction of both compromising factors. These findings support our two-phase concept...
Reliability and validity of the (modified) Amsterdam Inventory for Auditory Disability and HandicapAstrid G W Meijer
Department of Otorhinolaryngology, University Hospital Groningen, The Netherlands
Int J Audiol 42:220-6. 2003..Construct validity showed a high correlation between scores on the (m)AIAD and scores on the HDQ. Criterion validity showed a moderate but significant correlation between scores on the (m)AIAD and hearing thresholds in dB HL...
Does the endolymphatic sinus function as a one-way valve?Hero P Wit
Hear Res 224:115-6. 2007
Detection of intracochlear and intracranial pressure changes with otoacoustic emissions: a gerbil modelBéla Büki
Laboratory of Sensory Biophysics, School of Medicine, P O Box 38, 63001 Clermont Ferrand, France
Hear Res 167:180-91. 2002..A relatively minor contribution from the tensor tympani was observed, possibly in relation to the detection of ICoP-induced displacement of the ossicular chain by neuromuscular spindles...
