Willemijn A K M Windt

Summary

Affiliation: University Medical Center Groningen
Country: The Netherlands

Publications

  1. ncbi Renal targeting of captopril using captopril-lysozyme conjugate enhances its antiproteinuric effect in adriamycin-induced nephrosis
    Willemijn A K M Windt
    Department of Clinical Pharmacology, Groningen University, Antonius Deusinglaan 1, 9713 AV Groningen, The Netherlands
    J Renin Angiotensin Aldosterone Syst 5:197-202. 2004
  2. ncbi Therapeutic resistance to angiotensin converting enzyme (ACE) inhibition is related to pharmacodynamic and -kinetic factors in 5/6 nephrectomized rats
    Willemijn A K M Windt
    Department of Clinical Pharmacology, Groningen Institute for Drug Evaluation, University Medical Center Groningen, University of Groningen, The Netherlands
    Eur J Pharmacol 580:231-40. 2008
  3. ncbi Myocardial infarction does not further impair renal damage in 5/6 nephrectomized rats
    Willemijn A K M Windt
    Department of Clinical Pharmacology, University Medical Center Groningen, PO Box 196, NL 9700 AD, Groningen, The Netherlands
    Nephrol Dial Transplant 23:3103-10. 2008
  4. ncbi Renal damage after myocardial infarction is prevented by renin-angiotensin-aldosterone-system intervention
    Willemijn A K M Windt
    Department of Clinical Pharmacology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
    J Am Soc Nephrol 17:3059-66. 2006
  5. ncbi Early, but not late therapy with a vasopressin V1a-antagonist ameliorates the development of renal damage after 5/6 nephrectomy
    Willemijn A K M Windt
    Department of Clinical Pharmacology, Groningen Institute for Drug Evaluation GUIDE, University Medical Center Groningen, Antonius Deusinglaan 1 NL 9713 AV Groningen NL 9713, The Netherlands
    J Renin Angiotensin Aldosterone Syst 7:217-24. 2006
  6. ncbi Myocardial infarction enhances progressive renal damage in an experimental model for cardio-renal interaction
    Richard P E van Dokkum
    Department of Clinical Pharmacology, University Medical Center Groningen, Antonius Deusinglaan 1, NL 9713 AV Groningen, The Netherlands
    J Am Soc Nephrol 15:3103-10. 2004

Collaborators

Detail Information

Publications6

  1. ncbi Renal targeting of captopril using captopril-lysozyme conjugate enhances its antiproteinuric effect in adriamycin-induced nephrosis
    Willemijn A K M Windt
    Department of Clinical Pharmacology, Groningen University, Antonius Deusinglaan 1, 9713 AV Groningen, The Netherlands
    J Renin Angiotensin Aldosterone Syst 5:197-202. 2004
    ..We compared the antiproteinuric efficacy of captopril to that of the captopril-lysozyme conjugate in adriamycin-induced proteinuric rats fed with a high-sodium diet...
  2. ncbi Therapeutic resistance to angiotensin converting enzyme (ACE) inhibition is related to pharmacodynamic and -kinetic factors in 5/6 nephrectomized rats
    Willemijn A K M Windt
    Department of Clinical Pharmacology, Groningen Institute for Drug Evaluation, University Medical Center Groningen, University of Groningen, The Netherlands
    Eur J Pharmacol 580:231-40. 2008
    ..32, P=0.003). In conclusion, both pharmacodynamic and -kinetic factors account for the non-response to lisinopril. Whether these can be overcome simply by increasing drug dosage in non-responders should be investigated...
  3. ncbi Myocardial infarction does not further impair renal damage in 5/6 nephrectomized rats
    Willemijn A K M Windt
    Department of Clinical Pharmacology, University Medical Center Groningen, PO Box 196, NL 9700 AD, Groningen, The Netherlands
    Nephrol Dial Transplant 23:3103-10. 2008
    ..The effects of an MI on pre-existing severe renal function loss and the effects of RAAS intervention interrupting this hypothesized cardiorenal interaction are however unknown and clinically even more relevant...
  4. ncbi Renal damage after myocardial infarction is prevented by renin-angiotensin-aldosterone-system intervention
    Willemijn A K M Windt
    Department of Clinical Pharmacology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
    J Am Soc Nephrol 17:3059-66. 2006
    ..VPI treatment seemed to provide no additional renoprotection compared with sole ACEi after 6 wk of treatment in this model, despite a more pronounced ACE-inhibiting effect of VPI...
  5. ncbi Early, but not late therapy with a vasopressin V1a-antagonist ameliorates the development of renal damage after 5/6 nephrectomy
    Willemijn A K M Windt
    Department of Clinical Pharmacology, Groningen Institute for Drug Evaluation GUIDE, University Medical Center Groningen, Antonius Deusinglaan 1 NL 9713 AV Groningen NL 9713, The Netherlands
    J Renin Angiotensin Aldosterone Syst 7:217-24. 2006
    ....
  6. ncbi Myocardial infarction enhances progressive renal damage in an experimental model for cardio-renal interaction
    Richard P E van Dokkum
    Department of Clinical Pharmacology, University Medical Center Groningen, Antonius Deusinglaan 1, NL 9713 AV Groningen, The Netherlands
    J Am Soc Nephrol 15:3103-10. 2004
    ..Finding the underlying mechanism will enable improved protection for both kidneys and heart...