Adriaan A Voors

Summary

Affiliation: University Medical Center Groningen
Country: The Netherlands

Publications

  1. doi The potential role of valsartan + AHU377 ( LCZ696 ) in the treatment of heart failure
    Adriaan A Voors
    Professor of Cardiology, University of Groningen, University Medical Center Groningen, Department of Cardiology, Groningen, The Netherlands
    Expert Opin Investig Drugs 22:1041-7. 2013
  2. doi Trial data resolve gaps in evidence-based treatment
    Adriaan A Voors
    Department of Cardiology, University Medical Center Groningen, University of Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands
    Nat Rev Cardiol 10:67-8. 2013
  3. doi Advanced glycation end-products, anti-hypertensive treatment and diastolic function in patients with hypertension and diastolic dysfunction
    Jasper W L Hartog
    Department of Cardiology, University Medical Center Groningen and University of Groningen, Hanzeplein 1, Groningen, The Netherlands
    Eur J Heart Fail 12:397-403. 2010
  4. doi Differential associations between renal function and "modifiable" risk factors in patients with chronic heart failure
    Tom D J Smilde
    Department of Cardiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
    Clin Res Cardiol 98:121-9. 2009
  5. doi Erythropoietin stimulates normal endothelial progenitor cell-mediated endothelial turnover, but attributes to neovascularization only in the presence of local ischemia
    B Daan Westenbrink
    Department of Cardiology, Thoraxcenter, University Medical Center Groningen, Hanzeplein 1, P O Box 30001, 9700 RB Groningen, The Netherlands
    Cardiovasc Drugs Ther 22:265-74. 2008
  6. pmc Renal dysfunction is associated with shorter telomere length in heart failure
    Liza S M Wong
    Department of Cardiology, University Medical Center Groningen, University of Groningen, Hanzeplein 1, Groningen, The Netherlands
    Clin Res Cardiol 98:629-34. 2009
  7. ncbi Vascular endothelial growth factor is crucial for erythropoietin-induced improvement of cardiac function in heart failure
    B Daan Westenbrink
    Department of Cardiology, Thoraxcenter, University Medical Center Groningen, University of Groningen, Hanzeplein 1, PO Box 30001, Groningen 9700 RB, The Netherlands
    Cardiovasc Res 87:30-9. 2010
  8. doi Functional and hemodynamic cardiac determinants of exercise capacity in patients with systolic heart failure
    Yoran M Hummel
    Department of Cardiology, University Medical Center of Groningen, University of Groningen, Groningen, The Netherlands
    Am J Cardiol 110:1336-41. 2012
  9. doi Inflammation and anaemia in a broad spectrum of patients with heart failure
    Lennaert Kleijn
    Department of Cardiology, University Medical Center Groningen, Groningen, The Netherlands
    Heart 98:1237-41. 2012
  10. pmc Effects of eprosartan on diastolic function and neurohormones in patients with hypertension and diastolic dysfunction
    Adriaan A Voors
    Department of Cardiology, University Medical Centre Groningen, RB, The Netherlands
    Cardiovasc Drugs Ther 24:33-40. 2010

Collaborators

Detail Information

Publications63

  1. doi The potential role of valsartan + AHU377 ( LCZ696 ) in the treatment of heart failure
    Adriaan A Voors
    Professor of Cardiology, University of Groningen, University Medical Center Groningen, Department of Cardiology, Groningen, The Netherlands
    Expert Opin Investig Drugs 22:1041-7. 2013
    ..LCZ696 , a first in class angiotensin receptor neprilysin inhibitor (ARNi), might be an interesting novel drug for the treatment of heart failure...
  2. doi Trial data resolve gaps in evidence-based treatment
    Adriaan A Voors
    Department of Cardiology, University Medical Center Groningen, University of Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands
    Nat Rev Cardiol 10:67-8. 2013
    ..Four studies published in 2012 go some way to resolving this data deficit, and treatment recommendations can now be updated accordingly...
  3. doi Advanced glycation end-products, anti-hypertensive treatment and diastolic function in patients with hypertension and diastolic dysfunction
    Jasper W L Hartog
    Department of Cardiology, University Medical Center Groningen and University of Groningen, Hanzeplein 1, Groningen, The Netherlands
    Eur J Heart Fail 12:397-403. 2010
    ..To investigate the relationship between advanced glycation end-products (AGEs) and diastolic function and the response to blood pressure treatment in patients with hypertension and diastolic dysfunction...
  4. doi Differential associations between renal function and "modifiable" risk factors in patients with chronic heart failure
    Tom D J Smilde
    Department of Cardiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
    Clin Res Cardiol 98:121-9. 2009
    ..Our aim was to determine different pathophysiologic markers that are associated with reduced renal function in CHF...
  5. doi Erythropoietin stimulates normal endothelial progenitor cell-mediated endothelial turnover, but attributes to neovascularization only in the presence of local ischemia
    B Daan Westenbrink
    Department of Cardiology, Thoraxcenter, University Medical Center Groningen, Hanzeplein 1, P O Box 30001, 9700 RB Groningen, The Netherlands
    Cardiovasc Drugs Ther 22:265-74. 2008
    ..We aimed to evaluate whether ischemia is required for erythropoietin (EPO) induced stimulation of endothelial progenitor cells (EPCs) and their related effects on endothelial and cardiac function...
  6. pmc Renal dysfunction is associated with shorter telomere length in heart failure
    Liza S M Wong
    Department of Cardiology, University Medical Center Groningen, University of Groningen, Hanzeplein 1, Groningen, The Netherlands
    Clin Res Cardiol 98:629-34. 2009
    ..We explored the association between leukocyte telomere length, a marker for biological age, and renal function in patients with CHF...
  7. ncbi Vascular endothelial growth factor is crucial for erythropoietin-induced improvement of cardiac function in heart failure
    B Daan Westenbrink
    Department of Cardiology, Thoraxcenter, University Medical Center Groningen, University of Groningen, Hanzeplein 1, PO Box 30001, Groningen 9700 RB, The Netherlands
    Cardiovasc Res 87:30-9. 2010
    ..We intended to delineate the mechanisms of erythropoietin (EPO)-induced cardiac vascular endothelial growth factor (VEGF) production and to establish if VEGF is crucial for EPO-induced improvement of cardiac performance...
  8. doi Functional and hemodynamic cardiac determinants of exercise capacity in patients with systolic heart failure
    Yoran M Hummel
    Department of Cardiology, University Medical Center of Groningen, University of Groningen, Groningen, The Netherlands
    Am J Cardiol 110:1336-41. 2012
    ..Of all echocardiographic parameters at rest, right ventricular function and E/e' were independently and significantly associated with pVo(2), whereas LV ejection fraction at rest was not...
  9. doi Inflammation and anaemia in a broad spectrum of patients with heart failure
    Lennaert Kleijn
    Department of Cardiology, University Medical Center Groningen, Groningen, The Netherlands
    Heart 98:1237-41. 2012
    ..Although inflammation is assumed to be an important cause of anaemia, the association between anaemia and inflammatory markers in patients with HF has not been well established...
  10. pmc Effects of eprosartan on diastolic function and neurohormones in patients with hypertension and diastolic dysfunction
    Adriaan A Voors
    Department of Cardiology, University Medical Centre Groningen, RB, The Netherlands
    Cardiovasc Drugs Ther 24:33-40. 2010
    ..To compare the effects of an angiotensin receptor blocker(ARB)-based regimen versus a non-ARB based regimen on diastolic function and neurohormones in patients with hypertension and diastolic dysfunction...
  11. doi Anaemia is associated with shorter leucocyte telomere length in patients with chronic heart failure
    Liza S M Wong
    Department of Cardiology, University Medical Center Groningen, University of Groningen, Hanzeplein 1, Groningen, The Netherlands
    Eur J Heart Fail 12:348-53. 2010
    ..We hypothesize that short telomere length contributes to the susceptibility to develop anaemia in patients with CHF...
  12. ncbi Renal function dependent association of AGTR1 polymorphism (A1166C) and electrocardiographic left-ventricular hypertrophy
    Tom D J Smilde
    Thorax Center, Department of Cardiology, University Medical Center Groningen, Groningen, The Netherlands
    Am J Hypertens 20:1097-103. 2007
    ..We studied whether renal function modulates the association between RAS polymorphisms and LVH in a cross-sectional study of 8592 inhabitants of Groningen...
  13. ncbi Usefulness of preoperative C-reactive protein and soluble intercellular adhesion molecule-1 level for predicting future cardiovascular events after coronary artery bypass grafting
    Pim van der Harst
    Department of Cardiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
    Am J Cardiol 97:1697-701. 2006
    ....
  14. ncbi High prevalence of microalbuminuria in chronic heart failure patients
    Ruud M A van de Wal
    Department of Cardiology, St Antonius Hospital, Nieuwegein, The Netherlands
    J Card Fail 11:602-6. 2005
    ..In this cross-sectional study, we aim to evaluate the prevalence of microalbuminuria and the association with neurohormonal parameters in severe chronic heart failure patients...
  15. ncbi Vascular function and mild renal impairment in stable coronary artery disease
    Pim van der Harst
    Department of Cardiology, Medical Center Groningen, University of Groningen, The Netherlands
    Arterioscler Thromb Vasc Biol 26:379-84. 2006
    ....
  16. doi The role of advanced glycation end-products and their receptor on outcome in heart failure patients with preserved and reduced ejection fraction
    Suzan Willemsen
    Department of Cardiology, University Medical Center Groningen, Groningen The Netherlands
    Am Heart J 164:742-749.e3. 2012
    ..We studied the predictive value of plasma AGEs N(ε)-(carboxymethyl)lysine (CML), pentosidine, and the soluble form of its receptor (sRAGE) in a large HF population...
  17. doi Urinary neutrophil gelatinase associated lipocalin (NGAL), a marker of tubular damage, is increased in patients with chronic heart failure
    Kevin Damman
    Department of Cardiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
    Eur J Heart Fail 10:997-1000. 2008
    ..In conclusion, renal impairment in CHF patients is not only characterised by decreased eGFR and increased UAE, but also by the presence of tubular damage, as measured by increased urinary NGAL concentrations...
  18. ncbi Fertility, pregnancy and delivery in women after biventricular repair for double outlet right ventricle
    Willem Drenthen
    Department of Cardiology, University Medical Center Groningen, Groningen, The Netherlands
    Cardiology 109:105-9. 2008
    ..To investigate outcome of pregnancy and fertility in women with double outlet right ventricle (DORV)...
  19. ncbi Pregnancy after biventricular repair for pulmonary atresia with ventricular septal defect
    Willem Drenthen
    Department of Cardiology, University Medical Center Groningen, Groningen, The Netherlands
    Am J Cardiol 98:262-6. 2006
    ..Infertility and menstrual cycle disorders do not appear to be more prevalent, except for a high incidence of primary amenorrhea...
  20. doi B-type natriuretic peptide and prognosis in heart failure patients with preserved and reduced ejection fraction
    Dirk J van Veldhuisen
    Department of Cardiology, University Medical Center, University of Groningen, Groningen, The Netherlands
    J Am Coll Cardiol 61:1498-506. 2013
    ....
  21. ncbi Erythropoietin improves cardiac function through endothelial progenitor cell and vascular endothelial growth factor mediated neovascularization
    B Daan Westenbrink
    Department of Cardiology, Thoraxcenter, University Medical Center Groningen, University of Groningen, Hanzeplein 1, PO Box 30001, 9700 RB Groningen, The Netherlands
    Eur Heart J 28:2018-27. 2007
    ..We studied the effects of EPO on homing and incorporation of endothelial progenitor cells (EPC) into the myocardial microvasculature and myocardial expression of angiogenic factors...
  22. ncbi Effect of intensive versus moderate lipid lowering on endothelial function and vascular responsiveness to angiotensin II in stable coronary artery disease
    Pim van der Harst
    Department of Cardiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
    Am J Cardiol 96:1361-4. 2005
    ..05). Endothelium improvement was accompanied by decreased vascular response to angiotensin II (p = 0.039). These findings suggest a mechanism for the clinical benefit of intensive lipid-lowering treatment in coronary heart disease...
  23. ncbi Levels of hematopoiesis inhibitor N-acetyl-seryl-aspartyl-lysyl-proline partially explain the occurrence of anemia in heart failure
    Peter van der Meer
    Department of Cardiology, University Medical Center Groningen, Groningen, The Netherlands
    Circulation 112:1743-7. 2005
    ..The aim of the present study was to determine possible mechanisms linking anemia to renin-angiotensin system activity in CHF patients...
  24. pmc Tubular damage in chronic systolic heart failure is associated with reduced survival independent of glomerular filtration rate
    Kevin Damman
    Department of Cardiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
    Heart 96:1297-302. 2010
    ..The prognostic impact of reduced glomerular filtration rate (GFR) in chronic heart failure (CHF) is increasingly recognised, but little is known about tubular damage in these patients...
  25. doi Effect of fosinopril treatment on serum C-reactive protein levels in patients with microalbuminuria
    Pim van der Harst
    Department of Cardiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
    Am J Cardiol 102:223-5. 2008
    ..Male gender was associated with a significantly larger reduction in CRP compared to female gender. In conclusion, contrary to previous observational studies, no effect of angiotensin-converting enzyme inhibition on CRP levels was found...
  26. ncbi Outcome of pregnancy in women with congenital heart disease: a literature review
    Willem Drenthen
    Department of Cardiology, University Medical Center Groningen, Groningen, The Netherlands
    J Am Coll Cardiol 49:2303-11. 2007
    ..The offspring mortality was high throughout the spectrum and was related to the relatively high rate of premature delivery and recurrence of CHD...
  27. ncbi Low-dose erythropoietin improves cardiac function in experimental heart failure without increasing haematocrit
    Erik Lipsic
    Department of Cardiology, University Medical Center Groningen, University of Groningen, The Netherlands
    Eur J Heart Fail 10:22-9. 2008
    ..However, the increased haematocrit associated with EPO treatment might exert concomitant deleterious effects...
  28. doi Tissue advanced glycation end products are associated with diastolic function and aerobic exercise capacity in diabetic heart failure patients
    Suzan Willemsen
    Department of Cardiology, University Medical Center Groningen, University of Groningen, PO Box 30 001, 9700 RB Groningen, The Netherlands
    Eur J Heart Fail 13:76-82. 2011
    ..We therefore studied the association among tissue AGEs, diastolic function, and aerobic capacity in patients with HF with or without diabetes...
  29. doi Telomere length and psychological well-being in patients with chronic heart failure
    Jardi Huzen
    Department of Cardiology, University Medical Center Groningen, Hanzeplein 1, 9700 RB Groningen, The Netherlands
    Age Ageing 39:223-7. 2010
    ..Shorter telomere length indicates a more advanced biological age. It is unknown whether psychological well-being is associated with telomere length in patients with the somatic condition of chronic heart failure (CHF)...
  30. doi Effects of alagebrium, an advanced glycation end-product breaker, in patients with chronic heart failure: study design and baseline characteristics of the BENEFICIAL trial
    Suzan Willemsen
    Department of Cardiology, University Medical Center Groningen, University of Groningen, PO Box 30 001, 9700 RB Groningen, The Netherlands
    Eur J Heart Fail 12:294-300. 2010
    ..45...
  31. doi Effects of rosuvastatin on coronary flow reserve and metabolic mismatch in patients with heart failure (from the CORONA Study)
    Pim van der Harst
    Department of Cardiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
    Am J Cardiol 105:517-21. 2010
    ....
  32. ncbi Worsening renal function and prognosis in heart failure: systematic review and meta-analysis
    Kevin Damman
    Department of Cardiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
    J Card Fail 13:599-608. 2007
    ..The present study was designed to establish the proportion of patients with HF that exhibits (WRF) and the associated risk for mortality and hospitalization by conducting a systematic review and meta-analysis...
  33. doi Erythropoietin levels in heart failure after an acute myocardial infarction: determinants, prognostic value, and the effects of captopril versus losartan
    Anne M S Belonje
    Department of Cardiology, University Medical Center Groningen, Groningen, The Netherlands
    Am Heart J 157:91-6. 2009
    ..In patients with chronic heart failure, erythropoietin (Epo) levels are increased and related to a poor prognosis. Furthermore, Epo levels in these patients show a weak correlation with hemoglobin levels...
  34. ncbi Anaemia in chronic heart failure is not only related to impaired renal perfusion and blunted erythropoietin production, but to fluid retention as well
    B Daan Westenbrink
    Department of Cardiology, University Medical Center Groningen, University of Groningen, The Netherlands
    Eur Heart J 28:166-71. 2007
    ..The present study aims to investigate the relation between anaemia, renal perfusion, erythropoietin production, and fluid retention in CHF patients...
  35. doi Determinants and prognostic significance of an intra-dialysis rise of cardiac troponin I measured by sensitive assay in hemodialysis patients
    Solmaz Assa
    Division of Nephrology, Department of Internal Medicine, University Medical Center Groningen, The Netherlands
    Clin Res Cardiol 102:439-45. 2013
    ..The aim of this prospective study was to characterize the determinants and prognostic significance of intra-dialysis changes in cTnI using a sensitive assay...
  36. doi Pregnancy in women with corrected tetralogy of Fallot: occurrence and predictors of adverse events
    Ali Balci
    Department of Cardiology, University Medical Center Groningen, Groningen, The Netherlands
    Am Heart J 161:307-13. 2011
    ..Our aim is to investigate the magnitude and determinants of pregnancy outcome in women with corrected ToF...
  37. doi A single dose of erythropoietin in ST-elevation myocardial infarction
    Adriaan A Voors
    Department of Cardiology, University Medical Center Groningen, Groningen, The Netherlands
    Eur Heart J 31:2593-600. 2010
    ..Clinical Trial Registration Information: NCT00449488; http://www.clinicaltrials.gov/ct2/show/NCT00449488?term=voors&rank=2...
  38. doi Both in- and out-hospital worsening of renal function predict outcome in patients with heart failure: results from the Coordinating Study Evaluating Outcome of Advising and Counseling in Heart Failure (COACH)
    Kevin Damman
    Department of Cardiology, University Medical Center Groningen, University of Groningen, Hanzeplein 1, 9700 RB Groningen, The Netherlands
    Eur J Heart Fail 11:847-54. 2009
    ..The effect of worsening renal function (WRF) after discharge on outcome in patients with heart failure is unknown...
  39. ncbi Anaemia and renal dysfunction are independently associated with BNP and NT-proBNP levels in patients with heart failure
    Jochem Hogenhuis
    Department of Cardiology, Thoraxcenter, University Medical Centre Groningen, University of Groningen, PO Box 30 001, 9700 RB Groningen, The Netherlands
    Eur J Heart Fail 9:787-94. 2007
    ..Anaemia may affect B-type natriuretic peptide (BNP) and N-terminal proBNP (NT-proBNP) levels, but this has not been well described in heart failure (HF) patients without the exclusion of patients with renal dysfunction...
  40. ncbi Effects of C-reactive protein and cholesterol on responsiveness in vitro of the internal thoracic artery to angiotensin II in patients having coronary artery bypass grafting
    Pim van der Harst
    Department of Cardiology, Thoraxcenter, University of Groningen, Groningen, The Netherlands
    Am J Cardiol 98:751-3. 2006
    ..In conclusion, our results suggest that CRP and cholesterol act synergistically on vascular responsiveness to angiotensin II...
  41. ncbi Skin-autofluorescence, a measure of tissue advanced glycation end-products (AGEs), is related to diastolic function in dialysis patients
    Jasper W L Hartog
    Department of Cardiology, University Medical Center Groningen and University of Groningen, Groningen, The Netherlands
    J Card Fail 14:596-602. 2008
    ..The aim of our study was to assess whether AGE accumulation in dialysis patients is related to the presence of diastolic dysfunction...
  42. doi Endogenous erythropoietin and outcome in heart failure
    Anne M S Belonje
    Departments of Cardiology, University Medical Center Groningen, Groningen, The Netherlands
    Circulation 121:245-51. 2010
    ..This study aims to analyze the clinical and prognostic value of erythropoietin levels in relation to hemoglobin in a large cohort of HF patients...
  43. ncbi Effect of withdrawal of pravastatin therapy on C-reactive protein and low-density lipoprotein cholesterol
    Pim van der Harst
    Department of Experimental Cardiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
    Am J Cardiol 100:1548-51. 2007
    ..In conclusion, withdrawal from pravastatin treatment resulted in an increase in CRP to approximately baseline levels, which is not related to the increase in LDL cholesterol...
  44. doi Incidence and epidemiology of new onset heart failure with preserved vs. reduced ejection fraction in a community-based cohort: 11-year follow-up of PREVEND
    Frank P Brouwers
    Department of Cardiology, University Medical Center Groningen, University of Groningen, PO Box 30 001, Hanzeplein 1, 9713 GZ Groningen, The Netherlands
    Eur Heart J 34:1424-31. 2013
    ..Data on epidemiology and prediction of new onset HFpEF, compared with HFrEF, have not been described...
  45. pmc Comparison of the temporal release pattern of copeptin with conventional biomarkers in acute myocardial infarction
    Youlan L Gu
    Department of Cardiology, Thorax Center, University Medical Center Groningen, University of Groningen, Hanzeplein 1, PO Box 30001, 9700 RB, Groningen, The Netherlands
    Clin Res Cardiol 100:1069-76. 2011
    ....
  46. ncbi Drawbacks and prognostic value of formulas estimating renal function in patients with chronic heart failure and systolic dysfunction
    Tom D J Smilde
    Department of Cardiology, University Medical Center Groningen, Hanzeplein 1, PO Box 30001, 9700 RB Groningen, The Netherlands
    Circulation 114:1572-80. 2006
    ..Furthermore, we compared the prognostic value of these formulas for cardiovascular outcome with that of true GFR during 12 months of follow-up...
  47. ncbi Mild renal dysfunction is associated with electrocardiographic left ventricular hypertrophy
    Tom D J Smilde
    Department of Cardiology, Thoraxcenter, University Hospital Groningen, Hanzeplein 1, P O Box 30001, 9700 RB Gronigen, The Netherlands
    Am J Hypertens 18:342-7. 2005
    ..We studied the relation between renal dysfunction and LVH in a cross-sectional study in 8592 inhabitants from Groningen, The Netherlands...
  48. ncbi Predictors of angiotensin-converting enzyme inhibitor-induced reduction of urinary albumin excretion in nondiabetic patients
    Ruud M A van de Wal
    St Antonius Hospital, Department of Cardiology, Koekoekslaan 1, 3435 CM, Nieuwegein, The Netherlands
    Hypertension 48:870-6. 2006
    ....
  49. doi Possible association between telomere length and renal dysfunction in patients with chronic heart failure
    Pim van der Harst
    Department of Cardiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
    Am J Cardiol 102:207-10. 2008
    ..Further studies will be needed to determine whether shorter leukocyte telomere length is the cause or consequence in this population and whether it plays a role in the prognosis of renal dysfunction in HF...
  50. pmc Ischemic patterns assessed by positron emission tomography predict adverse outcome in patients with idiopathic dilated cardiomyopathy
    Richard M de Jong
    Thoraxcenter, Department of Cardiology, University Medical Centre Groningen, Hanzeplein 1, P O Box 30 001, 9700 RB, Groningen, The Netherlands
    J Nucl Cardiol 16:769-74. 2009
    ..Our aim was to assess the prognostic relevance of PET-mismatch between stress myocardial perfusion and glucose uptake on clinical outcome in DCM...
  51. doi Effects of alagebrium, an advanced glycation endproduct breaker, on exercise tolerance and cardiac function in patients with chronic heart failure
    Jasper W L Hartog
    Department of Cardiology, University Medical Center Groningen, University of Groningen, PO Box 30 001, 9700 RB, Groningen, The Netherlands
    Eur J Heart Fail 13:899-908. 2011
    ..Our aim was to conduct a prospective, randomized, double-blind, placebo-controlled study to examine the effects of the AGE-breaker alagebrium on exercise capacity and cardiac function in patients with HF...
  52. doi Long term effects of epoetin alfa in patients with ST- elevation myocardial infarction
    Marieke L Fokkema
    Department of Cardiology, University Medical Center Groningen, Hanzeplein 1, 9700 RB, Groningen, The Netherlands
    Cardiovasc Drugs Ther 27:433-9. 2013
    ..The long term effects of erythropoiesis- stimulating agents on cardiovascular morbidity and mortality are unknown, therefore we evaluated clinical events at 1 year after PCI...
  53. doi Urinary N-terminal prohormone brain natriuretic peptide excretion in patients with chronic heart failure
    Gerard C M Linssen
    Department of Cardiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
    Circulation 120:35-41. 2009
    ..The clinical implications and the value of measurement of urinary NT-proBNP in patients with heart failure are largely unknown...
  54. pmc Treatment of heart failure with ACE inhibitors and beta-blockers: what is next? Aldosterone receptor antagonists?
    Iwan C C van der Horst
    Thoraxcenter, Department of Cardiology, University Medical Center Groningen, Groningen, The Netherlands
    Clin Res Cardiol 96:193-5. 2007
  55. ncbi Risk of complications during pregnancy after Senning or Mustard (atrial) repair of complete transposition of the great arteries
    Willem Drenthen
    Department of Cardiology, University Medical Center Groningen, PO Box 30 001, 9700 RB Groningen, The Netherlands
    Eur Heart J 26:2588-95. 2005
    ..To investigate magnitude and determinants of risks during pregnancy in women with Mustard or Senning repair for complete transposition of the great arteries (TGA)...
  56. ncbi High angiotensin II responsiveness is associated with decreased endothelium-dependent relaxation in human arteries
    Adriaan A Voors
    Department of Cardiology, University Medical Center Groningen, Groningen, 9700 RB, The Netherlands
    J Renin Angiotensin Aldosterone Syst 6:145-50. 2005
    ..However, this relation has not been well described in humans. Therefore, we investigated the relation between Ang II responsiveness and EDR in isolated human arteries...
  57. pmc Current and novel renal biomarkers in heart failure
    Kevin Damman
    Department of Cardiology, University Medical Center Groningen, University of Groningen, Hanzeplein 1, 9700 RB Groningen, The Netherlands
    Heart Fail Rev 17:241-50. 2012
    ..In the present review, we summarize current and novel markers that give an assessment of renal function and prognosis in the setting of acute and chronic HF...
  58. ncbi Vascular effects of quinapril completely depend on ACE insertion/deletion polymorphism
    Adriaan A Voors
    Department of Cardiology, Thoraxcenter, University Hospital of Groningen, Groningen 9700, The Netherlands
    J Renin Angiotensin Aldosterone Syst 5:130-4. 2004
    ..The influence of the ACE insertion/deletion (I/D) polymorphism on the effects of ACE-inhibition on vascular responses has not been previously described...
  59. doi Predictive value of tissue Doppler imaging for left ventricular ejection fraction, remodelling, and infarct size after percutaneous coronary intervention for acute myocardial infarction
    Joost P van Melle
    Thoraxcenter, Department of Cardiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
    Eur J Echocardiogr 11:596-601. 2010
    ....
  60. pmc Hemodialysis-induced regional left ventricular systolic dysfunction: prevalence, patient and dialysis treatment-related factors, and prognostic significance
    Solmaz Assa
    Department of Internal Medicine, Division of Nephrology, University Medical Center Groningen, University of Groningen, Hanzeplein 1, Groningen, The Netherlands
    Clin J Am Soc Nephrol 7:1615-23. 2012
    ..This study evaluated the prevalence, time course, and associated patient- and dialysis-related factors of this entity and its association with outcome...
  61. doi N-terminal pro-B-type natriuretic peptide is an independent predictor of cardiovascular morbidity and mortality in the general population
    Gerard C M Linssen
    Department of Cardiology, Thoraxcenter, University Medical Center Groningen, Hanzeplein 1, PO Box 30 001, 9700 RB Groningen, The Netherlands
    Eur Heart J 31:120-7. 2010
    ..However, their prognostic value in the general population is less well established. The purpose of our study was to investigate the prognostic properties of NT-proBNP for death and cardiovascular (CV) events in the general population...
  62. ncbi Correlates of B-type natriuretic peptide and 6-min walk in heart failure patients
    Jochem Hogenhuis
    Department of Cardiology, Thoraxcenter, University Medical Center Groningen, PO Box 30 001, Groningen 9700 RB, The Netherlands
    Int J Cardiol 108:63-7. 2006
    ....
  63. doi Congestion in chronic systolic heart failure is related to renal dysfunction and increased mortality
    Kevin Damman
    Department of Cardiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
    Eur J Heart Fail 12:974-82. 2010
    ..To investigate the relationship between signs and symptoms of congestion, renal impairment and outcome in chronic heart failure (CHF) patients...